| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): What it was like doing randomized, placebo-controlled, double-blind trials in the early days of the pandemic, no less how important these were to make progress that we've seenacpjournals.org/doi/10.7326/M2…@AnnalsofIM by Kathleen Julian @PennStateID pic.twitter.com/SoEU44lvPE → https://twitter.com/EricTopol/status/1574526391982256128 | 00:34 |
|---|---|---|
| Brainstorm | New from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): This means that the data is twisted, somehow, with the wrong methods, to keep up the appearance that vaccines do not work/are safe. This is unscientific and very dangerous deception that some lend themselves to. Very sad and very disturbing! → https://twitter.com/Marc_Veld/status/1574529513484165120 | 00:43 |
| Brainstorm | Updates for Bahrain: +448 cases, +4841 tests since 23 hours ago — Monaco: +18 cases since 2 days ago | 01:01 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Some new immune response insights for #LongCovid (PASC)medrxiv.org/content/10.110… in people with rheumatic conditions1. Less anti-spike antibodies2. More non-#SARSCoV2 antibodies, particularly vs a common cold coronavirus (OC43)3. Evidence of imprinting from [... want %more?] → https://twitter.com/EricTopol/status/1574547078285361154 | 02:00 |
| Brainstorm | New from r/COVID19: COVID19: Detection of Messenger RNA COVID-19 Vaccines in Human Breast Milk → https://old.reddit.com/r/COVID19/comments/xp0fuz/detection_of_messenger_rna_covid19_vaccines_in/ | 02:35 |
| Brainstorm | Updates for Bulgaria: +1127 cases, +6 deaths, +7557 tests since a day ago — Norway: +105 cases since a day ago — Canada: +8 cases since 3 hours ago | 03:06 |
| Brainstorm | New from r/Science: science: Curing the pandemic of misinformation on COVID-19 mRNA vaccines through real evidence-based medicine - Part 2 | Malhotra → https://old.reddit.com/r/science/comments/xp0xq3/curing_the_pandemic_of_misinformation_on_covid19/ | 03:50 |
| Brainstorm | Updates for Portugal: +4805 cases, +17 deaths since 3 days ago | 04:08 |
| Brainstorm | Updates for Germany: +89282 cases, +118 deaths since 2 days ago — New Zealand: +9782 cases since 6 days ago | 05:10 |
| Brainstorm | New from BMJ Open: Partnerships in the introduction of new routine vaccines in Bangladesh: evidence from a prospective process evaluation: Objective To assess the contribution of partners in the introduction of two new vaccines concurrently: pneumococcal 10-valent conjugate vaccine (PCV-10) and inactivated polio vaccine [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/9/e061742 | 05:44 |
| Brainstorm | Updates for Antigua and Barb.: +81 cases, +1 deaths since 11 days ago | 06:00 |
| Brainstorm | New from r/Science: science: National CDC-funded study confirms that mRNA vaccines protect against serious COVID-19 during pregnancy → https://old.reddit.com/r/science/comments/xp60rb/national_cdcfunded_study_confirms_that_mrna/ | 07:18 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The ad does't say Pax, but the website does. Neither mentions drug-drug interactions, or that Pax was only proven to prevent hospitalization in the unvaccinated with risk factors, or people over 65yo, etc. → https://twitter.com/michaelzlin/status/1574632561648619520 | 07:36 |
| Brainstorm | Updates for Bavaria, Germany: +20804 cases, +8 deaths since 2 days ago — North Rhine-Westphalia, Germany: +16347 cases, +25 deaths since 2 days ago — Baden-Wurttemberg, Germany: +10232 cases, +16 deaths since 2 days ago — Hesse, Germany: +9203 cases, +4 deaths since 2 days ago | 08:04 |
| Brainstorm | New from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Vaccination helps. But you have to understand against what, and against what not.What soulless sad horn still calls it group goes straight to block. twitter.com/EdS196811/stat… pic.twitter.com/Xdhx3N4pwn → https://twitter.com/Marc_Veld/status/1574644206257451009 | 08:24 |
| Brainstorm | New from r/COVID19: COVID19: Lingering cardiac involvement in previously well people after mild COVID-19 → https://old.reddit.com/r/COVID19/comments/xp8nrf/lingering_cardiac_involvement_in_previously_well/ | 08:33 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | September 27, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/xp9axt/daily_discussion_thread_september_27_2022/ | 09:02 |
| Brainstorm | New from COVID on Twitter: Viki Male (@VikiLovesFACS): This study looked at #breastmilk after #CovidVaccination in 11 people. mRNA detectable in whole milk of 3 of them Maximum concentration 0.1 parts per billion This is roughly equivalent to a single tear in an Olympic pool1/jamanetwork.com/journals/jamap… → https://twitter.com/VikiLovesFACS/status/1574663804801388547 | 10:08 |
| Brainstorm | Updates for Taiwan: +45784 cases, +28 deaths, +79981 tests since a day ago | 10:08 |
| Brainstorm | New from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): This heap of sadness is now going to explain to us the difference between C19 vaccines and those against yellow fever (1938) and the Mumps Measles Rubella (MMR) vaccine (1980s). Then it will be explained why that difference makes the C19 vaccine [... want %more?] → https://twitter.com/Marc_Veld/status/1574673095985860608 | 10:18 |
| Brainstorm | New from r/COVID19: COVID19: Post COVID-19 condition after Wildtype, Delta, and Omicron variant SARS-CoV-2 infection and vaccination: pooled analysis of two population-based cohorts → https://old.reddit.com/r/COVID19/comments/xpappx/post_covid19_condition_after_wildtype_delta_and/ | 10:27 |
| Brainstorm | New from StatNews: Opinion: The Inflation Reduction Act will help the U.S. achieve maximum vaccine access and uptake, but access gaps remain: Vaccine coverage is a microcosm of the U.S. health care system's complexities. Achieving universal vaccine access requires an [... want %more?] → https://www.statnews.com/2022/09/27/inflation-reduction-act-improves-vaccine-access-but-gaps-remain/ | 10:46 |
| Brainstorm | Updates for Lithuania: +2224 cases, +2 deaths since a day ago | 11:11 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Vaxchora, cholera vaccine, oral, live, Cholera, Date of authorisation: 01/04/2020, Revision: 6, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/vaxchora | 11:23 |
| Brainstorm | Updates for Poland: +6482 cases, +25 deaths, +20991 tests since 23 hours ago | 12:00 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Good on state of the Ebola outbreak in #Uganda and potentially neighboring regions. It’s expanding quickly and the available vaccines were developed and tested against Ebola Zaire, not this Sudan strain twitter.com/kindrachukjaso… → https://twitter.com/ScottGottliebMD/status/1574702800591720448 | 12:20 |
| Brainstorm | New from r/COVID19: COVID19: Singularity and Commonality in Response to SARS-CoV-2 in Lung and Colon Cell Models → https://old.reddit.com/r/COVID19/comments/xpd8nm/singularity_and_commonality_in_response_to/ | 12:48 |
| Brainstorm | Updates for Slovenia: +3948 cases since 18 hours ago — Indonesia: +1976 cases, +21 deaths since 21 hours ago — Afghanistan: +207 cases, +2213 tests since a day ago — Liechtenstein: +69 cases since 23 hours ago | 13:03 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): "These findings suggest that inflammatory cardiac involvement after COVID-19 may be a pathophysiological commonality shared by all patients that is more pronounced in those with persistent cardiac symptoms." → https://twitter.com/GANyborg/status/1574716200197754881 | 13:07 |
| Brainstorm | New from r/COVID19: COVID19: Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis → https://old.reddit.com/r/COVID19/comments/xpe5cs/spatial_transcriptomic_profiling_of_coronary/ | 13:35 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 27SEP22 → https://old.reddit.com/r/nCoV/comments/xpemva/global_covid_cases_for_27sep22/ | 13:54 |
| Brainstorm | Updates for China: +3868 cases, +6 deaths since 18 hours ago — UAE: +334 cases, +1 deaths, +200273 tests since a day ago | 14:05 |
| Brainstorm | New from Reddit (test): nCoV: Science-based support for people suffering from long-term COVID-19 vaccine effects | For Patients | For Providers | Science & Research → https://old.reddit.com/r/nCoV/comments/xpf80x/sciencebased_support_for_people_suffering_from/ | 14:22 |
| Brainstorm | New from Novavax: (news): Novavax Makes One Million Doses of Nuvaxovid Available for Use in the United Kingdom → https://ir.novavax.com/2022-09-27-Novavax-Makes-One-Million-Doses-of-Nuvaxovid-TM-Available-for-Use-in-the-United-Kingdom | 14:31 |
| Brainstorm | Updates for Bangladesh: +737 cases, +1 deaths, +4781 tests since 23 hours ago — Spain: +8316 cases, +81 deaths since 3 days ago | 15:07 |
| Brainstorm | New from NIH Director's blog: Wearable Sensor Promises More Efficient Early Cancer Drug Development: Wearable electronic sensors hold tremendous promise for improving human health and wellness. That promise already runs the gamut from real-time monitoring of [... want %more?] → https://directorsblog.nih.gov/2022/09/27/wearable-sensor-promises-more-efficient-early-cancer-drug-development/ | 15:10 |
| Brainstorm | New from Contagion Live: us: Pfizer-BioNTech, Moderna Seek FDA EUA for Bivalent Vaccine Boosters in Pediatric Population → https://www.contagionlive.com/view/pfizer-biontech-moderna-seek-fda-eua-for-bivalent-vaccine-boosters-in-pediatric-population | 15:19 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): New @CellCellPress Why getting a booster too soon after Covid is not a good idea: suboptimal B-cell responsecell.com/cell/fulltext/…@NIAIDNews pic.twitter.com/GGMfM2OATG → https://twitter.com/EricTopol/status/1574754180673470464 | 15:38 |
| Brainstorm | New from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: FDA Updates COVID-19 Test Policy, Encourages Developers to Seek Traditional Premarket Review for Most Test Types → http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-updates-covid-19-test-policy-encourages-developers-seek-traditional | 15:57 |
| Brainstorm | New from COVID on Twitter: Florian Krammer (@florian_krammer): Waleed Abdurhman AlJabr, who I just met at the Options conference, asked me to broadcast the announcement for this conference on severe coronavirus infections. Looks very interesting and timely! Consider joining if you are in the area. pic.twitter.com/9dKiupjfhL → https://twitter.com/florian_krammer/status/1574761698040373254 | 16:07 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The persistent excess of arterial and venous blood clots after Covid at 1 year compared with controlsahajournals.org/doi/10.1161/CI… @CircAHA by @jonathanasterne and colleagues pic.twitter.com/Q0ONqbnHr3 → https://twitter.com/EricTopol/status/1574771499357339648 | 16:46 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Good summary @PopSci integrates findings from a 3rd report popsci.com/health/covid-1… by @LPBaisas → https://twitter.com/EricTopol/status/1574774199759306753 | 16:56 |
| Brainstorm | Updates for Singapore: +4360 cases since 23 hours ago — Qatar: +1617 cases since a day ago | 16:59 |
| Brainstorm | New from StatNews: Health: New study sees possible link between aluminum in childhood vaccines and risk of asthma, but caveats abound → https://www.statnews.com/2022/09/27/possible-link-aluminum-childhood-vaccines-asthma-risk-caveats/ | 17:05 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Women said covid shots affect periods. A new study shows they’re right. → https://old.reddit.com/r/Coronavirus/comments/xpjaci/women_said_covid_shots_affect_periods_a_new_study/ | 17:25 |
| peetaur | what's with all this "a new study shows what "quacks" have been saying is actually right" suddenly? did the censors stop censoring? | 17:28 |
| peetaur | who gets 2 covid vaccinations in 1 cycle?? "people who received two vaccinations within one menstrual cycle experienced greater disruptions" | 17:30 |
| skep | de-facto: there? | 17:32 |
| de-facto | yep | 17:32 |
| skep | y0 | 17:32 |
| skep | so any new infrence for covid third wave in India? | 17:32 |
| de-facto | isnt it "Centaur" Omicron BA.2.75 ? | 17:33 |
| skep_ | idk | 17:36 |
| skep_ | de-facto: any chance for complete lockdown? | 17:36 |
| de-facto | i dont think so | 17:38 |
| skep_ | ;( | 17:39 |
| de-facto | https://covariants.org/per-country | 17:39 |
| de-facto | https://covariants.org/variants/22D.Omicron | 17:39 |
| de-facto | 22D (Omicron) also known as BA.2.75 | 17:40 |
| skep_ | de-facto: you have done a crash course in virology | 17:42 |
| de-facto | skep_, i watched some of Vincent Racaniello lectures in virology at https://www.youtube.com/c/VincentRacaniello/playlists | 17:48 |
| skep_ | yeah I know | 17:49 |
| skep_ | now covid is not more a problem | 17:50 |
| de-facto | depends on the variants that emerge i guess | 17:53 |
| de-facto | i right now have the honor with BA.5 i guess | 17:53 |
| skep_ | sad man I need more terror | 17:54 |
| skep_ | de-facto: any nanotechnological virus is coming? | 17:56 |
| skep_ | it works upon EMF | 17:56 |
| de-facto | nope | 17:56 |
| de-facto | more terror definitely is coming though, just look into the news | 17:57 |
| skep_ | unleashed ;) | 17:59 |
| Brainstorm | Updates for Italy: +44875 cases, +64 deaths, +243421 tests since 23 hours ago — Netherlands: +6877 cases, +6 deaths since 12 hours ago — Serbia: +2747 cases, +14 deaths, +15519 tests since 21 hours ago | 18:01 |
| LjL-Matrix | That makes me cry | 18:03 |
| LjL-Matrix | We obviously are having another spike | 18:03 |
| LjL-Matrix | Next question: I don't remember having such a blatant spike unless there was a new variant | 18:04 |
| LjL-Matrix | So, are we getting a new variant? | 18:04 |
| LjL-Matrix | No PCR anymore, virtually no sequencing, maybe we'll know when it's over again | 18:04 |
| LjL-Matrix | Or, if the death rate goes from 0.8% to 5% or something like that, then I guess we'll also know | 18:04 |
| LjL-Matrix | Excuse me but: FUCK | 18:05 |
| LjL-Matrix | I have some issues I need, or let's say I'd benefit from, seeing doctors for, but now, while we have such a case growth, we no longer have a mask mandate even in clinics and hospitals. I'm simply not going. | 18:06 |
| LjL-Matrix | Is there any newish know variant wreaking some havoc elsewhere ATM? I've somewhat lost touch | 18:07 |
| de-facto | In India/Asia its BA.2.75 and in EU/US its BA.4.6 iirc | 18:08 |
| Brainstorm | New from BMJ: The new government’s plans bring the sustainability of the NHS into doubt: Last week’s announcement of the government’s plan for the NHS followed by a mini-budget, which was seen by many commentators as the most radical for many years, have worrying implications for the future of the NHS. They suggest that [... want %more?] → http://www.bmj.com/content/378/bmj.o2339.short | 18:12 |
| skep | %india | 18:13 |
| skep | de-facto: what is the suffix of bot command | 18:13 |
| skep | okay topic ;) | 18:14 |
| skep | %cases india | 18:14 |
| Brainstorm | skep: India has had 44.6 million confirmed cases (3.3% of all people) and 528562 deaths (1.2% of cases; 1 in 2574 people) as of 11 hours ago. 893.8 million tests were done (0.7 per capita, 5.0% positive). 857.8 million were vaccinated (63.1%). +1684 cases, +32 deaths since 7 hours ago. See https://www.mygov.in/covid-19 or https://www.covid19india.org/ | 18:14 |
| LjL-Matrix | Severely undercounted | 18:15 |
| LjL-Matrix | de-facto: how's today? | 18:16 |
| de-facto | good | 18:16 |
| de-facto | sore throat got better, otherwise feeling normal | 18:17 |
| LjL-Matrix | Nice | 18:17 |
| LjL-Matrix | Maybe you'll have Short Covid :) | 18:17 |
| de-facto | yes now you leaked my secret plan :P | 18:18 |
| * LjL-Matrix steal all of de-facto's green tea | 18:20 | |
| de-facto | oooh nooooo | 18:20 |
| * de-facto notes to himself not to reveal means of implementing secret plans in advance for the future | 18:21 | |
| * de-facto smiles and sips on a nice hot BLACK tea | 18:21 | |
| Brainstorm | New from BMJ Open: Economic evaluation of endovascular treatment for acute ischaemic stroke in Thailand: Objectives Endovascular therapy (EVT) has proven to be clinically effective in treating large vessel occlusion acute ischaemic stroke (AIS), either alone or in combination with intravenous alteplase. Despite this, [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/9/e064403 | 18:21 |
| * LjL-Matrix challenges de-facto with | 18:24 | |
| LjL-Matrix | %print https://mobile.twitter.com/EricTopol/status/1574555388669661184 | 18:24 |
| Brainstorm | LjL-Matrix, It says: Eric Topol on Twitter: "Coffee lovers will love this new report ;-) https://t.co/KYNVF3jm5I @escardio @BakerResearchAu @uk_biobank ☕️☕️☕️ https://t.co/XEchS57Ywf" / Twitter | 18:24 |
| * de-facto reveals to LjL-Matrix that he used to drink both, (Ravenblack) Coffee and (Green/Black) Tea | 18:26 | |
| Brainstorm | Updates for Myanmar: +356 cases since a day ago | 19:03 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Government announces lifting of compulsory quarantine requirement on arrival at Hong Kong → https://old.reddit.com/r/Coronavirus/comments/xple7e/government_announces_lifting_of_compulsory/ | 19:09 |
| dallas_bruno[m] | Click and thank me later | 19:14 |
| dallas_bruno[m] | 👇👇👇👇👇👇 | 19:14 |
| dallas_bruno[m] | http://t.me/Stevecoldham001 | 19:14 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): A very interesting report that adds to the possible underpinnings of #LongCovid. Reactivation of viruses such as EBV has been raised, along w/ persistent remnants/reservoir of #SARSCoV2, and autoimmunity. But imprinting from a common cold coronavirus is unlike these mechanisms → https://twitter.com/EricTopol/status/1574809074754940931 | 19:19 |
| LjL | ublx, he said "click", not "kick", have you had your hearing tested recently? | 19:21 |
| ublx | oops | 19:22 |
| * ublx pushes glasses up nose | 19:22 | |
| * LjL went to load up Matrix but i see you did the full job | 19:22 | |
| ublx | the matrix side ban, without the /kick just feels so impersonal somehow | 19:24 |
| LjL | heh | 19:24 |
| LjL | meanwhile Element thanked me by crashing and then requiring me to re-login and re-acquire trusted status upon reload | 19:25 |
| ublx | how does that trusted thing even work? i just escape past that dialog on my rare trips into the matrix | 19:26 |
| LjL-Matrix | ublx: it's a semi-automated shared secret. Things like XMPP with OMEMO have it too, it's just more manual | 19:26 |
| LjL-Matrix | ublx: Matrix also has a thing where the *server* stores your encryption keys, but, encrypted in a way that they can't see them. I kiiiind of believe that. But that's a separate thing anyway | 19:27 |
| LjL-Matrix | Right now it just wanted me to use another of my devices to re-verify this one | 19:27 |
| ublx | sounds like n-factor authentication | 19:27 |
| LjL-Matrix | If you have no other devices, the server-side thing can supposedly help | 19:27 |
| LjL-Matrix | ublx: no, it's different. One device is enough, so no n-factors. But other people do want to know that it's always use even though you're coming with different encryption keys (one per device). So imagine we're talking on an encrypted platform for the first time, yes it's encrypted, but how do I know it's you? Well, we could say something that we're the only ones knowing, a shared secret. But who says it first? Maybe I'm bluffing, I don't | 19:30 |
| LjL-Matrix | know it, you say it, I say "right!" (blindly), and you trust me (wrongly). Well, there's fancy math to solve that: we can both input the same string, and while we don't actually *send* the string itself to each other, we can send numbers that somehow prove that we did, in fact, input the same string | 19:30 |
| LjL-Matrix | I believe this is similar, but to verify other devices of yours rather than the other person | 19:30 |
| LjL-Matrix | and it's simplified by having QR codes (if your other device is a phone with a camera) or silly emoji to compare (not sure I call that simplification) instead of some cryptic string, but that's just cosmetic | 19:31 |
| ublx | and this all uses less bandwidth than just signing everything you send with half of your gpg key? | 19:32 |
| LjL-Matrix | s/use/you/, s/*send*/_send_/ | 19:33 |
| LjL-Matrix | Oh don't be ridiculous. GPG is completely different infrastructure and it PGP failed badly at adoption, and you have to basically trust the keyservers | 19:33 |
| LjL-Matrix | Here you don't trust any server | 19:33 |
| LjL-Matrix | Also I can't count how many email addresses I've got uploaded to keyservers that aren't valid anymore, yet I've lost the revocation certificates to | 19:34 |
| ublx | ;p | 19:36 |
| Klinda | did the queen died because of covid | 19:37 |
| LjL | it may have contributed, when you're 94 and get a disease... | 19:38 |
| LjL | it certainly wouldn't be counted as a "COVID death" though | 19:38 |
| LjL | her husband dying may also have contributed if you ask me | 19:38 |
| LjL | but chiefly, being 96 | 19:38 |
| Klinda | I heard she felt off | 19:38 |
| Klinda | and these caused compliactions and die | 19:39 |
| LjL | that's pure speculation. all she said was something like "this horrible disease does live you exhausted, doesn't it" | 19:39 |
| LjL | leave* | 19:39 |
| Klinda | well it's exhausted because of her age too | 19:39 |
| Klinda | lol | 19:40 |
| LjL | evidently she was feeling less exhausted before | 19:40 |
| Klinda | seems you are ruined for life if you get it | 19:40 |
| LjL | some people are | 19:41 |
| LjL | "you" as in everyone, no | 19:41 |
| Klinda | now they litteraly don't care if you get it or no | 19:41 |
| Klinda | I heard also that the last omicros are more deadly | 19:43 |
| LjL | unclear imo | 19:44 |
| Brainstorm | New from CIDRAP: News Scan for Sep 27, 2022: COVID antiviral resistance mutation Fecal transplant for C difficile DR Congo Ebola outbreak over → https://www.cidrap.umn.edu/news-perspective/2022/09/news-scan-sep-27-2022 | 19:47 |
| Brainstorm | Updates for Canada: +247 cases, +3 deaths since 20 hours ago | 20:05 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Current CDC recommendations> 2 months or > 3 months if recent infectioncdc.gov/vaccines/acip/…Comments—Unclear if there is any benefit of BA.5 bivalent booster w/ a prior BA.5 infection—"> 2 months" is vague, with little data to know if 3 or 4 months [... want %more?] → https://twitter.com/EricTopol/status/1574822136585166848 | 20:06 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): I think I've figured out why there is more #Paxlovid rebound and immunity suppression now than in the clinical trials. In short, vaccines, Omicron, and RATs have changed the temporal relationship between symptom onset and time of viral peak = time [... want %more?] → https://twitter.com/michaelzlin/status/1574823881528864768 | 20:15 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): In unvaxxed pre-Omicron viral loads are highest on the day of symptom onset. (You may recall the shock when first described, as it meant people you infect others before knowing you were sick, implying trouble for contact tracing.)Here's one article [... want %more?] → https://twitter.com/michaelzlin/status/1574828513231704064 | 20:34 |
| de-facto | %cases UA | 20:38 |
| Brainstorm | de-facto: Guatemala has had 1.1 million confirmed cases (6.7% of all people) and 19772 deaths (1.8% of cases; 1 in 840 people) as of 19 hours ago. 5.8 million tests were done (0.4 per capita, 19.2% positive). 6.5 million were vaccinated (39.4%). +58 cases, +7 deaths since a day ago. See https://offloop.net/covid19/?default=Guatemala&legacy=no | 20:38 |
| de-facto | %cases Ukraine | 20:38 |
| Brainstorm | de-facto: Ukraine has had 5.4 million confirmed cases (13.0% of all people) and 116868 deaths (2.2% of cases; 1 in 358 people) as of 7 hours ago. 19.5 million tests were done (0.5 per capita, 27.8% positive). 14.7 million were vaccinated (35.2%). +249 cases since a day ago. See https://covid19.rnbo.gov.ua/ | 20:38 |
| Brainstorm | New from Reddit (test): CoronavirusUK: UK’s autumn Covid wave could be worse than the last as cases rise → https://old.reddit.com/r/CoronavirusUK/comments/xpovmg/uks_autumn_covid_wave_could_be_worse_than_the/ | 20:44 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Now with Omicron and vax the incubation period (infection to symptoms) has decreased by two days. @michaelmina believes this is because even the low level of anti-Omicron responses after Wuhan vax are enough to induce symptoms. twitter.com/michaelmina_la… → https://twitter.com/michaelzlin/status/1574832508155281408 | 20:53 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The faster replication of Omicron on mucous membranes may contribute as well...this can lead to a bigger initial burst of virus that then leads to symptoms via adaptive and/or innate immunity.thelancet.com/journals/ebiom… → https://twitter.com/michaelzlin/status/1574832509736493056 | 21:03 |
| Brainstorm | Updates for Spain: +445 cases since 6 hours ago | 21:08 |
| Brainstorm | New from r/COVID19: COVID19: Hypertension is associated with antibody response and breakthrough infection in health care workers following vaccination with inactivated SARS-CoV-2 → https://old.reddit.com/r/COVID19/comments/xpp1xn/hypertension_is_associated_with_antibody_response/ | 21:12 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Association between menstrual cycle length and covid-19 vaccination: retrospective cohort study Covid-19 vaccination is associated with a small and likely to be temporary change in menstrual cycle length but no change in menses lengthbmjmedicine.bmj.com/content/1/1/e0… → https://twitter.com/Marc_Veld/status/1574842975829561364 | 21:31 |
| Brainstorm | Updates for France: +73639 cases, +40 deaths since a day ago | 22:10 |
| Brainstorm | New from CIDRAP: Report: COVID-19 has lowered lifespan across the Americas: Stephanie Soucheray | News Reporter | CIDRAP News Sep 27, 2022 The Americas house 13% of the world's people, but the region has seen 37% of global cases and 45% of deaths. → https://www.cidrap.umn.edu/news-perspective/2022/09/report-covid-19-has-lowered-lifespan-across-americas | 22:29 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Meanwhile there is reason to believe that starting Pax within 5d of infection may prevent development of immunity to the infecting strain. The evidence? The ~50% rebound rates in 2022, among vaxxed people who got Omicron and took Pax within 1d of [... want %more?] → https://twitter.com/michaelzlin/status/1574858507433541632 | 22:38 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The situation may be quite different once we have good immunity that target the circulating strains well. In that case, when a breakthrough case happens, someone could take Paxlovid early and have enough antibodies recognizing that strain to prevent rebound. → https://twitter.com/michaelzlin/status/1574862812295229440 | 22:48 |
| Brainstorm | New from CIDRAP: COVID-19 vaccines protect against severe outcomes but less so over time: Mary Van Beusekom | News Writer | CIDRAP News Sep 27, 2022 Efficacy held up during the Delta period and while several Omicron subvariants were circulating, [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/09/covid-19-vaccines-protect-against-severe-outcomes-less-so-over-time | 23:07 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Other lesson: details in experimental conditions matter (familiar to any experimental biologist). Yet we still see Pfizer, the CDC, the FDA citing Pfizer's increasingly irrelevant clinical trial to convince us Paxlovid rebounds are in our imagination. → https://twitter.com/michaelzlin/status/1574869124441722880 | 23:17 |
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