| Brainstorm | Updates for Malaysia: +24316 cases, +64 deaths since 22 hours ago — Samoa: +375 cases since 2 days ago | 00:00 |
|---|---|---|
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): New @UKHSA preprint by @juliastowetoffa and colleagues on booster vaccine effectiveness vs Omicron wave vs hospitalizations: high protection out to 4 months in 65+ age group khub.net/documents/1359… pic.twitter.com/uLiz10Gpyt → https://twitter.com/EricTopol/status/1507136824635846679 | 00:32 |
| Brainstorm | New from The Lancet (Online): [Comment] Strengthening public mental health during and after the acute phase of the COVID-19 pandemic: The evolving nature of the COVID-19 pandemic with its incumbent stresses and the emergence of highly transmissible SARS-CoV-2 variants continue to challenge [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00523-2/fulltext | 00:41 |
| Brainstorm | New from r/COVID19: COVID19: Mice infected with Mycobacterium tuberculosis are resistant to acute disease caused by secondary infection with SARS-CoV-2 → https://old.reddit.com/r/COVID19/comments/tn8mel/mice_infected_with_mycobacterium_tuberculosis_are/ | 01:01 |
| Brainstorm | Updates for Canada: +8790 cases, +84 deaths since 22 hours ago | 01:03 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Just realized this ironic evolution of talking points by prominent vax defenders:7/2021: What breakthrough infections? Our vaccines are perfect. Anybody saying there are breakthroughs is anti-vax.3/2022: Of course vax don't prevent infections. [... want %more?] → https://twitter.com/michaelzlin/status/1507149472211513346 | 01:20 |
| Brainstorm | Updates for Australia: +61109 cases, +32 deaths since 23 hours ago — Slovakia: +11296 cases since 23 hours ago — Germany: +92915 cases, +44 deaths since 8 hours ago | 01:59 |
| Brainstorm | Updates for United Kingdom: +3768 cases, +1 deaths since 8 hours ago — Cayman Is.: +96 cases, +3 deaths since 8 days ago | 04:04 |
| Brainstorm | New from Reddit (test): Covid2019: Can Moderna actually make a vaccine for the common cold? (And should it?) – Moderna said in a brief statement that it would start developing a single vaccine against the four coronaviruses that have long infected humans → https://old.reddit.com/r/Covid2019/comments/tnct7x/can_moderna_actually_make_a_vaccine_for_the/ | 04:21 |
| LjL | yes please | 04:39 |
| oerheks | that would be epic, common cold | 05:13 |
| Brainstorm | New from Science-Based Medicine: COVID and Our Warped Sense of Normal: Children are not supposed to die. This didn't used to be controversial. The post first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/warped/ | 05:46 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Bloomberg: ‘Hong Kong’s leader has deflected blame for the city’s failure to get elderly vaccinated.’“There are a lot of forces at work to prevent the government from doing what should be done,” Carrie Lam said. “In this case [... want %more?] → https://twitter.com/ScottGottliebMD/status/1507230976178630670 | 06:43 |
| Brainstorm | New from MedicineNet: (news): Moderna Will Ask FDA to Approve COVID Vaccine for Young Kids → http://www.medicinenet.com/script/main/art.asp | 07:02 |
| Brainstorm | Updates for Western Australia, Australia: +16655 cases, +9 deaths since 2 days ago — Selangor, Malaysia: +11692 cases, +8 deaths since 23 hours ago — Guernsey, United Kingdom: +2936 cases since 8 days ago — Miyagi, Japan: +699 cases since 23 hours ago | 07:06 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | March 25, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/tng7oz/daily_discussion_thread_march_25_2022/ | 08:08 |
| Brainstorm | Updates for Taiwan: +136 cases, +40333 tests since a day ago | 09:05 |
| Brainstorm | New from r/Science: science: Around 90% of deceased people tested at a Lusaka facility during coronavirus surges were positive for SARS-CoV-2 infection, suggesting flaws in the idea of an ‘African paradox’. → https://old.reddit.com/r/science/comments/tngdzf/around_90_of_deceased_people_tested_at_a_lusaka/ | 09:14 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 25MAR22 → https://old.reddit.com/r/nCoV/comments/tnh68p/global_covid_cases_for_25mar22/ | 09:24 |
| Brainstorm | New from StatNews: Opinion: How we got herd immunity wrong: The idea that vaccinating a certain percentage of the population would stop transmission of SARS-CoV-2 was a seductive but unhelpful description of herd immunity. → https://www.statnews.com/2022/03/25/how-we-got-herd-immunity-wrong/ | 09:43 |
| Brainstorm | Updates for Israel: +13408 cases, +5 deaths since 22 hours ago | 10:02 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: En Garde For SARS-CoV-2 Chimeras (Recombinants): Recombinants may also appear not only by coinfection in humans, but infection in the large reservoir of animal populations SARS-CoV-2 is capable of infecting, namely [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/tnhueo/en_garde_for_sarscov2_chimeras_recombinants/ | 10:12 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Almost 2 in 5 Covid-19 researchers have faced harassment, survey finds → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/tniihx/almost_2_in_5_covid19_researchers_have_faced/ | 11:01 |
| Brainstorm | New from r/COVID19: COVID19: Persistent Overactive Cytotoxic Immune Response in a Spanish Cohort of Individuals With Long-COVID: Identification of Diagnostic Biomarkers → https://old.reddit.com/r/COVID19/comments/tnixbr/persistent_overactive_cytotoxic_immune_response/ | 11:30 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), elasomeran,COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, Revision: 20, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax | 11:50 |
| Brainstorm | New from ScienceNews: How I’ll decide when it’s time to ditch my mask: New COVID-19 masking guidelines are designed for communities not individuals, making a decision about safety difficult. → https://www.sciencenews.org/article/covid-coronavirus-mask-guidelines-community-risk | 12:10 |
| Brainstorm | New from BBC Health: Covid: Wales' mask law to end in shops, but not NHS: Despite rising cases, the law to self-isolate if you have Covid will end on Monday. → https://www.bbc.co.uk/news/uk-wales-politics-60863358 | 12:38 |
| peetaur | politics is so dumb... ending masks and ending walking around with a contagious virus is completely different...why do they end around the same time? | 13:09 |
| xx | because democracy, dumb people elect dumb politicians | 13:21 |
| xx | the coronavirus pandemic is a great example of failures of democracy | 13:21 |
| Brainstorm | New from Novavax: (news): Novavax Announces Participation in Two Booster Studies Using its COVID-19 Vaccine → https://ir.novavax.com/2022-03-25-Novavax-Announces-Participation-in-Two-Booster-Studies-Using-its-COVID-19-Vaccine | 13:37 |
| Brainstorm | New from BBC Health: UK Covid infections climb by a million in a week: Around 4.3 million people - or one in every 16 - are thought to have the virus, compared to 3.3 million the week before. → https://www.bbc.co.uk/news/health-60872687 | 13:47 |
| Brainstorm | Updates for Malta: +465 cases, +1 deaths since 22 hours ago | 14:00 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: Pharma hunts for a cure for long Covid; Texas AG deepens puberty-blocker probe into AbbVie and Endo → https://www.statnews.com/pharmalot/2022/03/25/covid19-patents-puberty-generic-hiv/ | 14:26 |
| Brainstorm | Updates for Vanuatu: +259 cases since a day ago | 15:03 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: German health minister: no 'freedom day' from COVID yet: "Hospitals in particular were having to cancel procedures due to large numbers of sick staff" → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/tnm2hm/german_health_minister_no_freedom_day_from_covid/ | 15:06 |
| Brainstorm | New from NPR Science: COVID and schizophrenia: Why this deadly mix can deepen understanding of the brain: People with schizophrenia are three times as likely to die from the virus, giving scientists an opportunity to study the potential relationship between the immune system and mental illness. → https://www.npr.org/sections/health-shots/2022/03/25/1088058422/covid-and-schizophrenia | 15:25 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): First assessment of 4th dose in Israel beyond 12+ days in 60+ age group (vs 3 doses, Omicron). Effectiveness vs infection drops faster than 3rd dose but added protection vs severe illness holds up > 2 months medrxiv.org/content/10.110… pic.twitter.com/oki4r3J4gQ → https://twitter.com/EricTopol/status/1507367126910201857 | 15:44 |
| Brainstorm | New from COVID on Twitter: Florian Krammer (@florian_krammer): New pre-clinical data with a trivalent, variant-targeting NDV-HXP-S vaccine. Wild type+Beta+Delta result in immunity to Omicron. biorxiv.org/content/10.110… → https://twitter.com/florian_krammer/status/1507369120945393665 | 15:54 |
| Brainstorm | Updates for Canada: +12003 cases, +97 deaths, +78499 tests since 23 hours ago | 15:59 |
| Brainstorm | New from Contagion Live: Risk of COVID-19 Breakthrough Infection Heightened for Immunocompromised: People with immune dysfunction are at increased risk for COVID-19 breakthrough infection after vaccination, and should take additional precautions. → https://www.contagionlive.com/view/risk-of-covid-19-breakthrough-infection-heightened-for-immunocompromised | 16:23 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): @CellCellPress An Omicron-specific vaccine provided no benefit compared with a mRNA booster (vs ancestral) in the macaque model with immunologic response and lung protection assessmentcell.com/cell/fulltext/… pic.twitter.com/HPWQAKYIyQ → https://twitter.com/EricTopol/status/1507378863050944512 | 16:33 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): UKHSA preprint.Highlighting why the booster is required against Omicron!khub.net/documents/1359… pic.twitter.com/cyb7ZI2mBw → https://twitter.com/Marc_Veld/status/1507381605052129304 | 16:43 |
| ublx | White House: "The most common way COVID-19 is transmitted from one person to another is through tiny airborne particles of the virus hanging in indoor air for minutes or hours after an infected person has been there. While there are various strategies for avoiding breathing that air – from remote work to masking – we can and should talk more about how to make indoor environments safer by | 16:48 |
| ublx | filtering or cleaning air." | 16:48 |
| ublx | ^ https://www.whitehouse.gov/ostp/news-updates/2022/03/23/lets-clear-the-air-on-covid/ | 16:48 |
| ublx | haven't been tracking officialdom's stance on primacy of the airborne factor, but this departure from the US CDC's own output seems striking | 16:49 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Amazing how the media can sometimes talk nonsense with anonymous sources! @news24 you can do better than that, why not talk to the network of genomics surveillance in SA before putting this piece out ? Devastating Delta variant back on SA's radar… [... want %more?] → https://twitter.com/Tuliodna/status/1507384360793747462 | 16:53 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): and an interesting new graph estimating the number of people saved from hospital with the help of vaccines! This is why the vaccine effort was so important! pic.twitter.com/HGhR6S77Vk → https://twitter.com/Marc_Veld/status/1507384722057535493 | 17:03 |
| Brainstorm | Updates for Germany: +188819 cases, +206 deaths since 15 hours ago | 17:08 |
| Brainstorm | New from LitCovid: (news): A Systematic Review of the Global Intervention for SARS-CoV-2 Combating: From Drugs Repurposing to Molnupiravir Approval. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/35321497 | 17:22 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Derek Tshiabuila having fun and proving hands on training in SARS-CoV-2 to Ethiopian Bioinformaticians Migbani Keffale and Bethlehem Getaneh. Together, making Africa advance genomics surveillance. @RickABright @RockefellerFdn @AfricaCDC @WHOAFRO [... want %more?] → https://twitter.com/Tuliodna/status/1507393846950436877 | 17:32 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The UK BA.2 situation is worsening ft.com/content/03beea…"If you think naively England is going to top out very soon, Scotland shows otherwise . . . the numbers are insanely high and still growing.” --@BristOliver with his graphs pic.twitter.com/ZsStLwOpxo → https://twitter.com/EricTopol/status/1507399172802052100 | 17:51 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): EMA recommends authorisation of COVID-19 medicine Evusheldtwo monoclonal antibodies designed to attach to the spike protein of the SARS-CoV-2 virusema.europa.eu/en/news/ema-re… → https://twitter.com/Marc_Veld/status/1507399556874612749 | 18:01 |
| Brainstorm | Updates for Spain: +72892 cases, +339 deaths since 3 days ago | 18:04 |
| Brainstorm | New from The Atlantic: ‘Their Priority Is Just to Flee and Survive’: There is no good time for a war, but there are certainly bad ones. Even as Russia’s full-scale invasion of Ukraine enters its second month and the civilian death toll nears 1,000 , the pandemic churns on. In [... want %more?] → https://www.theatlantic.com/health/archive/2022/03/ukraine-crisis-pandemic-outbreak/629379/ | 18:11 |
| LjL | ublx: when nothing else is left to do... | 18:40 |
| LjL | But worry not, they'll ensure it'll soon seem like everybody had always been saying so | 18:40 |
| LjL | %cases uk | 18:45 |
| Brainstorm | LjL: United Kingdom has had 20.8 million confirmed cases (31.3% of all people) and 164874 deaths (0.8% of cases; 1 in 403 people) as of 13 hours ago. 499.9 million tests were done (7.5 per capita, 4.2% positive). 51.8 million were vaccinated (78.0%). +3768 cases, +1 deaths since 8 hours ago. See https://coronavirus.data.gov.uk/ | 18:45 |
| oerheks | %cases nl | 18:46 |
| Brainstorm | oerheks: Netherlands has had 7.9 million confirmed cases (45.1% of all people) and 22486 deaths (0.3% of cases; 1 in 776 people) as of 42 minutes ago. 29.9 million tests were done (1.7 per capita, 26.3% positive). 13.3 million were vaccinated (76.3%). +34989 cases, +20 deaths since 13 hours ago. See https://coronadashboard.government.nl/ | 18:46 |
| oerheks | much less testing than UK | 18:47 |
| LjL | Most countries have less testing than the UK | 18:47 |
| LjL | Still mindblowing prevalence | 18:48 |
| oerheks | i did not notice that before, thanks! | 18:48 |
| oerheks | 1st bumblebee inside my house, 2022 https://photos.app.goo.gl/sJaLnuEtmeZwAfA96 | 18:48 |
| Brainstorm | New from CIDRAP: COVID-19 Scan for Mar 25, 2022: Delta, Omicron and pregnancy Variant-specific long COVID → https://www.cidrap.umn.edu/news-perspective/2022/03/covid-19-scan-mar-25-2022 | 18:49 |
| LjL | Weather is a bit too warm isn't it | 18:52 |
| ublx | LjL: i saw actual dead tree print newspaper (the ipaper - an offshoot of The Independent) here say that hospitalisations in recent days in scotland are the worst they have yet been during pandemic | 18:58 |
| LjL | I saw that too (elsewhere) | 18:59 |
| LjL | Not sure it's different in England except for either numbers being fuzzed up or people no longer being hospitalized despite being sick enough | 18:59 |
| LjL | How am I supposed to believe any of the numbers anymore when it's obvious there has been a concerted effort by many countries to change the reporting | 19:00 |
| LjL | Although I can't say which countries exactly did the thing, because I was distracted by a war nobody can make any sense of | 19:00 |
| LjL | But I saw enough to see there were patterns | 19:01 |
| LjL | No more PCR unless you're at risk even if LFT is positive | 19:01 |
| LjL | Death definitions changed to "only if they die within n days of symptoms" (UK was early on that one) | 19:02 |
| LjL | Expressed wish to stop counting covid deaths separately from other respiratory diseases, even | 19:02 |
| LjL | For myself I'm most concerned about the dropping of indoor mask mandate at the end of April because I'm pretty sure I will curtail my going anywhere at all in response | 19:03 |
| LjL | Not that much will change | 19:03 |
| ublx | about the UK high quality testing - i stopped daily downloads of numbers idk a month or so ago amidst the concerted gov and business efforts to drive relaxation of restrictions and testing | 19:03 |
| ublx | couldn't imagine numbers being meaningful anymore | 19:04 |
| LjL | And yet, even then, the official numbers are pretty high | 19:04 |
| LjL | It's just nobody cares | 19:04 |
| ublx | can't remember precisely, could have been two or three months ago now | 19:04 |
| Brainstorm | Updates for Japan: +47015 cases, +115 deaths since 12 hours ago — Canada: +83 deaths since 21 hours ago | 19:07 |
| LjL | I thought Japan was going down | 19:07 |
| LjL | I'm still baffled by the stark divergence of otherwise similar Japan and Korea | 19:08 |
| Brainstorm | Updates for United Kingdom: +80471 cases, +175 deaths since 21 hours ago | 20:10 |
| Brainstorm | New from r/Coronavirus: Coronavirus: UK Covid infections climb by a million in a week → https://old.reddit.com/r/Coronavirus/comments/tntro8/uk_covid_infections_climb_by_a_million_in_a_week/ | 20:25 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Update of genomics and epidemiological surveillance in South Africa. - Infection is low (around 1,000 a day) with positivity of around 5%- Hospitalization is low with severe cases at ICU of 200- Omicron BA.2 dominates (> 95%) pic.twitter.com/X8NPkMWL13 → https://twitter.com/Tuliodna/status/1507438084186685442 | 20:34 |
| Brainstorm | New from CIDRAP: COVID-19 vaccines not tied to adverse pregnancy outcomes: Mary Van Beusekom | News Writer | CIDRAP News Mar 25, 2022 One study author calls the results reassuring and hopes they increase vaccine uptake. → https://www.cidrap.umn.edu/news-perspective/2022/03/covid-19-vaccines-not-tied-adverse-pregnancy-outcomes | 20:44 |
| Brainstorm | Updates for Italy: +76397 cases, +146 deaths, +503973 tests since a day ago | 21:00 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): There's debated about how much of an Omicron BA.2 wave the US will experience. But no debate how ill-prepared with respect to vaccinations and boostersft.com/content/f55aa9… by @mroliverbarnes @jburnmurdoch @labboudles @JamieSmythF pic.twitter.com/z5iMjpeuIe → https://twitter.com/EricTopol/status/1507446306444251139 | 21:03 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: AIM Vaccine: LVRNA009 → https://covid19.trackvaccines.org/vaccines/189/ | 21:13 |
| Brainstorm | New from COVID19 Vaccine Tracker: (translated) valerie: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/ | 21:32 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Airlangga University: UNAIR Inactivated COVID-19 Vaccine → https://covid19.trackvaccines.org/vaccines/181/ | 21:42 |
| Brainstorm | New from CIDRAP: Reported TB cases drop in US amid COVID-19: Stephanie Soucheray | News Reporter | CIDRAP News Mar 25, 2022 Also, the elderly, Black Americans, and those with less education were less likely to use free at-home COVID-19 tests. → https://www.cidrap.umn.edu/news-perspective/2022/03/reported-tb-cases-drop-us-amid-covid-19 | 21:51 |
| Brainstorm | Updates for France: +143619 cases, +121 deaths since 23 hours ago — Papua New Guinea: +1543 cases, +1 deaths since 17 days ago — Tonga: +335 cases since a day ago | 22:02 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): The BA.2 Omicron sub-variant represented 59% of samples collected on March 17th according to the latest data from scientists at @my_helix via @alexbolze public.tableau.com/app/profile/he… pic.twitter.com/WEFTbwbK0p → https://twitter.com/ScottGottliebMD/status/1507464772589178884 | 22:20 |
| arschus | I'm getting mixed instructions and all those instructions conflict with what I do even though I asked for them. | 22:30 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The rapid rise of rapid antigen tests in the United States, the reasons for their use, and the exacerbation of Covid inequities cdc.gov/mmwr/volumes/7… @CDCMMWR pic.twitter.com/bDvayM2hfa → https://twitter.com/EricTopol/status/1507467357177798657 | 22:30 |
| arschus | What do I do? What do I do about the loopback adapter? What do I do about Azure? | 22:30 |
| arschus | [Something about free will, self determination, and the philosophical implications here.] | 22:31 |
| Brainstorm | New from COVID on Twitter: Kristian G. Andersen (@K_G_Andersen): Quick on the rising SARS-CoV-2 wastewater signal in San Diego.Data:searchcovid.info/dashboards/omi…searchcovid.info/dashboards/was… pic.twitter.com/6ON8nVVeFf → https://twitter.com/K_G_Andersen/status/1507473558074580995 | 22:50 |
| Brainstorm | Updates for Germany: +276746 cases, +300 deaths since 20 hours ago | 22:59 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The results aren't all bad; antibodies are made. But neutralizing Ab (NAb) levels at peak (3wk after dose 2) are below human convalescent sera (HCS), at 154 vs 281 IU/mL. How does this compare vs. other vax? Similar to original "1-dose" J&J [... want %more?] → https://twitter.com/michaelzlin/status/1507476510017404928 | 23:00 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Icosavax had confidence based on animal data that their vaccine would do a lot better than HCS: "the level of response was below our expectations given what we know... from our own clinical data". And Novavax with the same vax format did manage to [... want %more?] → https://twitter.com/michaelzlin/status/1507478880164073474 | 23:09 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The VLP has multiple RBD copies (it's multivalent), which should activate B cell receptor (BCR) on naive B cells better than free RBD. BCR contains the initial transmembrane form of antibodies; dimerization sends the first signal to activate the B [... want %more?] → https://twitter.com/michaelzlin/status/1507481572475211780 | 23:18 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The VLP has multiple RBD copies (it's multivalent), which should activate B cell receptor (BCR) on naive B cells better than free RBD. BCR contains the initial transmembrane form of antibodies; clustering sends the first signal to activate the B cell. [... want %more?] → https://twitter.com/michaelzlin/status/1507482440960393220 | 23:28 |
| Brainstorm | New from StatNews: Officials limit an antibody therapy, saying it’s ineffective against BA.2 variant of Omicron: U.S. health officials on Friday stopped the further deployment of the Covid-19 treatment sotrovimab to places where the BA.2 coronavirus variant is now causing the [... want %more?] → https://www.statnews.com/2022/03/25/fda-limits-therapy-ineffective-against-ba2-variant-omicron/ | 23:38 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Both Novavax and Icosavax also use an adjuvant to stimulate an immune response. In Novavax it's a plant saponin (soapy molecule) called Matrix M. Icosovax appears to be using the oil-water emulsion MF59. Today's news confirms the adjuvant is [... want %more?] → https://twitter.com/michaelzlin/status/1507488507920470019 | 23:47 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): So the differences come down to (Icosavax / Novavax):1. RBD / full-length uncleavable spike2. Uniform and firm all-protein / non-uniform and mushy protein-lipid particles3. MF59 adjuvant / Matrix M adjuvant4. 5, 25, or 125 ug (micrograms) / 5 ug → https://twitter.com/michaelzlin/status/1507490773054283776 | 23:57 |
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