Brainstorm | New from The Lancet (Online): [Correspondence] Breakthrough SARS-CoV-2 infections during periods of delta and omicron predominance, South Africa: The omicron variant of SARS-CoV-2 (B.1.1.529) was first detected in South Africa in November, 2021.1–3 Declared a variant of concern on Nov 26, [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01190-4/fulltext | 00:36 |
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Brainstorm | Updates for Brazil: +76850 cases, +296 deaths since 23 hours ago — India: +22621 cases since 23 hours ago — Malaysia: +3561 cases, +5 deaths, +58399 tests since 22 hours ago — Mauritania: +196 cases since a day ago | 00:59 |
Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Some countries, like Singapore, have already hit 2nd highest case peak after Omicron BA.1 pic.twitter.com/JEUTK7Kp0Z → https://twitter.com/EricTopol/status/1544825058345988096 | 01:35 |
Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) InfectionIt takes some days, 9!, but is very person dependent. nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/1544830368993447936 | 01:54 |
Brainstorm | Updates for South Korea: +18503 cases, +10 deaths since 21 hours ago — Croatia: +1794 cases, +4 deaths, +4677 tests since a day ago — Trinidad and Tobago: +195 cases, +4 deaths since a day ago — Guyana: +144 cases, +2 deaths since a day ago | 02:08 |
Brainstorm | New from Ars Technica: Biz & IT: Why Lockdown mode from Apple is one of the coolest security ideas ever → https://arstechnica.com/?p=1864722 | 02:33 |
Brainstorm | Updates for Slovakia: +2996 cases since a day ago | 03:05 |
Brainstorm | New from r/Coronavirus: Coronavirus: New Covid Vaccine (SKYCovione) out of University of Washington outperforms AstraZeneca, South Korea orders 10 mil doses. Does not require cold storage like mRNA vaccines → https://old.reddit.com/r/Coronavirus/comments/vt55ng/new_covid_vaccine_skycovione_out_of_university_of/ | 03:59 |
Brainstorm | Updates for Australia: +41559 cases, +45 deaths since 23 hours ago | 04:07 |
Brainstorm | New from r/COVID19: COVID19: Clinical and Economic Impact of COVID-19 on Agricultural Workers, Guatemala → https://old.reddit.com/r/COVID19/comments/vt6z72/clinical_and_economic_impact_of_covid19_on/ | 04:28 |
Brainstorm | Updates for New Zealand: +11790 cases, +11 deaths since a day ago — Lebanon: +1921 cases since 6 hours ago — Haiti: +90 cases since 2 days ago — Rwanda: +73 cases, +4015 tests since a day ago | 05:04 |
Brainstorm | New from r/COVID19: COVID19: Reductions in stillbirths and preterm birth in COVID-19 vaccinated women: a multi-center cohort study of vaccination uptake and perinatal outcomes → https://old.reddit.com/r/COVID19/comments/vt7yme/reductions_in_stillbirths_and_preterm_birth_in/ | 05:25 |
Brainstorm | Updates for Germany: +135402 cases, +108 deaths since a day ago — Mexico: +31116 cases, +60 deaths, +48244 tests since a day ago — Peru: +6004 cases, +19 deaths, +50921 tests since a day ago — Thailand: +2366 cases, +20 deaths since a day ago | 06:00 |
Brainstorm | New from r/Science: science: Lack of SARS-CoV-2-specific cellular response in critically ill COVID-19 patients despite apparent effective vaccination | Critical Care → https://old.reddit.com/r/science/comments/vt9t5s/lack_of_sarscov2specific_cellular_response_in/ | 07:00 |
Brainstorm | Updates for Bolivia: +2467 cases, +4 deaths since 22 hours ago — Pakistan: +872 cases, +23125 tests since 22 hours ago | 07:03 |
Brainstorm | New from BBC Health: Long Covid: Midwife's anger over new no-pay rule in NHS: Sarah Sutton faces not getting any sick pay due to ongoing health issues keeping her off work. → https://www.bbc.co.uk/news/uk-wales-62064477 | 07:29 |
Brainstorm | Updates for England, United Kingdom: +120132 cases, +301 deaths since 4 days ago — Scotland, United Kingdom: +22798 cases since 6 days ago — Georgia, United States: +19989 cases, +106 deaths since 6 days ago — Baden-Wurttemberg, Germany: +17725 cases, +7 deaths since 23 hours ago | 08:00 |
Brainstorm | New from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): I'm thrilled to share that I am the 2022 recipient of the Johanna Dürmüller-Bol #DBMR @DBMR_UniBe Research Award!My proposal focuses on investigating the impact of pandemic restrictions on #Enterovirus D68 #EVD68 - here's my 3 min finalist video!youtu.be/5UVe_wBjItM → https://twitter.com/firefoxx66/status/1544930045214752768 | 08:27 |
Brainstorm | New from r/Coronavirus: Daily Discussion Thread | July 07, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/vtcdc0/daily_discussion_thread_july_07_2022/ | 09:05 |
Brainstorm | Updates for Uzbekistan: +94 cases since a day ago | 09:09 |
Brainstorm | New from COVID on Twitter: Josiah Grindrod is usually self limiting (@JT_Grindrod): Some people seem to think I'm taking a swipe at the people being cautious but catching it anyway from people that they're forced to be around, so, to be clear, this is aimed at the people that have decided to pretend it's 2019 again [... want %more?] → https://twitter.com/JT_Grindrod/status/1544958534567215105 | 10:21 |
Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): CDC warns against travel to Norway for non-boosted or vulnerable people due to high risk of contracting COVID. IF YOU GO, WEAR A WELL-FITTING MASK. This is a dangerous, reckless country. wwwnc.cdc.gov/travel/notices… pic.twitter.com/F6frYssH4U → https://twitter.com/GANyborg/status/1544965420821741568 | 10:50 |
Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Why? The doctors who have been touted as our best specialists in the field - by themselves, the media, politicians, and all those insisting the pandemic be over no matter what - have over time followed these capitalists’ interests instead of [... want %more?] → https://twitter.com/GANyborg/status/1544968428422823937 | 11:00 |
Brainstorm | Updates for Kerala, India: +4113 cases, +19 deaths since 23 hours ago — Tamil Nadu, India: +2743 cases since 23 hours ago — West Bengal, India: +2352 cases, +3 deaths since 23 hours ago — Sindh, Pakistan: +1277 cases, +4 deaths since 2 days ago | 11:01 |
Brainstorm | New from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): This conclusion therefore does not hold, and is not justified: vaccination and infection build up immunity: it strengthens and improves and the effects of infection will decrease further. pic.twitter.com/8b9lp4Hsfz → https://twitter.com/Marc_Veld/status/1544970698380263424 | 11:10 |
Brainstorm | New from BMJ: Pulse oximetry and the pandemic: At the height of the covid-19 pandemic large numbers of patients with acute respiratory symptoms needed to be assessed, triaged, and monitored to identify those requiring admission to hospital and... → http://www.bmj.com/content/378/bmj-2022-071474.short | 11:57 |
Brainstorm | Updates for Slovenia: +1654 cases since 22 hours ago — Poland: +1068 cases, +9 deaths since a day ago | 12:04 |
Brainstorm | New from ScienceNews: College COVID-19 testing can reduce coronavirus deaths in local communities: Counties with colleges that did COVID-19 testing fared better against the coronavirus in fall 2020 than towns with colleges that did not test. → https://www.sciencenews.org/article/covid-testing-college-campus-coronavirus-deaths-communities | 12:07 |
Brainstorm | Updates for Russia: +3359 cases, +52 deaths since a day ago — Canada: +2242 cases since 17 hours ago | 13:07 |
Brainstorm | New from The Atlantic: How Are We Possibly Still Disinfecting Things?: Two weeks into the pandemic, a box of Cheerios sent me into an existential tailspin. I’d just returned from an unnerving trip to a New York City supermarket, where bandanna-masked customers [... want %more?] → https://www.theatlantic.com/health/archive/2022/07/covid-spread-air-disinfect-sanitize-hygiene-theater/661507/ | 13:15 |
Brainstorm | New from COVID on Twitter: Squawk Box (@SquawkCNBC): "There's probably more Monkeypox in communities that are presenting with STDs than what we're detecting. It's probably more broadly found in the community than what's currently being picked up," says @ScottGottliebMD. "It won't become widely epidemic like Covid." [... want %more?] → https://twitter.com/SquawkCNBC/status/1545005242156257280 | 13:34 |
Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 07JUL22 → https://old.reddit.com/r/nCoV/comments/vtgtij/global_covid_cases_for_07jul22/ | 13:54 |
Brainstorm | Updates for UAE: +1688 cases, +271133 tests since a day ago | 14:03 |
Brainstorm | New from BMJ: Tom Nolan’s research reviews—7 July 2022: Culture clubThis week’s Education pages in The BMJ include a guide to the uncertainties and complexities of a seemingly simple question: how long do you stay infectious for after covid-19... → http://www.bmj.com/content/378/bmj.o1644.short | 14:33 |
Brainstorm | New from Novavax: (news): European Medicines Agency Approves SK bioscience as a Supplier of Novavax Nuvaxovid COVID-19 Vaccine → https://ir.novavax.com/European-Medicines-Agency-Approves-SK-bioscience-as-a-Supplier-of-Novavax-Nuvaxovid-TM-COVID-19-Vaccine | 14:43 |
Brainstorm | New from Reddit (test): nCoV: It's too early to tell if Omicron sub-variant BA.2.75 is more severe says WHO chief scientist | 07JUL22 → https://old.reddit.com/r/nCoV/comments/vthwyj/its_too_early_to_tell_if_omicron_subvariant_ba275/ | 14:53 |
Brainstorm | Updates for Indonesia: +2881 cases, +6 deaths, +76507 tests since a day ago — Philippines: +1863 cases, +3 deaths, +22570 tests since a day ago — North Macedonia: +342 cases, +2 deaths, +1129 tests since 21 hours ago — Fiji: +237 cases, +4956 tests since 2 days ago | 14:59 |
Brainstorm | New from Science-Based Medicine: Melatonin poisonings in children are increasing: Melatonin use is increasing, and accelerated during the pandemic. Overdoses are also increasing in children, and in rare cases are linked to serious harms. The post first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/melatonin-poisonings-in-children-are-increasing/ | 15:02 |
Brainstorm | New from Reddit (test): nCoV: US FDA allows pharmacists to prescribe Pfizer's Covid-19 pill | 07JUL22 → https://old.reddit.com/r/nCoV/comments/vtis1u/us_fda_allows_pharmacists_to_prescribe_pfizers/ | 15:31 |
Brainstorm | New from Reddit (test): nCoV: Hong Kong lifts flight ban citing 'little effect' on COVID-19 | 07JUL22 → https://old.reddit.com/r/nCoV/comments/vtiyg7/hong_kong_lifts_flight_ban_citing_little_effect/ | 15:42 |
Brainstorm | New from Il Sole 24 Ore: (translated) Covid, about 10 thousand hospitalizations but half is for other pathologies: The fifth wave of infections threatens to send hospitals into a tailspin again this summer if we do not soon run for cover with directives or guidelines to manage numbers [... want %more?] → https://www.ilsole24ore.com/art/covid-10mila-ricoveri-ma-meta-e-altre-patologie-AEmAcekB | 15:52 |
Brainstorm | Updates for Hong Kong: +3028 cases, +1 deaths since a day ago — Iran: +1775 cases, +7 deaths, +392433 tests since a day ago — Malta: +624 cases, +1 deaths, +2279 tests since a day ago | 16:02 |
Brainstorm | New from r/COVID19: COVID19: Retinal microvascular impairment in COVID-19 patients: A meta-analysis → https://old.reddit.com/r/COVID19/comments/vtjjwl/retinal_microvascular_impairment_in_covid19/ | 16:21 |
Brainstorm | New from BMJ: Removing special covid leave will only undervalue staff and threaten patient safety: The Office for National Statistics (ONS) estimates that two million people (3% of the population) in the UK currently have long covid. Of those, 1.4 million say the symptoms are adversely affecting... → http://www.bmj.com/content/378/bmj.o1684.short | 16:32 |
Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The power of #SARSCoV2 wastewater sequencing to detect multiple important variants well before they are manifest clinicallynature.com/articles/s4158…Just published @Nature @KnightLabNews @K_G_Andersen @smruthi_karthik @UCSanDiego @UCSDHealth @SanDiegoCounty [... want %more?] → https://twitter.com/EricTopol/status/1545062032579256321 | 17:11 |
Brainstorm | Updates for Iraq: +4774 cases, +4 deaths since a day ago | 17:11 |
Timvde | I probably got infected last Friday night, I did a PCR test on Wednesday morning which got a result of 2.29 log copies/mL (which is quite low; probably not contagious). Should I still expect it to get worse? I'd expect the viral load on day 5 to be about at its peak. | 17:16 |
dTal | What made you get a test? | 17:28 |
Brainstorm | New from ClinicalTrials.gov: (news): Clinical Study to Evaluate the Effect of Food Supplement in People Infected With Coronavirus → https://clinicaltrials.gov/ct2/show/NCT05446961 | 17:41 |
Brainstorm | New from ClinicalTrials.gov: (translated) (news): 64 / 5.000 eviri sonuçları Effect of Vitamin D Intake on IgG of COVID-19 Vaccine Recipients → https://clinicaltrials.gov/ct2/show/NCT05447065 | 17:51 |
Brainstorm | New from ClinicalTrials.gov: (news): Value of Montelukast as a Potential Treatment of Post COVID-19 Persistent Cough → https://clinicaltrials.gov/ct2/show/NCT05447039 | 18:00 |
Brainstorm | Updates for Cuba: +43 cases since 22 hours ago — Marshall Is.: +12 cases since a day ago | 18:01 |
Timvde | dTal: a cough and mildly aching troat a couple of days after I visited a mass event | 18:06 |
Timvde | Hence the "I probably got infected last Friday" | 18:07 |
Timvde | First symptoms Tuesday, test Wednesday morning | 18:08 |
Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Estimated Number of COVID-19 Infections, Hospitalizations, and Deaths Prevented Among Vaccinated Persons in the US, December 2020 to September 2021COVID-19 vaccines have prevented 27 million infections, 1.6 million hospitalizations and 235,000 [... want %more?] → https://twitter.com/Marc_Veld/status/1545076210962731012 | 18:10 |
dTal | Timeline sounds about right. It sounds like a mild case. | 18:10 |
dTal | Touch wood, it's probably all uphill from here for you. | 18:10 |
Timvde | That'd be great :) | 18:11 |
Timvde | Still gonna skip the wedding next Saturday though, kinda sad about it :( | 18:11 |
Timvde | But thanks for confirming :) | 18:13 |
Timvde | Maybe I'll go on a walk in the forest or something | 18:13 |
dTal | well don't take my word for it | 18:18 |
dTal | just take it easy for a bit | 18:18 |
Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): A positive aspect of our case is when Antiretroviral therapy suppressed HIV and cleared SARS-CoV-2 within 6-9 weeks. Increased vigilance is warranted to benefit affected individuals and prevent the emergence of novel SARS-CoV-2 variants. → https://twitter.com/Tuliodna/status/1545078338208899074 | 18:20 |
Timvde | dTal: sure, not gonna do anything too exhaustive | 18:21 |
Timvde | But I'd be surprised if going on a 30 minute walk would be worse for my health than sitting in my room for a week | 18:22 |
Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): We have not used variant updated vaccines (this autumn?), and work on pan-coronavirus vaccines, mixed boosting, and nasal application is ongoing.So, even if another dose is better: we are getting through and out of this pandemic! → https://twitter.com/Marc_Veld/status/1545083138572951564 | 18:40 |
Brainstorm | New from Reddit (test): Covid2019: Ischemic stroke risk may be higher after COVID-19 compared to flu or bacterial pneumonia → https://old.reddit.com/r/Covid2019/comments/vtn1ni/ischemic_stroke_risk_may_be_higher_after_covid19/ | 18:49 |
Timvde | Follow-up question: they're probably starting a roll-out of extra boosters in September | 18:56 |
Timvde | Should I wait a couple more months before getting mine? | 18:56 |
de-facto | Timvde, a single swab test is not able to determine a metric about viral load | 19:00 |
de-facto | there is too much statistical noise about taking samples | 19:01 |
de-facto | CT values only possibly can give any clue about viral loads if a lot of samples taken (thousands) are averaged from the same pipeline | 19:01 |
Brainstorm | Updates for Italy: +108386 cases, +94 deaths, +378250 tests since a day ago — Serbia: +1469 cases, +3 deaths, +8594 tests since a day ago | 19:04 |
de-facto | Timvde, i guess you should isolate for 10 days, eat healthy (anti-inflammatory) foods, drink enough (including normal amounts of Green/Black tea), try to maintain a regular sleeping schedule (it got a big impact on immune system abilities), do some moderate mobilization (e.g. going for walks in the nature away from any people) while avoiding high pulse rates for the coming weeks (up to a month or such) | 19:05 |
Timvde | de-facto: hmm, it did say a specific number, weird | 19:05 |
Timvde | I'm obviously planning to isolate :) I didn't know about tea being helpful? | 19:07 |
de-facto | yes of course they can give you such a number, its correct for that sample they took, but the question would be: how much variation would emerge from the particular way they took that sample (e.g. if they would have swabbed a few seconds longer with it) or what history emerged directly before taking that sample (e.g. right after waking up in the morning not having heaten or drunk anything, or later in the day after multiple times having cleared the | 19:08 |
de-facto | mucus surfaces etc) | 19:08 |
ecks | our lab reports ct values on request but says something like "high viral load, likely highly contagious" when (i suppose) the ct value is below a certain threshold | 19:08 |
Timvde | I think I'm technically not allowed to go on a walk even... But that sounds a bit stupid | 19:08 |
Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmissionImportant for early detection, analysis and flagging for monitoring in the infected population.nature.com/articles/s4158… → https://twitter.com/Marc_Veld/status/1545091667325321216 | 19:08 |
de-facto | Timvde, you can also turn up the music and dance a bit or such things :) | 19:09 |
Timvde | Also true :D | 19:09 |
de-facto | it most likely will be Omicron BA.5 you catched, its highly contagious and immune evasive, possibly slightly more aggressive than BA.2 in terms of infecting lung cells, but since you are vaccinated a progression to severe disease is unlikely | 19:11 |
Timvde | We're at 70% BA.5 here, I believe | 19:12 |
de-facto | just make sure you really end this infection chain, it will save quite a lot of potential cases from being infected in the future as we are on exponential increase right now | 19:12 |
Timvde | The rest is divided between BA.2 and BA.4 | 19:12 |
de-facto | .be or .de? | 19:13 |
Timvde | be | 19:13 |
de-facto | yes pretty similar then i guess | 19:13 |
de-facto | it came form the west of Europe (e.g. Portugal/Spain) as a wave over all EU countries, ofc including France, Belgium, Germany, etc | 19:15 |
de-facto | its now taking over almost all countries worldwide | 19:16 |
de-facto | %title https://covariants.org/per-country | 19:16 |
Brainstorm | de-facto: From covariants.org: CoVariants: Per Country | 19:16 |
Timvde | Does it really still resembly BA.1 that much? Or why are we still calling it BA.n instead of giving it a new letter? | 19:16 |
de-facto | %title https://covariants.org/variants they call the BA.2 https://covariants.org/variants/22B.Omicron | 19:17 |
Brainstorm | de-facto: From covariants.org: CoVariants: Variants | 19:17 |
de-facto | %title https://covariants.org/shared-mutations they share mutations | 19:17 |
Brainstorm | de-facto: From covariants.org: CoVariants: Shared Mutations | 19:17 |
de-facto | Timvde, i am curious, do you know where you got infected? | 19:18 |
Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The immmunocompromised (IC) with Covid, 12% of US 10-state sample, with increased adverse outcomes of ICU admissions and deathNew @CDCgov @CDCMMWR cdc.gov/mmwr/volumes/7…This condition, w/ attendant risk, is common and not getting adequate respect among the [... want %more?] → https://twitter.com/EricTopol/status/1545093808806735872 | 19:18 |
Timvde | de-facto: I went to a large indoor event of about 15k people last Friday | 19:18 |
Timvde | So... probably there :P | 19:18 |
de-facto | oh yeah, that indeed sounds very much like a first suspect for that | 19:19 |
Timvde | I have only met people in private since then, and none of them have gotten sick | 19:19 |
de-facto | still tell them to get a test | 19:19 |
Timvde | I did inform all of them :) | 19:19 |
Timvde | But I mean: it's unlikely I got it from any of them | 19:20 |
de-facto | its everywhere right now, we have a "refuge" from a COVID household in our household right now, she wants to avoid getting infected (hence came here but tests everyday). I still stay at distance though (as i know from other people that tested negative but still infected others) | 19:21 |
de-facto | it may be that symptoms (and becoming infectious) start prior to tests coming back positive | 19:22 |
Timvde | Yes, I still tested negative on a self-test on Tuesday | 19:22 |
de-facto | or of course the famous asymptomatic spread, so completely unaware spreading | 19:22 |
de-facto | when did your self test became positive? | 19:23 |
Timvde | Wednesday, after I had the positive PCR test | 19:23 |
de-facto | interesting, so you probably started to become infectious before your rapid antigen test came back positive then | 19:24 |
de-facto | its a sharp exponential rise of viral load in the first days | 19:24 |
Timvde | When is "the first days"? | 19:24 |
de-facto | i think most common incubation period with current Omicron is ~3 days or such | 19:25 |
Timvde | I still tested negative at day 4, and positive at day 5 | 19:25 |
de-facto | maybe you got exposed to low contamination dose? | 19:26 |
de-facto | %title https://www.nature.com/articles/s41591-022-01780-9 | 19:26 |
Brainstorm | de-facto: From www.nature.com: Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults | Nature Medicine | 19:26 |
Timvde | But I'm glad that I tested positive on a self-test, now I can take testing negative on another one as a necessary but insufficient requirement of leaving quarantine :) | 19:26 |
de-facto | look at their figure 2 they plotted viral load (not for omicron though) | 19:27 |
Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Did COVID vaccine mandates work? What the data sayA measure of last resort got a major workout during the pandemic. Scientists are now trying to determine whether the benefits outweighed the potential damage to public trust.nature.com/articles/d4158… → https://twitter.com/Marc_Veld/status/1545095049079390209 | 19:28 |
Timvde | de-facto: wow, that's a lot longer than I thought | 19:28 |
de-facto | "36 volunteers aged 18–29 years without evidence of previous infection or vaccination were inoculated with 10 TCID50 of a wild-type virus (SARS-CoV-2/human/GBR/484861/2020) intranasally in an open-label, non-randomized study" | 19:28 |
de-facto | so your infectiousness is going to peak soon i guess | 19:30 |
Timvde | day 7-ish? | 19:30 |
de-facto | with their conditions there it looks like that yeah | 19:30 |
de-facto | but they did not use vaccinated individuals nor did they use Omicron BA.5 | 19:31 |
de-facto | so results may vary | 19:31 |
de-facto | but it gives a rough idea about viral load in both, aPCR tests as well as infecitous virions able to infect cell cultures | 19:31 |
de-facto | about roughly a week after exposure the immue system seems to be able to fight the viral load down | 19:32 |
de-facto | with your question about vaccination: your infection now gives your immune system an update on the latest VoC in circulation, BA.5 hence you most likely wont really need to update that in september if no new nasty variant occurs for which updated vaccines would be released | 19:34 |
Timvde | The new vaccines are BA.1 based anyway, right? | 19:35 |
de-facto | e.g. your immune system will be more up-to-date than vaccines based on BA.1/2 + Wuhan-Hu-1 | 19:35 |
de-facto | i think so yes Timvde | 19:35 |
Timvde | Yea, I thought so | 19:35 |
Timvde | But taking another booster later (like November or December) would probably still make sense, right? | 19:36 |
de-facto | do you have an officially certified PCR test result? | 19:36 |
Timvde | Yes | 19:36 |
de-facto | good | 19:36 |
Timvde | Why does that matter? :p | 19:36 |
de-facto | Timvde, its hard to say what will happen in Nov/Dec, lets wait and decide then | 19:36 |
de-facto | because it may document your updated immunity status | 19:37 |
Timvde | de-facto: sadly, the result didn't say whether I did catch BA.5 or another one | 19:43 |
de-facto | it would present with an S-gene target failure for some kinds of PCR tests | 19:46 |
de-facto | Timvde, as you see in https://covariants.org/shared-mutations BA4./5 got the de-69-70 just like Alpha, BA.1 but NOT BA.2 | 19:47 |
de-facto | *deletion of S:H69 and S:V70 | 19:47 |
de-facto | hence PCR tests targeting that part of the S-gene would fail that particular target while the other targets of the PCR test (i think all of them use multi-target nowadays) would still come back positive | 19:48 |
Timvde | de-facto: I got tested for N-gene and ORF1ab (whatever that is) | 19:48 |
de-facto | oh i see, N-gene is the nucleocapsid protein (where the viral RNA wraps around) and ORF1ab is the open reading frame 1 sections a and b | 19:49 |
de-facto | that codes for multiple viral proteins that later get sliced by the main protease | 19:49 |
de-facto | its quite unspecific as its a large section of the genome, therefore its not possible to determine the VoC from that PCR | 19:50 |
de-facto | they may have chosen any sub-sequence in that large area, not necessarily one specific to a VoC (most likely they would try to avoid that to cover all VoCs with their PCR sequences) | 19:51 |
de-facto | interesting that you get so many details about your PCR tests there | 19:52 |
de-facto | i think here they just would write "positive" | 19:52 |
de-facto | (though i dont know that for sure since i havent made a PCR in a year now) | 19:53 |
Timvde | It also notes that if only the N-gene test is positive but the ORF1ab test isn't, and the viral load is low, it's likely from an older infection and the result is considered negative. | 19:54 |
Timvde | (but both were positive for me) | 19:54 |
Brainstorm | Updates for Japan: +47943 cases, +15 deaths since 23 hours ago — Chile: +11082 cases, +68 deaths since 23 hours ago — Canada: +2367 cases since 23 hours ago | 20:00 |
Brainstorm | New from r/COVID19: COVID19: Multisystem Inflammatory Syndrome in Children and Long COVID: The SARS-CoV-2 Viral Superantigen Hypothesis → https://old.reddit.com/r/COVID19/comments/vton95/multisystem_inflammatory_syndrome_in_children_and/ | 20:25 |
de-facto | btw what are your symptoms now Timvde ? | 20:33 |
Timvde | de-facto: little cough (even less than yesterday) and a mildly aching troat | 20:37 |
de-facto | ok sounds good, maybe drinking some Green/Black tea could help with the sore throat, also by inactivating virions | 20:41 |
de-facto | no fatigue or such? | 20:41 |
Timvde | Not really, no | 20:49 |
Timvde | I'll go make some tea :) | 20:49 |
de-facto | good idea :) | 20:51 |
de-facto | %title https://www.mdpi.com/1420-3049/26/12/3572/htm | 20:53 |
Brainstorm | de-facto: From www.mdpi.com: Molecules | Free Full-Text | Significant Inactivation of SARS-CoV-2 In Vitro by a Green Tea Catechin, a Catechin-Derivative, and Black Tea Galloylated Theaflavins | HTML | 20:53 |
Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): @ScienceTM An experimental model of #LongCovid with lung scarring and immune cell dysfunction that recapitulates some features seen in people. Notably, an antiviral agent and an anti-scarring drug, when given early, helpedscience.org/doi/10.1126/sc… @Baric_Lab [... want %more?] → https://twitter.com/EricTopol/status/1545117363351142400 | 20:54 |
Timvde | Long COVID, that's what I'm mostly scared of :/ | 20:56 |
de-facto | yeah me too, not too much one can do about it yet, maybe some anti-inflammatory food or such (not sure if that helps at all though) | 20:57 |
de-facto | i think its auto-immune related so anything that helps against that may potentially also be of some help against long COVID, possibly (we really need trials on that) | 20:59 |
Timvde | Let's hope the tea does something in that regard | 21:00 |
Timvde | At least it won't harm, it's just tea :P | 21:00 |
de-facto | as long as you drink normal amounts of it (too much may be poisonous to the liver) its considered to be healthy in general yeah | 21:00 |
Timvde | I'm tbh surprised that there is even an effect | 21:00 |
Timvde | I usually drink 1 to 2 cups per week | 21:01 |
de-facto | plus it may inactivate some virions floating on the surface of the mucus as well as reducing inflammation of those areas | 21:01 |
Timvde | If I knew this before, I would've drank more tea :P | 21:02 |
Timvde | I wonder if it could have prevented the infection | 21:02 |
Timvde | but that's probably asking for too much | 21:02 |
de-facto | its unclear what the real effect is (as there are no double blinded trials on humans) but i think it does not hurt (as long as the consumed amounts dont accumulate to be hepa-toxic) | 21:03 |
Brainstorm | Updates for Malaysia: +4020 cases, +3 deaths since 20 hours ago — Sri Lanka: +20 cases, +1 deaths since a day ago | 21:03 |
Brainstorm | New from Contagion Live: Here’s How Many Infections, Hospitalizations, and Deaths Were Prevented by COVID-19 Vaccines: From December 2020-September 2021, approximately 27 million COVID-19 infections, 1.6 million hospitalizations, and 235000 deaths [... want %more?] → https://www.contagionlive.com/view/here-s-how-many-infections-hospitalizations-and-deaths-were-prevented-by-covid-19-vaccines | 21:03 |
de-facto | that paper i linked above only studied the inpact of Green and Black tea molecules on the ability of virions to infect cell cultures | 21:04 |
de-facto | why would we assume such effects would not also happen to a certain degree to such virions that happen to be on the surface of mucus (of course it would not affect such virions that currently are in the process of replication inside cells or deep inside tissue) | 21:05 |
peetaur | if tea works so well, why did India have such rates? | 21:06 |
de-facto | but at least the surface of parts of the upper respiratory tract as well as some part of the gastro-intestinal tract would at least potentially be affected by constantly drinking small amounts of tea | 21:06 |
de-facto | thats a good question peetaur, i assume they dont all constantly have tea on their mucus there? | 21:07 |
peetaur | but a counter example too... if I ever have any itchy dry throat, I drink tea, and I never seem to have had covid ;) | 21:08 |
de-facto | peetaur, note that i did not say it would work well, i just said it most likely would not mean any harm | 21:08 |
de-facto | it surely can not replace other measures to prevent infection | 21:09 |
Brainstorm | Updates for France: +161265 cases since 22 hours ago | 21:59 |
Brainstorm | New from WebMD: Each COVID-19 Reinfection Increases Health Risks: Researchers report a cumulative effect in a pre-print study looking at health effects of coronavirus reinfections. → https://www.webmd.com/lung/news/20220707/each-covid-19-reinfection-increases-health-risks | 22:02 |
Brainstorm | New from CIDRAP: COVID-19 vaccines may have saved 235,000 lives: Mary Van Beusekom | News Writer | CIDRAP News Jul 07, 2022 Researchers also estimate that vaccines averted 27 million infections and 1.6 million hospitalizations. → https://www.cidrap.umn.edu/news-perspective/2022/07/covid-19-vaccines-may-have-saved-235000-lives | 22:41 |
LjL | "... in the US" | 22:50 |
Brainstorm | New from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): What an honor to be featured in the latest BBC Science in Action with @Michelle_monje! We discuss our latest research on how mild respiratory COVID can cause multi-lineage neural dysregulation with @PeaseRoland. Many thanks to @AndrewLuckBaker [... want %more?] → https://twitter.com/VirusesImmunity/status/1545146669095944192 | 22:50 |
LjL | how i hate this deep-ingrained "US-only" perspective. okay you are a US thing, US media, whatever, but you can't say about a global pandemic that N people died or N people were saved without clearly adding *in your country* | 22:50 |
dTal | well don't worry the US will soon disintegrate and you won't have to worry anymore | 22:53 |
Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Duration of immune protection of SARS-CoV-2 natural infection against reinfection in QatarPre-print: Protection against severe reinfection remains very strong, with no evidence for waning, irrespective of variant, for >14 months after primary [... want %more?] → https://twitter.com/Marc_Veld/status/1545148067959242752 | 23:00 |
Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): BA.5 Covid in CaliforniaCases and hospitalizations both up 26% in past 2 weeksnytimes.com/live/2022/07/0… by @skarlamangla pic.twitter.com/3j9aNfsY7B → https://twitter.com/EricTopol/status/1545155002477395968 | 23:19 |
Timvde | dTal: I wish I could tell for sure that you were joking | 23:58 |
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