| Brainstorm | New from Virological.org: Latest topics: Rapid molecular sequence characterization of the SARS-CoV-2 variant of interest Lambda (C.37): Alexander G Lucaci 1 , Jordan D Zehr 1 , Stephen D Shank 1 , Steven Weaver 1 , Dave Bouvier 2 , Han Mei 2 , Anton Nekrutenko 2 , Sergei L Kosakovsky Pond 1 Institute for Genomics and Evolutionary Medicine, Temple [... want %more?] → https://is.gd/TinqL0 | 00:02 |
|---|---|---|
| pwr22 | Australia seems to have a super conservative news setup | 00:06 |
| pwr22 | It's all been anti covid measures | 00:06 |
| pwr22 | Calling the uk lockdowns fascist police state stuff all along | 00:06 |
| LjL | The Atlantic is an American paper | 00:07 |
| LjL | also aside from COVID, Australia's government is super conservative | 00:07 |
| pwr22 | Sure | 00:10 |
| LjL | i don't find it particularly impressive that they let Australians residing abroad enter Australian, and then trapped them in | 00:12 |
| nixonix | i think its not allowed to visit private homes if your buddies in sydney. maybe just some areas of it, not sure | 00:40 |
| nixonix | gladys, premier of nsw i think, had some strange speeches lately, where she painted rosy future when 70% have been fully vaccinated. they even made a mocking version of some of her speeches | 00:42 |
| nixonix | https://www.dailymail.co.uk/news/article-9945639/Coronavirus-Australia-Gladys-Berejiklian-reveals-one-restrictions-lifted-NSW.html | 00:43 |
| nixonix | it seems their states have a lot of power of their own | 00:44 |
| Brainstorm | New from Eric Topol: @EricTopol: The Delta wave impact in 14 countries by % vaccination and case spread—Israel, no longer in the top 10 for vaccination, is an outlier, > 100/100,000—the US and UK ~50/100,000—the rest are in descent or below 20/100,000Delta can be beat. 11 of 14 countries are doing it. → https://is.gd/FOO3IZ | 00:45 |
| nixonix | lambda is a variant of not much interest. ivermectin is a CoC, cure of concern | 00:46 |
| nixonix | oh, 70% of eligible. over 16 yo. 56% of all or something, they said in twitter. then everything will change *celebrates like randy marsh | 00:51 |
| * nixonix opens up the gate in shark pool | 00:51 | |
| Brainstorm | New from r/WorldNews: worldnews: Australia’s Home Quarantine App Uses Facial Recognition Technology To Make Sure You Haven’t Left Your House → https://is.gd/pq4nYK | 01:06 |
| Brainstorm | New from Eric Topol: @EricTopol: Hawaii had managed the pandemic well until Delta hit; the highest 1st dose vaccination rate for the US, 2nd dose above average. Hospitals are filled, 95% w/ unvaccinated residents. Oxygen is in shortage.A pattern seen in many island nations + [... want %more?] → https://is.gd/9t2mUQ | 01:17 |
| nixonix | yeah, we dont have much immunity from previous infections | 01:20 |
| nixonix | almost in island. so we are in the same ship. lets not call it Titanic | 01:23 |
| nixonix | in=an | 01:23 |
| nixonix | .title https://twitter.com/RogerSeheult/status/1433571394474811396 | 01:29 |
| Brainstorm | nixonix: From twitter.com: Roger Seheult, MD (@RogerSeheult): "Better to keep patients on high flow oxygen but high flow oxygen uses a lot more oxygen then ventilators. Hawaii is in a jam: [...] | 01:29 |
| nixonix | damn. another reason to keep the cases low | 01:29 |
| LjL | lol <Brainstorm> New from r/Coronavirus: Coronavirus: Florida school district no longer accepts mask opt-out forms from chiropractors → https://is.gd/xcwt6T | 01:42 |
| LjL | chiropractors, totally entitled to determine that you must not wear a mask | 01:42 |
| LjL | how even | 01:42 |
| nixonix | whats gene stacking, that leonardi keeps mentioning? does it mean that genes that differ with variants are both present, unlike in recombination? | 01:44 |
| specing | mask opt-outs, keeeek | 01:45 |
| LjL | i don't know | 01:45 |
| LjL | https://en.wikipedia.org/wiki/Gene_stacking seems to refer to something different, or if it's similar, then i don't know how | 01:45 |
| nixonix | do we have reliable results, that reinfections are less severe? | 01:52 |
| nixonix | in that danish study i think it wasnt apparent | 01:52 |
| nixonix | have to check tomorrow | 01:52 |
| nixonix | .title https://twitter.com/DrEricDing/status/1433352755696050177 | 01:57 |
| Brainstorm | nixonix: From twitter.com: Eric Feigl-Ding (@DrEricDing): "⚠️GOOD & BAD news on #DeltaVariant & vaccine effects on viral loads—Israel data now clearly shows waning of Pfizer jabs against Delta #COVID19 after 2 months—& then [...] | 01:57 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1433221043884281858 check the tweets above too. i was wondering what he meant before the answer | 01:59 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "reinfections are not assured to be less severe" | El Pajarito de NoGAFAM | 01:59 |
| Brainstorm | Updates for Dominica: +194 cases (now 1832) since 4 days ago — South Africa: +9202 cases (now 2.8 million), +418 deaths (now 82914), +57261 tests (now 16.6 million) since a day ago — Turkey: +5841 cases (now 6.4 million), +305047 tests (now 77.0 million) since 17 hours ago — Bulgaria: +1564 cases (now 459051), +51 deaths (now 19001), +25793 tests (now 4.3 million) since a day ago | 02:01 |
| Brainstorm | New from r/WorldNews: worldnews: Vaccine appointments more than doubled after Ontario Covid passport announcement. → https://is.gd/vx0o2C | 02:11 |
| Brainstorm | New from Virological.org: Latest posts: Genomic Surveillance of SARS-CoV-2 in the State of Rio de Janeiro, Brazil: technical briefing: [Update information - Genomic surveillance of the state of Rio de Janeiro, Brazil, in the period between August, 04th, 2021 and August, 16th, 2021] Since last update, we have sequenced new 377 SARS-CoV-2 genomes from [... want %more?] → https://is.gd/sFPG2a | 02:32 |
| Brainstorm | Updates for Palestine: +2773 cases (now 347730), +11 deaths (now 3699) since a day ago — Ukraine: +1959 cases (now 2.3 million), +42 deaths (now 55476) since 22 hours ago — France: +23988 cases (now 6.8 million), +2961 deaths (now 120469) since 22 hours ago — Tajikistan: +184 cases (now 17068), +1 deaths (now 125) since 12 hours ago | 02:38 |
| nixonix | As expected, the Delta variant (lineages B.1.617.2, AY.4, AY.5, AY.6, AY.7.1, AY.7.2, AY.12, AY.20 and AY.25) has become dominant in Rio de Janeiro and now corresponds to ~89.2% of the samples collected in August | 02:50 |
| Brainstorm | New from r/WorldNews: worldnews: Being fully vaccinated reduces odds of long Covid-19 by half, UK study suggests → https://is.gd/4j5zs2 | 02:53 |
| Brainstorm | New from r/WorldNews: worldnews: North Korea rejects offer of nearly 3 million Sinovac COVID-19 shots → https://is.gd/TB2oeR | 03:14 |
| Raf[m] | any talks of the mu variant in here yet? | 03:20 |
| Brainstorm | New from Virological.org: Latest topics: Evidence Against the Veracity of SARS-CoV-2 Genomes Intermediate between Lineages A and B: Jonathan Pekar, Edyth Parker, Jennifer L. Havens, Marc A. Suchard, Kristian G. Andersen, Niema Moshiri, Michael Worobey, Andrew Rambaut, Joel O. Wertheim Early SARS-CoV-2 genomic diversity can be separated into two [... want %more?] → https://is.gd/Cf4KtT | 03:25 |
| Brainstorm | New from r/WorldNews: worldnews: Australia’s Home Quarantine App Uses Facial Recognition Technology To Make Sure You Haven’t Left Your House → https://is.gd/6LX89F | 03:57 |
| Raf[m] | New coronavirus mutant called mu variant being monitored by World Health Organization https://www.bostonherald.com/2021/09/02/new-coronavirus-mutant-called-mu-variant-being-monitored-by-world-health-organization/ | 04:17 |
| LjL | i know it's being monitored, but that's all i know | 04:27 |
| Brainstorm | Updates for Mexico: +18138 cases (now 3.4 million), +649 deaths (now 261152), +48556 tests (now 9.9 million) since 23 hours ago — Egypt: +303 cases (now 289035), +12 deaths (now 16755) since a day ago — South Korea: +1709 cases (now 257110), +5 deaths (now 2308), +63167 tests (now 13.3 million) since 22 hours ago [... want %more?] | 04:30 |
| lastshell | https://www.nbcdfw.com/news/health/new-drug-shows-promise-as-covid-19-treatment/2733445/?amp | 04:53 |
| twomoon | nixonix can i ask you something privately? | 04:58 |
| Brainstorm | New from Eric Topol: @EricTopol: R to @EricTopol: Despite the lack of evidence, why did @joerogan and so many take Ivermectin? Remember the emergency podcast to "save the world"? And that it was "99 percent effective" and "the pandemic would end in a month" but it was being suppressed by a [... want %more?] → https://is.gd/akxQhf | 05:01 |
| twomoon | hay evidencia que una infeccion mas 'intensa' genera una mejor diversidad de antibodies? | 05:13 |
| Brainstorm | New from r/WorldNews: worldnews: Brazil's worst drought in almost a century is threatening electricity supply and critical crops, pushing up energy and food prices at a time the country was hoping to start recovering from the economic fallout of the coronavirus pandemic → https://is.gd/XrPj3D | 05:54 |
| Brainstorm | New from r/WorldNews: worldnews: Kim Jong-un rejects Covax vaccine offer as North Korea fights pandemic in ‘our style’ → https://is.gd/tXEa5R | 06:48 |
| Brainstorm | Updates for Grenada: +153 cases (now 817), +1 deaths (now 4) since 21 hours ago — Pakistan: +3787 cases (now 1.2 million), +57 deaths (now 26035), +59745 tests (now 17.9 million) since 23 hours ago — Germany: +21419 cases (now 4.0 million) since 23 hours ago — Belgium: +2204 cases (now 1.2 million), +10 deaths (now 25392), +88676 tests (now 18.8 million) since 16 hours ago | 06:59 |
| Brainstorm | New from r/WorldNews: worldnews: Cuba prepares to vaccinate its children, entire population → https://is.gd/lo19ZF | 07:19 |
| Brainstorm | New from Politico: Coronavirus: UK and Australia announce vaccine swap deal → https://is.gd/lA5Ii5 | 07:30 |
| Brainstorm | Updates for Pennsylvania, United States: +4585 cases (now 1.3 million), +90 deaths (now 28325) since 23 hours ago — Bavaria, Germany: +2869 cases (now 681809), +8 deaths (now 15428) since 23 hours ago — New South Wales, Australia: +1417 cases (now 30807), +12 deaths (now 173) since 23 hours ago — Lower Saxony, Germany: +1136 cases (now 280753), +2 deaths (now 5859) since 23 hours ago | 08:01 |
| Brainstorm | New from EMA: What's new: Medicine: Veterinary medicines European public assessment report (EPAR): ProteqFlu-Te, equine influenza (live recombinant) and tetanus vaccine, Date of authorisation: 06/03/2003, Revision: 16, Status: Authorised → https://is.gd/gGfA4Y | 08:33 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | September 03, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/U33iJr | 09:05 |
| Brainstorm | New from The Indian Express: World: Vaccines not an option, life for families with young children → https://is.gd/BPE1eS | 09:58 |
| Brainstorm | Updates for India: +45352 cases (now 32.9 million), +149 deaths (now 439610), +5959837 vaccines (now 515.6 million) since 17 hours ago — Lithuania: +828 cases (now 301167), +14 deaths (now 4593) since 23 hours ago — Czechia: +308 cases (now 1.7 million), +1 deaths (now 30405), +6893 vaccines (now 6.0 million), +110844 tests (now 36.2 million) since a day ago [... want %more?] | 10:30 |
| xrogaan | twomoon: I don't think so. | 10:36 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: ‘On the brink:’ Two-thirds of KY hospitals face critical shortages of staff, supplies → https://is.gd/Ca2bLx | 10:41 |
| xrogaan | twomoon: check the links of the episode: https://www.microbe.tv/twiv/twiv-799/ | 10:44 |
| twomoon | thanks bro | 10:47 |
| Brainstorm | New from StatNews: Opinion: STAT+: A 10-point plan for sustaining the biopharma industrial base for a more secure nation: The U.S. runs the risk of repeating mistakes made in responding to Covid-19 and prior epidemics if it does not institute systemic changes to the way the government works with… → https://is.gd/VOdSlK | 10:51 |
| Brainstorm | New from Politico: EU and AstraZeneca settle court case over vaccine supply: The agreement will probably have little impact on vaccination within Europe, as the EU will end up donating many of these doses. → https://is.gd/987f8H | 11:02 |
| Brainstorm | New from The Indian Express: World: Kim Jong Un orders tougher virus steps after N Korea shuns vaccines → https://is.gd/bIai0N | 11:23 |
| Brainstorm | New from BMJ: Why Taiwan approved its own vaccine before phase III trials: On 19 July 2021, Medigen Vaccine Biologics became the first local company to win emergency approval from Taiwan’s regulator for a covid-19 vaccine candidate.But the drug’s approval has sparked... → https://is.gd/3EDT24 | 11:34 |
| Brainstorm | New from r/WorldNews: worldnews: Kim Jong Un shuns vaccines to fight Covid North Korea 'style' → https://is.gd/suMwe4 | 11:55 |
| Brainstorm | New from The Indian Express (Health): Life-style: Trash to treasure: Thailand makes Covid-19 protective gear out of upcycled bottles → https://is.gd/yMkBOU | 12:06 |
| Brainstorm | New from The Indian Express: World: COVID surge in Southeast Asia disrupts global supply chains → https://is.gd/QXEVg4 | 12:16 |
| Brainstorm | New from The Indian Express: World: AstraZeneca reaches settlement with EU on COVID-19 vaccine delivery → https://is.gd/dFIwvz | 13:32 |
| Brainstorm | New from ECDC: ECDC awards 77 M€ to strengthen EU/EEA Member States’ capacities to detect and identify SARS-CoV-2 variants: ECDC has awarded more than 77 M€ to 24 EU/EEA countries to strengthen whole genome sequencing and RT-PCR infrastructures within the countries’ national public health programmes. → https://is.gd/KbvQXT | 13:42 |
| Brainstorm | New from ECDC: Data collection on COVID-19 outbreaks in closed settings with a completed vaccination programme: long-term care facilities: The main aim of this activity is to collect information on the severity of breakthrough COVID-19 infections in outbreaks at long-term care facilities (LTCFs) and to obtain a timely estimate of vaccine effectiveness [... want %more?] → https://is.gd/cUG6Ms | 14:04 |
| Brainstorm | New from BBC Health: Why vaccinating all teens is a difficult decision: Concerns over a very rare heart side-effect are giving vaccine experts pause for thought. → https://is.gd/0AJNRR | 14:25 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: Lawmakers ramp up probe of FDA approval of Biogen drug; EU to return J&J Covid-19 shots to Africa → https://is.gd/FOzDNi | 15:30 |
| Brainstorm | New from WebMD: Kidney Damage Another Consequence of 'Long COVID': Researchers found that months after initial infection, COVID survivors were at increased risk of various types of kidney damage -- from reduced kidney function to advanced kidney failure. → https://is.gd/wPfYyr | 16:13 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.08.18.21262237v1 | 16:40 |
| Brainstorm | de-facto: From www.medrxiv.org: Impact of Delta on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK | medRxiv | 16:40 |
| Brainstorm | New from BBC Health: Not enough benefit to offer all teens Covid jabs: But a larger group of 12-15 year olds with underlying conditions will get the vaccine. → https://is.gd/E6sDmJ | 16:46 |
| Brainstorm | New from Reddit (test): CoronavirusUK: JCVI not recommending vaccines for all 12 to 15-year-olds → https://is.gd/5H6zDz | 16:56 |
| Brainstorm | New from r/WorldNews: worldnews: Anti-vaxxers storm government building where Covid vaccine got green light → https://is.gd/oNbNCt | 17:07 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Kidney Outcomes in Long COVID ( https://www.zotero.org/groups/covid_links/items/WKCAS5IK ) | 17:18 | |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Cerebral venous thrombosis and portal vein thrombosis: A retrospective cohort study of 537,913 COVID-19 cases ( https://www.zotero.org/groups/covid_links/items/5WCKTSIW ) | 17:33 | |
| Brainstorm | New from Reddit (test): Friday 03 September 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/yWphQ5 | 17:39 |
| Brainstorm | New from Politico: UK committee: Healthy kids aged 12-15 don’t need coronavirus vaccine: The government has come under heavy fire for not rolling out vaccinations to kids over 12 in time for their return to school. → https://is.gd/ACIj86 | 18:00 |
| Brainstorm | New from Politico: EU, AstraZeneca declare a truce in vaccine delivery dispute: The agreement will probably have little impact on vaccination within Europe, as the EU will end up donating many of these doses. → https://is.gd/bmVYJS | 18:11 |
| pwr22 | Going to a stag party tomorrow | 18:15 |
| pwr22 | Chance of covid high I guess | 18:15 |
| Cashlin | maybe dont go definitely wear a mask even if ur vaxxed | 18:15 |
| pwr22 | I will be going and I'm unlikely to wear a mask all the time 🤷 | 18:16 |
| pwr22 | It is what it is - I'm going to take the risk | 18:16 |
| de-facto | take the risk, but make a test a few days later to know if you need to isolate or not | 18:20 |
| de-facto | also could make sense to take a test prior to participation | 18:21 |
| de-facto | i do that all the time, e.g. today went to haircut shop, although i am fully vaccinated i made a test prior to that (would not be required but i do what i think makes sense) | 18:22 |
| de-facto | and for the personal risk: be aware that Delta is contagious enough that you also can catch it outdoors, even when vaccinated | 18:25 |
| de-facto | risk of severe progression is significantly lowered by vaccination, but it never is void, its all about probabilistic statements about big cohorts, never about individuals | 18:26 |
| de-facto | if i would make a party i just would require everyone to make a test a few hours prior to participation, regardless of vaccination or recovery status | 18:32 |
| de-facto | if someone refuses i would refuse entry | 18:32 |
| Brainstorm | Updates for United Kingdom: +42065 cases (now 6.9 million), +1292523 tests (now 273.3 million) since 15 hours ago — Turkey: +23656 cases (now 6.4 million), +283 deaths (now 57283) since 16 hours ago — Philippines: +20084 cases (now 2.0 million), +193 deaths (now 33873), +88473 tests (now 19.0 million) since a day ago [... want %more?] | 18:35 |
| Cashlin | de-facto is smart, yeah if you get it and live you can still lose your sense of smell and get debilitating life long side effects that no one knows the full effect and scope of | 19:00 |
| Brainstorm | New from WebMD: Americans' COVID Medical Bills Are Set to Rise: COVID-19 care is likely to get more expensive for Americans with the expiration of insurers' temporary waivers on costs associated with treating the illness. → https://is.gd/vcZ8Ab | 19:05 |
| dTal | de-facto: what's the false negative rate on the lateral flow tests? I thought it was so high as to be useless for that purpose | 19:25 |
| dTal | Specifically, they only catch about half of asymptomatic cases | 19:26 |
| dTal | so widely distributing them might make a useful impact on R at a society-wide level, but at a personal, guaranteed-not-to-get-covid level they're not all that | 19:27 |
| dTal | they're not going to make the difference between a "safe" party and a "risky" one | 19:29 |
| dTal | https://www.microcovid.org/ is useful, and scary, for estimating risk | 19:29 |
| lapeste | .title https://www.menshealth.com/health/a37465976/joe-rogan-covid-treatment-ivermectin-doctor-mike-explains/ | 19:49 |
| Brainstorm | lapeste: From www.menshealth.com: Doctor Explains Why Joe Rogan's Covid Treatment Makes No Sense | 19:49 |
| Brainstorm | New from The Indian Express: World: Soaring COVID-19 infections restrain US job gains in August → https://is.gd/TB8uOU | 20:09 |
| de-facto | dTal, thats why i said a few hours in advance | 20:16 |
| de-facto | since lateral flow tests (rapid antigen tests) have a lower sensitivity than PCR tests they detect infections later in the initial exponential viral replication, hence have to be taken shorter before the participation | 20:17 |
| de-facto | ideal would be always PCR but its not always possible to do that, so instead test often and short time prior to the event, that also helps | 20:18 |
| de-facto | better than no test in any case | 20:18 |
| de-facto | the thing is, if someone would currently have a very high viral shedding load, hence could be source of a super spread, such rapid antigen tests *should* be able to detect that, if samples are taken properly and temperature range is correct etc | 20:20 |
| de-facto | there never will be a guarantee, false negatives will occur even with the best tests | 20:20 |
| de-facto | of course there will never be a "safe" party, but some measures can decrease the *probability* that it becomes a super spread event | 20:21 |
| de-facto | e.g. outdoors, testing, small controlled and closed cohort | 20:23 |
| de-facto | ideal would be to be able to book a service that provides on-site PCR tests for all participants | 20:24 |
| de-facto | but are we there yet? PCR test as a service on site? | 20:24 |
| trbp | who pays for all those tests? | 20:26 |
| Brainstorm | New from Eric Topol: @EricTopol: R to @EricTopol: The other @CDCgov report today in kids; impact of Delta and vaccinations in adolescents https://www.cdc.gov/mmwr/volumes/70/wr/mm7036e2.htm?s_cid=mm7036e2_w → https://is.gd/rlSNy4 | 20:31 |
| lapeste | "Lasse Lehtonen, Hus's director of diagnostics, does not consider home tests sold in the store to be a reliable way to ensure that he does not carry the coronavirus" | 20:34 |
| lapeste | It is not just a sage sample or a secretion sample, but should contain cells that contain the virus. That’s why it’s challenging. You should be able to scratch the mucous membranes enough for the cells to come off, Lehtonen says. When performing an official corona test, it is requested to prune before testing to obtain cells instead of a stick. | 20:34 |
| lapeste | The reality, of course, is that if a person wants a negative test result, it can be obtained just as easily if you put the tags on the hat and pulled from there. The probability of pulling a patch from a hat is in the same range as taking a home test. People practically always get a negative result. | 20:34 |
| lapeste | According to Lehtonen, there is a clear difference between antigen tests performed at home and antigen tests performed by professionals, the quality of which is strictly controlled according to health criteria. | 20:35 |
| lapeste | https://translate.google.com/translate?sl=fi&tl=en&u=https://www.is.fi/kotimaa/art-2000008238956.html | 20:36 |
| lapeste | maybe they will find new cases sometimes, but the problem is, people use them instead of getting to pcr test. then think they are clear, when theres a very high chance they are not | 20:37 |
| lapeste | "The CSIRO health director has urged Australians to strongly consider getting the AstraZeneca vaccine after a new study showed it was more effective than Pfizer. Dr Rob Grenfell said the vaccine had proven to last longer and offer better protection than its competitor based on the latest statistics from the UK. | 20:38 |
| lapeste | 'Remarkably, AstraZeneca was better. It actually performed better in reducing hospitalisations and deaths. And more importantly the immunity developed from the AstraZeneca appears to be longer than the Pfizer.' | 20:38 |
| lapeste | why im not aware of those claimed uk statistics. are there such, or did he just lie? | 20:39 |
| lapeste | especially for hospitalization. i checked uk govt stats. no such results. ic, ons, or some other instance, does anyone know? | 20:40 |
| LjL | what is this study that shows AstraZeneca is better? i did see that graph with AZ antibodies waning slower, but was that it? | 20:41 |
| lapeste | and that more lasting protection is just speculation based on that ab titer curve (pfizer was still ahead in it too, but az's curve was flatter. but CI's overlapped so, that it could actually be the other way around) | 20:41 |
| LjL | i don't know, the UK data tend to be pretty silent about vaccine vs vaccine | 20:41 |
| lapeste | yeah, ive noticed that... | 20:41 |
| LjL | there are some data, but they're biased in all sorts of ways since the vaccines weren't giving to similar cohorts. so unless someone makes a competent matched cohort study, they don't mean much | 20:42 |
| lapeste | .title https://www.gov.uk/government/publications/covid-19-vaccine-surveillance-report | 20:43 |
| Brainstorm | lapeste: From www.gov.uk: COVID-19 vaccine surveillance reports - GOV.UK | 20:43 |
| lapeste | .title https://www.bmj.com/content/374/bmj.n1960 good read | 20:43 |
| Brainstorm | lapeste: From www.bmj.com: Covid-19: How effective are vaccines against the delta variant? | The BMJ | 20:43 |
| lapeste | .title https://www.nytimes.com/2020/03/19/opinion/sunday/coronavirus-camus-plague.html | 20:44 |
| Brainstorm | lapeste: From www.nytimes.com: Opinion | Camus on the Coronavirus - The New York Times | 20:44 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.08.18.21262237v1 | 20:45 |
| Brainstorm | de-facto: From www.medrxiv.org: Impact of Delta on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK | medRxiv | 20:45 |
| de-facto | Table 2 page 25 | 20:47 |
| Brainstorm | New from CIDRAP: COVID-19 Scan for Sep 03, 2021: Vaccine protection against Delta Loss of taste, smell and COVID-19 Inmate release for COVID-19 → https://is.gd/wcHB0c | 20:52 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Impact of Delta on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK ( https://www.zotero.org/groups/covid_links/items/XKQEAUXJ ) | 20:53 | |
| de-facto | .title https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.35.2100793 | 20:55 |
| Brainstorm | de-facto: From www.eurosurveillance.org: Eurosurveillance | Vaccine effectiveness against infection with the Delta (B.1.617.2) variant, Norway, April to August 2021 | 20:55 |
| nixonix | what in the table? bnt looks better, but is az winning in something? i might have older version, since its downloaded before the date in the link | 20:56 |
| nixonix | or do you mean the last column - is that reinfections? | 20:57 |
| LjL | i see nothing showing AZ is better | 20:57 |
| nixonix | come on, whats there? point us to looking at the right information. reinfections are interesting tho | 20:59 |
| de-facto | i did not say AZ is better or such | 20:59 |
| de-facto | its just a study comparing the vaccines | 20:59 |
| nixonix | ok. but are those reinfections? | 21:00 |
| de-facto | the last column "Not vaccinated, previously positive*" yeah | 21:00 |
| nixonix | somewhat lower than in the danish study. maybe different period of variants tho | 21:01 |
| LjL | which would suggest previous infection doesn't necessarily help more than vaccines | 21:01 |
| de-facto | btw also a efficacy table on page 7 of https://www.gov.uk/government/publications/covid-19-vaccine-surveillance-report | 21:02 |
| nixonix | no it doesnt, althoug the hidden cases, share of them, might be different among reinf and vaxed | 21:02 |
| de-facto | still looks like BNT>AZ to me | 21:02 |
| LjL | same to me | 21:02 |
| LjL | but again these studies from the UK don't adjust things | 21:03 |
| nixonix | so we dont know for sure, exp that the study claiming over 10x better protection from infection than vax is incorrect. antivaxers using that, which is the shame, because simpletons now think its better to just get infected, so that you wouldnt get infected, sigh... | 21:03 |
| LjL | the raw data, i'm not qualified to interpret it | 21:03 |
| de-facto | previous infection looks pretty similar to only *one* dose of Moderna | 21:03 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Vaccine effectiveness against infection with the Delta (B.1.617.2) variant, Norway, April to August 2021 ( https://www.zotero.org/groups/covid_links/items/U4BP8XM2 ) | 21:03 | |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Covid-19: How effective are vaccines against the delta variant? ( https://www.zotero.org/groups/covid_links/items/3G9AE23W ) | 21:03 | |
| nixonix | infection sucks in multiple ways | 21:03 |
| nixonix | maybe it does some selection for traits tho | 21:04 |
| LjL | Among people with negative COVID-19 test results, loss of taste or smell was more strongly associated with congestion or runny nose compared with those who had positive test results (odds ratios [ORs], 2.26 vs 1.66). Similarly, loss of taste or smell was more strongly associated with cough and fever if the COVID-19 test was negative, not positive (ORs, 1.16 to 1.57 vs 0.95 to 1.01). | 21:09 |
| LjL | https://www.cidrap.umn.edu/news-perspective/2021/09/covid-19-scan-sep-03-2021 | 21:09 |
| LjL | not surprised about congestion, bit surprised about cough and fever | 21:09 |
| Brainstorm | New from StatNews: The White House wants $65 billion for an Apollo-style pandemic preparedness program: The Biden administration on Friday unveiled a sweeping, $65 billion proposal to remake the nation’s pandemic preparedness infrastructure in the wake of Covid-19. One adviser likened it to the Apollo… → https://is.gd/1SFF6C | 21:14 |
| nixonix | now some of our hc officials are running with RSV argument, that it takes more kids to hospital than sars2 (so letting sars burn through unvccinated kids is ok) | 21:20 |
| specing | Is it just me or are hc officials worried more about hospital bed space than long term issues? | 21:21 |
| nixonix | but true, surprisingly small numbers of kids needing hospital care and especially ICU, compared to some other countries. maybe its just the real infection numbers. for reasons like ventilation in schools, regional remote learning during high cases (exp during this delta period!) and stuff | 21:22 |
| nixonix | long term issues, only thing they are paying attention is those persistent symptoms. permanent brain or other organ damage doesnt exist, if you dont complain | 21:23 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: India’s DNA COVID vaccine is a world first – more are coming ( https://www.zotero.org/groups/covid_links/items/2IH67RPD ) | 21:23 | |
| nixonix | so the only thing that could change that, would be studies showing prevalence of those, and published in lancet, nature etc. and other countries start to worry first, foreign media getting loud on subject etc | 21:24 |
| LjL | for a change, there is no phase 3 paper out about ZyCov, and yet India just approved it | 21:25 |
| nixonix | does lancet work for you? site down? | 21:26 |
| LjL | doesn't work for me | 21:27 |
| nixonix | oh yeah, that dna plasmid vaccine, with springy system for skin inoculation | 21:27 |
| nixonix | wheres published phase 3 result? | 21:28 |
| LjL | nowhere? | 21:29 |
| nixonix | ABNCov2, some type of capsid vlp, i couldnt find much information on that another day. it was adjuvanted with squalene i think | 21:29 |
| nixonix | i was wondering if those harvested antigens somehow self-attach to nanoparticle, they cant possible glue them in sweatshop... it appears it uses glue, though | 21:30 |
| de-facto | .title https://www.whitehouse.gov/briefing-room/statements-releases/2021/09/03/fact-sheet-biden-administration-to-transform-capabilities-for-pandemic-preparedness/ | 21:30 |
| Brainstorm | de-facto: From www.whitehouse.gov: FACT SHEET: Biden Administration to Transform Capabilities for Pandemic Preparedness | The White House | 21:30 |
| de-facto | that makes a lot of sense, hope countries worldwide try to learn from what went wrong | 21:31 |
| nixonix | no english sources for use of glue, only finnish and apparently swedish where it was translated from - and prob danish. "With the help of a bacterial superglue developed by the researchers themselves, harmless virus molecules are glued to virus-like particles | 21:35 |
| nixonix | exp this, from translated article | 21:35 |
| nixonix | there are some articles on bacterial superglue use with nanoparticles | 21:36 |
| LjL | glue O.o | 21:36 |
| nixonix | .title https://www.nature.com/articles/s41467-020-20251-8 doesnt mention that vaccine, but prob people behind the design, since there are danish | 21:38 |
| Brainstorm | nixonix: From www.nature.com: Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity | Nature Communications | 21:38 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Biden wants $65 billion for 'Apollo'-style pandemic preparedness program ( https://www.zotero.org/groups/covid_links/items/IQ4EB2SZ ) | 21:38 | |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: On-the-Record Press Call by Office of Science and Technology Policy Director Dr. Eric Lander and NSC Director for Global Health Security and Biodefense Dr. Beth Cameron on American Pandemic Preparedness ( https://www.zotero.org/groups/covid_links/items/KI2783RI ) | 21:38 | |
| nixonix | global surveillance of virus sequences, studying vaccines for different types of viruses that could emerge. g-o-f studies with them. yeah i know... | 21:41 |
| nixonix | they say that more intereste in hcov vaccines would have helped. luckily there was some research going on with sars1, mers | 21:42 |
| LjL | someone yesterday said something about gof research in a BSL2 lab | 21:44 |
| nixonix | yeah, wastewater surveillance in big cities of the world | 21:44 |
| nixonix | .title https://twitter.com/ForesightWisdom/status/1433697186949255182 | 21:51 |
| Brainstorm | nixonix: From twitter.com: Foresight 👀, not Hopium 🤦♂️🔮🙈 (@ForesightWisdom): "Eran doesn't mention that are about 3000 ppl with Covid who are sitting at home with an oxygen generator from a public charity called "Yad Sarah". [...] | 21:51 |
| nixonix | .title https://twitter.com/EricTopol/status/1433627626749399080 podcast on vax hesitancy and stuff. prob many people like to listen to these, i prefer reading stuff (faster) | 21:54 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "I cited you and your Part 1 extensively in the podcast with @SamHarrisOrg which antedated the retraction of the Egypt trial https://samharris.org/podcasts/256-contagion-bad- [...] | 21:54 |
| nixonix | .title https://twitter.com/EricTopol/status/1433606986931662880 also a few more eric's posts in the thread on ivermectin, including links | 21:57 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "Not only has the data to support potential use of Ivermectin been exceptionally weak from small studies, but now 2 of the studies most cited have been shown to be fraudulent, [...] | 21:57 |
| nixonix | .title https://github.com/TheMemeticist/Cellular-Defense-Automata/tree/memeLab | 22:04 |
| Brainstorm | nixonix: From github.com: GitHub - TheMemeticist/Cellular-Defense-Automata at memeLab | 22:04 |
| Brainstorm | New from CIDRAP: Child COVID hospital cases up in low-vaccination states: Stephanie Soucheray | News Reporter | CIDRAP News Sep 03, 2021 The US surge has driven child COVID hospitalization rates to pandemic highs. → https://is.gd/6tcIU2 | 22:07 |
| nixonix | this seesm pretty comprehensive for medical acronyms: https://www.allacronyms.com/SAG/medical | 22:16 |
| nixonix | .title https://twitter.com/jacquesenboit/status/1433779099537842181 | 22:27 |
| Brainstorm | nixonix: From twitter.com: Jacquesenboit (@jacquesenboit): "The 2P substitution K986P/V987P is not part of the SAg (~675:685). IOW, in no way it disrupts the SAg. @EricTopol Dec'20 : [...] | 22:27 |
| Brainstorm | New from r/WorldNews: worldnews: The pandemic’s true death toll → https://is.gd/CFX9YI | 22:39 |
| Brainstorm | New from CIDRAP: mRNA COVID vaccines not tied to serious side effects: Mary Van Beusekom | News Writer | CIDRAP News Sep 03, 2021 None of the specified outcomes in 6.2 million vaccine recipients met the criteria for a safety signal. → https://is.gd/nVV8EX | 22:49 |
| nixonix | .title https://www.pnas.org/content/117/41/25254 i dont know how confirmed these areas are currently. but interesting read anyway (and i havent checked if PRRAR->RRRAR from P681R changes something) | 22:51 |
| Brainstorm | nixonix: From www.pnas.org: Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation | PNAS | 22:51 |
| nixonix | areas=ideas | 22:51 |
| LjL | https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates | 22:53 |
| LjL | "To fill in these voids in our understanding of the pandemic, The Economist has built a machine-learning model, which estimates excess deaths for every country on every day since the pandemic began. It is based both on official excess-mortality data and on more than 100 other statistical indicators. Our final tallies use governments’ official excess-death numbers whenever and wherever they are available, and the model’s estimates in all other cases. You | 22:54 |
| LjL | can read our methodology here, and inspect all our code, data, and models here." | 22:54 |
| LjL | here being https://github.com/TheEconomist/covid-19-the-economist-global-excess-deaths-model | 22:55 |
| nixonix | i just made a very rough estimate in my head another day, without checking confirmed case numbers at many regions, or trying to estimate the shaere of hidden cases on them, and i got 13.5M. thinkin that doing what i didnt, i would prob adjust it but thought id be within 10-20%. close to economists estimate | 22:55 |
| nixonix | estimate->estimation. two of those | 22:56 |
| nixonix | no estimate of fatalities due to mrna vax, in that article. i couldnt find those when i looked for. yeah, for old or otherwise fragile its often hard to say the reason, but other than that, heart thinga or allergy induced... they havent found any? | 23:02 |
| nixonix | anyways if you find something some day, link me | 23:03 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: The pandemic’s true death toll | The Economist ( https://www.zotero.org/groups/covid_links/items/P6DQJMF7 ) | 23:03 | |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1294200514566127622 year old, but leonardi just linked to it, good read the whole thread. afaik nothing in it is repealed yet, and some things have got more evidence | 23:14 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "2/CT scans still the most sensitive way to diagnose infection in asymptomatic people compared to a one-off PCR. Heart damage irrespective of symptoms. [...] | 23:14 |
| nixonix | .title https://www.researchsquare.com/article/rs-847396/v1 | 23:33 |
| Brainstorm | nixonix: From www.researchsquare.com: Correlates of Neutralizing/SARS-CoV-2-S1-binding Antibody Response with Adverse Effects and Immune Kinetics in BNT162b2-Vaccinated Individuals | Research Square | 23:33 |
| nixonix | what i recall from other studies, comparing them to qatar breakthrough times, it looked like 50% titeres somewhere below 150 and the protection for intection comes very weak (needs confirmation, if i recall that right) | 23:35 |
| nixonix | in that japanese study starting level for delta was 550, and vs beta (SA variant?) only 300 | 23:35 |
| nixonix | " The average half-life of NT50s was ~ 68 days" | 23:36 |
| nixonix | using that, around 4 months for delta to get under 150. and around 70 days for SA variant | 23:40 |
| nixonix | four months vaccine vs delta infection. two months vs SA variant infection | 23:41 |
| nixonix | maybe 2.5 | 23:41 |
| Brainstorm | New from Eric Topol: @EricTopol: How to lose public confidence?1. Announce a booster program on Sept 20 for all at 8 months post-vaccine2. Change it to 6 months, then 5 months, then back to 8 3. Lack of agreement among leadership group4. Have no US national data5. Announce the program will be "scaled back" → https://is.gd/OjmlFz | 23:43 |
| nixonix | that means, when especially those age and behavioral group that are the main drivers, are vaccinated 5 or more months ago, and vaccine coverage or otherwise gained immunity is high, SA variant or some other good immune evasion variant will take over delta, and starts spreading among vaccinated and recovered | 23:56 |
| nixonix | those vaccinated 5-6 months ago, the R vs SA variant would be around the same than those with no immunity vs uk. variant. couple months more, and its no better than no immunity at all | 23:58 |
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