libera/##covid-19/ Thursday, 2022-03-24

LjLAmong all the participants regardless of previous infection within 7 days to 2 months after receipt of the third dose, 6 cases were observed in the vaccine group and 110 cases in the placebo group, for a relative vaccine efficacy of 94.7% (95% CI, 88.2 to 98.1). In the analyses performed through the data-cutoff date, Covid-19 was identified in 7 participants in the vaccine group and in 124 in the placebo group, for a relative vaccine efficacy of 94.6% (95% CI,00:01
LjL88.5 to 97.9).00:01
LjLso not really any different00:01
LjLthis is hard to believe though00:03
LjLthis is 95% efficacy *on top of* whatever efficacy the original two shots had00:03
LjLjust on being positive, not hospitalizations or anything00:03
LjLam i just misremembering delta?00:03
JigsyMom's saying today marks 2y since COVID started.00:04
JigsyWhich would be believable if it wasn't for the fact it isn't.00:04
LjLuh, i suppose it might for some specific area00:06
LjLbeen more than two years in me lands00:06
JigsyI base it on the first reported case, which was like December 2019.00:09
JigsyOh, man, it was November?00:10
JigsyI thought it was December.00:10
LjLi think it was originally December, then earlier ones were reconstructed00:14
LjLi think i learned about it on december 2900:14
xxdoes *everyone* get some (even tiny) *permanent* brain damage if they get infected with covid?00:15
LjLpossible00:17
LjL%title https://www.nature.com/articles/s41586-022-04569-500:18
BrainstormLjL: From www.nature.com: SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature00:18
LjL"Importantly, these imaging and cognitive longitudinal effects were still seen after excluding the 15 cases who had been hospitalised."00:18
BrainstormNew from ##covid-19 Zotero group: Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine: Type Journal Article Author Edson D. Moreira Author Nicholas Kitchin Author Xia Xu Author Samuel S. Dychter Author Stephen Lockhart Author Alejandra Gurtman Author John L. Perez Author Cristiano Zerbini Author Michael [... want %more?] → https://www.zotero.org/groups/covid_links/items/NSNM2MCS00:23
LjLThe deficits were of substantial effect size for people who had been hospitalised (N = 192), but also for non-hospitalised cases who had biological confirmation of COVID-19 infection (N = 326). https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00324-2/fulltext00:24
xxdo you think the group of humans that never had covid will turn the others into effectively slaves or lesser humans to be used for menial lebor instead?00:27
xxs/lebor/labor00:27
xxfor example, if the brain damage is permanent, I'd never hire someone who had covid before and instead would hire someone who never had covid00:28
xxand those who had covid would instead get trivial tasks to do for little money00:28
BrainstormNew from The Lancet (Online): [Comment] Financing the future of WHO: WHO has anchored the global health architecture since its founding in 1948, and it is impossible to imagine another institution filling the void if the international community were to let it atrophy. While also confronting [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00533-5/fulltext00:33
LjLnow i regret trying to answer the question00:40
xxI doubt I'm the first one asking that question00:42
BrainstormUpdates for Malaysia: +22491 cases, +65 deaths since a day ago01:01
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): The 3rd shor resulted in a relative vaccine efficacy of 95.3% (95% confidence interval, 89.5 to 98.3). pic.twitter.com/kkd6roCDig → https://twitter.com/Marc_Veld/status/150678499896741478501:11
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Neutralization Profile after Recovery from SARS-CoV-2 Omicron InfectionOmicron BA.1 without prior infection or vax;  no cross-reactivity of neutralising antibodies to other VoCs. But omicron after vax results in a good crossreactivity.nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/150678668492666880601:21
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Why is the vaccine important? It causes a broad antibody response. Spike us enginered to be in an open conformation so it easier raises neutralising antibodies. Not all bind each VoC, but each infection will select for those that are a best fit.science.org/doi/10.1126/sc… → https://twitter.com/Marc_Veld/status/150678836940940083201:30
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Moderna to ask FDA to authorize Covid-19 vaccine in children 6 months to 6 yearsBut efficacy against symptomatic disease is around 40%. statnews.com/2022/03/23/mod… → https://twitter.com/Marc_Veld/status/150679230738275123401:40
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): In a prospective cohort of over 1,000 people with moderate to critical Covid, the memory T cell response  at 1 year across variants was well preserved, indicative of sustained protection vs severe disease thelancet.com/journals/lanmi… @LancetMicrobe pic.twitter.com/E7hGJZJJLU → https://twitter.com/EricTopol/status/150679439773988045201:50
BrainstormUpdates for Slovakia: +12192 cases since 13 hours ago — Cook Is.: +112 cases, +371 tests since 11 hours ago02:04
LjL%cases slovakia02:30
BrainstormLjL: Slovakia has had 2.4 million confirmed cases (43.6% of all people) and 19185 deaths (0.8% of cases; 1 in 284 people) as of 25 minutes ago. 6.8 million tests were done (1.2 per capita, 35.2% positive). 2.7 million were vaccinated (49.9%). +12192 cases since 13 hours ago. See https://korona.gov.sk/en/02:30
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Consistent with protection prior to Omicron in very large Denmark study at 1 yeartwitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/150680614433699020902:38
BrainstormUpdates for United Kingdom: +103286 cases since 22 hours ago03:00
BrainstormNew from r/COVID19: COVID19: Association of COVID-19 with risks of hospitalization and mortality from other disorders post-infection: A study of the UK Biobank → https://old.reddit.com/r/COVID19/comments/tlsrhj/association_of_covid19_with_risks_of/03:26
LjLSevere COVID-19 was also associated with increased all-cause mortality (HR=14.700, 95% CI: 13.835-15.619). Mild (non-hospitalized) COVID-19 was associated with modestly increased risk of all-cause mortality (HR=1.237, 95% CI 1.037-1.476) and mortality from neurocognitive disorders (HR=9.100, 95% CI: 5.590-14.816), as well as hospital admission from a few disorders such as aspiration pneumonitis, musculoskeletal pain and other general signs/symptoms.03:54
LjLholy. shit.03:54
LjLhttps://www.medrxiv.org/content/10.1101/2022.03.23.22272811v103:54
LjLnote that 9.1x neurocognitive disorders in MILD covid03:55
LjLthey had a 600 day followup03:55
LjL(at best, presumably)03:55
ublx:|03:56
* ublx partakes of some neuroregenerative sleep03:57
LjLthis is insane03:58
LjLwe can't just... accept that we're going to be at 10x the disk of dying from dementia03:58
LjL"in the best case"03:58
BrainstormNew from ##covid-19 Zotero group: Association of COVID-19 with risks of hospitalization and mortality from other disorders post-infection: A study of the UK Biobank: Type Report Author Yong Xiang Author Ruoyu Zhang Author Jinghong Qiu Author Hon-Cheong So URL [... want %more?] → https://www.zotero.org/groups/covid_links/items/SHVWPECF04:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Corrected link for the large Denmark study, showing the drop pin protection vs Omicronpapers.ssrn.com/sol3/papers.cf… → https://twitter.com/EricTopol/status/150682993358622310504:14
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: It Was Already Hard to Find Evusheld, a Covid Prevention Therapy. Now It’s Even Harder. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/tlwvg9/it_was_already_hard_to_find_evusheld_a_covid/04:52
LjLfirst time i hear of it04:53
BrainstormNew from Reddit (test): Covid2019: S.3726 - CARE for Long COVID Act → https://old.reddit.com/r/Covid2019/comments/tlwzpr/s3726_care_for_long_covid_act/05:01
BrainstormNew from This Week In Virology: TWiV 879: Indolent, resistant, and losing our TMPRSS: TWiV reviews the emergence of remdesivir-resistant SARS-CoV-2 during treatment of a persistently infected immunocompromised patient, and how altered TMPRSS2 utilization by the Omicron variant influences infectivity and fusion. → https://www.microbe.tv/twiv/twiv-879/05:11
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Ministerial Advisory Committee (MAC) advisories for SA Health minister now open access! Transparency is so important and happy to see these available at:  sacoronavirus.co.za/category/mac-a… → https://twitter.com/Tuliodna/status/150685180225963212805:40
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): We are already producing 100s of TB genomes to understand transmission and drug resistance and setting up RNAseq for helping to understand pre clinical TB. Please count on us to fight the #TB pandemic ! twitter.com/lindagailbekke… → https://twitter.com/Tuliodna/status/150686883557144576806:47
BrainstormUpdates for South Australia, Australia: +10396 cases, +4 deaths since a day ago — Selangor, Malaysia: +10240 cases, +12 deaths since a day ago — Jilin, China: +1810 cases since a day ago — Akita, Japan: +286 cases since a day ago07:11
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 24, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/tlzx7f/daily_discussion_thread_march_24_2022/08:03
Micha55:-)08:42
BrainstormUpdates for Taiwan: +139 cases, +33216 tests since 23 hours ago09:04
BrainstormNew from WHO Euro: Tuberculosis remains one of the deadliest infectious diseases worldwide, warns new report: According to the latest European Centre for Disease Prevention and [... want %more?] → https://www.euro.who.int/en/media-centre/sections/press-releases/2022/whoeurope-and-ecdc-joint-press-release-tuberculosis-remains-one-of-the-deadliest-infectious-diseases-worldwide,-warns-new-report09:19
BrainstormNew from StatNews: NIH’s identity crisis: The pandemic and the search for a new leader leave the agency at a crossroads: Francis Collins’ popularity masked a debate raging in university labs and biotech boardrooms over whether the NIH is living up to its mission — or what its mission should be. → https://www.statnews.com/2022/03/24/nih-identity-crisis/09:38
BrainstormUpdates for Tonga: +753 cases, +13563 tests since a day ago — France: +16 deaths since 12 hours ago10:06
BrainstormNew from NPR Science: Evidence grows that vaccines lower the risk of getting long COVID: Though findings are preliminary, many studies suggest that vaccinated people have good protection against the condition, although just how much is still up for debate. → https://www.npr.org/sections/health-shots/2022/03/24/1088270403/long-covid-vaccines10:07
BrainstormNew from BMJ: Is the UK's covid inquiry at risk of forgetting about children and young people?: Almost the only thing that people seem to agree on about the SARS-CoV-2 pandemic and its management is that we need to learn lessons for future crises. As such, in the UK, there are high expectations... → http://www.bmj.com/content/376/bmj.o785.short10:55
BrainstormNew from BMJ: It is not too late to achieve global covid-19 vaccine equity: During the covid-19 pandemic, we have seen the best of international collective action and its limits. Global scientific cooperation drove the development of safe, highly effective covid-19 vaccines... → http://www.bmj.com/content/376/bmj-2022-070650.short11:43
BrainstormNew from Pfizer: Anonymous: Pfizer Granted FDA Breakthrough Therapy Designation for Respiratory Syncytial Virus Vaccine Candidate for the Prevention of RSV in Older Adults → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-granted-fda-breakthrough-therapy-designation-011:52
BrainstormUpdates for Vanuatu: +331 cases since 22 hours ago11:59
BrainstormNew from COVID on Twitter: Jeffrey Barrett (@jcbarret): This resonated with something I've been thinking but couldn't articulate. Gov'ts have switched to a vaccines-only strategy, which is a risky bet no matter what. But even worse is if it fails, we've put ourselves in a position where the only backstop is lockdown, [... want %more?] → https://twitter.com/jcbarret/status/150694718233897369812:02
BrainstormNew from ECDC: ECDC: 14-day notification rate weighted by vaccine uptake, updated 24 March 2022 → https://www.ecdc.europa.eu/en/publications-data/combined-indicator-week-11-202212:11
BrainstormUpdates for Canada: +5012 cases since 15 hours ago13:02
BrainstormNew from Reddit (test): 24/03/22 - ZOE COVID-19 Study Update: 3,734,316 people are currently predicted to have symptomatic COVID-19 in the UK, up by 133,752. Yesterday was 3,600,564 (+4%) and last Thursday was 2,807,072 (+33%). → https://old.reddit.com/r/CoronavirusUK/comments/tm4b2k/240322_zoe_covid19_study_update/13:19
BrainstormNew from Contagion Live: Pfizer Receives FDA Breakthrough Therapy Designation for its RSV Vaccine: This designation of the company’s respiratory syncytial virus (RSV) vaccine candidate, PF-06928316, will help to expedite its development and review. → https://www.contagionlive.com/view/pfizer-receives-fda-breakthrough-therapy-designation-for-its-rsv-vaccine13:58
BrainstormUpdates for Laos: +2819 cases since 22 hours ago14:04
BrainstormNew from COVID on Twitter: Nick Loman (@pathogenomenick): @kallmemeg @jcbarret @chrischirp At the moment getting treatments seems not great because you have to go LFT pos -> PCR pos -> treatment and it's too slow. Not sure future plan? → https://twitter.com/pathogenomenick/status/150697732306473779314:07
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: FDA rejects Lilly drug studied only in China; AstraZeneca suffers a setback with a key cancer drug → https://www.statnews.com/pharmalot/2022/03/24/fda-lilly-astrazeneca-cancer-nitrosamine-nih-merck/14:27
BrainstormNew from r/COVID19: COVID19: Viral load dynamics of SARS-CoV-2 Delta and Omicron variants following multiple vaccine doses and previous infection → https://old.reddit.com/r/COVID19/comments/tmbakq/viral_load_dynamics_of_sarscov2_delta_and_omicron/15:06
BrainstormNew from COVID on Twitter: Paul Mainwood (@PaulMainwood): Really valuable stuff from @UKHSA: new VE vs hospitalisation analysis in their vaccine surveillance report.Roughly:Column 1 = effectiveness against admissionColumn 2 = effectiveness against 2 day admission for respiratory illnessColumn 3 = Col 2 + [... want %more?] → https://twitter.com/PaulMainwood/status/150700112821876326415:36
BrainstormUpdates for Bhutan: +659 cases, +3092 tests since a day ago — Canada: +5695 cases, +20 deaths since 19 hours ago16:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): No difference BA.1 vs BA.2 seen for VE vs hospitalization;  both fall ~20 per cent points after 70 days pic.twitter.com/QtcDvY3Vkd → https://twitter.com/EricTopol/status/150700914150351258316:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Nearly 200,000 Covid hospitalizations are estimated to have been prevented by boosters, age 25+, since mid-December pic.twitter.com/T4TEtenhFE → https://twitter.com/EricTopol/status/150701012217786368116:15
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Keep in mind the UK booster rate is 2-times the US and 2-dose vaccine protection vs Omicron hospitalization (BA.1 or BA.2) is poor (VE 30-50% after waning) without a booster pic.twitter.com/CVhLcAEVCm → https://twitter.com/EricTopol/status/150701351514750157116:25
BrainstormNew from ClinicalTrials.gov: (news): Characterization and Modulation of Brain Networks to Promote Brain Resilience for the Coronavirus (COVID-19) Pandemic → https://clinicaltrials.gov/ct2/show/NCT0529343116:35
BrainstormNew from ClinicalTrials.gov: (news): Incidence of Colonization by Multidrug-resistant Organisms in Mechanically Ventilated Patients With Severe COVID-19 → https://clinicaltrials.gov/ct2/show/NCT0529341816:54
BrainstormUpdates for Germany: +330043 cases, +323 deaths since 23 hours ago17:00
BrainstormNew from ClinicalTrials.gov: (news): Endourological Management of Stones During COVID19 → https://clinicaltrials.gov/ct2/show/NCT0529326217:25
jokoonI've read that a vaccine for the omicron strain was in the test phase... any info about this vaccine getting approved?17:30
BrainstormNew from ClinicalTrials.gov: (news): Cognitive Impact in Patients With COVID-19 Infection → https://clinicaltrials.gov/ct2/show/NCT0529356117:34
BrainstormNew from CIDRAP: News Scan for Mar 24, 2022: NFL games and COVID-19 county spread PCR Strep tests and antibiotic use → https://www.cidrap.umn.edu/news-perspective/2022/03/news-scan-mar-24-202217:44
BrainstormNew from COVID on Twitter: Prof. Shane Crotty (@profshanecrotty): High quality Tfh COVID-19 work from the Juno and Kent labs. Really well done. nature.com/articles/s4159… → https://twitter.com/profshanecrotty/status/150703876591874050018:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The Omicron BA1.1 lineage was the predominant one in the US, now out-competed by BA.2. It has only one key spike mutation different than BA.1 (R346K), whereas BA.2 has many and is more transmissible outbreak.info pic.twitter.com/3vU8eMgzSM → https://twitter.com/EricTopol/status/150704330460030976318:23
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Here's the updated genomic surveillance @CDCgov data covid.cdc.gov/covid-data-tra…57% BA1.135% BA.2 pic.twitter.com/AVsryNiERy → https://twitter.com/EricTopol/status/150704597561693798618:33
BrainstormNew from COVID on Twitter: Janine Kimpel (@JanineKimpel): Infection with BA.1 omicron alone does not induce high titers of neutralizing antibodies to pre-omicron variants. #GetVaccinatedNow@NEJM  nejm.org/doi/full/10.10… Thanks to @AnnikaRoessler @knabl_l @DorotheeLaer @imed_tweets twitter.com/AnnikaRoessler… → https://twitter.com/JanineKimpel/status/150705013449178318618:53
BrainstormUpdates for Japan: +49550 cases, +126 deaths since 21 hours ago — Italy: +82648 cases, +182 deaths, +545302 tests since 23 hours ago18:59
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Just published @ScienceMagazine Pinpointing precisely how monoclonal antibodies do or don't work to neutralize Omicron with structural biologyscience.org/doi/10.1126/sc… pic.twitter.com/Abhp4MU4Or → https://twitter.com/EricTopol/status/150705661258165865319:13
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): What a day! Our Omicron paper comes in print in Nature (looking great due to @houzhou amazing figures!), got an award for helping people in SA (tip no real money but so proud to help people) and this great paper come at MBE on Selection analysis of Omicron [... want %more?] → https://twitter.com/Tuliodna/status/150705909063111066219:23
BrainstormNew from StatNews: Listen: Helen Branswell on the evolving pandemic, plus the next FDA debate and the perks of being a CEO: Are Covid-19 vaccines a sustainable business? Was Aduhelm an aberration? And what comes after Omicron? Find out on the latest episode of "The Readout LOUD." Listen now: → https://www.statnews.com/2022/03/24/podcast-evolving-pandemic-fda-debate-ceo-perks/19:42
BrainstormUpdates for United Kingdom: +97920 cases, +159 deaths since 20 hours ago20:02
LjLwhat is deltacron again?20:43
BrainstormNew from CIDRAP: Prone position might not work for awake COVID-19 patients: Lisa Schnirring | News Editor | CIDRAP News Mar 24, 2022 Patients were able to tolerate only about 2.5 hours per day in the position. → https://www.cidrap.umn.edu/news-perspective/2022/03/prone-position-might-not-work-awake-covid-19-patients20:51
BrainstormUpdates for Canada: +5742 cases, +46 deaths since 23 hours ago21:11
de-factoOmidelta21:22
darsiedeltoid21:37
darsieHow many covid viruses does a human produce during covid?21:37
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): On the harassment of scientists during the pandemicscience.org/doi/epdf/10.11… @ScienceMagazine @cathleenogrady @KelPFranklin pic.twitter.com/Mtbplij1G8 → https://twitter.com/EricTopol/status/150709366201393152721:38
LjLde-facto, i ask because21:45
LjL%print https://twitter.com/EnemyInAState/status/150676815498229350721:45
BrainstormLjL, It says: Chris Turnbull (@EnemyInAState): "1/ CDC China Stark Warning On Deltacron: 'The “Wolf” Is Indeed Coming' Recombination variant is a 'Grey Rhino' event (highly predictable, slowly emerging, obvious threat that is ignored or minimized by decision-makers) Past variants may not have been 'worst-case until now..." | 42l - nitter21:45
LjL%ocr https://twitter.com/EnemyInAState/status/150676815498229350721:45
BrainstormLjL, It says: Chris Turnbull (@EnemyInAState): "1/ CDC China Stark Warning On Deltacron: 'The “Wolf” Is Indeed Coming' Recombination variant is a 'Grey Rhino' event (highly predictable, slowly emerging, obvious threat that is ignored or minimized by decision-makers) Past variants may not have been 'worst-case until now..." | Hungary-based nitter instance by Hackerspace Szeged21:45
LjLhmpf21:45
LjLi really really hate Wayland copypaste21:46
LjL%ocr https://pbs.twimg.com/media/FOkezvDXMAA-Rza?format=jpg&name=medium21:46
BrainstormLjL, It says: Per ana e ROeN Te nn aE aN e MR aa ANOLE ER NL eae ee Na A Ue TT eae A OnSite oN N eT eine of the pandemic. As announced, this novel strain has high genomic similarity to viruses belonging to lineage AY.4, except for the region encoding the spike (S) gene, which is more similar to those from lineage BA.1 (Figure 1A). Therefore, this novel strain uses Delta as its [... want %more?]21:46
LjLthis poster is prone to extreme views, like21:48
LjL%print https://twitter.com/EnemyInAState/status/150677880063749734621:48
BrainstormLjL, It says: Chris Turnbull (@EnemyInAState): "15/ Unfortunately, rather than listening to the early warning given about Deltacron in January by Prof Kostrikis and others—the establishment criminal lying psychopaths decided to deny what was happening." | Hungary-based nitter instance by Hackerspace Szeged21:48
LjLbut anyway here is the report https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2022.05421:48
BrainstormUpdates for France: +140141 cases, +114 deaths since 23 hours ago22:07
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The Omicron wave in South Korea compared with Japan. Despite a 2-fold higher booster vaccination %, a noteworthy difference in fatality rate and divergence of the curves@OurWorldinData pic.twitter.com/v1ESzDpRUm → https://twitter.com/EricTopol/status/150710107477516288822:08
LjLwhy indeed22:09
LjLoh come on. "PICU admission was higher for Omicron than other SARS-CoV-2 variants (OR=18.50, 95% CI 2.42-140.70, p=0.005)"22:18
LjLhttps://papers.ssrn.com/sol3/papers.cfm?abstract_id=406303622:18
LjLwhat sort of ridiculous confidence interval is that22:18
LjL%print https://twitter.com/EricTopol/status/150709688019009126522:21
BrainstormLjL, It says: Eric Topol (@EricTopol): "Your attempt to negate their findings is duly noted. Their report has far more concerning data beyond CFR and CHR than what you selectively responded to." | 42l - nitter22:21
LjLsigh, petty fighting among expert gives such a beautiful picture22:21
LjL(he's responding to Francois Balloux)22:21
BrainstormUpdates for Cyprus: +5186 cases since 23 hours ago — United Kingdom: +98422 cases since 20 hours ago23:04
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): No, we should not accept our health authorities doing a bait and switch so that companies can sell outdated vaccines.A major goal with vaccines has always been to reduce the amount of infections. When vax are actually well made, that's very [... want %more?] → https://twitter.com/michaelzlin/status/150711563088491724823:06
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): We would have had >6mo protection after a 3rd dose of pretty much any vaccine (other than no repeating J&J), if SARSCoV2 had not mutated. Now that it did, the right reaction isn't to give up on controlling the intensity and speed of new waves. It's [... want %more?] → https://twitter.com/michaelzlin/status/150711730205920870423:16
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): If we say vaccines are only to prevent hospitalizations, and people actually believe that, that *removes* motivation for annual boosters. Heck it removes motivation for vaccination to begin with, since the young and healthy know their chance of [... want %more?] → https://twitter.com/michaelzlin/status/150712123483168359423:35
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The vax were made to a strain that's now extinct and as distantly related to Omicron in the RBD as SARS1. VE = 65% for Omicron vs 95% for original strain is a big difference. 95% can suppress a virus with inherent R0 = 20. 65% can only suppress a [... want %more?] → https://twitter.com/michaelzlin/status/150712493930790502523:53

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