nixonix | who gets long covid, theres no single answer. women seem to get it more often, and immunocompromised. and those with persistent abnormalities in certain type of b and t cells | 00:04 |
---|---|---|
nixonix | .title https://www.frontiersin.org/articles/10.3389/fmicb.2021.698169/full | 00:04 |
Brainstorm | nixonix: From www.frontiersin.org: Frontiers | Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms | Microbiology | 00:04 |
nixonix | more often after severe symptoms, but then some get it after mild or asymptomatic infection. sometimes afterwards, when acute symptoms have long gone | 00:05 |
Rpifan | Well I've got hiv | 00:08 |
foo | nixonix: I see. I'd love to take a few tests and know the probability of getting it myself or such | 00:09 |
nixonix | ...persistent reservoirs of SARS-CoV-2 in certain tissues, re-activation of neurotrophic pathogens such as herpesviruses under conditions of COVID-19 immune dysregulation, SARS-CoV-2 interactions with host microbiome/virome communities... | 00:10 |
nixonix | list of possible reasons is long | 00:10 |
nixonix | i dont know much about hiv, but adjuvants can be risky for immunocompromised. novavax is adjuvanted, so mrna vaccines prob less risky | 00:12 |
nixonix | .title https://www.statnews.com/2021/04/16/next-generation-covid-19-vaccines-are-supposed-to-be-better-some-experts-worry-they-could-be-worse/ | 00:14 |
Brainstorm | nixonix: From www.statnews.com: Some experts fear next-generation Covid vaccines may be worse | 00:14 |
nixonix | “Basically, I think of original antigenic sin as some sort of hierarchy in immune memory, meaning you preferentially boost what you’ve seen before, at the expense of developing responses to the new stuff,” Cobey said. “It could impact the effectiveness of [Covid] vaccine going forward.” | 00:16 |
Rpifan | Interesting so novavax is básically better in every way possible | 00:18 |
Rpifan | But it got to the finish line a bit too late | 00:18 |
Rpifan | But it seems it is being deployed in the UK | 00:18 |
nixonix | you never know for sure before you try that "mix and match", you may commit a sin, get a boost from broader response, get ADE or some kind of interference | 00:20 |
nixonix | i dont get it how you got it to be better in every way. adjuvants are always a risk | 00:21 |
nixonix | but then again, for immunocompromised it may be good, because they might not get enough effect from two doses of mrna vaccine. it depends, i guess | 00:25 |
nixonix | and not all from 3 doses, there was some study if i find | 00:25 |
nixonix | .title https://jamanetwork.com/journals/jama/fullarticle/2782538?guestAccessKey=0471fe15-f223-43d7-b5c1-ac42d375e9a9 | 00:27 |
Brainstorm | nixonix: From jamanetwork.com: Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses | Nephrology | JAMA | JAMA Network | 00:27 |
nixonix | anyways, my idea was, how about a bit of alum or something with mrna vaccine for immunocompromised, maybe it would work | 00:28 |
LjL | i am interested in Novavax and i think it's promising (especially if they find some bigger company to *produce* it) but going ahead and saying it's "basically better in every way possible" seems like jumping the gun a tiny bit | 00:28 |
LjL | for starters it's worse in that it has not really been deployed yet, which in turn means we have no information on how well it fares with delta | 00:30 |
LjL | (although the information we do have for other vaccines seems... less than consistent, anyway) | 00:30 |
nixonix | i tried to google if QTNSPRRAR would be a superantigenic sequence, found a twitter thread with interesting participants (and the chinese spy tracking me noticed and disconnected the server) https://twitter.com/daoyu15/status/1406773245915787266 | 00:44 |
LjL | nixonix, don't know if they are interesting, but i clicked on one mostly at random ("Darko Dlaka") and his pinned tweet is a retweet of "Fauci racket. Create pandemic. Jam vaccine down kids throats. Profits for big pharma. Rinse and repeat. #firefauci" | 00:58 |
LjL | speaking of which had i not clicked something about Fauci yesterday and then forgot to read it | 00:59 |
LjL | ah yeah just this https://www.bbc.com/news/world-us-canada-57962387 | 01:00 |
LjL | <Brainstorm> New from r/WorldNews: worldnews: Tunisia on edge as president suspends parliament, fires PM → https://is.gd/WVsmob | 01:12 |
LjL | http://offloop.net/covid19/?default=EU;Tunisia&byPopulation=yes&cumulative=no&smooth=yes | 01:12 |
LjL | “I ask how some can talk of a coup d’etat,” Radio Mosaique quoted Saied as saying. “I studied and taught law. I applied the constitution, respecting its dispositions.” | 01:14 |
LjL | The president invoked a constitutional article that allows him to assume executive power for an unspecified period of time in cases of “imminent danger threatening the institutions of the nation and the independence of the country and hindering the regular functioning of the public powers.” | 01:14 |
LjL | okay, well, that's a constitution that soooooorta calls for a coup | 01:14 |
Brainstorm | New from r/WorldNews: worldnews: U.S. issues 'Do Not Travel' advisories for Spain, Portugal over COVID-19 cases → https://is.gd/5yCyWo | 01:34 |
Brainstorm | New from University of Washington: Alumni Spotlight: The Storied Career of Beatriz Thomé (MPH '10): BT pic.jpeg Over the last two decades, Beatriz Thomé, MD, MPH, PhD, has worked as a pediatrician, research manager, university lecturer, and monitoring & evaluation specialist in countries as geographically disperse as Mozambique, Switzerland, and her [... want %more?] → https://is.gd/YIr4dU | 01:44 |
Brainstorm | New from Ars Technica: Science: COVID surge in unvaccinated is pushing US to more mandates, masks, mitigation → https://is.gd/bJVjEH | 01:54 |
Brainstorm | Updates for China: +58 cases (now 98605) since 20 hours ago — Netherlands: +2141 cases (now 1.9 million) since 20 hours ago — United Kingdom: +19363 cases (now 5.7 million), +14 deaths (now 129309) since 20 hours ago — Canada: +261 cases (now 1.4 million) since 20 hours ago | 02:38 |
Brainstorm | New from r/WorldNews: worldnews: Japan Covid Cases Surge As Olympics Get Underway → https://is.gd/IM9Med | 02:46 |
Brainstorm | Updates for Mauritius: +397 cases (now 3785) since 3 days ago — Oman: +5484 cases (now 294526), +273 deaths (now 3771) since 11 days ago | 03:40 |
Brainstorm | New from Politico: After the crisis: Economic lessons from the pandemic: In response to the coronavirus, Europe embraced a new model for managing crises. It must not return to the past. → https://is.gd/4pvnBy | 04:08 |
Brainstorm | Updates for Burundi: +245 cases (now 6373) since 3 days ago — S. Sudan: +97 cases (now 11014), +1 deaths (now 118) since 11 days ago | 04:30 |
Brainstorm | Updates for Norway: +330 cases (now 136097) since a day ago — Fr. Polynesia: +107 cases (now 19392), +1 deaths (now 146) since 3 days ago — France: +18 deaths (now 111735) since 23 hours ago | 05:33 |
Brainstorm | New from The Indian Express: World: UN: Covid hitting poor and conflict nations worse this year → https://is.gd/N1UFNQ | 05:41 |
LjL | %cases norway | 05:42 |
Brainstorm | LjL: In Norway, there are 136097 confirmed cases (2.5% of all people) and 799 deaths (0.6% of cases) as of 9 minutes ago. 6.6 million tests were done (2.1% positive). Fatality can be expected to lie between 0.7% (assuming prevalence as in tests) and less than 0.9% (considering only deaths and recoveries). +330 cases since a day ago. See https://offloop.net/covid19/?default=Norway | 05:42 |
LjL | so few deaths... how does it happens? okay, the cases aren't enough to completely clog the healthcare machinery, but still, it's a long way from 0.6% to 3% or more | 05:44 |
Brainstorm | New from r/WorldNews: worldnews: New Zealand pandemic policies pushed 18,000 children into poverty → https://is.gd/q8y258 | 05:51 |
Brainstorm | Updates for Mauritania: +253 cases (now 24008), +3 deaths (now 538) since a day ago — United Kingdom: +18367 cases (now 5.7 million), +11 deaths (now 129313) since 23 hours ago — Netherlands: +1942 cases (now 1.9 million), +1 deaths (now 17944) since 23 hours ago — Canada: +484 cases (now 1.4 million) since 23 hours ago | 06:34 |
Brainstorm | New from The Indian Express: World: New York City, California mandate COVID-19 vaccines for government workers → https://is.gd/RjbQKt | 06:42 |
Brainstorm | New from r/WorldNews: worldnews: FDA asks Pfizer, Moderna to test their vaccines in more children to help rule out safety issues → https://is.gd/ZWR3jY | 07:33 |
Brainstorm | Updates for California, United States: +11620 cases (now 3.9 million), +32 deaths (now 64267) since a day ago — Andalusia, Spain: +9919 cases (now 688491), +6 deaths (now 10157) since 2 days ago — Madrid, Spain: +7650 cases (now 795937) since 2 days ago — Louisiana, United States: +7592 cases (now 520435), +14 deaths (now 10914) since 2 days ago | 07:37 |
Brainstorm | New from The Indian Express: World: Russia approves trials of combined AstraZeneca and Sputnik V vaccine → https://is.gd/J5fULU | 08:05 |
Brainstorm | Updates for India: +29689 cases (now 31.4 million), +278 deaths (now 421254) since 11 hours ago | 08:39 |
Brainstorm | New from r/Coronavirus: Daily Discussion Thread | July 27, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/V55w0a | 09:07 |
Brainstorm | Updates for Uzbekistan: +789 cases (now 125784), +6 deaths (now 845) since 23 hours ago | 09:41 |
Brainstorm | New from EMA: What's new: General: COVID-19 vaccines: authorised → https://is.gd/xlCRKA | 09:54 |
Brainstorm | New from The Indian Express: World: Pfizer, AstraZeneca vaccine antibody levels may decline after 2-3 months: Lancet study → https://is.gd/1ll7Eg | 10:05 |
Brainstorm | New from The Indian Express: World: The most influential spreader of coronavirus misinformation online → https://is.gd/lHAa7e | 10:58 |
zutt | %cases indonesia | 11:06 |
Brainstorm | Updates for Estonia: +193 cases (now 132717) since a day ago | 11:06 |
Brainstorm | zutt: In Indonesia, there are 3.2 million confirmed cases (1.2% of all people) and 84766 deaths (2.7% of cases) as of 21 hours ago. 17.0 million tests were done (18.8% positive). Fatality can be expected to lie between 0.2% (assuming prevalence as in tests) and less than 3.2% (considering only deaths and recoveries). +28228 cases, +1487 deaths since 23 hours ago. See https://offloop.net/covid19/?default=Indonesia | 11:06 |
Brainstorm | zutt: If you know of an official or otherwise good site for data about Indonesia, with a reasonably short URL, please %tell LjL about it. | 11:06 |
zutt | %cases thailand | 11:06 |
Brainstorm | zutt: In Thailand, there are 526828 confirmed cases (0.8% of all people) and 4264 deaths (0.8% of cases) as of 3 hours ago. 1.2 million tests were done (44.1% positive). +14150 cases, +118 deaths since a day ago. See https://offloop.net/covid19/?default=Thailand | 11:06 |
Brainstorm | zutt: If you know of an official or otherwise good site for data about Thailand, with a reasonably short URL, please %tell LjL about it. | 11:06 |
Brainstorm | New from BMJ: Ewoud Schuit, Irene K Veldhuijzen, Roderick P Venekamp, Wouter van den Bijllaardt, Suzan D Pas, Esther B Lodder, Richard Molenkamp, Corine H GeurtsvanKessel, Jans Velzing, Robin C Huisman, Lieke Brouwer, Timo L Boelsums, Gregorius J Sips, Kimberly S M Benschop, Lotty Hooft, Janneke H H M van de Wijgert, Susan van den Hof, Karel G M Moons: [... want %more?] → https://is.gd/Z9TY37 | 11:30 |
Brainstorm | Updates for Georgia: +3666 cases (now 407689), +17 deaths (now 5731) since a day ago | 11:33 |
finely[m] | Russian troll factory at work. | 11:55 |
finely[m] | "Just spend the same money on TikTok creators, YouTube creators. The whole ecosystem is perfectly built for maximum efficiency of disinformation right now." | 11:55 |
finely[m] | https://www.bbc.com/news/blogs-trending-57928647 | 11:55 |
zutt | it really is | 12:01 |
zutt | this whole social media ecosystem we have today is filled with misinformation, and i'm convinced that its not just russians playing with this power (unrelated to covid) | 12:05 |
finely[m] | There was a report years ago about the US developing software to manage multiple online identities for disinformation campaigns. In a sense it is the Russians again using weapons developed by others against them. | 12:09 |
finely[m] | Of course it is the whole industry created by companies to control damaging information being hijacked by nation states. | 12:10 |
Brainstorm | New from ScienceNews: Why it’s still so hard to find treatments for early COVID-19: Small studies, unexpected side effects and incomplete information about how drugs work can stymie clinical trials for drugs that can treat COVID-19. → https://is.gd/EwSrbt | 12:12 |
zutt | yeah | 12:12 |
zutt | in the recent years, I honestly have grown to hate the social medias that I partake in (which is basically just youtube, if we don't count IRC ;P) | 12:13 |
zutt | it's all just a... big TV-shop, or a shopping channel.. whatever it's called in other parts of the world | 12:13 |
finely[m] | IRC is more antisocial media in my mind :) | 12:14 |
zutt | yeah, I am so thankful that theres no ads or brand deals or sponsorships in IRC, lol :P | 12:15 |
zutt | ^inb4 we start seeing "This message was sponsored by *random vpn service*" on Brainstorm's messages | 12:17 |
finely[m] | It the lack of massive engagement AI systems that make the difference. Have you seen The Social Dilemma? | 12:17 |
zutt | nope, haven't seen that one | 12:18 |
finely[m] | Great doco. It telling the people who designed these systems don't let their kids use them. | 12:20 |
zutt | gotta add it to my watch-list | 12:23 |
Brainstorm | New from BMJ: Covid-19: One third of trainees are affected by burnout, GMC survey finds: The covid-19 pandemic has increased the level of burnout in trainees and risks reversing recent improvements to their workload and wellbeing, the General Medical Council (GMC) has warned.Of the 46... → https://is.gd/IRBnr3 | 12:53 |
Brainstorm | New from r/WorldNews: worldnews: Greater Sydney lockdown to be extended by four weeks as Covid cases continue to rise → https://is.gd/Nqf6Kf | 13:03 |
Brainstorm | New from r/WorldNews: worldnews: Pfizer, AstraZeneca Vaccine Antibody Levels May Decline In 2-3 Months: Lancet Study → https://is.gd/t0bMe6 | 13:33 |
zutt | %cases uk | 13:34 |
Brainstorm | zutt: In United Kingdom, there are 5.7 million confirmed cases (8.6% of all people) and 129316 deaths (2.3% of cases) as of 5 hours ago. 237.8 million tests were done (2.4% positive). +18367 cases, +11 deaths since 23 hours ago. See https://coronavirus.data.gov.uk/ | 13:34 |
Brainstorm | Updates for Finland: +612 cases (now 103851) since 6 hours ago | 13:37 |
Brainstorm | New from BMJ: Conflicted and confused? Health harming industries and research funding in leading UK universities: University researchers face growing expectations to engage with commercial sources of funding. This pressure is likely to increase in the context of the covid-19 squeeze1 and, in the UK, both Brexit... → https://is.gd/LGVuEG | 14:26 |
Brainstorm | Updates for Iran: +34951 cases (now 3.8 million), +357 deaths (now 89479) since a day ago — Azerbaijan: +468 cases (now 341183), +2 deaths (now 5011) since 22 hours ago | 14:39 |
Brainstorm | New from BMJ: Covid-19: China stymies investigation into pandemic’s origins: Prospects for a serious accounting of the origins of the covid-19 pandemic seemed more distant than ever this week, as the US and China traded barbs at a high level diplomatic meeting on 26 July,... → https://is.gd/F1crUQ | 14:47 |
specing | at this point why not just assume it was china that started it and put it on them to prove otherwise? | 14:49 |
specing | We could even assume that they intentionally started it | 14:51 |
Brainstorm | New from r/WorldNews: worldnews: Africa wants to produce a coronavirus vaccine — and Big Pharma’s not happy → https://is.gd/DycHuc | 15:08 |
specing | ^ Imagine getting non-western vaccines in the west. nah nah, not happening | 15:28 |
specing | "politicians: You can pick vaccines now, no reason not to get vaccinated" | 15:29 |
Brainstorm | New from Politico: Ireland to offer coronavirus jabs to children aged 12 to 15: Irish health chief pledges to inoculate teens 'promptly' as pubs reopen to vaccinated adults with unvaccinated kids. → https://is.gd/tfgFYQ | 15:29 |
specing | "reality: only 4/20 vaccines available" | 15:29 |
Brainstorm | New from BBC Health: Covid: Alert over inaccurate thermometers bought in UK: Sales have increased in the pandemic but some products are not fit for purpose, UK regulator warns. → https://is.gd/6eAfMt | 16:00 |
Brainstorm | Updates for Bangladesh: +14925 cases (now 1.2 million), +258 deaths (now 19779) since a day ago — Serbia: +290 cases (now 720643), +3 deaths (now 7108) since a day ago — Nepal: +2726 cases (now 685673), +20 deaths (now 9758) since a day ago — Switzerland: +853 cases (now 715267) since a day ago | 16:06 |
Brainstorm | Updates for Antigua and Barb.: +8 cases (now 1288) since 2 days ago | 16:31 |
Brainstorm | New from BMJ: Covid-19: Countries dump vaccines as demand slumps and sharing proves difficult: The US, the UK, and the Netherlands face throwing away tens of thousands of covid-19 vaccine doses that are due to expire.The US had already thrown out more than 180 000 vaccine doses by the end of... → https://is.gd/jEmjDP | 16:32 |
-RSSBot[LjLmatrix- Feed: Riunione del Cipess del 27 luglio 2021 ( https://www.governo.it/it/articolo/riunione-del-cipess-del-27-luglio-2021/17529 ) | 16:38 | |
Brainstorm | New from The Indian Express: World: Singapore eyes starting quarantine-free travel in September → https://is.gd/51WhYF | 16:53 |
Brainstorm | New from ClinicalTrials.gov: (news): Mental and Psychological Problems and Insomnia Disorder of Medical Staff in Hospital With Infected COVID-19 Patients → https://is.gd/GMHls0 | 17:04 |
Brainstorm | Updates for India: +29773 cases (now 31.4 million), +378 deaths (now 421354) since 20 hours ago | 17:08 |
Brainstorm | Updates for Iraq: +12185 cases (now 1.6 million), +71 deaths (now 18418) since a day ago — United Kingdom: +30794 cases (now 5.7 million) since 23 hours ago — North Macedonia: +38 cases (now 156124) since 20 hours ago — Italy: +467 cases (now 4.3 million), +1 deaths (now 127972) since 22 hours ago | 18:11 |
Brainstorm | New from r/WorldNews: worldnews: Norovirus warning as bug spreads in England after lockdown eased → https://is.gd/LzOSKT | 18:38 |
Brainstorm | Updates for Morocco: +6971 cases (now 588448), +27 deaths (now 9638) since a day ago | 19:13 |
Brainstorm | New from In The Pipeline: A New Small Molecule Candidate for Malaria: Here’s a new paper with a surprise: a small molecule that appears to be very effective against malaria, with what may be a high barrier to developing resistance (C&E News coverage here). It’s from a large multicenter (multicontinent) team, and the chemical matter has its origins [... want %more?] → https://is.gd/IXD6fn | 19:29 |
Brainstorm | Updates for Canada: +14 deaths (now 26558) since 16 hours ago | 19:31 |
Brainstorm | New from StatNews: Opinion: A solution to the murky legal status of vaccine mandates: rewrite vaccine EUAs: The nation should not tolerate more deaths, hospitalizations, shutdowns, and economic and personal ruin. Rewriting vaccine EUAs is a key solution to promptly instituting much-needed vaccine mandates. → https://is.gd/TySeYC | 19:50 |
Brainstorm | New from Gazzetta Ufficiale italiana: AGENZIA ITALIANA DEL FARMACO - DETERMINA 26 luglio 2021: Estensione dell'indicazione terapeutica del vaccino anti-Covid 19Spikevax. (Determina n. 111/2021). (21A04622) → https://is.gd/jI2nuD | 20:00 |
Brainstorm | Updates for Spain: +26399 cases (now 4.4 million) since 23 hours ago — India: +33306 cases (now 31.4 million), +484 deaths (now 421460) since 23 hours ago | 20:40 |
LjL | apparently Moderna is called Spikevax now | 20:51 |
LjL | https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax-previously-covid-19-vaccine-moderna | 20:51 |
specing | yes | 20:51 |
Brainstorm | New from Ars Technica: Gaming & Culture: Facebook recalls 4 million Quest 2 VR face masks over “rashes and hives” → https://is.gd/y9ujQp | 20:51 |
LjL | lol, regex match on "face masks" | 20:52 |
LjL | (who called VR headsets "face masks" before anyway?) | 20:53 |
ublx | clickbaiters looking to draw some covid related clicks? | 20:53 |
LjL | makes me suspect that | 20:56 |
Brainstorm | New from r/WorldNews: worldnews: Tokyo Olympics: COVID-19 cases in city rise by 149% in a week – but officials resist new calls to suspend Games → https://is.gd/OVZ6MT | 21:12 |
Brainstorm | Updates for France: +16777 cases (now 6.0 million), +34 deaths (now 111754) since 18 hours ago | 21:35 |
Brainstorm | New from CIDRAP: News Scan for Jul 27, 2021: Republican COVID vaccine acceptance COVID-19 prediction tools Malaria mRNA vaccine project → https://is.gd/0f1Chp | 22:14 |
nixonix | interesting idea, somebody wrote on some forum. does the summer have an effect that reduces the likelihood to get hospitalized from sars2 infection | 22:54 |
nixonix | which would be due to higher vitamin d levels. last fall it took quite awhile before deaths increased, after cases went up. apparently mostly due to younger ppl usually get it first when its soaring | 22:56 |
LjL | there's apparently a lot of "vitamin D works against covid" vs "vitamin D against covid is a myth" controversy, and i'm not sure which side i'm on | 22:58 |
LjL | i guess i'm on the side that most people are vitamin D deficient in the winter, at least in Europe, so supplementing can't hurt | 22:59 |
nixonix | the truth is possibly somewhere in between | 23:00 |
nixonix | hard to say for sure, since they used quite low levels in studies | 23:00 |
nixonix | .title https://www.medrxiv.org/content/10.1101/2021.07.23.21261030v1 | 23:00 |
Brainstorm | nixonix: From www.medrxiv.org: Breakthrough Symptomatic COVID-19 Infections Leading to Long Covid: Report from Long Covid Facebook Group Poll | medRxiv | 23:00 |
nixonix | very biased sample, but maybe interesting | 23:00 |
nixonix | somebody collected bunch of brain studies in a twitter thread https://twitter.com/AndrewEwing11/status/1419688098800275459 | 23:03 |
nixonix | .title https://www.nature.com/articles/d41586-021-01693-6 | 23:03 |
Brainstorm | nixonix: From www.nature.com: COVID and the brain: researchers zero in on how damage occurs | 23:03 |
nixonix | .title https://bjo.bmj.com/content/early/2021/07/08/bjophthalmol-2021-319450 | 23:06 |
Brainstorm | nixonix: From bjo.bmj.com: Corneal confocal microscopy identifies corneal nerve fibre loss and increased dendritic cells in patients with long COVID | British Journal of Ophthalmology | 23:06 |
nixonix | .title https://www.moneycontrol.com/news/business/no-longer-hidden-victims-children-are-dying-as-the-coronavirus-surges-in-indonesia-covid-19-7223251.html | 23:07 |
Brainstorm | nixonix: From www.moneycontrol.com: No Longer 'hidden Victims,' Children Are Dying As The Coronavirus Surges In Indonesia | 23:07 |
nixonix | .title https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronavirusayearlikenoother/2021-03-15 | 23:10 |
nixonix | pic 1 | 23:10 |
Brainstorm | nixonix: From www.ons.gov.uk: Coronavirus: a year like no other - Office for National Statistics | 23:10 |
LjL | i heard about Indonesia, but are a lot of children dying because Delta is worse for them than older variants used to be, or just because there are so many cases and it's so out of control that inevitably many children are affected too? | 23:12 |
LjL | how is it that these "hidden victims" were, until recently, considered by practically everyone to be not immune to covid but almost | 23:12 |
LjL | "hidden victims" implies that was never true and it was wrong (or a lie) all along...? | 23:13 |
Raf[m] | I haven't read any evidence that the delta variant is actually more severe in symptoms, especially not toward children. only, that it is more transmissibile | 23:15 |
Brainstorm | New from Ars Technica: Science: CDC mask reversal: Vaccinated should wear masks in many settings amid surge → https://is.gd/eSEsP9 | 23:16 |
nixonix | i dont know, a bit strange when in the west the problem with children is mostly those possible damages to brain, organs etc, not actual deaths | 23:17 |
Raf[m] | you mean MIS-C? | 23:18 |
nixonix | stats then, when even in most western countries large share of deaths were missing from official covid deaths. although in some countries like easteren europe and some latin american countries deaths are reported more diligently | 23:18 |
Raf[m] | severe cases of COVID in children is extremely rare | 23:18 |
nixonix | but check bangladesh, strangely there was no delay when cases went down, deaths too, then both up again | 23:19 |
Raf[m] | if anything the conspiracies say the opposite, that COVID cases are overreported to receive more funding and aid | 23:19 |
nixonix | and some russian claimed their case numbers come with 1.5 months delay | 23:19 |
nixonix | its possible that some countries overreport for that reason. but many underreport, including deaths in many western countries | 23:21 |
nixonix | .title https://europepmc.org/article/ppr/ppr356279?javascript_support=no | 23:26 |
Brainstorm | nixonix: From europepmc.org: Clinical and Virological Features of SARS-CoV-2 Variants of Concern: A Retrospective Cohort Study Comparing B.1.1.7 (Alpha), B.1.315 (Beta), and B.1.617.2 (Delta) - Abstract - Europe PMC | 23:26 |
specing | LjL: joerg http://www.dhmo.org/facts.html :D | 23:27 |
LjL | specing, it's particularly dangerous in the form of hail, i think some parts of my country and others experienced lately | 23:31 |
nixonix | .title https://www.newscientist.com/article/2280832-delta-variant-doubles-risk-of-covid-19-hospitalisations-study-shows/ | 23:31 |
Brainstorm | nixonix: From www.newscientist.com: Delta variant doubles risk of covid-19 hospitalisations, study shows | New Scientist | 23:31 |
nixonix | so im not sure what you meant by "i havent read any evidence", but theres some | 23:32 |
nixonix | if you meant only conclusive evidence, theres very little such in this world | 23:32 |
specing | LjL: yeah. I wonder if the next that comes to link massive vaccine fatalities will recognise it for what it is :D | 23:33 |
specing | I'm going to run my own study | 23:33 |
nixonix | .title https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01358-1/fulltext | 23:34 |
Brainstorm | nixonix: From www.thelancet.com: The Lancet | The best science for better lives | 23:34 |
LjL | Raf[m], nixonix, i don't know about evidence, because those short "cards" don't have references, but the UK advisory body has long considered Delta to be likely to be more severe, although, iirc, with a "moderate" or "low" level of evidence (while "high" that it's more transmissible) | 23:35 |
nixonix | and also uk kent variant to be more severe than older variants (by 50% or so) | 23:40 |
nixonix | not everyone agrees on 617.2 part though (severity) | 23:42 |
nixonix | but anyways, there IS evidence. just maybe not conclusive | 23:42 |
LjL | i suspect vaccines make the picture less clear (fortunately?) | 23:42 |
LjL | i meant to link that UK thing i was referring to, but i'm having trouble finding it | 23:43 |
LjL | actually i think i had added the "source" page for that table to my links page since i kept being unable to find it again | 23:43 |
nixonix | link i to me if you find it some day. the one mentioning those low and high, i dont remember seeing it | 23:43 |
LjL | so let me check there :D | 23:44 |
LjL | nixonix, i think it's kind of a dumbed down version of the facts for government people | 23:44 |
LjL | (just my impression of what it looks to be meant for) | 23:44 |
LjL | ah goos, i *did* add it | 23:45 |
LjL | %link variant risk assessment | 23:45 |
Brainstorm | LjL, https://www.cogconsortium.uk/wp-content/uploads/2020/12/Report-1_COG-UK_19-December-2020_SARS-CoV-2-Mutations.pdf (COG-UK update on SARS-CoV-2 Spike mutations of special interest) comes after the https://www.reuters.com/article/uk-health-coronavirus-britain-strain/uk-says-new-coronavirus-strain-is-more-infectious-but-vaccines-should-still-work-idUSKBN28T0KL (UK government [... want %more?] | 23:45 |
LjL | uhm not this, but anyway | 23:45 |
nixonix | its a way to classify studies in metastudies, estimate their level of efidence, and weigh it according to it | 23:45 |
LjL | nixonix, https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-of-concern-variant-risk-assessments just click on the latest one, i used to only have a direct link to one of them, but they update them weekly | 23:46 |
nixonix | i dont really like the method in those metastudies. im more like, throw away the garbage and see if you have any quality stuff left | 23:46 |
LjL | this is not quite a meta review though, it's literally just a "card" | 23:46 |
LjL | i mean, i'm sure its information is derived from reviews and whatnot, but it doesn't mention the sources so i feel it's mainly to convey the severity of the situation to other UK bodies | 23:47 |
LjL | the red color means the risk of the thing is high, and then they give you the level of evidence for it. yes it's similar to what metastudies do except quite dumbed down | 23:48 |
nixonix | those variant papers have "high" and "low" classifications? i jsut had couple of them open | 23:49 |
LjL | i'm confused what you mean | 23:49 |
LjL | i'm looking at like https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1005395/23_July_2021_Risk_assessment_for_SARS-CoV-2_variant_Delta.pdf | 23:50 |
LjL | the column "Confidence" has high and low classifications | 23:50 |
LjL | of note that they increased the risk about "immunity after natural infection", for Delta, from amber to red | 23:51 |
LjL | (still with "low" confidence though) | 23:51 |
nixonix | ah, that one has, i just didnt have that one open (i downloaded it another day though) | 23:51 |
LjL | nixonix, https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/988614/Risk_assessment_framework_for_SARS-CoV-2_variants_20210521.pdf this document explains what the color coding means (and also the confidence, but those are kinda easy to guess) | 23:53 |
LjL | note that something that causes a "low" confidence, they state, is "no experience with previous similar incidents" | 23:53 |
LjL | which is kinda... yeah :| | 23:53 |
nixonix | why they have to put every new little crap in pdf files, why not just update a web page | 23:54 |
nixonix | canada plans to stop or reduce tracking variants apparently. maybe they think its soon dominant, so no need anymore https://twitter.com/jvipondmd/status/1419390353401016320 | 23:57 |
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