libera/##covid-19/ Sunday, 2021-12-12

BrainstormUpdates for Switzerland: +2 deaths (now 11785) since 22 hours ago00:07
BrainstormUpdates for Mozambique: +443 cases (now 153408) since a day ago00:32
de-facto.title https://www.nejm.org/doi/full/10.1056/NEJMoa211562400:49
Brainstormde-facto: From www.nejm.org: BNT162b2 Vaccine Booster and Mortality Due to Covid-19 | NEJM00:49
de-facto"We obtained data for all members of Clalit Health Services who were 50 years of age or older at the start of the study and had received two doses of BNT162b2 at least 5 months earlier. The mortality due to Covid-19 among participants who received the booster during the study period (booster group) was compared with that among participants who did not receive the booster (nonbooster group)."00:50
de-facto"A total of 843,208 participants met the eligibility criteria, of whom 758,118 (90%) received the booster during the 54-day study period."00:50
de-facto"Death due to Covid-19 occurred in 65 participants in the booster group (0.16 per 100,000 persons per day) and in 137 participants in the nonbooster group (2.98 per 100,000 persons per day). The adjusted hazard ratio for death due to Covid-19 in the booster group, as compared with the nonbooster group, was 0.10 (95% confidence interval, 0.07 to 0.14; P<0.001)."00:50
de-factoabout the Delta B.1.617.2 variant in Israel00:51
de-facto"Participants who received a booster at least 5 months after a second dose of BNT162b2 had 90% lower mortality due to Covid-19 than participants who did not receive a booster."00:52
BrainstormNew from COVID on Twitter: Axel Ellrodt (@EllrodtAxel): Les vaccins nasaux induisent des IgA et favorisent une meilleure immunité de protection croisée contre les variants viraux, et suggèrent leur utilité pour combattre les variants préoccupants du COVID-19. twitter.com/VirusesImmunit… → https://twitter.com/EllrodtAxel/status/146981515106711142401:05
BrainstormUpdates for Madagascar: +994 cases (now 45794), +8 deaths (now 980) since 5 days ago — Canada: +7022 cases (now 1.8 million) since 22 hours ago — United Kingdom: +52645 cases (now 10.8 million) since 22 hours ago01:34
LjLde-facto, to me unless i'm reading it wrong somehow... that seems like the ones without a booster have a *horrendously high* death rate. 3 per 100k per day? does that translate to 3% in 100 days?01:53
LjLin which case, sure, it's better with the booster, but the other ones are still fully vaccinated, so *what the heck is going on*?01:54
LjLinitially a 3% death rate *within cases* was already considered, when it was happening in italy, implausibly high and everybody was saying "they're undercounting cases"01:54
BrainstormUpdates for Panama: +356 cases (now 480573), +1 deaths (now 7386), +7682 tests (now 4.3 million) since 22 hours ago01:59
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): A study from Israel pegs the neutralization loss for Omicron vs original strain at 16x (4x worse than Delta), rather than the 40x in the top post. Both the Israel and the top study used actual SARSCoV2 virus.reuters.com/world/middle-e… → https://twitter.com/michaelzlin/status/146983320189596057902:01
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): The 40x is starting to look like a mistake/outlier. Perhaps the titer of one of the two viruses (D614G "original" or Omicron) was a bit off. Pfizer had seen a 25x loss of neutralizing titers for Omicron vs reference strain, using [... want %more?] → https://twitter.com/michaelzlin/status/146983320397632307402:10
de-factoLjL, 10^2 * 3 / 10^5 = 3 / 10^(5-2) = 3/10^3 = 0,003 or 0.3%02:18
LjLoh whoops02:19
LjLstill a lot though :(02:19
LjL3% would have been just crazy, 0.3% is just a lot02:19
de-facto.cases Italy02:19
Brainstormde-facto: Italy has had 5.2 million confirmed cases (8.6% of all people) and 134765 deaths (2.6% of cases; 1 in 447 people) as of 8 hours ago. 125.5 million tests were done (4.1% positive). 47.6 million were vaccinated (79.0%). +21035 cases, +96 deaths, +565077 tests since a day ago. See https://www.epicentro.iss.it/en/coronavirus/sars-cov-2-dashboard or https://lab24.ilsole24ore.com/coronavirus/en/02:19
de-facto2.6% of cases so thats lowered by an order of magnitude then02:20
LjLyes 2.6% of 8.6% is similar, but that's among all people, many before vaccination was a thing02:20
de-factook fair02:20
LjLinstead in israel they're looking at boosted people vs fully vaccinated people02:20
de-factoyep02:20
LjLso what's the benefit of full vaccinations on those numbers? :\02:21
de-factowe do not know since they did not include a non-vaccinated control group, i guess that is difficult to get nowadays since most are vaccinated or infected already02:26
de-factoanyhow since boosters are for fully vaccinated them using that as control group makes kinda sense to determine the benefit of either receiving a booster or not02:27
lastshelllast CDC comments is booster helps against omicron03:02
de-facto.title https://www.lshtm.ac.uk/newsevents/news/2021/modelling-potential-impact-omicron-england03:05
Brainstormde-facto: From www.lshtm.ac.uk: Modelling the potential impact of Omicron in England | LSHTM03:05
de-facto.title https://cmmid.github.io/topics/covid19/omicron-england.html03:05
Brainstormde-facto: From cmmid.github.io: Modelling the potential consequences of the Omicron SARS-CoV-2 variant in England | CMMID Repository03:05
de-facto.title https://cmmid.github.io/topics/covid19/reports/omicron_england/report_11_dec_2021.pdf03:05
Brainstormde-facto: From cmmid.github.io: Consequences of Omicron03:05
BrainstormNew from BBC Health: Covid booster jabs extended to over-30s from Monday: The move comes as experts say the UK faces a substantial wave of Omicron without further restrictions. → https://www.bbc.co.uk/news/uk-5962175403:06
de-factoLjL,  ^^03:08
LjLand then the ones who got boosters will be the control group of the ones getting the 4th doses... and then the ones with the 4th doses, the 5th...03:10
LjLi'm starting to get a bit eh03:10
LjLit would be nice if we weren't so reliant on data from a country that exchanges data for prioritized access to Pfizer vaccines03:11
LjLi've seen the charts on page 6 on Twitter today03:11
de-factoi meant the uk modeling03:15
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Modelling the potential consequences of the Omicron SARS-CoV-2 variant in England ( https://www.zotero.org/groups/covid_links/items/5MNZWWRU )03:15
BrainstormNew from r/WorldNews: worldnews: Israeli study supports Pfizer findings that booster provides strong protection against omicron → https://old.reddit.com/r/worldnews/comments/reeel1/israeli_study_supports_pfizer_findings_that/03:16
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: CMMID Repository: Covid-19 ( https://www.zotero.org/groups/covid_links/items/SJRCCSD8 )03:20
* enyc meows03:22
enycHrrm, booster with Moderna today, after previous pfizer's03:23
de-factonice congratz03:23
de-factohow is your arm?03:24
enycde-facto: oh just achey03:38
enycnot yet all wiped out, will see!03:39
enycde-facto: curious UK system... seems lots of reports that e.g. booking system allows 30+ to book, and e.g. many walk-in-centres providing booster to 18+ irrespective of govt guidance ......03:41
ZdrytchX.cases australia03:56
BrainstormZdrytchX: Australia has had 228936 confirmed cases (0.9% of all people) and 2104 deaths (0.9% of cases; 1 in 12195 people) as of 2 hours ago. 50.0 million tests were done (0.5% positive). 20.2 million were vaccinated (78.7%). +1557 cases, +4 deaths since 22 hours ago. See https://offloop.net/covid19/?default=Australia&legacy=no03:56
BrainstormZdrytchX: If you know of an official or otherwise good site for data about Australia, with a reasonably short URL, please %tell LjL about it.03:56
de-factowhoa i just got an appointment in a neighboring city at next Friday for Moderna booster03:57
de-factomaybe it was a good idea to check their system in the middle of the night :P03:58
de-factogonna have to drive there for 30 min though, but i am happy i got one timeslot03:59
de-factothey only provide Moderna, BioNTech is reserved for under 30 year olds and pregnant women04:00
de-factowell i dont care both are just fine in my opinion04:00
enycde-facto: yes indeed.. check!04:08
* enyc meows04:15
de-factoenyc, try to avoid anything with high pulse rate for the coming 2 weeks, just some moderate movement (like going for a walk each day) and drink enough :)04:27
de-facto...water of course :P04:27
enycwhatwhatwhat04:28
* enyc ROARs04:28
* enyc used to bicycle and weightlift sessions!04:28
enyc"You should be able to resume activities that are normal for you as long as you feel well. If your arm is particularly sore, you may find heavy lifting difficult. If you feel unwell or very tired you should rest and avoid operating machinery or drivin"04:29
* enyc was all BoUnCiE visiting vaccine centre! all these slow people about and bOuNcIe_enyc runs past... and similarly on way out!04:30
* enyc got accused of believing is still Summer still04:30
de-factoavoid activities with high pulse rates to mitigate the tiny risk of myocarditis even more04:31
* enyc bOuNcIeS all over de-facto 04:32
enycI see04:32
de-factoyeah probably not strictly necessary, but wont hurt, moderate mobility may be beneficial though (to lower thrombosis risk)04:32
de-factoso i am planing to go for a calm walk without high pulse rates every day in the 2 weeks after receiving my booster04:33
BrainstormNew from r/WorldNews: worldnews: FDA says it needs 75 years to release Pfizer COVID-19 vaccine data to the public → https://old.reddit.com/r/worldnews/comments/refo6s/fda_says_it_needs_75_years_to_release_pfizer/04:33
* enyc spanks FDA04:34
de-factoyeah thats just silly :P04:34
de-factoi could just register with EMA and download all the data from their servers for free04:35
de-factothey had PDFs with over 1000 pages iirc04:36
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: CDC: 25 states report omicron strain of COVID-19, but delta remains biggest threat → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/regi0z/cdc_25_states_report_omicron_strain_of_covid19/05:01
BrainstormUpdates for Netherlands: +17760 cases (now 2.9 million) since 20 hours ago05:06
enychrrm05:12
enycnow...  How quickly do PCR tests go negative following infection in a healthy vaccinated, boosted  person ?05:13
enycConsidering the problems for those have gone away cycling etc  and  if catch virus  before travelling home etc05:13
de-factowhy?05:17
LjLterrible people like this are entirely unhelpful to science https://np.reddit.com/r/worldnews/comments/refo6s/fda_says_it_needs_75_years_to_release_pfizer/ho7i63v/?context=305:24
LjLclaiming that something that is being practically forced on *billions* of people should rightfully be kept secret for *business* reasons. such utter bullshit.05:25
BrainstormNew from The Indian Express: World: South African doctors see signs omicron is milder than delta → https://indianexpress.com/article/world/south-african-doctors-see-signs-omicron-is-milder-than-delta-7668537/05:26
LjLif ever i had a reason to be anti-vax, people like that would be the reason05:26
BrainstormUpdates for Venezuela: +774 cases (now 437887), +5 deaths (now 5234) since 23 hours ago — Germany: +32752 cases (now 6.5 million) since 23 hours ago — India: +7774 cases (now 34.7 million), +306 deaths (now 475434) since 23 hours ago05:31
BrainstormNew from The Indian Express: World: Israeli study finds Pfizer Covid-19 booster protects against Omicron → https://indianexpress.com/article/world/israeli-study-finds-pfizer-covid-19-booster-protects-against-omicron-7668554/05:35
xxLjL: there's a difference these days about what "anti-vax" actually means05:38
xx1) anti-vax = against all vaccines cause they are the work of devil or something 2) had taken all the childhood vaccines, maybe even takes the yearly flu vaccine, but is against mandatory vaccines forced by gov onto people who don't need them05:40
xxand maybe some other meanings too05:40
LjLyeah i don't think #2 is very common here per se05:40
LjLvaccinations have been mandatory for decades, so people are either okay with it, or against the whole thing and refusing vaccines05:41
xxI have no data to make a statement on that05:41
LjLso if anything here #3 they took all the things but are skeptical about the COVID one05:41
xxI've heard a good one, but can't find it now. Something about the number of people below 30yo with no comorbidities that definitely died of covid is lower than the number of people who died definitely as the result of the vaccine05:42
xxor maybe people below 20, something like that05:43
xxboth numbers are extremely low anyway, so it is plausible05:43
LjLi would want to know also what the numbers are of people who got long-term complications from the two things05:44
BrainstormNew from The Indian Express: World: COVID: New Zealand man probed for having 10 vaccine shots → https://indianexpress.com/article/world/covid-new-zealand-man-probed-for-having-10-vaccine-shots-7668532/05:44
xxLjL: is there some primary source for that FDA thing?05:45
ublxxx: kinda seems like the sort of thing that's hardly worth saying out loud unless you have some evidentiary reason for believing it to hand imho05:46
LjLnot sure, i've seen the claim before, and i don't think i've seen it challenged, only its significance05:46
* ublx schedules investigation of that for some time other than 5am05:48
ublxnn05:48
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): New preprint led by Kaori Sano in collaboration with @VivianaSimonLab medrxiv.org/content/10.110…. Convalescent individuals induce strong mucosal secretory IgA response after mRNA vaccination. This may help to explain the robust protection from [... want %more?] → https://twitter.com/florian_krammer/status/146989187289836339405:54
BrainstormNew from This Week In Virology: TWiV 841: Unmasking immunity: TWiV provides an update on immunity to Omicron, results of a randomized controlled trial of face masks, and a study of correlates of protection against respiratory syncytial virus infection in the upper and lower respiratory tract of nonhuman primates. → https://www.microbe.tv/twiv/twiv-841/06:13
BrainstormUpdates for Lima, Peru: +5103 cases (now 987590), +136 deaths (now 89096) since 4 days ago — Veneto, Italy: +4062 cases (now 548750), +8 deaths (now 12050) since 23 hours ago — Lombardy, Italy: +4024 cases (now 962239), +21 deaths (now 34566) since 23 hours ago — Quebec, Canada: +3797 cases (now 464227), +4 deaths (now 11607) since 23 hours ago06:33
BrainstormNew from r/COVID19: COVID19: Collapsing passengers, CDC missteps and "public health malpractice": The story of the COVID flight from hell → https://www.reddit.com/r/COVID19/comments/rehyvf/collapsing_passengers_cdc_missteps_and_public/06:41
BrainstormUpdates for United Kingdom: +52430 cases (now 10.8 million) since 23 hours ago07:29
BrainstormNew from r/WorldNews: worldnews: Poll finds 77% of Brits less likely to obey Covid rules after Xmas party scandal → https://old.reddit.com/r/worldnews/comments/reizwh/poll_finds_77_of_brits_less_likely_to_obey_covid/07:46
xxhonestly, if anyone obeyed rules only because they thought the politicians obey them as well, then they are stupid07:47
minthoswow, what a powerful insult07:49
minthoshave you met people?07:50
BrainstormNew from r/COVID19: COVID19: NIH Funding of COVID-19 Research in 2020: a Cross Sectional Study → https://www.reddit.com/r/COVID19/comments/rej7nh/nih_funding_of_covid19_research_in_2020_a_cross/08:23
sdfgsdfgdwhat's poppin08:24
TimvdeCompared to the original Wuhan virus, does omikron have different mutations than the other variants, or does it have all the same ones, and more?09:09
BrainstormNew from r/Coronavirus: Daily Discussion Thread | December 12, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/rekaa9/daily_discussion_thread_december_12_2021/09:09
Timvde(I'm mostly wondering if a vaccine against omicron would also help more than the current vaccines against all the other existing variants, and potential future variants rising from them)09:10
Timvde(Also sorry for writing omikron, it's with a k in Dutch, so it's confusing to switch depending on the language I type in :P)09:11
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): And Sigal estimates protection against omicron by 2xPfizer to be ~40%, and by 3xPfizer to be ~75%. Consistent with Pfizer's estimate.pic.twitter.com/07ZcxVpcXs → https://twitter.com/michaelzlin/status/146994229759687475509:19
BrainstormUpdates for Gujarat, India: +71 cases (now 828077) since a day ago — El Salvador: +2 deaths (now 3795) since 23 hours ago09:33
Dredd<LjL> "vaccine uptake in Portugal is..." <- Implausibly good 🤯10:02
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): This is not-terrible news. The longer we go with a lower CFR for Omicron than past strains, the more assuring it seems.But deaths are not zero either, so there may be a wave of deaths as Omicron spreads thru vaxxed/recovered to find the [... want %more?] → https://twitter.com/michaelzlin/status/146995588019600998710:05
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): That is, the unvaxxed or unboosted will not be shielded from Omicron by those with higher immunity, whereas this was actually becoming true in some places for Delta.So... get vaxxed and boosted if you haven't already. → https://twitter.com/michaelzlin/status/146995617605389926610:15
minthosTimvde: it has some/many of the same mutations as previous ones and many new ones10:18
DreddErrr... all the people saying "omicron seems milder than delta" probably actually mean to say "omicron doesn't seem particularly more severe than delta but it is early days"10:20
minthosit does seem to have different symptoms and so far it hasn't produced a huge wave of hospitalizations and death so there is still cause to be hopeful but it's also too early to conclude10:22
BrainstormNew from BBC Health: Covid booster jabs extended to over-30s from Monday: The move comes as experts say the UK faces a substantial wave of Omicron without further restrictions. → https://www.bbc.co.uk/news/uk-5962175410:24
DreddI'm feeling there's a good chance the UK will have having a lockdown again in the coming weeks10:26
DreddFull on I mean10:26
TimvdeI fear then people would lose all trust in vaccines10:28
minthosTimvde: https://covariants.org/shared-mutations10:30
minthosfound the nice graphical overview I remembered seeing10:30
Timvdeminthos: nice graphic, thanks10:30
Dredd<xx> "honestly, if anyone obeyed rules..." <- Yes, I mean I don't like to use the term "stupid" but it is a fairly apt description of humanity. I prefer "poorly fit to the current environmental conditions" 😛10:32
BrainstormUpdates for Germany: +31516 cases (now 6.5 million) since 19 hours ago10:35
Dredd> Labour leader Sir Keir Starmer said his party would "not be tempted to play party politics" and would back the government in voting for the measures "in the public interest".10:35
DreddOh how nice of him to do his fucking job10:36
DreddThough that didn't seem to be the case a few days back with all the stupid christmas party shit he was pushing that eroded the coverage / awareness of omicron10:36
Dredd> Conservative MP Steve Baker, a lockdown sceptic, told BBC Breakfast he would vote against mandatory vaccinations, Covid passes and extending face covering rules.10:37
DreddEurghhhh10:37
Dredd> He said scientific modelling was "pessimistic", such measures were "disproportionate" and said people needed to learn to live with coronavirus "like we live with flu".10:37
DreddOh yes, because they've been so pessimistic so far10:37
Dredd"If handled badly the UK may have 40k deaths" reality is 150k as of now10:37
DreddThere has been over the top optimism in the government decision makers here10:37
DreddGod damn I hate the stupid political situation here10:38
Dredd</rant>10:38
minthosI can't wait for the day when non-GMO humans are in the minority globally10:41
minthoswe need some serious upgrades10:41
DreddLol, careful or you'll trigger me onto a philosophical rant about the future of humanity 😀10:42
BrainstormUpdates for Libya: +655 cases (now 378105), +13 deaths (now 5553), +4863 tests (now 2.0 million) since a day ago11:00
BrainstormNew from r/WorldNews: worldnews: Almost 2 years later, Anthony Fauci didn't think COVID-19 pandemic would have lasted this long | CBC News → https://old.reddit.com/r/worldnews/comments/reltsq/almost_2_years_later_anthony_fauci_didnt_think/11:11
Guest47If the line on the "T" of a LFT is very feeble, does it still count as positive?11:12
Guest47s/feeble/faint11:12
xxminthos: yes, I've met people. What a bunch of idiots. Best stay away from them.11:21
xxaliens lock their vehicle doors as they pass by earth11:21
minthos:)11:22
xxI wonder what happens in people who are infected with delta and omicron at the same time. Maybe they'll start producing a variant with the virality of omicron and lethality of delta.11:24
xxbest to avoid getting infected in the first place, thus preventing the possibility of a mutation happening11:24
xxinstead of this plan to just vaccinate everyone and open up the place as if there's nothing happening11:25
minthosmy layperson's understanding is that omicron probably outcompetes every other variant in the host11:26
xxI'm slowly getting convinced that it is a bad idea to vaccinate not-vulnerable groups, because it will just lead to more risky behavior in that group, and thus leading to more infections and so higher likelihood of mutations (and especially mutations that go around the vaccinated immune system)11:26
xxminthos: not sure, the data is nonexistent. Almost as nonexistent as last years data on co-infection with flu and covid.11:27
minthosthere was some talk early on about how omicron originated and people speculated that it had time to perfect itself in an immune compromised host over a long period of time, likely with exposure to other variants11:28
xxsadly those are only guesses, we'll never know the actual origin of omicron11:28
Guest47Ok, fuck, day 6 and still testing positive!11:28
xxmy bet would be it simply existed, but was not detected due to lack of sequencing and lack of travel in that group of people11:29
xxGuest47: day 6 from what?11:29
Guest47from day 1 I tested positive11:29
xxand how long ago was the suspected infection?11:29
Guest47who ru asking11:30
xxyou11:30
Guest47How can I possibly know?11:30
xxwell, surely you know who you come into contact with11:30
minthospeople were really surprised at how many new mutations it had, that doesn't just happen overnight (again I'm a layperson so I could be wrong)11:30
Guest47How can I possibly know who infected me?11:30
xxdon't people usually know who infected them?11:31
xxit will be the person with whom you did not follow best practices11:31
Guest47Only in Hollywood movies11:31
* xx does not watch hollywood movies11:31
Guest47xx sure you are confusing covid with aids?11:31
Guest47Nobody follows best practices here11:32
xxI remember the aids epidemic, and the media massage is similar11:32
minthosif you're in a place with a good test & trace system you might have a chance at finding out where it came from but most countries don't11:32
Guest47Because at that time there were none. Social isolation and social distancing were abolished 19 of July I think11:32
Guest47All the people I know have tested negative apart from 2 who refuse to test and vaccinate but you can't force them11:33
xxanyway, you'll test positive for a few more days11:34
Guest47xx how do you know11:34
xxa guesstimate based on 6 days, assuming you got infected ~9 days ago11:34
Guest47where do you get these figures from11:35
xxthe internet11:35
Guest47ah i see11:35
Guest47then it must be true, sorry for doubting11:35
Guest47"the internet" says covid is a hoax11:36
Guest47"the internet" also says that DT won the elections11:36
xxa bit of it is hoax-like, it definitely is not like the plague, and the media likes to make it look worse than it actually is on a population-scale11:37
Guest47oh dear11:37
xxit is bad, but the world is not ending, at least half the population will survive11:37
minthosthere is good and bad information on the internet as everywhere else11:38
BrainstormUpdates for Lesotho: +654 cases (now 23102), +3693 tests (now 273169) since a day ago — Oman: +35 cases (now 304714) since 3 days ago11:38
Guest47no, the internet is only good11:38
corujaas a first reference, look up the site of your national/regional health care service for quite useful information11:39
BrainstormNew from BBC Health: Covid: First people in UK hospitals with Omicron variant: As of Saturday there have been 1,898 confirmed cases of the Omicron coronavirus variant in the UK. → https://www.bbc.co.uk/news/uk-5962718811:39
xxcoruja: ehh11:39
xxI mean, sure, I guess, but they also have lots of wrong info too, and outdated info11:39
minthosimo the best source currently are actual experts on twitter (not just armchair experts like me)11:40
xxsurprisingly, yes11:40
Guest47oh twitter is even better11:40
Guest47there's no manipulated propaganda on Twitter at all11:40
xxI'd take an actual researcher on twitter over a WHO bureaucrat any day11:41
Guest47xx i am not surprised11:41
xxlike, WHO only admitted it is airborne in may *this year*11:41
minthosthere is a torrent of shit on twitter absolutely but you learn to block the morons and follow the heroes11:41
xxsomething that every researcher working with every corona virus before this one already knew decades ago11:41
Guest47of course we know it was manufactured in a Chinese lab to piss orangeman off11:42
xxthe earth is one big lab11:42
xxso yeah, it was made in a lab with poor controls11:42
Guest47of course it must be true because i've seen it on farcebook11:43
xxthe place where nobody checks the fact-checkers11:43
corujai said 'as a first reference', additionally, if one is capable of reading scientific studies (pre-print or peer reviewed), those will be a even better resource of information, or public information spread by serious scientists11:44
Guest47serious scientists only a  few years ago thought that one could cure homosexuality11:44
xxhonestly, anyone with school level of biology education should have already known everything necessary when this was first announced.11:44
Guest47https://psycnet.apa.org/record/1974-30538-00111:45
xxIt's a virus. You protect others by covering your mouth and nose. You protect yourself by washing hands, not touching stuff, keeping away from people, covering your mouth/nose/eyes, ...11:45
xxand eventually it will die off11:45
Guest47Give me any topic and I'll find a serious scientific article that proves or disproves11:45
xxGuest47: fried meat is a human carcinogen11:46
Guest47actually it doesn't die off. People become immune11:46
xxsame thing11:46
Guest47xx evidence?11:46
xxpandemic dying off = people no longer caring about it11:46
minthosGuest47: because some scientists are wrong, all scientists are wrong11:47
Guest47minthos only if another scientist says they are wrong11:47
xxbecause some scientists are funded to spread wrong info, all scientists are paid to spread wrong info11:47
Guest47oh dear11:47
xxwii Guest4711:48
BrainstormNew from r/WorldNews: worldnews: COVID-19: Omicron cases being treated in hospital, cabinet minister Nadhim Zahawi tells Sky News | Politics News → https://old.reddit.com/r/worldnews/comments/remewc/covid19_omicron_cases_being_treated_in_hospital/11:48
Guest47Ok so following this logic, I should stop self isolating 10 days after symptoms have started. So If I still test positive at the 10th day, can I end self isolation?11:51
Guest47or would that reset the clock?11:51
minthosthat's not how it works11:52
minthosI don't know how long people stay infectious but I personally would self-isolate until I test negative11:52
minthosit could be quick or it could take weeks11:52
minthosusually quick-ish11:52
Guest476 days seem a lot of me, considering i haven't had symptoms for 3 days11:53
minthossymptoms can return11:54
Guest47fuck i hope not11:54
minthosit's not the norm, you'll probably be fine soon11:54
Guest47sorry guys i am paranoid, depressive and anxious by myself, the infection is not helping11:56
minthosyeah pandemics suck, I think we're all feeling it11:57
Guest47Goiing out for a walk every day is what has prevented me from taking my life (yet)11:57
xxminthos: unless you have pfizer stock, then this has been the best thing ever11:57
Guest47xx how old are you11:57
xxor any other relevant stock11:57
minthoswalks are great, I do that too11:58
Guest47because if you're over 12 we have a problem here11:58
xxGuest47: too old, probably only have less than 10 years to live, already older than my parents and grandparents were when they died of old age11:58
Guest47ok so your just being cynical then11:59
TimvdeGuest47: where I live, it's 10 days or 3 days after your last symptoms, whichever takes longer11:59
xxGuest47: you haven't been in this channel long :)11:59
xxget a registered account11:59
xxI discriminate against Guest** nicks :p11:59
Guest47Timvde where exactly11:59
TimvdeBelgium11:59
Guest47xx deal with it12:00
xxTimvde: 10 days since first positive test presumably?12:00
Timvdexx: yes12:00
Guest47Timvde nederlands ou francais (of tussentaal)?12:00
TimvdeDutch12:00
Guest47bon12:00
minthosget your daily dose of sardonic misanthropy here12:01
xxI was wondering last year about whether the 10 day was based on actual data12:01
xxfelt like it should have been 14 days for good measure12:01
xxespecially if the person is free to go without any negative test to confirm12:01
Guest47It used to be 14 days at the beginning12:01
xxGuest47: some countries had 1012:01
TimvdeGuest47: I heard that you could still test positive at least on the self tests for a couple of months due to some residue, but I don't know how much of that is true12:02
xxthat was with PCR tests12:02
xxuntil they tweaked the parameters or something12:02
xxbecause viral fragments remain for a long time and do replicate under PCR too12:02
BrainstormUpdates for Nepal: +242 cases (now 824222), +1 deaths (now 11554), +6268 tests (now 4.7 million) since a day ago12:03
Guest47Ok so we have two people in the household who refuse to vaxx/test and because of that we can't ask for a PCR test or we all have to leave the place and become homeless (long story but true)12:03
Guest47at the same time we can't kick them out just because they refuse to get tested, so they win12:03
xxrefuse to vaxx, ok whatever, but refuse to test?12:03
Guest47yes12:03
xxthat sucks12:03
Guest47Well they are the "it's just a hoax" crowd12:04
Guest47At least they are consistent12:04
minthosand here I am getting annoyed at bad drivers12:04
xxbad drivers are the worst, I should know because I am one of them12:05
Guest47THis is the problem here in UK. Rules are too bland and not even enforceable.12:05
xxnobody followed anything in UK after the initial few days when the cities were actually empty on webcams12:05
xxthe pandemic has essentially been over in the mind of the public since then12:06
Guest47The moment the police try to slap a fine on someone for not wering a mask, they will call their MP who will complain about racism, discrimination, etc.12:06
Guest47xx the govt being a bunch of pricks didn't help12:07
xxthey've always been pricks12:07
TimvdeOur government isn't a bunch of pricks, yet people are not listening to them anymore12:07
Guest47I have a anti vaxx woman saying to me: "what about my human right to infect other people"12:07
xxTimvde: I don't believe you12:07
xxbelgium gov has been pricks for years too12:08
Timvdexx: Well, let's say it differently12:08
TimvdeThe *biggest* pricks aren't in there12:08
xxI can accept that :)12:08
xxI don't think there has been a gov anywhere that handled this well. But again, this pandemic is all about personal responsibility anyway, so no gov can help.12:09
TimvdeNZ?12:09
xxTimvde: NZ has been a joke. Thanks to various factors is died off there, the gov said it was all thanks to the gov, relaxed everything and now it's back and worse than ever.12:09
xxi.e. everything good that happens is thanks to the gov, everything bad that happens is not the fault of the gov12:10
TimvdeI haven't been following recently, although I heard that with delta they couldn't keep it out anymore12:10
TimvdeLet me check the numbers12:10
TimvdeTotal numbers less than what we have per day, that seems pretty good12:10
xxyeah but look at the graphs12:11
minthosGuest47: tell her that right stands on equal footing with the government's right to put her in prison12:11
xxand *all* of that could have been prevented, if they had implemented mandatory testing on entry12:12
xxbut they didn't want to12:12
Guest47minthos no i just told her to fuck off. You can't argue with stupid, and unfortunately the government cannot send her to prison12:12
minthosthat's too bad, they should12:12
minthosknowningly infecting other people with a deadly disease is considered assault in many places12:13
minthosor attempted murder or w/e12:13
Guest47minthos you can argue she doesn't know because she doesn't get tested12:13
xxminthos: works that way only for some diseases12:13
xxknowlingly giving someone the sniffles will not land you in prison12:14
xxaids won't do that anymore either apparently12:14
xx(in canada)12:14
Guest47do humans share dna with canadians?12:15
minthosyes12:15
minthosalso with chimpanzees12:15
xxI'm on the fence12:15
Guest47i don't mind chimpanzees but that bublè....12:16
xxminthos: please don't share your dna with chimps, they most likely can't consent12:16
BrainstormNew from Politico: British politics: Boris Johnson faces fresh criticism over lockdown Christmas quiz → https://www.politico.eu/article/boris-johnson-uk-criticism-christmas-quiz-coronavirus-lockdown/12:16
minthosok I won't12:16
minthosit's not like they are lining up outside my bedroom door anyway12:17
* xx would be very scared if there were chimps lining outside the bedroom door12:18
xxchimps catch the rona too12:18
xxare they getting vaccinated yet?12:18
minthosmaybe they line up outside people's bedrooms to get vaccinated12:19
xxthey probably would be injected with something else than the vaccine then...12:20
Guest47Fact: chimps don't develop cancer12:20
Guest47or gorillas? One of the two12:20
xxGuest47: that's because we eat them before they reach that age where cancer is prevalent12:20
Guest47xx who eats chimps?12:21
xxprimates12:21
Guest47do humans eat chimps? I mean humans, not canadians12:22
xxalternatively I could have said "Of course chimps don't develop cancer, it's developed in Chinese labs to destroy USA"12:22
xxGuest47: yeah, chimps are edible12:22
xxnothing about them is poisonous, all organs are fine unlike other animals12:23
Guest47xx have you?12:23
Guest47Where do i buy chimp meat12:23
xxit's dangerous though, you might grow a liking to primate meat...12:24
xxand it's a downward spiral to trying out all the other primates...12:24
Guest47cannibalism was quite common once12:25
Guest47you have to season the meat though12:25
darsieAlthough some scientists equate humans with all members of the genus Homo, in common usage it generally refers to Homo sapiens, the only extant member.12:26
xxyou don't *have to*12:26
xxdarsie: we need a new homo12:27
darsieLooks like chimps are neither humans nor homos.12:27
Guest47Okla homo12:27
Guest47That's a pity. Looks like chimps are not LGBT friendly.12:28
xxI don't think chimps discriminate, they'll eat any face12:29
xxso yeah, humans and chimps are the the group of 'hominids'12:29
Guest47err no chimps are not hominids12:30
xxchimps are not great apes?12:31
xx(true, there's nothing great about them, unless you consider that they are really good at eating faces)12:31
darsieI'm taller.12:31
minthosThe gorilla, chimpanzee, bonobo, and orangutan are called great apes in recognition of their comparatively large size and humanlike features; the gibbons are called lesser apes.12:32
minthos(britannica.com)12:32
Guest47ok sorry i confused with hominins12:32
xxwell, unless wiki is wrong, hominids = organgutan, gorilla, chimp, human12:32
xxheh, organgutan, it guts organs12:33
BrainstormUpdates for UAE: +83 cases (now 742802), +278933 tests (now 104.7 million) since a day ago12:34
xxGuest47: hominins are humans and chimps12:34
darsieThe name "orangutan" (also written orang-utan, orang utan, orangutang, and ourang-outang[1]) is derived from the Malay words orang, meaning "person", and hutan, meaning "forest".[2][3] The locals originally used the name to refer to actual forest-dwelling human beings, but the word underwent a semantic extension to include apes of the Pongo genus at an early stage in the history of Malay.[2][4]12:35
xxand I thought it was because of their orange color12:35
BrainstormNew from r/Science: science: Japanese scientists create vaccine for aging to eliminate aged cells, reversing artery stiffening, frailty, and diabetes in normal and accelerated aging mice → https://old.reddit.com/r/science/comments/ren6cc/japanese_scientists_create_vaccine_for_aging_to/12:35
xxwhat a time to be a mouse12:36
darsieYou could be a drosophila, c. elegans or e. coli, if you prefer.12:37
xxI still believe that the solution to avoiding extinction of orangutans is to start breeding them for scientific experiments instead of mice12:38
darsieScientific model organsims often have a very small gene pool.12:39
darsieWe should stop growing oil palms.12:39
xxbut palm oil is more useful than a living orangutan12:41
xxso I doubt we'll stop doing it any time soon12:41
xxagain, the solution would be to find a use for orangutans, preferably something very profitable12:42
darsieAnd not trust WWF white washing seals.12:42
darsieLike growing cattle, pigs and chicken?12:43
xxgo #vegan I guess12:43
darsieI remember a case of a female orangutan sex slave.12:43
xxlol what?12:43
darsieI remember a case of a female orangutan sex slave.12:43
xxwell, I guess that could be a solution too12:44
xxbut it would probably interfere with the highly profitable human sex slave business12:44
darsie##vegan it is.12:45
lastshellbetween been vegan or have sex with a femlae orangutan mm tough call12:46
Dredd<xx> "don't people usually know who..." <- Not always, as with anything12:46
xxnow this has to be some bullshit https://worldnewsdailyreport.com/indonesia-zoo-keeper-accused-of-impregnating-female-orangutan/12:46
xxorangutans and humans are DNA compatible?12:46
darsiehttps://en.wikipedia.org/wiki/Roundtable_on_Sustainable_Palm_Oil#Criticisms12:47
xxso not only corona-compatible?12:47
lastshell90-ish something12:47
darsieSpecies are usually defined by not being able to produce fertile offspring wiht other species.12:47
xxDredd: that's why I said usually :)12:47
darsieLarge cats somewhat don't fit in that definition.12:48
xxdarsie: oh wow, so it could have offspring, but the offspring would not be fertile?12:48
darsieyes, like mules12:48
xxthat's horrifying, there are actual human-nothuman hybrids out there?12:48
darsieI don't think so.12:48
xxI probably voted for some, now that I think about it12:48
lastshellhttps://www.thedonkeysanctuary.org.uk/what-we-do/knowledge-and-advice/about-donkeys/mules-and-hinnies some sort of can12:49
xxmules are a known thing, but that orangutan-human is horrifying12:49
darsieIt's not a thing.12:49
darsieIf it was, human rights and stuff would be interesting.12:50
Dredd<xx> "get a registered account" <- I'm sure if they want to they will, no need to tell people what they need to do 🙂12:50
darsieThere have been efforts to grant human rights to gorillas.12:50
xxDredd: true12:51
xxthere have also been efforts to remove human rights from humans12:51
darsieAnyone annoyed by this thread?12:51
xxI can somewhat symphatise, nobody should have some special rights just because they were born a man, or a woman, or a human12:51
darsieWell, USA didn't sign "human rights".12:52
xxI don't remember signing anything either12:52
darsieLike, the right to live ...12:52
xxright to live only because you have some specific DNA? Sounds "racist" to me.12:53
darsiespecist?12:53
xxsome sort of -ist, yeah12:53
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Samenvattend; er zijn een enorme barrières die voorkomen dat RNA, na vaccinatie of virus infectie, ook maar in de buurt van ons DNA kan komen. Zelfs al zou dat onmogelijke gebeuren is er niets aan de hand en ruimt ons immuunsysteem zo´n cel op! RNA vaccines [... want %more?] → https://twitter.com/Marc_Veld/status/146999726732308480512:54
Guest47They say homo sapiens is the only human left, but what about the jedwards?12:54
Guest47https://en.wikipedia.org/wiki/Jedward12:54
Guest47you no telling me this is homo sapiens?12:55
xxis there a list of species that can catch this corona, and a separate list of species where it can successfully replicate and spread to others?12:56
darsiespeciest*12:56
xxis it simply all mammals?12:56
Guest47mammals mia!12:59
Guest47I'd be curious to know if the virus responsible for the Spanish flu is actuall still in circulation13:00
xxvery likely not, viruses don't have that sort of stability, it would have mutated into something similar but not the same by now if it hadn't died out13:01
Guest47https://www.bbc.com/future/article/20181120-what-if-a-deadly-influenza-pandemic-broke-out-today13:01
xxwell, we know exactly what would happen if it broke out *today*, nobody would care because of course it's a hoax13:02
xxI vividly remember the videos of people falling on the streets, ridden with the rona, used to scare everyone13:02
BrainstormNew from COVID on Twitter: Covid Fact Check UK (@fact_covid): This is not currently on the table, but would you *refuse* to go to a pub or restaurant if you were required to show either proof of a negative lateral flow test or vaccination status to gain entry? → https://twitter.com/fact_covid/status/146999867220948992213:03
xxpubs and restaurants will probably transform into something where people only go for very special occasions13:05
xxlike a few times per life13:06
Guest47People will still go to bars and restaurants unless you completely shut them. Plenty of clubbing action in the area last night.13:08
BrainstormNew from COVID on Twitter: Covid Fact Check UK (@fact_covid): This is a well-considered article by @BallouxFrancois on Omicron and the challenges it poses to governments nearly two years into the pandemic. It could have long-lasting implications, whether it proves to be especially rough or mild.theguardian.com/commentisfree/… → https://twitter.com/fact_covid/status/147000204065494221013:12
minthosour vaccine and hygiene game will catch up eventually13:15
minthosindoor air quality is terrible in many buildings, filtering air and blasting UVC into ventilation shafts isn't on the radar for most people but it can help a lot13:16
minthosthe prevailing medical ortodoxy was that anything bigger than 5 microns wasn't "airborne" because bigger droplets get stuck in the nose and don't reach the lungs where turberculosis infects people, even though droplets as big as 100 microns can be considered "airborne" in the context of viruses like corona13:17
xxthe failure in report is that it was reported as "It's not airborne = you can't catch it through air"13:18
minthosit IS airborne and you CAN catch it through air, but the medical definition of airborne is wrong, based on a misunderstanding from over half a century ag13:19
minthoso13:20
minthosso people insisted it wasn't airborne because it didn't meet the medical definition of airborne or some bullshit like that13:20
BrainstormUpdates for Bangladesh: +329 cases (now 1.6 million), +6 deaths (now 28028), +21612 tests (now 11.1 million) since 23 hours ago — Qatar: +166 cases (now 245354), +1 deaths (now 613), +5304 tests (now 3.1 million) since 15 hours ago — Germany: +32210 cases (now 6.5 million) since 22 hours ago13:36
BrainstormNew from Contagion Live: Booster Dose Reduced COVID-19 Across Adult Age Groups in Israel: A booster dose of the m-RNA vaccine reduced COVID-19 and the rates of severe illness across adult age groups. → https://www.contagionlive.com/view/booster-dose-reduced-covid-19-across-adult-age-groups-in-israel13:40
BrainstormNew from The Indian Express: World: UK opens up Covid boosters to all over 30s in Omicron fight → https://indianexpress.com/article/world/uk-opens-up-covid-boosters-to-all-over-30s-in-omicron-fight-7669261/14:27
xxminthos: you and me both know it, but the WHO has probably killed hundreds of thousands by saying "corona isn't airborne"14:36
BrainstormUpdates for Netherlands: +52 cases (now 2.9 million) since 21 hours ago14:38
minthosyes14:54
squirrelhttps://twitter.com/disclosetv/status/146998352810018816014:59
squirrelis this real life15:00
darsie.tw 146998352810018816015:04
BrainstormNew from StatNews: Biotech: STAT+: Roche two-armed antibody posts strong tumor responses in lymphoma study, rivaling CAR-T therapy → https://www.statnews.com/2021/12/12/roche-two-armed-antibody-posts-strong-tumor-responses-in-lymphoma-study-rivaling-car-t-therapy/15:05
minthosthat's as german as it gets but I don't think it'll be enough to stop the virus15:06
BrainstormUpdates for United Kingdom: +52381 cases (now 10.8 million) since 22 hours ago15:40
BrainstormNew from Reddit (test): China_Flu: Effects of Weight Loss on Adipose and Muscular Neuropilin 1 mRNA Expression in Obesity: Potential Implication in SARS-CoV-2 Infections? - FullText - Obesity Facts → https://old.reddit.com/r/China_Flu/comments/repwwm/effects_of_weight_loss_on_adipose_and_muscular/15:42
BrainstormNew from r/WorldNews: worldnews: Japanese scientists develop vaccine to eliminate cells behind aging → https://old.reddit.com/r/worldnews/comments/req515/japanese_scientists_develop_vaccine_to_eliminate/15:52
BrainstormNew from r/WorldNews: worldnews: Austria ends lockdown restrictions ONLY for vaccinated people — the unvaccinated must stay at home and are subject to nationwide vaccine mandates, with fines for those who don't comply → https://old.reddit.com/r/worldnews/comments/reqijb/austria_ends_lockdown_restrictions_only_for/16:10
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): UK confirmed Omicron cases nearly doubled since yesterday with some leading to the first hospitalizations there ft.com/content/56079e… pic.twitter.com/v9vlHOVb9p → https://twitter.com/EricTopol/status/147005129094838681716:29
BrainstormUpdates for Denmark: +6028 cases (now 560477), +9 deaths (now 3027) since 23 hours ago16:30
BrainstormNew from r/WorldNews: worldnews: Global shortage of nurses set to grow as pandemic enters third year, says group → https://old.reddit.com/r/worldnews/comments/rerb2f/global_shortage_of_nurses_set_to_grow_as_pandemic/16:48
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Denmark, where Omicron is heading towards dominance in a matter of days, on top of its recent Delta surge @OurWorldInData sst.dk/en/english/cor… pic.twitter.com/FuYTwgOlxH → https://twitter.com/EricTopol/status/147005872445458432216:57
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Just a reminder: even if Omicron is less severe; it can certainly do harm. Get your vaccines, which is now 3 shots and will protect very well against severe disease.BBC News - Covid: First people in UK hospitals with Omicron variantbbc.co.uk/news/uk-596271… → https://twitter.com/Marc_Veld/status/147006907419772519017:35
BrainstormUpdates for Netherlands: +16614 cases (now 2.9 million), +38 deaths (now 20568) since 18 hours ago17:39
BrainstormUpdates for Italy: +19212 cases (now 5.2 million), +66 deaths (now 134831), +501815 tests (now 126.0 million) since 23 hours ago18:03
BrainstormNew from The Indian Express: World: Austria ends lockdown restrictions for vaccinated people → https://indianexpress.com/article/world/austria-ends-lockdown-restrictions-for-vaccinated-people-7669438/18:12
BrainstormNew from Politico: Coronavirus: UK raises coronavirus alert level over Omicron threat → https://www.politico.eu/article/health-officials-issue-omicron-warning/18:59
BrainstormNew from r/WorldNews: worldnews: Austria ends Covid lockdown restrictions ONLY for vaccinated people → https://old.reddit.com/r/worldnews/comments/reu85p/austria_ends_covid_lockdown_restrictions_only_for/19:08
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Without a booster vs Omicron, the vaccine effectiveness early point estimate for Pfizer was 35% vs symptomatic infection assets.publishing.service.gov.uk/government/upl…twitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/147009498464887193919:17
BrainstormUpdates for United Kingdom: +48173 cases (now 10.9 million), +52 deaths (now 146896) since 23 hours ago — Faroe Is.: +97 cases (now 4372), +7000 tests (now 598000) since a day ago19:30
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This is holding up a couple of days later. The longer we go w/ very small % hospitalizations, especially if seen in older people, no prior Covid, unvaccinated, the more likely it'll be the immunity wall + something intrinsic to the virus to explain less virulence (<-hope) → https://twitter.com/EricTopol/status/147010076665219072219:45
BrainstormNew from r/WorldNews: worldnews: 'Three shots of Pfizer COVID vaccine 4x less effective against Omicron' → https://old.reddit.com/r/worldnews/comments/rev9pp/three_shots_of_pfizer_covid_vaccine_4x_less/19:55
LjL4x less effective than what19:56
LjLsilly headlines19:56
LjL(4x less neutralizing ability than with Delta, is the answer)19:56
LjLand also "Dr. Sharon Alroy-Preis says country could recommend boosters as early as three months after second shot" - who was it that was asking about whether i knew anything concrete about places recommending as little as 3 months before boosters19:57
TimvdeThe EMA said the same thing iirc20:21
LjLTimvde, there are a few relevant instances of "3 months" in my logs, but funnily enough (actually it's what always happens in these cases) i cannot find the instance where someone inquired about it20:22
LjL"Those who received the second dose did not have any neutralization ability against the variant, while they continued to have some ability against Delta and even the original Wuhan strain."20:30
LjL"even"? how incompetent can an article get20:31
LjLthe vaccine *is* against the original Wuhan strain20:31
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy → https://www.reddit.com/r/COVID19/comments/rew1ob/sarscov2_infection_of_the_central_nervous_system/20:32
de-facto.title https://jamanetwork.com/journals/jama/fullarticle/278699220:51
Brainstormde-facto: From jamanetwork.com: Immunogenicity of Extended mRNA SARS-CoV-2 Vaccine Dosing Intervals | Vaccination | JAMA | JAMA Network20:51
de-factoas usual the longer dosing interval was superior, unfortunately the PDF is behind a paywall20:53
de-facto"For the first investigation, the mean age for the short (dosing interval range, 18-28 days) group was 39 years (43% women); 70% received BNT162b2 and 30%, mRNA-1273; for the medium (range, 42-49 days) group, the mean age was 41 years (47% women); 60% received BNT162b2 and 40%, mRNA-1273."20:57
de-facto"Comparing immunogenicity based on time after the second vaccine dose (matched at mean, 56 days [SD, 26 days]), the viral neutralization geometric mean was 54.6 (GSD, 3.0) for the short group vs 230.8 (GSD, 2.0) for the medium group (P < .001)."20:58
de-facto"The spike antibody concentrations measured using the monoplex assay for the short group were 1697 U/mL (GSD, 1.7 U/mL) vs 2476 U/mL (GSD, 1.0 U/mL) for the medium group (P < .001). The ACE-2 inhibition for the Beta variant was 11.2 U/mL (GSD, 1.6 U/mL) for the short group vs 14.7 U/mL (GSD, 1.8 U/mL) for the medium group (P = .04)."20:58
de-facto"See Figure 1 for the Delta variant results. The comparisons of the Wuhan, Alpha, and Gamma variants were not statistically significant."20:58
de-factothe figures can be seen under their tab "Figures/Tables"20:58
de-facto"For the second investigation, the mean age was 41 years (60% women), 87% received BNT162b2 and 13%, mRNA-1273, for both the short (range, 21-36 days) and long (range, 102-118 days) groups."20:58
de-facto"Comparing immunogenicity based on time after the first vaccine dose (mean days, 179 [SD, 4.0 days] for the short group and 180 days [SD, 5.7 days] for the long group), the viral neutralization geometric mean was 41.8 (GSD, 2.8) for the short group vs 302.3 (GSD, 2.4) for the long group (P < .001)."20:59
de-facto"For the short vs long groups, the geometric mean monoplex spike antibodies were 928.4 U/mL (GSD, 2.1 U/mL) vs 1154 U/mL (GSD, 5.0 U/mL; P = .002). The geometric means for ACE-2 inhibition for the Alpha variant were 7.7 U/mL (GSD, 1.7 U/mL) vs 22.8 U/mL (GSD, 2.3 U/mL; P < .001); for the Beta variant, 5.4 U/mL (GSD, 3.1 U/mL) vs 15.5 U/mL (GSD, 2.0 U/mL; P < .001), and for the Gamma variant, 4.9 U/mL (GSD, 1.5U/mL) vs 14.3 U/m20:59
de-factoL (GSD, 2.1 U/mL; all P < .001). "!20:59
de-facto"Results for the Wuhan and Delta variants are presented in Figure 2."20:59
LjLholy WoT20:59
BrainstormUpdates for Togo: +28 cases (now 26400), +2360 tests (now 592231) since 2 days ago21:04
JigsyBoris Johnson: "Get boosted now."21:08
JigsyYeah, you can fuck off until New Year.21:08
* Jigsy won't really be going anywhere for the next three weeks or so anyway.21:09
JigsyNot really in the mood to feel like shit before then, anyway.21:09
JigsyBut by the time January rolls around it won't matter because January is shit wall-to-wall anyway.21:09
LjLJigsy, i barely felt anything after my boost21:10
JigsyMy Dad was ill for a week.21:10
LjLof course that doesn't necessarily mean you will not feel anything21:10
JigsyFelt like he had been hit by a bus.21:10
LjLi wonder how much better COVID feels21:11
JigsyMy Aunt was the same.21:11
LjLwe should be able to see Omicron causing a spike in the UK sometimes this coming week... which is probably why he's pushing to get boosted21:11
de-facto.title https://www.lshtm.ac.uk/newsevents/news/2021/modelling-potential-impact-omicron-england21:12
Brainstormde-facto: From www.lshtm.ac.uk: Modelling the potential impact of Omicron in England | LSHTM21:12
de-factoJigsy, this may be the reason for preparing for impact21:13
JigsyI would have preferred another lockdown, to be honest.21:13
JigsySimply because I hate other people.21:13
Jigsy:D21:13
LjLmaybe i should add that article to Zotero, since i added the modelling paper itself but it's a bit hard to grok21:14
LjLa nice thing on Zotero is you can "link" two entries together as "related"21:15
LjLso sometimes i included the tweets that lead me to papers in the "Comments" folder while linking them to the paper in question21:15
LjLa less nice thing is i haven't figured out how to do that from the webapp, so i have to run the actual desktop app to do that, while for other things, the webapp works better :P21:16
de-factoyeah Zotero indeed is quite neat21:19
BrainstormNew from BBC Health: Covid: New booster target as Boris Johnson declares Omicron 'emergency': There is a tidal wave of Omicron coming, says Boris Johnson, as boosters are offered to all over-18s in England. → https://www.bbc.co.uk/news/uk-5963157021:19
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Modelling the potential impact of Omicron in England ( https://www.zotero.org/groups/covid_links/items/GKSSKRNX )21:20
ArsaneritI also barely felt anything after my boost.21:20
LjLit's likely that those who had no reactions on the second shot will be the same with the boosters, and unfortunately those who did have reactions after the second shots will probably have them with the booster too21:21
BrainstormNew from Politico: Coronavirus: Boris Johnson warns of Omicron ‘tidal wave’ as he vows faster booster jabs → https://www.politico.eu/article/boris-johnson-warns-of-omicron-tidal-wave-as-he-vows-faster-booster-jabs/21:28
BrainstormUpdates for South Africa: +37875 cases (now 3.2 million), +21 deaths (now 90137), +62414 tests (now 20.2 million) since a day ago — France: +43848 cases (now 8.4 million), +48 deaths (now 121416) since 23 hours ago — Canada: +256 cases (now 1.8 million) since 22 hours ago21:29
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): In Norway, roll-out in kids under 11 is not even decided upon; parents in Norway presently have been given no option to vaccinate their 5-11 year olds. I ask the same: Where's the sense of urgency? twitter.com/laineydoyle/st… → https://twitter.com/GANyborg/status/147012911835641447721:38
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): While boosters should not be the only course of action, they are 1 thing we can do to help against Omicron easily & quickly in countries where available.Why are we sticking to "6 months" in #Switzerland when we could go much faster?? [... want %more?] → https://twitter.com/firefoxx66/status/147013233808442982921:47
BrainstormNew from r/WorldNews: worldnews: South African president has COVID-19, symptoms mild → https://old.reddit.com/r/worldnews/comments/rexxoi/south_african_president_has_covid19_symptoms_mild/22:06
BrainstormUpdates for United Kingdom: +48159 cases (now 10.9 million) since 23 hours ago22:31
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): If you think Prior Covid protects against Omicron (B.1.1.529), think again medrxiv.org/content/10.110…and"Neutralizing antibody titers against Omicron were low, even below the limit of detection in a significant fraction of convalescent [... want %more?] → https://twitter.com/EricTopol/status/147014570546544230722:44
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Reinfection from Omicron in people who had Covid—UK"Preliminary analyses indicate approximately 3-8 fold increased risk of reinfection with the Omicron variant" assets.publishing.service.gov.uk/government/upl…—South Africa >2.4-fold [... want %more?] → https://twitter.com/EricTopol/status/147014852161341030622:53
BrainstormUpdates for India: +3632 cases (now 34.7 million) since 17 hours ago — Kuwait: +39 cases (now 413711), +21685 tests (now 5.6 million) since 23 hours ago23:08
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): Twitter "experts": "hey guys omicron is super mild don't worry about it"Also Twitter "experts": "get a 3rd dose to protect yourself against omicron"Twitter experts inevitably when no one gets their 3rd dose: pic.twitter.com/GMb6lfwTk2 → https://twitter.com/JT_Grindrod/status/147015379255325081623:12
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): This is after months of telling people that 2 doses are plenty and if you get a 3rd shot you're selfishly depriving the rest of the world.The only thing that was deprived of a vaccine because of your 3rd shot was a dumpster. → https://twitter.com/JT_Grindrod/status/147015631877840896523:21
LjLHhhmff23:30
LjLWhy's that been retweeded and by whom23:30
LjLThat RSS (actually Atom) thing is... well... good, or at least I don't know of anything else that can get a feed from Twitter reliably. But the fact you can't distinguish from direct tweets and retweets is not great23:32
de-factonot sure if that is even possible in groups, maybe you would need one tweet per name23:40
BrainstormNew from Virological.org: Latest topics: Omicron is a Multiply Recombinant Set of Variants That Have Evolved Over Many Months:  William R. Gallaher Mockingbird Nature Research Group, Pearl River, LA 70452 and Dept. of Microbiology, Immunology and Parasitology, [... want %more?] → https://virological.org/t/omicron-is-a-multiply-recombinant-set-of-variants-that-have-evolved-over-many-months/77523:40

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