| twomoon | oh.... | 00:01 |
|---|---|---|
| Brainstorm | New from Reddit (test): CoronaVirus_ITALIA: Francia: Hackerato il Green Pass di Macron e divulgato in Rete sui Social...Qualche giorno fa era toccato al premier Castex. → https://is.gd/IykV5f | 00:05 |
| twomoon | Hackerato il Green Pass di Macron e divulgato in Rete sui Social...Qualche giorno fa era toccato al premier Castex = ? | 00:17 |
| twomoon | i'm having trouble translating this using google | 00:17 |
| de-facto | huh whats the problem? | 00:22 |
| de-facto | %tr <it Hackerato il Green Pass di Macron e divulgato in Rete sui Social...Qualche giorno fa era toccato al premier Castex | 00:23 |
| de-facto | %tr <it Hackerato il Green Pass di Macron e divulgato in Rete sui Social...Qualche giorno fa era toccato al premier Castex | 00:23 |
| Brainstorm | de-facto, Italian to English: Macron's Green Pass hacked and spread on the Net on Social... A few days ago it was the turn of Prime Minister Castex (MyMemory) — Macron's Green Pass hacked and disclosed on Social Networks ... A few days ago it was the turn of Prime Minister Castex (Google) | 00:23 |
| twomoon | i don't know what 'era toccato al premier castex' means | 00:23 |
| twomoon | i don't think google is translating that correctly | 00:23 |
| de-facto | i guess it means few days ago same happened to premier Castex? | 00:25 |
| twomoon | yes, that must be it | 00:26 |
| imaginary | en español existe "le tocaba" y significa algo similar | 00:34 |
| imaginary | o "le toco" | 00:34 |
| twomoon | i am surprised that italian uses the "personal a" | 00:38 |
| twomoon | doesn't that seem odd to you? | 00:38 |
| twomoon | i thought italian didn't use that special 'a' | 00:38 |
| imaginary | i mean, if anything it'd be weird not to use it from our pov | 00:43 |
| imaginary | we are spanish speakers after all :x | 00:43 |
| twomoon | oh ok but ljl once said that 'a' is sacrilege or whatever the right word is | 00:44 |
| twomoon | totally weird | 00:44 |
| twomoon | so i'm wondering if i'm misinterpreting it now | 00:45 |
| imaginary | could also just be a regular 'a' and not a personal one | 00:47 |
| nixonix | there was quite a bit of expert discussion in several threads, about that recent leak (ecohealth, daszak etc), where role of furin site, spikes generally were discussed. because here some people were asking about furin etc, they are useful to read. like this one | 00:48 |
| nixonix | .title https://twitter.com/stuartjdneil/status/1439307787960467467 | 00:48 |
| Brainstorm | nixonix: From twitter.com: Stuart Neil (@stuartjdneil): "Except of course that nature has already shown the PRRAR to be suboptimal by selecting P-to-H and P-to-R changes at position 681 in the alpha, delta and mu. All of which [...] | 00:48 |
| imaginary | twomoon: i jsut realized this conversation was happening in the covid channel and not the spanish one, my b | 00:49 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1440142698929745929 | 00:50 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "I'm going to make a layperson translation of this. Before Cov 2's Pandemic, an entity applied for DARPA funding where they would insert the very same [...] | 00:50 |
| nixonix | a finnish virolog claimed in colomobia and ecuador a third and fifth of new infections are mu variant. they dont have recent sequencing data from those countries in outbreak, so maybe he has more information. but probably spotty data and not reliable | 00:54 |
| nixonix | and didnt think it could replace delta's dominance | 00:54 |
| nixonix | virologist | 00:55 |
| nixonix | there could be micro-rna drugs some day, that would silence some genes of viruses post-transcription, like those deletions in orf8 in that paper, making it milder or even deactivate the virions | 00:58 |
| de-facto | wouldnt that depend on seroprevalence and by what type of s-protein it was induced which variant gets more selected by evasion and breakthrough? | 00:59 |
| LjL-Matrix | twomoon: that's not "personal a", that's when you use it for a direct object | 00:59 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): It's 2021, yet we have analog vaccine cards that are easily counterfeited. @DrTomFrieden lays out what a national vaccine certification program should look like @nytopinion nytimes.com/2021/09/21/opi… → https://is.gd/mNBqzc | 00:59 |
| LjL-Matrix | I greet you becoming I greet to you | 00:59 |
| nixonix | funny how evolution caused something like that to develop in viruses. probably some short leftover snippets first, then by a chance, some day some of them were useful for the virus increasing immune evasion or something | 01:00 |
| LjL-Matrix | But le tocó is like "it happened to him" (not same meaning but same type of construction), you have "to" in the English one as well | 01:00 |
| LjL-Matrix | imaginary: but no, twomoon is right, it's not weird not to use it, it's weird af to use it, objectively | 01:01 |
| de-facto | yeah SARS-CoV-2 got some micro-RNA to suppress cellular mRNA so it can hijack the full cellular production capacity for its own proteins | 01:01 |
| de-facto | among other functions, i think those NSPs deserve more attention as they probably control a lot of reproduction number (on cellular level) once a virion entered a cell | 01:02 |
| de-facto | and if one cell is able to produce hundrets to thousands of virions it would be quite a relevant control mechanism | 01:03 |
| de-facto | also fidelity etc | 01:03 |
| nixonix | somebody wondered in those discussions, if the furin gets used when it steals a few atoms from furin site (if i recall) and breaks the convalent bond. didnt see if somebody answered, but probably. doesnt matter, those used furin molecules will be recycled and enough more will be produced from the remains apparently, since lack of furin doesnt seem | 01:03 |
| nixonix | to slow delta | 01:03 |
| LjL-Matrix | de-facto: it worries so much that they frame this as "his green pass was hacked". His green pass was... photographed, that's all. The message that the green pass must be secret is wrong, the green pass is meant to be used together with ID, and thinking otherwise will lead to lame excuses to justify obnoxious phone features like SafetyNet and mandatory apps to display the green pass instead if just using whatever can display a qr code for you | 01:03 |
| LjL-Matrix | twomoon: and yes, "it was the turn of" is a pretty reasonable English translation of "era toccato a" given English doesn't have quite that expression | 01:05 |
| LjL-Matrix | Okay these are my contributions for tonight bye now I'll get drunk | 01:05 |
| nixonix | when the generation cap isnt decades but microseconds, theres lots of trial and error, and survival of the fittest. a third hand would be handy? no? how about four? we never had enough time to try it in mammals, i think... | 01:05 |
| nixonix | gap | 01:06 |
| de-facto | hmm so the headlines are exaggerated then, i would have understood "hacked" as gaining the ability to use a system in malicious ways such as signing a fake cert or such, but if its only a photograph of the QR code it is completely irrelevant | 01:06 |
| de-facto | everyone knows the full name and date of birth of those ministers anyhow | 01:07 |
| imaginary | LjL-Matrix: no u | 01:07 |
| LjL | de-facto, they may have "hacked" it, i haven't heard/read about this event, but i'm extrapolating based on talk there was in italy of people using other people's green pass and that you should keep it to yourself to avoid having it "hacked" | 01:08 |
| LjL | imaginary, you mean "no @ u" | 01:09 |
| de-facto | yeah, in my experience here noone controls the validity of the QR code anyhow, so basically i could print out any sample QR code and use it (except i would risking getting into serious trouble (maybe even jail) if they control it one day) | 01:10 |
| LjL | generally speaking, when you see LjL-Matrix speak instead of me, you can assume i'm either half-reading with just one eye opening, or crossing the street while looking at my phone | 01:10 |
| LjL | (when it's 1am the former is more likely) | 01:10 |
| LjL | de-facto, yes, and i guess it's not surprising that they do it like that in many circumstances, but we must keep in mind it's kind of an "informal" use of it and not the way it's *meant* to be used | 01:11 |
| LjL | instead with terms like "hacked" for simply having a copy, you encourage people to think that's the normal and correct way | 01:11 |
| de-facto | yeah people should get used to control those, otherwise we dont need QR codes | 01:13 |
| de-facto | anyhow i am not convinced about all this vaccination passport thing, instead we should establish more testing | 01:16 |
| dTal | what's actually the point of the vaccine passport? | 01:17 |
| nixonix | reduce spreading and get more people to get a jab | 01:18 |
| dTal | seems to me it's mostly about the illusion of control | 01:18 |
| de-facto | yeah but imho it should not replace testing | 01:18 |
| dTal | You know my boss flew to Lithuania the other day | 01:18 |
| dTal | mandatory covid testing on arrival | 01:19 |
| de-facto | thats very good | 01:19 |
| dTal | no it ain't | 01:19 |
| dTal | apparently the procedure there is they drip 15 drips on a lateral flow test instead of the usual 2, wait 15 seconds, then call it negative and chuck it in the bin | 01:19 |
| dTal | complete theatre | 01:19 |
| de-facto | ahm what? | 01:20 |
| dTal | miraculously, no positive results with that procedure, in a queue with hundreds of people | 01:20 |
| dTal | imagine that | 01:20 |
| de-facto | that indeed does not sound good, they should use PCR | 01:20 |
| dTal | my boss got a certificate and everything | 01:21 |
| dTal | PCR!? and somehow house hundreds of people for many days? | 01:21 |
| dTal | isolating? | 01:21 |
| de-facto | lateral flow tests need 15 minutes in the right temp range | 01:21 |
| dTal | the ones we get here say half an hour, in no uncertain terms | 01:22 |
| de-facto | and PCR maybe three times that, if done at site | 01:22 |
| dTal | but it sounds like they were doing it like passport control | 01:22 |
| de-facto | they should not be able to issue a cert then if they do it incorrectly | 01:23 |
| dTal | indeed, but there's no authority to say that | 01:24 |
| nixonix | its just for show. what they really want, is mass infection of kids (ive been reading irene tosetti... | 01:24 |
| dTal | never heard of her but boy she got dem crazy eyes, according to google | 01:27 |
| nixonix | .title https://twitter.com/itosettiMD_MBA/status/1437883897128304649 | 01:28 |
| Brainstorm | nixonix, the URL could not be loaded | 01:28 |
| Brainstorm | Updates for Anguilla: +1 deaths (now 1) since 17 hours ago | 01:29 |
| de-facto | imho vaccination is for introducing the immune system to s-protein hence protection against (symptomatic infections) and even more against severe progressions, meaning personal protection and taking load from healthcare system, (proper) testing can end infection chains by preventing more spreading and also allows for monitoring breakthrough rates (important to estimate vaccination efficacy) | 01:29 |
| -Bridgestorm- ⭕ Earthquake! 6.0 Mlv tremor, registered by alomax,scevent, with 33 reports, 31 early, occurred 14 minutes ago (23:15:55 UTC), during daytime, Near S.E. Coast Of Australia (-37.46, 146.37) ± 1 km, ↓11 km likely felt 230 km away (in Melbourne…) by 5.4 million people — Webcams: https://www.windy.com/webcams/1216174612 https://www.windy.com/webcams/1618543217 https://www.windy.com/webcams/1431412855 (service.geonet.org.nz) | 01:30 | |
| -Bridgestorm- ⭕ Earthquake! 6.2 Mb tremor, registered by alomax,scevent, with 33 reports, 33 early, occurred 14 minutes ago (23:15:55 UTC), during daytime, Near S.E. Coast Of Australia (-37.46, 146.39), ↓5 km likely felt 240 km away (in Melbourne…) by 5.4 million people — Webcams: https://www.windy.com/webcams/1216174612 https://www.windy.com/webcams/1618543217 https://www.windy.com/webcams/1431412855 (quakesearch.geonet.org.nz) | 01:30 | |
| dTal | quick question, why do we get earthquake notifications here | 01:30 |
| nixonix | and its to lessen the chances to infect other people, who then can infect more and after some time: | 01:31 |
| nixonix | .title https://www.nbcboston.com/news/coronavirus/biogen-conference-in-boston-now-tied-to-more-than-300000-coronavirus-cases/2254941/ | 01:31 |
| Brainstorm | nixonix: From www.nbcboston.com: Biogen Conference in Boston Linked to More Than 300,000 COVID-19 Cases, Science Journal Study Suggests – NBC Boston | 01:31 |
| nixonix | we discussed about that in april 2020 or so, check from logs | 01:41 |
| nixonix | there are regions in usa with over 95% vax coverage of 12+. with population of tens of thousands. i doubt we have here | 01:41 |
| nixonix | .title https://twitter.com/Cascadia/status/1440357475601903625 | 01:44 |
| Brainstorm | nixonix: From twitter.com: Sherry Reynolds 🌟 (@Cascadia): "In one Seattle suburbs (Bellevue is majority minority and 38% foreign born) they have 95% vaccination rates and zero deaths in last 14 days." | nitter | 01:44 |
| Brainstorm | Updates for Mayotte: +3 cases (now 20179) since 2 days ago — Fr. Polynesia: +3 deaths (now 602) since 20 hours ago | 02:06 |
| Brainstorm | New from BBC Health: Covid vaccine stockpiles: Are 241m doses at risk of going to waste?: Joe Biden wants more global vaccine equality but the US and other nations have not backed promises with action. → https://is.gd/W8BzzU | 02:13 |
| Brainstorm | Updates for United Kingdom: +24479 cases (now 7.5 million), +44 deaths (now 135522) since 21 hours ago — Martinique: +306 cases (now 40545), +10740 tests (now 359082) since 18 hours ago | 02:31 |
| Brainstorm | Updates for Congo: +313 cases (now 14014), +8 deaths (now 191) since 2 days ago | 03:09 |
| Brainstorm | New from r/WorldNews: worldnews: Canadian voters angry for ''pointless mid-pandemic'' election : ''We have a $600-million bill to pay, with nothing to show for it'' → https://is.gd/HG9dtN | 03:38 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): The benefit of long spacing of Pfizer vaccine to 16-weeks for an immune response comparable to prior Covid + 1-dose vaccine, with assessment vs Delta and other major variants medrxiv.org/content/10.110… pic.twitter.com/OjSziffpDy → https://is.gd/p6HKaF | 03:49 |
| Brainstorm | New from r/WorldNews: worldnews: Brazil’s unvaccinated president had to eat pizza on NYC sidewalk → https://is.gd/HMEyYe | 04:00 |
| Brainstorm | New from Politico: Certification and standards: Unions urge Westminster mask clampdown as MPs catch coronavirus → https://is.gd/C57xJA | 04:10 |
| Brainstorm | Updates for Channel Islands: +33 cases (now 11368), +29284 tests (now 901323) since a day ago | 04:11 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): 5. The variables associated with breakthrough hospitalizationsMost notable: Prior covid + vaccine marked protection pic.twitter.com/NFD3nT6LZf → https://is.gd/FywGm0 | 04:43 |
| Brainstorm | Updates for United Kingdom: +32370 cases (now 7.5 million), +95 deaths (now 135573) since 23 hours ago — South Korea: +1720 cases (now 290983), +6 deaths (now 2419), +31151 tests (now 14.1 million) since 23 hours ago | 05:01 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): As far as I know, this is the largest dataset of vaccinated Americans for breakthrough hospitalizations, w/ data several months out from getting vaccinated, multiple weeks into the 4th Delta wave (with the caveats of an insurance claims resource) → https://is.gd/LHdKdP | 05:05 |
| Brainstorm | New from Reddit (test): China_Flu: Study - Antiandrogens Reduce COVID Hospitalization, Deaths, And Disease Progression (Dr. Syed) → https://is.gd/9Vi11F | 05:15 |
| LjL | dTal, because big earthquakes impacting many people may have effects on lockdowns and quarantines and containment and COVID procedures in general | 05:23 |
| LjL | and that Australia earthquake was definitely unusual and i'm getting a slew of comments on Reddit about it | 05:23 |
| twomoon | why does 'a' get used for direct objects ljl ? | 05:30 |
| twomoon | isn't that a bit odd? i thought you said 'a' never gets used for direct objects in italian. | 05:30 |
| LjL | probably because with human objects (which is what it gets used for, or sometimes personalized animals" it feels more like you're doing an action "to" them, as they're conscious, rather than directly operating "on" them. and there is already a lot of "a" used for what english calls indirect objects, when verbs involve people: i talk TO you, the difference between "i talk to you about something" and "i talk you about doing something" is subtle, you're still talking | 05:33 |
| LjL | to the person | 05:33 |
| LjL | in italian we call direct objects "complemento oggetto" and indirect objects "complemento di termine". you can probably understand these terms. in one, you're acting on something, in the other, your action as "terminal" effect on something, or, often, someone | 05:35 |
| LjL | even in some southern italian dialects or just colloquial speech from those regions "a" is sometimes used the way spanish does | 05:35 |
| LjL | "i shoot you" sounds like a direct object in english (although with english it's kind of hard to tell, but you can tell because "i shoot to you" would be ungrammatical), but in italian "ti sparo" expands to "sparo a te". i.e. i shoot at you, in your direction. the meaning is the same as "i shoot you", but in one language you're the direct object of being shot, in the other you are the person the action acts on, terminates on | 05:36 |
| * LjL sleeps now | 05:37 | |
| twomoon | thanks ljl | 05:37 |
| twomoon | sorry to bug you once again | 05:37 |
| Brainstorm | New from r/WorldNews: worldnews: EU states breached air pollution limits in 2020 despite COVID → https://is.gd/Z3cqPV | 07:01 |
| Brainstorm | Updates for India: +283 cases (now 33.5 million), +1718565 tests (now 556.8 million) since 22 hours ago | 07:05 |
| Brainstorm | Updates for New Caledonia, France: +793 cases (now 4396), +8 deaths (now 33) since 23 hours ago — United Kingdom: +31182 cases (now 7.5 million), +146 deaths (now 135624) since 23 hours ago — Northwest Territories, Canada: +85 cases (now 834), +1 deaths (now 2) since 2 days ago — Belgium: +1797 cases (now 1.2 million), +7 deaths (now 25524) since a day ago | 07:30 |
| Brainstorm | New from The Indian Express: World: India’s decision to resume Covid-19 vaccine shipments important development: WHO chief → https://is.gd/RYY1xi | 07:33 |
| Brainstorm | New from The Indian Express: World: Coronavirus vaccine: Johnson & Johnson says second shot boosts protection → https://is.gd/Q88M6W | 08:05 |
| Brainstorm | New from The Indian Express: World: ‘Soul-crushing’: US COVID-19 deaths are topping 1,900 a day → https://is.gd/FiuqNX | 08:48 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | September 22, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/gjsi3M | 09:09 |
| Brainstorm | New from The Indian Express: World: Brazil’s unvaccinated President Bolsonaro eats pizza for dinner on New York street → https://is.gd/3AQ6Xs | 09:20 |
| Brainstorm | New from COVID tweets: Prof Francois Balloux (@BallouxFrancois): This is incorrect. The grant proposed to vaccinate bats against Sarbecoviruses, not to release 'airborne coronaviruses'. The idea was largely similar to vaccinating wildlife (foxes, coyotes, raccoons, ...) against rabies, which is effective in reducing human spillover cases. twitter.com/R_H_Ebright/st… → https://is.gd/2DRb8Z | 09:30 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): Waar veel niet-gevaccineerden wonen, tiert corona weliger standaard.be/cnt/DMF2021092… pic.twitter.com/xEiMfbpElS → https://is.gd/2r98Ho | 09:40 |
| Brainstorm | New from The Indian Express: World: COVID-19 sends northern Chinese city into semi-shutdown → https://is.gd/PLlEHF | 09:51 |
| Brainstorm | Updates for New Caledonia: +331 cases (now 4727) since a day ago | 09:59 |
| Brainstorm | New from The Indian Express: World: ‘I just cry all the time’: Non-Covid patients despair over delayed care → https://is.gd/j5pGvz | 10:02 |
| Brainstorm | Updates for Saint Lucia: +87 cases (now 10727), +18 deaths (now 168), +151 vaccines (now 43582), +281 tests (now 77248) since 8 hours ago | 10:36 |
| Brainstorm | New from StatNews: Opinion: Do we need vaccine exemption boards?: Like with draft boards during the Vietnam War, local or state vaccine boards could consider individual requests for exemptions, whatever the reason given. → https://is.gd/mnpLTJ | 10:44 |
| Brainstorm | Updates for Burundi: +2167 cases (now 16356) since 3 days ago — Germany: +7247 cases (now 4.2 million) since 23 hours ago | 11:01 |
| Brainstorm | New from BBC Health: Covid: People are vaccinated - so why are there so many cases?: More than four out of five UK adults are now fully vaccinated, but daily case rates remain high. → https://is.gd/zEPKnU | 11:05 |
| Brainstorm | New from ProPublica: Facebook Grew Marketplace to 1 Billion Users. Now Scammers Are Using It to Target People Around the World.: by Craig Silverman , A.C. Thompson and Peter Elkind ] ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. For years, Carman Alfonsi [... want %more?] → https://is.gd/vV5lwc | 11:16 |
| Brainstorm | New from r/WorldNews: worldnews: Vaccinated individuals now account for over half of new deaths in Israel → https://is.gd/SS9nk4 | 11:27 |
| xrogaan | >> Covid: People are vaccinated - so why are there so many cases? | 11:31 |
| xrogaan | Because that's the wrong metric. You need to look at how many people are dying, not the amount of cases. | 11:32 |
| xrogaan | It's like during WWI. They started to distribute hard hats to the soldiers, and a high graded (general?) seeing the increase in non-fatal casualties stated that the hats didn't work. Failed to recognize that the people who are then alive wouldn't have been if it weren't for the hats. | 11:34 |
| Brainstorm | New from The Indian Express (Health): Food & Wine: Young children’s diets ‘could get much worse’ under Covid: Unicef report → https://is.gd/z49PMe | 11:38 |
| Brainstorm | Updates for Russia: +19706 cases (now 7.3 million), +817 deaths (now 200625), +352095 tests (now 187.7 million) since a day ago — Cyprus: +248 cases (now 117483), +1 deaths (now 548), +2668294 tests (now 9.4 million) since a day ago | 12:03 |
| Brainstorm | New from BioNTech: Pfizer and BioNTech Expand Collaboration with U.S. to Provide 500 Million Additional COVID-19 Vaccine Doses at Not-For-Profit Price for Donation to Poorest Countries: Expanded agreement brings the total number of COVID-19 vaccine doses to be supplied to the U.S. government for donation to one billion Effort contributes to [... want %more?] → https://is.gd/IW6VVs | 12:10 |
| -Bridgestorm- ⭕ Sismo! Earthquake! 6.5 Mw tremor, registered by EMSC,US, occurred 22 minutes ago (09:57:08 UTC), with a gibbous moon, Near Coast Of Nicaragua (12.16, -87.82) ± 3 km, ↓32 km likely felt 380 km away (in Chinandega, León…) by 284900 people (www.seismicportal.eu) | 12:19 | |
| Brainstorm | New from r/WorldNews: worldnews: The U.S. Is Buying 500 Million More Pfizer Vaccine Doses To Donate To Other Countries → https://is.gd/wkJuzG | 12:32 |
| Brainstorm | Updates for Finland: +477 cases (now 137594), +20206 tests (now 7.0 million) since 23 hours ago | 12:41 |
| ViRoN | Updates for Belgium : +1797 cases (now 1.23M) 7-day avg: 2082 | 12:49 |
| Brainstorm | New from The Indian Express (Health): Health: Is Covid-19 associated with acute weight loss and malnutrition? Here’s what you need to know → https://is.gd/ppeFJQ | 13:15 |
| Brainstorm | New from The Indian Express: World: UNGA: Brazil’s health minister tests positive for Covid-19 in New York → https://is.gd/urGoup | 13:26 |
| Brainstorm | Updates for Romania: +7045 cases (now 1.2 million), +130 deaths (now 35851), +53951 tests (now 12.4 million) since 23 hours ago — Latvia: +674 cases (now 151917), +4 deaths (now 2662), +27216 tests (now 4.2 million) since a day ago — Senegal: +1 deaths (now 1849), +1908 tests (now 786849) since 23 hours ago | 13:30 |
| Brainstorm | New from Science-Based Medicine: Chipping Away at Vaccine Hesitancy: How to persuade the remaining unvaccinated. The post first appeared on Science-Based Medicine . → https://is.gd/tajMcM | 14:19 |
| specing | > how to | 14:31 |
| specing | ez | 14:31 |
| specing | if they had just listened for a moment to the reasons why they don't want to get vaccinated | 14:31 |
| specing | and fixed them | 14:31 |
| specing | because most are easily fixable | 14:31 |
| Brainstorm | Updates for Switzerland: +1048 cases (now 828981), +39034 tests (now 10.5 million) since 23 hours ago | 14:32 |
| specing | this covid thing is honestly a tragedy-comedy now | 14:39 |
| specing | I don't usually link stuff from GAFAM, but anyway https://www.youtube.com/watch?v=cXTGgup_Yto | 14:40 |
| Brainstorm | New from StatNews: Remdesivir reduces Covid hospitalizations when given early, study shows: Gilead’s Covid-19 drug remdesivir appeared to reduce hospitalizations by 87% in high-risk patients diagnosed early in the disease in a new study, the company said. → https://is.gd/81PGHw | 14:41 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: California now has nation's lowest virus transmission rate → https://is.gd/fIwDn2 | 14:52 |
| Brainstorm | Updates for Nepal: +1251 cases (now 787828), +6 deaths (now 11059), +11067 tests (now 4.1 million) since a day ago | 15:10 |
| Brainstorm | New from Contagion Live: COVID-19 Vaccination Declared Safe and Effective for Cancer Patients: Patients with cancer now have official confirmation that vaccinating against COVID-19 will protect them from contracting the virus. → https://is.gd/FzoZgW | 15:14 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): This surge in Singapore may be a harbinger of a positive future scenario when a country has 80% of their total population vaccinated: 98% of >13,000 cases were asymptomatic or mild pic.twitter.com/10B6zzw2xn → https://is.gd/7Jm66M | 15:25 |
| Brainstorm | Updates for Brunei: +201 cases (now 5586), +2 deaths (now 31), +5195 tests (now 317241) since a day ago | 15:59 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Some progress on the global vaccination missionwashingtonpost.com/opinions/2021/… by @JeffreyZients and @AnthonyBlinken1 @PostOpinions ft.com/content/f0bf29… @FT @donatopmancini @JamieSmythF Several more billion doses needed ASAP for LMIC and especially Africa pic.twitter.com/2g3Iy6kR5l → https://is.gd/rBQGxV | 16:09 |
| Brainstorm | Updates for Bangladesh: +1376 cases (now 1.5 million), +36 deaths (now 27313) since 22 hours ago — Fiji: +311 cases (now 50270), +13 deaths (now 579), +4911 tests (now 402792) since 2 days ago — Zambia: +77 cases (now 208676), +6769 tests (now 2.4 million) since a day ago — Gibraltar: +7 cases (now 5490), +976 tests (now 354553) since 23 hours ago | 16:31 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): COVID-19 Vaccine Janssen, COVID-19 vaccine (Ad26.COV2-S [recombinant]), COVID-19 virus infection, Date of authorisation: 11/03/2021, Revision: 8, Status: Authorised → https://is.gd/leysw6 | 16:31 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): On the waning impact of @moderna_tx vaccination over time: people who got their vaccination earlier (e column) had less protection than more recent (p column) in the US Delta wave medrxiv.org/content/10.110… pic.twitter.com/mI7J2kMjUz → https://is.gd/r2ACHv | 16:53 |
| Brainstorm | Updates for Germany: +7251 cases (now 4.2 million) since 23 hours ago | 17:02 |
| Brainstorm | New from ClinicalTrials.gov: (news): COVID-19 Antibody Responses in Cystic Fibrosis → https://is.gd/XWkPxC | 17:15 |
| Brainstorm | New from ClinicalTrials.gov: (news): Examine the Psychosocial Impacts of Covid-19 Pandemic. → https://is.gd/C1Sdck | 17:26 |
| pwr22 | https://www.bbc.co.uk/news/science-environment-58628689 | 17:29 |
| pwr22 | That's interesting | 17:29 |
| Brainstorm | New from ClinicalTrials.gov: (news): The South African Coronavirus Disease of 2019 (COVID-19) Surgical Outcomes Study → https://is.gd/JHxjsB | 17:37 |
| Brainstorm | Updates for Chile: +524 cases (now 1.6 million), +5 deaths (now 37379), +43427 tests (now 21.3 million) since a day ago | 17:39 |
| nixonix | Moderna COVID-19 Vaccine Update September 15th, 2021 - pdf file https://investors.modernatx.com/static-files/4826b212-0777-4b17-852e-0f32ca42bc92 | 17:45 |
| pwr22 | nixonix: I thought that was talking about an updated vaccine for a second ☹️ | 17:46 |
| nixonix | Moderna Highlights New Clinical Data on its COVID-19 Vaccine September 15, 2021 - pdf file https://investors.modernatx.com/node/12856/pdf | 17:46 |
| pwr22 | > In a prospective cohort study at Kaiser... (full message at https://libera.ems.host/_matrix/media/r0/download/libera.chat/8ad082dba63bed6497fdbf741916c12575217352) | 17:47 |
| pwr22 | That seems unlikely | 17:47 |
| nixonix | no, comparing the efficacy drop around 10 moths vs 5 months or so after the 2nd dose (huge confidence intervals with severe and deaths, though) | 17:47 |
| Brainstorm | New from ClinicalTrials.gov: (news): Music for Decreasing Dental Anxiety During Oral Surgery in Coronavirus Disease 2019 (COVID-19) → https://is.gd/AmN5nM | 17:48 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.09.17.21263624v1 | 17:48 |
| Brainstorm | nixonix: From www.medrxiv.org: Covid-19 in the Phase 3 Trial of mRNA-1273 During the Delta-variant Surge | medRxiv | 17:48 |
| pwr22 | whats mRNA-1273? | 17:49 |
| nixonix | .title https://investors.modernatx.com/news-releases/news-release-details/moderna-highlights-new-clinical-data-its-covid-19-vaccine/ | 17:49 |
| Brainstorm | nixonix: From investors.modernatx.com: Moderna Highlights New Clinical Data on its COVID-19 Vaccine | Moderna, Inc. | 17:49 |
| nixonix | vaccine, that normal moderna ronavax | 17:49 |
| pwr22 | Ah | 17:49 |
| nixonix | e and p in the end means e was the non-placebo group that got the vax in the fall, p was then in placebo arm, and got vaxed in jan-march mostly | 17:50 |
| nixonix | i estimated the they had around 10 months and 5 months on average from 2nd dose to the infection in the summer, in that comparison and study | 17:51 |
| nixonix | the=that | 17:51 |
| nixonix | https://investors.modernatx.com/news-releases/ | 17:51 |
| * pwr22 uploaded an image: (155KiB) < https://libera.ems.host/_matrix/media/r0/download/shortestpath.dev/PaxrujKQAkVndlOBqWhQHXqi/image.png > | 17:52 | |
| nixonix | that first pdf file, i couldnt find the web page where pdf files like that one were listed for download, just that pdf link. tell me if you find the right web page for future checking | 17:52 |
| pwr22 | Wait, so they think their third booster is going to increase immunity nearly 200% over the peak from the earlier shots | 17:53 |
| pwr22 | There's more to immunity than just serum antibody titres too 🤦♂️ | 17:53 |
| pwr22 | I know they're easy to measure but at this point they're starting to become a bit less useful | 17:53 |
| pwr22 | There's also the case of "Anti-bodies that work how well against what strains?" | 17:54 |
| pwr22 | I hear the monolithic term "anti-body" titres a lot | 17:54 |
| pwr22 | I wonder if the market / analysts are smart enough to see though this suspect investors deck 😀 ? | 17:56 |
| nixonix | yeah and theres more than just circulating neut ab titers too, from memory b-cells and bone marrow plasma cells, and the maturating, breadth, polyclonality... | 17:57 |
| Brainstorm | New from ClinicalTrials.gov: (news): Association of the Neutrophil/Lymphocyte Ratio With Pulmonary Complications and Mortality in COVID-19 Patients → https://is.gd/PslzZF | 17:59 |
| nixonix | while maturating depends on follicular t-cells recruited to germinal centers, and thus if the vaccine induces right cytokines for that, it prob also depend how low the circulating ab titers have waned before the next shot (or infection) | 17:59 |
| nixonix | so when moderna with 100mcg dose has 4 weeks standard dose interval, while its a bit longer than pfizer's, their titers are supposedly perhaps 2x pfizers, so they havent waned as low in 4 weeks, as pfizer's in 3 weeks | 18:00 |
| nixonix | so while moderna's circulating titers may still be higher than pfizer's, after like 5 months, its possible that pfizer's germinal center b-cells have maturated more because of that, so when the protection might be better for moderna at 6 months or so, but that may well reverse after more time has passed | 18:02 |
| nixonix | or become more even anyway. vs severe especially, when the circulating titers have gone too low to protect much vs infection | 18:02 |
| nixonix | so for moderna, even longer dose interval would be better than for pfizer, probably | 18:03 |
| nixonix | remembering their neut intervals have never been compared in the same study. only binding ab titers | 18:03 |
| Brainstorm | Updates for United Kingdom: +21584 cases (now 7.5 million), +1011639 tests (now 294.9 million) since 21 hours ago | 18:04 |
| nixonix | *neut ab titers | 18:04 |
| nixonix | *neut ab titers havent been compared in the same study. binding ab titers have been compared | 18:04 |
| nixonix | .title https://twitter.com/EricTopol/status/1440506149095100430/photo/1 here we see, that moderna (with 4 weeks standard dose interval) seems to give only couple of weeks advantage vs identified infection, vs pfizer with 3w | 18:07 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "2. No significant difference of waning for Pfizer vs Moderna for protection from breakthrough infections" | El Pajarito de NoGAFAM | 18:07 |
| nixonix | but its raw data, not stratified by age. and those getting moderna or pfizer are not necessarily comparable groups in some other ways either (like here they used moderna earlier in the far north lapland because easier cold chain) | 18:10 |
| nixonix | .title https://www.humetrix.com/powerpoint-vaccine.html damn slides, tell me if you cand dl those as a pdf or something | 18:11 |
| Brainstorm | nixonix: From www.humetrix.com: Waning Effect of COVID Vaccine | 18:11 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.09.17.21263532v1 | 18:14 |
| Brainstorm | nixonix: From www.medrxiv.org: Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a sixteen-week interval between doses | medRxiv | 18:14 |
| nixonix | https://pbs.twimg.com/media/E_2l_zaVIAQM0Y-?format=jpg&name=4096x4096 | 18:15 |
| nixonix | prior the first dose of vaccine (V0), three weeks (V1, median [range]: 21 days [13–28 days]) and three months (V2, median [range]: 85 days [73–104 days]) after the first dose of vaccine and three weeks after the second vaccine injection (V3, median [range]: 21 days [13–42 days]) | 18:16 |
| nixonix | notice that naive (who dont have previous infection) vaccinated with 16 weeks interval beat both of those "hybrid immunity" groups (infection + one or 2 doses of vaccine) | 18:20 |
| Brainstorm | New from The Indian Express: World: Joe Biden to double US global donation of COVID-19 vaccine shots → https://is.gd/md78vt | 18:21 |
| nixonix | in circulating neut ab titers at least... | 18:21 |
| nixonix | 3 weeks after the last dose. who knows how is it vs severe, or after several months. but anyways | 18:22 |
| nixonix | .title https://twitter.com/EricTopol/status/1440506163246743562 yeah, but how about those vaxed with longer dose interval? | 18:27 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "5. The variables associated with breakthrough hospitalizations Most notable: Prior covid + vaccine marked protection" | nitter | 18:27 |
| nixonix | imo give it 16 weeks post infection before another dose, if you are pretty sure it was systemic infection. fever and stuff idk | 18:28 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Summary of the evidence to support use of Ivermectin for any covid-related indication pic.twitter.com/z6jW1PzjGx → https://is.gd/x0RcTh | 18:31 |
| Brainstorm | New from StatNews: First Opinion: Opinion: Biden’s global summit Covid-19 targets are woefully inadequate and must be corrected → https://is.gd/0KwgEF | 18:42 |
| nixonix | here's how i would improve these current mrna vaccines (they know all this, and way more, so if they are not doing something like this, there are reasons like production issues, approval and need for new trials, costs etc from the changes - im pretty sure they know what is the most profitable for them to get steady profits from new doses needed): | 18:46 |
| nixonix | both should increase the interval between 1st and 2nd dose. moderna could reduce mrna to something like 50mcg to save it and also titers would reduce lower in shorter time, so 2nd would be more beneficial | 18:47 |
| nixonix | pfizer should optimize its product since 100mcg gives a bit poorer neutralization than 30mcg, peak being perhaps at 50-75 or something. moderna doesnt have similar issue apparently. or pfizer could increase its dose for the 2nd | 18:49 |
| nixonix | both should perhaps use two antigens, like delta spike and one with 484K - SA variant or some recombinant with that mutation. unless it decreases the production too much | 18:50 |
| nixonix | both should test protein adjuvants like unmethylated CpG to induce cxcl13/il-17 for b-cell maturation and lasting protection. mrna for adjuvant production would be added in the vaccine | 18:51 |
| Brainstorm | New from r/WorldNews: worldnews: Chinese whistleblower claims first COVID outbreak was intentional and happened in October 2019 at Military World Games in Wuhan - two months before China notified the world about virus → https://is.gd/bqT2xe | 18:53 |
| nixonix | .title https://wwwnc.cdc.gov/eid/article/27/11/21-1557_article | 19:00 |
| Brainstorm | nixonix: From wwwnc.cdc.gov: Early Release - COVID-19 Vaccination Coverage, Intent, Knowledge, Attitudes, and Beliefs among Essential Workers, United States - Volume 27, Number 11—November 2021 - Emerging Infectious Diseases [...] | 19:00 |
| Brainstorm | Updates for Greenland: +24 cases (now 528), +1963 tests (now 70717) since 22 hours ago | 19:00 |
| Brainstorm | New from Politico: Coronavirus: EU, US announce ‘partnership’ on global vaccine distribution effort → https://is.gd/lFOXn6 | 19:04 |
| nixonix | .title https://twitter.com/bjornpiltz/status/1440655738196557825 | 19:11 |
| Brainstorm | nixonix: From twitter.com: Björn Piltz (@bjornpiltz): "The pressure is up! No wages for unvaccinated in quarantine. https://www.spiegel.de/politik/deutschland/gesundheitsminister-beschliessen-ende-der-lohnfortzahlung-fuer- [...] | 19:11 |
| nixonix | .title https://twitter.com/pbleic/status/1440569286460727301 they used to be rare when pre-alpha and esp delta | 19:18 |
| Brainstorm | nixonix: From twitter.com: Paul Bleicher (@pbleic): "1/With ongoing “spin” that breakthrough infections are “rare” from public health officials and media, the reality - in a 79% vaccinated prison population, the attack rate was [...] | 19:18 |
| nixonix | .title https://www.telegraph.co.uk/news/2021/09/21/wuhan-scientists-planned-releaseskin-penetrating-nanoparticles/ didnt read yet, but lets read together | 19:26 |
| Brainstorm | nixonix: From www.telegraph.co.uk: Wuhan scientists planned to release coronavirus particles into cave bats, leaked papers reveal | 19:26 |
| Brainstorm | New from WebMD: Some States Limit Monoclonal Antibody Treatment to High-Risk, Unvaccinated Patients: At least two states are recommending that doctors prioritize the limited supply of monoclonal antibody treatments for high-risk COVID-19 patients, including unvaccinated people who face severe disease. → https://is.gd/RTFTSS | 19:26 |
| nixonix | "A Covid-19 researcher from the World Health Organisation (WHO), who wished to remain anonymous, said it was alarming that the grant proposal included plans to enhance the more deadly disease of Middle-East Respiratory Syndrome (Mers) | 19:32 |
| nixonix | well maybe it would become endemic flu-like too, like sars2 is supposed to become... | 19:33 |
| Brainstorm | Updates for Italy: +3963 cases (now 4.6 million), +67 deaths (now 130488) since 23 hours ago | 19:37 |
| de-facto | nixonix, where is that quote from? | 19:46 |
| nixonix | that telegraph article. there's discussion in twitter (prob many places, tho), ill link a thread... lots of familiar names, including irene tosetti who invited daszak (: | 19:47 |
| de-facto | i meant the mers statement | 19:48 |
| nixonix | me too | 19:49 |
| nixonix | .title https://twitter.com/R_H_Ebright/status/1440423160042590208 | 19:49 |
| Brainstorm | nixonix: From twitter.com: Richard H. Ebright (@R_H_Ebright): ""Wuhan scientists were planning to release enhanced airborne coronaviruses into Chinese bat populations to inoculate them against diseases that could jump to [...] | 19:49 |
| nixonix | or do you mean original source of it? | 19:49 |
| nixonix | i dont know if telegraph got it straight from him or from that Drastic group, or wherever | 19:50 |
| de-facto | ah yeah there (had to disable their annoying JS paywall) | 19:50 |
| nixonix | noscript is handy | 19:51 |
| nixonix | along with ublock origin | 19:51 |
| de-facto | why would they want to innoculate bats when they know they would not clear the virus from their body? | 19:51 |
| de-facto | afaik their immune system is different from ours | 19:52 |
| nixonix | hundreds of post in the thread. link here if you find something interesting, im not reading all of them | 19:52 |
| nixonix | posts | 19:52 |
| nixonix | yeah i was thinking the same, maybe not true claim or just some suggested idea | 19:52 |
| de-facto | is it about putting some artificial virus into serial passage of a natural reservoir? | 19:54 |
| nixonix | it isnt described that clearly, but from the article it looked liked they had plans or ideas that they could vaccinate bats so that they wouldnt get infected by human coronaviruses, which could then combine in bats' ideal immune system creating recombinant viruses that would infect humans easily and would be already airborne infecting between | 20:00 |
| nixonix | humans (and picked up something nasty when in bats) | 20:00 |
| Brainstorm | Updates for Spain: +130 cases (now 4.9 million), +7 deaths (now 85990) since 22 hours ago | 20:02 |
| nixonix | and the other plans were those chimeric viruses with added pathogenicity like cleavage sites in mers etc | 20:02 |
| nixonix | those spikes generally prevent viruses to get back easily to the same cells where they were produced. but instead have a bit more diffucult time, and more likely to find other cells, that were not infected | 20:03 |
| nixonix | but then if those spikes, especially if they are rigid (like having prolines in them), may have hard time to find receptors they bind efficiently, so further evolution with less flexibility helps the spikes to brush easily on cells surfaces to find the receptors | 20:05 |
| nixonix | and then easy cleavage like furin site, makes many of them more flexible already in ERGIC where they are built | 20:06 |
| nixonix | tmprss2 would cut both those cleavage sites afaik, but doesnt happen too often | 20:07 |
| nixonix | i dont know mers, but maybe it has rigid spikes that are not cleavaged efficiently | 20:07 |
| nixonix | P681R mutation makes furin cleavage even easier (as does P681H if i recall), in the beginning of PRRAR motif | 20:09 |
| nixonix | some claim that PRRAR in ancient variants proves it was not made in purpose, since it isnt optimal. but they dont know necessarily what is optimal, as if you make it too easy, it will go back to the cell where it came from. its a balance game, and the fittest will survive (not saying it was necessarily added on purpose, even if it was a lab leak - | 20:12 |
| nixonix | and if it was on purpose, you test and add pieces from other viruses, not trying to plan an ultimat virus from the beginning) | 20:12 |
| nixonix | why do they have different numbers of S-spikes? average 26 or something like that, but it varies a lot. its by no accident, but evolution towards optimal, so they can infect easily different types of cells, with different sizes and densities of ACE2 and TMPRSS2 | 20:18 |
| lastshell | https://www.npr.org/sections/health-shots/2021/09/22/1039272244/is-the-worst-over-modelers-predict-a-steady-decline-in-covid-cases-through-march | 20:19 |
| nixonix | i wonder if theres a web site dedicated for those forecasts... | 20:22 |
| lastshell | there is one | 20:25 |
| nixonix | graveyard of epidemiologists. with numbers of forecasts that turned out good in tombstones, and number of models that somehow got it right (by a chance) | 20:26 |
| lastshell | https://covid19.healthdata.org/united-states-of-america this one nixonix | 20:26 |
| lastshell | yeah I thing is hard to predict behavior | 20:27 |
| nixonix | i mean past forecasts | 20:28 |
| lastshell | https://www.cdc.gov/coronavirus/2019-ncov/science/forecasting/forecasting-us-previous.html | 20:28 |
| nixonix | i dont want more forecasts... btw, IHME had 35% estimate for prevalence in usa in early may (they increased it at the time, when it used to be less in late april or so, like 30%). at the time cdc's estimate was very close | 20:29 |
| nixonix | but i looked at IHME's recent estimate, and it was even less than a few months ago, for usa (their european estimates were just bad - generally too low imo) | 20:30 |
| nixonix | but i thought maybe they put lots of effort in usa and got it close to right. idk | 20:30 |
| lastshell | the first link has the IMHE logo | 20:30 |
| nixonix | thats why i mentioned it, its IHME | 20:31 |
| nixonix | .tr ihme <fi | 20:31 |
| Brainstorm | nixonix, English to English: ihme <fi (Google) | 20:31 |
| nixonix | damn, how did this work... | 20:32 |
| nixonix | .tr ihme <en | 20:32 |
| Brainstorm | nixonix, English to English: ihme <en (Google) | 20:32 |
| nixonix | .tr ihme <fin | 20:32 |
| Brainstorm | nixonix, English to English: ihme <fin (Google) | 20:32 |
| nixonix | god damn it! screw you guys, im going home | 20:33 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): "will be remembered as one of the best examples of using data in the fight against COVID-19"nature.com/articles/d4158… @NatureNV by @oziadiasAgree 💯 pic.twitter.com/Is8vA8exrH → https://is.gd/oHKmJC | 20:41 |
| de-facto | .tr <fi ihme | 20:42 |
| Brainstorm | de-facto, Finnish to English: Miracle (Wikipedia, Wikipedia) — Miracles (Wikipedia) — wonder (Google) | 20:42 |
| Arsanerit | .tr <fi riisuuntukaa | 20:43 |
| Brainstorm | Arsanerit, Finnish to English: undress (MyMemory) — take off (Google) | 20:43 |
| lastshell | https://boriquagato.substack.com/p/the-vaccinated-superspread-hypothesis | 20:45 |
| nixonix | .title https://www.nature.com/articles/s41591-021-01535-y | 20:47 |
| Brainstorm | nixonix: From www.nature.com: The lesson of ivermectin: meta-analyses based on summary data alone are inherently unreliable | Nature Medicine | 20:47 |
| de-facto | its a bit like a unix pipe %tr <fi <content> | 20:47 |
| de-facto | piping from "fi" to "%tr" | 20:47 |
| de-facto | .tr <auto ihme | 20:49 |
| Brainstorm | de-facto, Pulie-Rauto to English: | 20:49 |
| de-facto | lol | 20:49 |
| nixonix | there was some guy they hired in florida as a surgeon general. i looked for information on him. he was in harvard with eric feigl-ding, but has since been in that hcq scheme | 20:49 |
| nixonix | and guess what else? ivermectin with mccullough and like... | 20:49 |
| nixonix | .title https://twitter.com/MegEileenGreen/status/1440465630444986372 and kory. i wonder who finances these, all that ivm scam, and hcq before it | 20:52 |
| Brainstorm | nixonix, the URL could not be loaded | 20:52 |
| nixonix | .title https://twitter.com/MegEileenGreen/status/1440465630444986372 | 20:52 |
| Brainstorm | nixonix: From twitter.com: MG, MD (@MegEileenGreen): "I was heartbroken when I found out that Dr. Pierre Kory is behind the whole group promoting ivermectin. He was the best critical care doc, and one of the best teachers in my [...] | 20:52 |
| nixonix | .title https://www.sarasotamagazine.com/news-and-profiles/2021/09/joseph-a-ladapo-named-florida-surgeon-general | 20:56 |
| Brainstorm | nixonix: From www.sarasotamagazine.com: Gov. Ron DeSantis Names Dr. Joseph A. Ladapo Florida Surgeon General | Sarasota Magazine | 20:56 |
| nixonix | .title https://www.miamiherald.com/news/coronavirus/article254412224.html | 20:57 |
| Brainstorm | nixonix: From www.miamiherald.com: New FL surgeon general opposes mask, vaccine mandates | Miami Herald | 20:57 |
| nixonix | "When asked whether Florida should be promoting vaccines, Ladapo replied that too much emphasis had been placed on that approach. “The state should be promoting good health, and vaccination isn’t the only path for that,” Ladapo said. “It’s been treated almost like a religion, and that’s just senseless.” | 21:01 |
| nixonix | .title https://www.wsj.com/articles/are-covid-vaccines-riskier-than-advertised-11624381749 by surgeon general Joseph A. Ladapo and Harvey Risch | 21:01 |
| Brainstorm | nixonix: From www.wsj.com: Are Covid Vaccines Riskier Than Advertised? - WSJ | 21:01 |
| nixonix | who is behind all this, who pays them? | 21:02 |
| nixonix | .title https://www.medpagetoday.com/infectiousdisease/covid19/87797 | 21:02 |
| Brainstorm | nixonix: From www.medpagetoday.com: No Evidence That Doctor Group in Viral Video Got Near COVID 'Front Lines' | MedPage Today | 21:02 |
| nixonix | labapo is there too, check if some other familiar names | 21:02 |
| nixonix | ladapo | 21:03 |
| nixonix | .title https://mobile.twitter.com/RandomOpOnions/status/1384796936666972161 | 21:03 |
| Brainstorm | nixonix: From mobile.twitter.com: Random OpOnions (@RandomOpOnions): "Is this the same Joseph Ladapo from the Reagan medical center that has advocated for the use of Ivermectin and hydroxychloroquine last year?" | nitter | 21:03 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2020.09.30.20204693v1 Joseph A. Ladapo, John E. McKinnon, Peter A. McCullough, Harvey A. Risch - no, not worth reading prob (i didnt) | 21:03 |
| Brainstorm | nixonix: From www.medrxiv.org: Randomized Controlled Trials of Early Ambulatory Hydroxychloroquine in the Prevention of COVID-19 Infection, Hospitalization, and Death: Meta-Analysis | medRxiv | 21:03 |
| Brainstorm | Updates for Qatar: +138 cases (now 235907), +5308 tests (now 2.6 million) since a day ago | 21:04 |
| Brainstorm | New from COVID19 Vaccine Tracker: Andy Becker: Altimmune Inc: AdCOVID → https://is.gd/bnKPpU | 21:13 |
| nixonix | .title https://twitter.com/MatBrnstein/status/1440712652867600390 prob more to follow in the thread (there was topol's trolling above this one) | 21:16 |
| Brainstorm | nixonix, the URL could not be loaded | 21:16 |
| Brainstorm | New from COVID19 Vaccine Tracker: Andy Becker: Aivita Biomedical Inc: AV-COVID-19 → https://is.gd/qrWy9m | 21:24 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Further evidence of Moderna edge vs Pfizer in kidney transplant patients and those undergoing dialysismedrxiv.org/content/10.110… with significantly higher mean antibody titer response (Figure) and seroconversion rates (65% vs 35% after 1st dose, respectively) pic.twitter.com/CoJtHFqbE6 → https://is.gd/RhwXLA | 21:45 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): Political polarisation and the tribalism that goes with it can be quite deadly. Here Covid mortality in the US against the % that voted for Trump in 2020. twitter.com/charles_gaba/s… → https://is.gd/kpyPcW | 22:09 |
| TurboTech | Howdie Howdie | 22:10 |
| TurboTech | Cepheids new cartridge for this winter. https://cepheid.widen.net/s/vdxl5wwglx/cepheid-xpert-cov-2-flu-rsv-plus-flyer-eua-0854-english | 22:16 |
| TurboTech | Regarding sars cov it will look for 3 targets instead of two. | 22:16 |
| de-facto | hey TT :) | 22:22 |
| de-facto | no targets on s for lineage discrimination? | 22:22 |
| de-facto | pcr in 25 minutes, thats neat :)) | 22:24 |
| TurboTech | Previous was 55 minutes | 22:24 |
| nixonix | sars1 or 2? what kind of targets? | 22:25 |
| TurboTech | Current sars cov2 is 55 minutes | 22:25 |
| TurboTech | This new cartridge will look to pick up variants as well so there has to be a common gene target in there. | 22:25 |
| TurboTech | Here is all information avail. https://www.cepheid.com/en_US/tests/Critical-Infectious-Diseases/Xpert-Xpress-CoV-2-Flu-RSV-plus#product-resources | 22:26 |
| nixonix | but can you recognize long deletions in N? | 22:26 |
| nixonix | was in open reding frame... | 22:27 |
| nixonix | .title https://www.mdpi.com/1999-4915/13/9/1870/htm | 22:28 |
| Brainstorm | nixonix: From www.mdpi.com: Viruses | Free Full-Text | Multiple Occurrences of a 168-Nucleotide Deletion in SARS-CoV-2 ORF8, Unnoticed by Standard Amplicon Sequencing and Variant Calling Pipelines | HTML | 22:28 |
| de-facto | "Robust design with three distinct gene targets for SARS-CoV-2: N2, E, RdRP" | 22:31 |
| Brainstorm | Updates for Germany: +8053 cases (now 4.2 million) since 23 hours ago | 22:31 |
| nixonix | singapore rocketing, despite one of worlds highest vacc coverage. almost all pfizer and moderna (also some chinavax, so that ccp allows travelling there). why's that? | 22:39 |
| nixonix | i think that it proves my hypothesis, what comes down, must go up again. they are just in that phase now | 22:41 |
| Brainstorm | New from COVID tweets: Trevor Bedford (@trvrb): The @fredhutch is recruiting for a faculty position in Infectious Disease Phylodynamics / Genomic Epidemiology. COVID-19 has pushed pathogen genomics well into the future and now is the time to advance research on methods/applications for sequence data.apply.interfolio.com/92807 pic.twitter.com/h8rPt7OTVu → https://is.gd/Mf8SFU | 22:45 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1440667618457784328 piers morgan was vaxed (and vocal proponent of vaxing), but seems to have some long covey problem. so its not just a flu even when recently vaxed | 22:52 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "I am tired of some academics (some virologists) downplaying the physiological and immunological consequences of Cov2 infection It's rhetorical damage [...] | 22:52 |
| de-facto | TurboTech, what is your opinion about this? https://www.science.org/doi/10.1126/scitranslmed.abc7075 | 22:55 |
| TurboTech | sorry guys I had to take a phone call | 23:05 |
| TurboTech | If lamp works we should use it. I am all for technology. | 23:07 |
| TurboTech | Keep an eye on NY's numbers | 23:08 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Difference between protection, VE for symptomatic infections during extended follow-up of Pfizer and Moderna Pfizer data nejm.org/doi/full/10.10… pic.twitter.com/jTViAJEbuu → https://is.gd/0riGAI | 23:09 |
| TurboTech | Regarding long covid or long term problems. If you have endothelial dysfunction or an immune system that is not at the top of its game, a vaccine will only do so much (probably keep you alive) but I do not think it can help with the exacerbation of the pre existing conditions. | 23:09 |
| nixonix | .title https://twitter.com/EricTopol/status/1440506163246743562 | 23:12 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "5. The variables associated with breakthrough hospitalizations Most notable: Prior covid + vaccine marked protection" | 42l - nitter | 23:12 |
| nixonix | theres some comorbidities and their effect listed. the last one, previous infection as a strong protective factor, it could perhaps be replaced by just longer interval of doses. check my earlier comment and link to support the idea from logs (in topic), earlier today | 23:18 |
| TurboTech | I was watching a few videos and one video broke down an Isreili study that stated that longer term pre covid infection was more effective than Vaccine alone. | 23:19 |
| TurboTech | Wait let me restate that. | 23:20 |
| TurboTech | According to the study. from least effective to most effective. Vaccine alone-Covid infection- Covid infection + Vaccine | 23:21 |
| Brainstorm | New from ProPublica: Chicago Mayor Lori Lightfoot Proposes Further Traffic Ticket Reforms to Help Low-Income Motorists: by Melissa Sanchez ] ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up for Dispatches , a newsletter that spotlights wrongdoing around the country, to receive our stories in your inbox every week. Chicago [... want %more?] → https://is.gd/YDQz6Y | 23:21 |
| TurboTech | I just have a problem believing that a vaccine which is a small part can provide longer immunity that a whole virus. It does not stimulate anywhere near as many processes then the real thing. It can't. Maybe I am missing something. | 23:22 |
| TurboTech | I think New York Deaths are on the verge of exploding. | 23:23 |
| TurboTech | I think we will play a game of Tag your it from South to north | 23:24 |
| nixonix | theres been lots of critique against the study that video prob refers. like here (there's a typo in the first tweet confusing what was meant): | 23:25 |
| nixonix | .title https://twitter.com/PeterHotez/status/1431609669685059591 | 23:25 |
| Brainstorm | nixonix: From twitter.com: Prof Peter Hotez MD PhD (@PeterHotez): "1/5 This @medrxivpreprint has generated some confusion, with some making the case that if you are recovered + infected, then you have the best protection of [...] | 23:25 |
| nixonix | not all the infections give any kind of lasting immune memory. it may be just in upper airways, not systemic infection. those in hospital get a good infection, but the purpose of vaccines is try to avoid infection and the damages | 23:27 |
| nixonix | good *protection | 23:27 |
| TurboTech | I need to find the Isreili study | 23:27 |
| TurboTech | How ever you spell it. | 23:28 |
| TurboTech | It was huge. | 23:28 |
| TurboTech | size wise | 23:28 |
| TurboTech | It was like 20% of the population | 23:28 |
| lastshell | hey guys is true moderna offer better protection than pfizer ? | 23:28 |
| nixonix | those vaccines just arent very good yet for long protection. that israeli study is in that tweet, but its a bad study | 23:28 |
| LjL | another israeli study? they gave us none before, now they're shooting out one per day? | 23:29 |
| nixonix | we have discussed about this, and also moderna vs pfizer etc. pretty much everything, exp what comes out tomorrow... | 23:30 |
| Brainstorm | Updates for Kuwait: +38 cases (now 411316), +1 deaths (now 2442), +15197 tests (now 4.1 million) since 22 hours ago | 23:40 |
| nixonix | .title https://www.cloverbiopharma.com/news/83.html uses a type of CpG adjuvant i wrote earlier about, which prob activates follicular dendritic cells needed for b-cell maturation and better lasting protection | 23:48 |
| Brainstorm | nixonix: From www.cloverbiopharma.com: Clover’s COVID-19 Vaccine Candidate Demonstrates 79% Efficacy Against Delta in Global Phase 2/3 SPECTRA Trial Dominated by Variants of Concern and Interest - Clover Biopharmaceuticals | 23:48 |
| nixonix | .title https://www.cell.com/cell-reports/pdf/S2211-1247(21)01243-2.pdf mclellan in the team, so prob worth a look | 23:52 |
| Brainstorm | nixonix: From www.cell.com: Home: Cell Press | 23:52 |
| nixonix | *Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognitionp, li { white-space: pre-wrap; } | 23:52 |
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