| de-facto | i wonder if such research can lead to the design or artificial antigen to stimulate more robust vaccine induced immunity by lowering the escape probability by antigenic drift of pathogen epitopes | 00:03 |
|---|---|---|
| nixonix | yeah i had a look on that. anyone knows how the patent issues go with these monoclonal antibodies, found from convalescent plasma | 00:08 |
| Brainstorm | Updates for Zimbabwe: +199 cases (now 129333), +2 deaths (now 4602), +10471 tests (now 1.4 million) since a day ago | 00:12 |
| de-facto | its not only about those monoclonals, its about evasive selection, something that will be our enemy as long as COVID is a thing | 00:12 |
| nixonix | "I tried in the 1990s to get a patent for an antibody inhibiting any protease. No one had done it, no one had filed; there were no examples where an antibody could trap a protease in its active state versus an inactive state. It was a big idea, right? The examiner came back and said, “No. Too broad.” And in the end they gave me any antibody | 00:17 |
| nixonix | that would inhibit this particular protease. That was a disappointment | 00:17 |
| nixonix | so maybe all the epitopes of sars2 are already under patent of big pharmas... | 00:18 |
| nixonix | it seems its not that bad, but not good either: | 00:19 |
| nixonix | "But now, reading this Amgen v. Sanofi case, I wouldn’t even get that. They would only give me that particular antibody inhibiting that particular protease, just like PCSK9. That’s all you’re getting: just one particular antibody. So if someone gets another antibody with a different sequence, it’s not protected | 00:19 |
| nixonix | "I find it very disappointing that this is the direction patents are going with antibodies, because it’s slicing the salami so thin that you can’t get a meal off of it. So that’s a disappointment. | 00:26 |
| nixonix | cry me a rive | 00:26 |
| nixonix | r | 00:26 |
| nixonix | some of them have modified Fc ends to improve effector functions like for cytotoxic immune cells. not sure how relevant they are with sars2, though. i think the common view is currently, that not very relevant | 00:29 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1441649886664044544 | 00:33 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "any immunologist worth their salt will understand cov2 will select out those with inborn interferon errors, and select for other traits." | nitter | 00:33 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1441477118341353474 | 00:35 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "many immunologists are too afraid to speak out bc of the censorship and fear bad news brings." | 42l - nitter | 00:35 |
| nixonix | brainström, could you invite leonardi to this thread (or anybody who has twitter acc). id like to hear his take on the expectations of the authors: https://twitter.com/EricTopol/status/1441835361181700101 | 00:42 |
| nixonix | those views of immunologists are so rare and hard to find. i know quite a few immunologists' twitter accounts, but mostly they dont comment too much about immunopathology or future prospects of sars2 | 00:45 |
| Brainstorm | New from Reddit (test): Covid2019: How the current COVID-19 surge is affecting medical care for children in North Idaho: Healthcare workers in Moscow said they are seeing nearly daily COVID-19 outbreaks in daycare and school settings. → https://is.gd/u16G1z | 00:49 |
| nixonix | one way to look for endemic rona (simplifying for things like evolution of both rona and vaxes): vax on average reduces bad outcomes for like 80% (more when its recent, and less when its not - and more for deaths, but possibly less for some permanent damages) | 01:04 |
| nixonix | so its probably around 5 breakthroughs, and youll have similar bad outcomes than unvaxed from 1 infection. something like that | 01:05 |
| nixonix | exp that those are more likely to happen during the weeks when it has waned quite a bit, and you wait for the next dose | 01:06 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Seattle nurse describes burnout and abuse pushing many healthcare workers to their limits: "It's the verbal and physical abuse from visitors and family members that's been some of the most challenging aspects of providing care" → https://is.gd/EGXS0v | 01:10 |
| jbwncster | why can't people just wear a mask while walking in a group right behind me ugh | 01:38 |
| Brainstorm | Updates for Latvia: +816 cases (now 154219), +7 deaths (now 2682), +30587 tests (now 4.3 million) since a day ago — Canada: +21 deaths (now 27652) since 23 hours ago | 01:39 |
| sdfgsdfg | are we going to have another wave :( | 02:20 |
| sdfgsdfg | I hope not | 02:20 |
| Brainstorm | Updates for United Kingdom: +32381 cases (now 7.6 million), +152 deaths (now 136222) since 23 hours ago — Curacao: +36 cases (now 16339), +1 deaths (now 160), +1757 tests (now 272684) since a day ago — Guinea: +5 cases (now 30348), +1 deaths (now 377), +1149 tests (now 552022) since 21 hours ago — Switzerland: +1 cases (now 833384) since a day ago | 02:29 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.06.10.21258647v2.full-text | 02:33 |
| Brainstorm | de-facto: From www.medrxiv.org: Seasonal variation in SARS-CoV-2 transmission in temperate climates | medRxiv | 02:33 |
| de-facto | "We find strong seasonal patterns, consistent with a reduction in the time-variable Rt of 42.1% (95% CI: 24.7% – 53.4%) from the peak of winter to the peak of summer." | 02:36 |
| de-facto | hence to avoid another wave we need to require Rt(winter) ~ 1.421 Rt(summer) < 1 meaning we must have had achieved Rt(summer) < 1.421 with same variant and vaccinations etc | 02:39 |
| nixonix | bossche says there will be HUGE wave in israel | 02:48 |
| nixonix | .title https://twitter.com/KatherineEban/status/1400403612325515266 havent read the article, just saw the twitter thread linked. maybe interesting | 02:49 |
| Brainstorm | nixonix: From twitter.com: Katherine Eban (@KatherineEban): "BREAKING: my months-long @VanityFair investigation on #COVID19 origins is live. Interviews w/ over 40 people, review of hundreds of pgs. of U.S. gov't docs. incl. [...] | 02:49 |
| nixonix | .title https://twitter.com/DavidLWindt/status/1441857279607836677 | 02:50 |
| Brainstorm | nixonix: From twitter.com: David Windt (@DavidLWindt): "13) @GVDBossche: "What I'm expecting in Israel to see is that this movement of waves will come down, will calm down, you will end up with this high plateau, a little bit [...] | 02:50 |
| de-facto | the waves will continue until the pathogen is not tolerated to circulate anymore | 02:51 |
| de-facto | maybe in a few years people will start to realize that | 02:51 |
| nixonix | yeah. while bossche isnt totally wrong about those vaccine evading variants (the previous tweets in the thread), these current variants developed before vaccines, and the same is possible vax or not, and vaccines have and will save lots of life and health | 02:52 |
| nixonix | they just need to be re-dosed frequently enough. both for saving health, and reducing chances for new immune evasion variants. too waned vax is a leaky vax | 02:53 |
| nixonix | and better vaccines will come. its just hard even getting meager 10-20M financing anymore, when the market is stuck from big pharma vaxes, trials are harder and harder to execute, fight for production capacity etc. even great looking novavax which was just a bit late | 02:56 |
| de-facto | vaccines will lower the risk of severe progressions by maybe an order of magnitude, but they wont stop the pandemic, its too late for that | 02:57 |
| de-facto | maybe at the begin with more homogenous genome and much less reproduction number there was such a window of opportunity | 02:58 |
| de-facto | but since we did not even achieve to vaccinate the richest countries, how can we expect to expand that to the whole world? | 02:59 |
| nixonix | it was impossible task to give 90% of worlds population couple of doses within the timescale their protection lasts. and many will refuse anyway | 02:59 |
| de-facto | i would argue that it was not impossible, it was just not nearly tried hard enough | 03:00 |
| de-facto | https://www.statnews.com/2021/09/20/covid-19-set-to-overtake-1918-spanish-flu-as-deadliest-disease-in-american-history/ | 03:02 |
| de-facto | .title | 03:02 |
| Brainstorm | de-facto: From www.statnews.com: Covid overtakes 1918 Spanish flu as deadliest disease in U.S. history | 03:02 |
| nixonix | yeah maybe. just build new plants to produce the most effective vaxes. but some of them dont want western vaxes, china wants to use their own, and whats those depending on their investmens eg in africa, where they havent been too willing to vax anyway, lots of doses expiring when only few wants them | 03:03 |
| nixonix | *wants those | 03:03 |
| de-facto | 1700 fatal outcomes from COVID in USA every day, that is one every 50s | 03:04 |
| nixonix | .title https://twitter.com/DrEricDing/status/1441379567839559682 | 03:05 |
| Brainstorm | nixonix: From twitter.com: Eric Feigl-Ding (@DrEricDing): "8) let’s reframe kids deaths this way - pediatric cancers are the leading cause of death in the US past infancy. #COVID19 deaths in kids is now on par with annual [...] | 03:05 |
| nixonix | while theres no guarantee that novavax would be more lasting (theres a good chance, imo) than these current mrna vaxes, lots of the world use inferior chinese waxes - which are just bad vs delta - when they could use novavax instead right now | 03:08 |
| de-facto | as demand still is not nearly satisfied by supply the vaccine that is offered first is the best | 03:10 |
| nixonix | probably hundreds of vax projects still alive (and hundreds died in lack of financing, most likely), but not many of them will have a chance to even try to go through trials. and those few that will, are prob not the most promising looking, but those that can make a deal with some big pharmas | 03:11 |
| nixonix | india has large pharma industry, but production problems with vaxes. south korea has pretty large too, but where are the vaxes they have planned to produce there | 03:12 |
| nixonix | damn plastic bags, i wonder if novavax has got them now | 03:13 |
| de-facto | there probably is only one way to get rid of the problem: wartime grade effort without compromises | 03:14 |
| nixonix | they have decided that it goes pharma business as usual | 03:14 |
| de-facto | if we want that? obviously until now we decided against that approach, hence for dealing with ongoing waves of COVID | 03:14 |
| de-facto | pharma will not end the virus from spreading, it will only prevent deaths from infections to a certain degree | 03:16 |
| nixonix | im vax once or twice a year, and oral or nasal every couple of months. because not enough doses yet available, and not everybody will take them anyway, it wont disappear, but it wouldnt affect that much anymore, exp those unvaxed | 03:18 |
| nixonix | i dont believe in bossche's vision of completely immune evading variants, or even close. it probably wont evolve to some airborne hiv | 03:20 |
| nixonix | "chinese flying aids", as they used to say | 03:20 |
| de-facto | ultimately it means that humanity is not fit for globalization as we proved to be unable to deal with a relatively simple pathogen | 03:20 |
| de-facto | maybe that means the great filter is still in front of us and we are just another insignificant species vanishing in the fermi paradox | 03:22 |
| de-facto | i would have wished for a much much stricter zero-covid approach worldwide, we could have learned so much from that | 03:23 |
| nixonix | yeah, i think there should be more border control for viruses. these what were last winter, prevented flu to spread much. some day they will check it easily from breath. sure first they will miss those who are in early phase, but anyways | 03:24 |
| trbp | de-facto: not having globalization would not hinder research? | 03:25 |
| nixonix | fermi paradox, i think the its nuclear weapons, that makes every technological culture that could communicate on radio waves very short living | 03:25 |
| de-facto | oh i am not saying we could avoid globalization, i am saying we should use the opportunity to learn from COVID how to deal with biosecurity in a globalized world to prevent a more deadly pathogen from creating the next pandemic | 03:26 |
| trbp | de-facto: pandemics will come and go, such as far human mankind did survive, even with less medical knowledge | 03:27 |
| de-facto | humanity never was as globalized as it is right now | 03:28 |
| nixonix | vaccine production capacity is the key. we had these mrna vaxes in a few days after chinese sent the sequence | 03:28 |
| trbp | and besides 0 covid approach would had also end in less scientific material for nice suiting statistics, would it have not? | 03:28 |
| de-facto | this is a first time situation that a pathogen can spread over the whole globe in days | 03:29 |
| nixonix | luckily this virus wasnt that hard to develop somewhat working vaccines, unlike some others | 03:29 |
| de-facto | trbp, well zero-covid strategy would have required to exactly evaluate and cut the transmission path of this respiratory virus (hence equip us with both, knowledge and ability to do that to any other such pathogen) | 03:30 |
| nixonix | but while its said that mutation rate of sars2 is only half of flu, which is half of hiv, its not actually true anymore. it picked up speed year ago | 03:31 |
| nixonix | .title https://twitter.com/DrEricDing/status/1441379567839559682 | 03:31 |
| Brainstorm | nixonix: From twitter.com: Eric Feigl-Ding (@DrEricDing): "8) let’s reframe kids deaths this way - pediatric cancers are the leading cause of death in the US past infancy. #COVID19 deaths in kids is now on par with annual [...] | 03:31 |
| de-facto | sure we learn a lot about viral evolution with ongoing waves of new variants of COVID | 03:31 |
| de-facto | but not so much about how to contain those by ending transmission paths in the most efficient way if that is not the declared goal of the approach | 03:32 |
| de-facto | i bet most people that got COVID cant exactly tell where they got infected | 03:32 |
| de-facto | hence, that would be the first starting point to develop methods to find that out | 03:33 |
| de-facto | and obviously traveling via plane still spreads the variants in days to weeks all over the world | 03:34 |
| nixonix | are there some countries anymore who want to contain it? i think everybody want to let it rip when they reach some vaccine coverage (among adults or over 12 yo) | 03:34 |
| de-facto | that is the next thing, we have the nagging suspicion its the travelers for two years by now and we still dont even have an idea how to prevent that | 03:35 |
| de-facto | i always was (and i always will be) for strictest zero-covid approach without compromises | 03:36 |
| de-facto | but oh well, that is nothing but wishful thinking | 03:36 |
| nixonix | our hc officials didnt even try to stop delta. they removed the travel restrictions in the beginning of june. 15 days and cases went up again | 03:36 |
| de-facto | yeah 2021 pretty much was a repetition of 2020 | 03:37 |
| trbp | does that strictful contain the fastest 0 infection as fast approachable as possible | 03:37 |
| trbp | so full lockdown again, for lets say 6 weeks and who still lives lives rest has 0 infection after put neatly in their body bags? | 03:38 |
| nixonix | .title https://www.telegraph.co.uk/news/2020/07/01/thousands-czechs-hold-farewell-party-pandemic-prague-country/ we should have parties like this again | 03:38 |
| Brainstorm | nixonix: From www.telegraph.co.uk: Thousands of Czechs hold 'farewell party' for pandemic in Prague as country registers spike in cases | 03:38 |
| de-facto | at first it would contain aquiring the knowledge to understand the transmission dynamics in a way that allows for the most efficient approach to cut transmission paths | 03:38 |
| trbp | de-facto: while you do this all you are still facing the rising numbers of infection... | 03:39 |
| Brainstorm | New from r/Coronavirus: Coronavirus: New Zealand PM Jacinda Ardern Considers No Jab, No Entry Policy → https://is.gd/MGQBfw | 03:39 |
| nixonix | whens nz going to let it rip? | 03:40 |
| de-facto | i did not say lockdown, i said ending the infection chains (on purpose generic enough to include all possible approaches emerging from a more targeted understanding towards transmission dynamics) | 03:40 |
| trbp | de-facto: infection chain is broken most effectively by? | 03:41 |
| trbp | is using mask >> lockdown? | 03:41 |
| trbp | or lockdown >> using mask? | 03:41 |
| de-facto | just as one example: if we would ramp up testing strategy *massively* and give everyone a test at least twice a week we would possibly be able to isolate enough infected that the pathogen would strictly stay at Rt<<1 | 03:41 |
| trbp | de-facto: we could also end up in some shady companies and people ending up seeing business in it | 03:42 |
| de-facto | we would learn where it hides and build up an infrastructure that easily also could cover other pathogens | 03:42 |
| trbp | and financial ministers who get nightmares about how to put that into the households of their national budget | 03:43 |
| trbp | de-facto: so pathogens are clever? they play hide and seek? | 03:43 |
| de-facto | technically that is trivial, e.g. PCR already covers primers for other pathogens that can be tested in parallel, with same sample | 03:43 |
| trbp | sure but how much does a pcr cost? | 03:43 |
| de-facto | lol nope, pathogens are not clever, but we are too dump to find their transmission paths because they simply use every opportunity they got to do one thing: reproduce | 03:44 |
| trbp | and are all worldwide equipped and trained enough to make that dream possible? | 03:44 |
| nixonix | here its over 100e, but can be way more depending on logistics etc in smaller townds (evern 500, i just read) | 03:44 |
| nixonix | the cost for health institutes | 03:45 |
| de-facto | if its ramped up enough a PCR test costs much much less than what is charged for it today | 03:45 |
| trbp | or do we again need hordes of hardware and trained personel for it? | 03:45 |
| de-facto | no that would not scale | 03:45 |
| de-facto | it must be done on a decentralized way not depending on human workers | 03:45 |
| nixonix | my solution for keeping cases low is tight borders, then trace the cases down, using regional bar closures and what is needed to get them down | 03:45 |
| nixonix | keep it down untill kids have been vaxed | 03:46 |
| trbp | is the waste of a mask more neglectable than the waste of plastic tracers used for all that pcr? | 03:46 |
| de-facto | it should be based only on machines (that can be produced in an efficient way), should work without human intervention and must consume as few consumables as possible (to avoid the supply and waste problems) | 03:46 |
| trbp | what is worse for worlds pollutioning? | 03:46 |
| nixonix | while that takes a few months, its only good, because more information from other countries experiences, long covid, permanent brain and organ damages - and even 2nd gen vaccines during that time | 03:46 |
| de-facto | i am pretty sure that technically that is possible, probably even trivial | 03:46 |
| nixonix | then if everything looks good enough, let it rip maybe... | 03:47 |
| trbp | de-facto: this efficent way of production is best done in vegan workshops and not globalized world economics i guess ;) | 03:47 |
| nixonix | im pretty sure some asian countries plan to do that | 03:47 |
| de-facto | i am serious, you are not, alright. | 03:47 |
| nixonix | but maybe nobody in europe. nz perhaps, lets see | 03:47 |
| trbp | de-facto: i am dead serious | 03:47 |
| trbp | things not always as easy as seems | 03:48 |
| de-facto | vegan workshops and not globalized economics, lol come on. | 03:48 |
| trbp | ok that one was exaggerated | 03:49 |
| trbp | maybe a bit too much | 03:49 |
| trbp | but you got the hint | 03:49 |
| trbp | that is why you directly diverted to accuse me of beeing not argumentative and gone personal as blaming me for beeing not serious | 03:49 |
| de-facto | i did not say anything against global economy, in fact its nessecary. also the technological problems pretty much are solved i would assume, its only about scaling it in a compatible way | 03:50 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.09.22.21263977v1?rss=1 reminder for turbo | 03:50 |
| Brainstorm | nixonix: From www.medrxiv.org: COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta- [...] | 03:50 |
| de-facto | thats the same value that TurboTech said | 03:51 |
| nixonix | while the claim in the title is pretty wild - was mg/ml the lower or higher number? i remember the ratio was 2.4999 | 03:52 |
| nixonix | ng/ml | 03:53 |
| nixonix | thats the lower. so that equals around 125 using the other unit. i think at equatorial they usually have around 120-200 | 03:55 |
| Brainstorm | New from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): Conspiracy theory?Its a fact that sars/mers covs were being alteredIts a fact that insertion of FCSs was viewed as a "viable" and sufficiently "novel" (among virologists) "scientific" pursuitAs far as I understand, WIV is guarding KFC's secret recipe twitter.com/BioTurboNick/s… → https://is.gd/pzzYfN | 04:01 |
| Brainstorm | Updates for United Kingdom: +31312 cases (now 7.6 million), +138 deaths (now 136253) since 23 hours ago — South Korea: +2770 cases (now 301172), +9 deaths (now 2450), +40598 tests (now 14.3 million) since 22 hours ago — Canada: +2294 cases (now 1.6 million), +23 deaths (now 27659) since 23 hours ago — New Zealand: +5 cases (now 4074), +13442 tests (now 3.3 million) since 2 hours ago | 04:33 |
| Brainstorm | New from r/Science: science: Phase 3 trial results: mRNA-1273 vaccine continued to be safe and efficacious more than five months after second dose → https://is.gd/gROVEY | 05:17 |
| Brainstorm | New from This Week In Virology: TWiV 809: Vampire vax: TWiV reveals isolation from bats in Laos of a SARS-CoV-2 like virus with a spike protein that allows entry into human cells, and exploration of a herpesvirus vector for immunization of vampire bats against rabies virus. → https://is.gd/S9DvLX | 06:10 |
| Brainstorm | Updates for Peru: +887 cases (now 2.2 million), +46 deaths (now 199228), +40352 tests (now 17.7 million) since a day ago | 06:38 |
| Brainstorm | New from r/WorldNews: worldnews: France to double COVID-19 vaccine doses for poorer countries: Macron → https://is.gd/0jNaF7 | 06:52 |
| Brainstorm | New from The Indian Express: World: Macron says France will double covid-19 shots it sends to poor nations – AFP → https://is.gd/Bm0ttb | 07:03 |
| Brainstorm | Updates for Nebraska, United States: +40551 cases (now 301631), +23 deaths (now 2405) since 3 days ago — Selangor, Malaysia: +2341 cases (now 670594) since a day ago — Terengganu, Malaysia: +760 cases (now 52304) since a day ago — Negeri Sembilan, Malaysia: +194 cases (now 96580) since a day ago | 07:40 |
| ZdrytchX | !cases australia | 08:04 |
| ZdrytchX | !help | 08:04 |
| ZdrytchX | .cases | 08:06 |
| Brainstorm | ZdrytchX: Sorry, not found. Either there aren't cases, or it's under a different name. | 08:06 |
| ZdrytchX | .cases australia | 08:06 |
| Brainstorm | ZdrytchX: Australia has had 96972 confirmed cases (0.4% of all people) and 1231 deaths (1.3% of cases) as of 2 hours ago. 37.0 million tests were done (0.3% positive). 15.9 million were vaccinated (62.0%). +1220 cases since 22 hours ago. See https://offloop.net/covid19/?default=Australia | 08:06 |
| Brainstorm | ZdrytchX: If you know of an official or otherwise good site for data about Australia, with a reasonably short URL, please %tell LjL about it. | 08:06 |
| ZdrytchX | wtf 1220? man shits going down in eastern australia | 08:06 |
| Brainstorm | Updates for India: +28326 cases (now 33.7 million), +173 deaths (now 446745), +1581862 tests (now 563.2 million) since 23 hours ago — New Caledonia: +226 cases (now 6185), +11 deaths (now 83) since 23 hours ago | 08:30 |
| Brainstorm | New from The Indian Express (Health): Fashion: Dolce & Gabbana light up Milan fashion week with glittery show → https://is.gd/9MWFb4 | 09:10 |
| Brainstorm | Updates for Czechia: +411 cases (now 1.7 million), +1 deaths (now 30453), +54371 tests (now 37.9 million) since 23 hours ago — Grenada: +63 cases (now 4829), +11 deaths (now 116) since a day ago | 09:32 |
| Brainstorm | New from r/WorldNews: worldnews: Covid-19 origins: Why the search for the source is vital → https://is.gd/b4f4Lo | 09:53 |
| Brainstorm | New from r/Science: science: New study finds patients who received flu vaccine 40% less likely to be hospitalized after contracting COVID. Researchers examined the development of 15 serious coronavirus symptoms within 30, 60, and 120 days from the time patients were diagnosed. → https://is.gd/sTyvmz | 10:24 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 26SEP21 → https://is.gd/RsFmsn | 10:35 |
| Brainstorm | New from The Indian Express (Health): Life-style: The restaurant host is suddenly at the front of the COVID wars → https://is.gd/GunHK1 | 10:45 |
| specing | flu vaccine protects against covid? Interesting | 11:02 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): And obviously myocarditis isn't the only possible outcome of a Covid infection. In Belgium, we estimated that during the 1st wave, ca. 1 in 500 under 24 year olds had to be hospitalised following a SARS-CoV2 infection (that includes asymptomatic & undiagnosed cases). pic.twitter.com/ikk6iIP9PM → https://is.gd/qa3uYR | 11:06 |
| Brainstorm | Updates for Russia: +22498 cases (now 7.4 million), +805 deaths (now 203900), +500000 tests (now 189.8 million) since 23 hours ago — Germany: +6213 cases (now 4.2 million) since 18 hours ago | 11:36 |
| Brainstorm | New from r/WorldNews: worldnews: Putin ends self-isolation with Siberian fishing trip → https://is.gd/YsqKpf | 11:48 |
| Brainstorm | Updates for Poland: +643 cases (now 2.9 million), +1 deaths (now 75572), +71371 tests (now 20.7 million) since a day ago | 12:01 |
| Brainstorm | New from r/WorldNews: worldnews: Why have COVID-19 cases in Tokyo plummeted? Study points to restraint by the unvaccinated. → https://is.gd/kkmvFe | 12:20 |
| Brainstorm | New from COVID tweets: David Boulware, MD MPH (@boulware_dr): One advantage of mRNA vaccines would be the ability to rapidly tweak the mRNA to the latest variant. This hasn't occurred. Why not? What's the FDA regulatory path? And where is the impetus to make this happen? twitter.com/EricTopol/stat… → https://is.gd/Vizqrf | 12:30 |
| Brainstorm | New from The Indian Express: World: Court sets hearing for Wednesday on New York City schools vaccine mandate → https://is.gd/Hp4Itn | 12:41 |
| Brainstorm | New from COVID tweets: Tom Wenseleers (@TWenseleers): En met vaccinatiegraad in de VS die sterk politieke breuklijnen volgt (hier ook met correctie voor leeftijd). pic.twitter.com/WDwyv2XMtG → https://is.gd/K8PXT9 | 12:52 |
| Brainstorm | Updates for Romania: +6333 cases (now 1.2 million), +111 deaths (now 36341), +44270 tests (now 12.6 million) since 23 hours ago — Nepal: +730 cases (now 791392), +9 deaths (now 11096), +8589 tests (now 4.2 million) since 22 hours ago — UAE: +298 cases (now 734894), +1 deaths (now 2090), +338923 tests (now 82.8 million) since 22 hours ago [... want %more?] | 13:41 |
| Brainstorm | Updates for Laos: +292 cases (now 21819), +4816 tests (now 481801) since 13 hours ago — Brunei: +580 cases (now 6540), +5508 tests (now 335986) since 23 hours ago — Faroe Is.: +7 cases (now 1122), +1000 tests (now 427000) since 23 hours ago | 14:06 |
| Brainstorm | Updates for Zambia: +28 cases (now 208857), +1 deaths (now 3646), +3516 tests (now 2.4 million) since 16 hours ago — Denmark: +1 deaths (now 2642), +44980 tests (now 83.4 million) since 12 hours ago | 15:08 |
| Brainstorm | Updates for Bangladesh: +54 cases (now 1.6 million), +22221 tests (now 9.6 million) since 20 hours ago | 15:33 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Brazil hits 70% of total population vaccinated with at least one dose. → https://is.gd/ZCkGel | 15:33 |
| Brainstorm | Updates for Qatar: +67 cases (now 236298), +1 deaths (now 605), +5128 tests (now 2.6 million) since 23 hours ago | 16:10 |
| Brainstorm | New from The Indian Express (Health): Fashion: Gucci launches Vault vintage site during Milan Fashion Week → https://is.gd/DCBGx7 | 16:39 |
| Brainstorm | Updates for Chile: +765 cases (now 1.7 million), +8 deaths (now 37440), +74774 tests (now 21.6 million) since 23 hours ago | 17:00 |
| Brainstorm | New from Reddit (test): Sunday 26 September 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/sxTdRu | 17:22 |
| Brainstorm | Updates for Bangladesh: +980 cases (now 1.6 million), +21 deaths (now 27414) since 23 hours ago | 17:37 |
| Brainstorm | New from Reddit (test): nCoV: Philippines confirms over 20k new COVID-19 cases, no deaths due to technical glitch | 26SEP21 → https://is.gd/Wuj08f | 17:54 |
| Brainstorm | Updates for United Kingdom: +20320 cases (now 7.7 million), +64 deaths (now 136286) since 15 hours ago | 18:02 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Breakthrough infections and hospitalizations in over 3 million fully vaccinated persons @VeteransHealth, mostly pre-Delta wavemedrxiv.org/content/10.110…J&J vaccine less protection vs hospitalization than mRNA vaccines; Moderna more protective than Pfizer pic.twitter.com/tGpVqOaEGQ → https://is.gd/N7RuD1 | 18:04 |
| Brainstorm | New from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): If given the funding to do so (a white elephant) would you insert FCSs into novel coronaviruses? → https://is.gd/maT8Zh | 18:15 |
| Brainstorm | New from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): The question is important. Why?Has the opinion of the suitability of this kind of work changed after this pandemic? Why or why not? → https://is.gd/Vs8jfx | 18:26 |
| Brainstorm | Updates for Greenland: +12 cases (now 565), +1159 tests (now 73745) since 2 days ago | 18:39 |
| Brainstorm | New from Reddit (test): China_Flu: Unvaccinated are also refusing lifesaving antibody treatment - initial reports → https://is.gd/0UviQK | 19:19 |
| Brainstorm | Updates for Italy: +3099 cases (now 4.7 million), +44 deaths (now 130697) since 23 hours ago | 19:29 |
| -Bridgestorm- ⭕ Lindol! Earthquake! 6.1 Mww tremor, registered by 4 agencies, with 14 reports, 14 early, occurred 20 minutes ago (17:12:07 UTC), with a gibbous moon, Talisay, Philippines (13.93, 120.54), ↓50 km likely felt 210 km away (in San Pascual, Bauan, San Pedro, Santa Rosa, Biñan…) by 20.8 million people (quakesearch.geonet.org.nz) | 19:32 | |
| Brainstorm | Updates for Greece: +1100 cases (now 645969), +24 deaths (now 14679), +154045 tests (now 19.3 million) since a day ago — Jordan: +987 cases (now 819783), +11 deaths (now 10680), +26390 tests (now 10.0 million) since a day ago | 20:31 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Some Tri-Cities parents organizing rogue Homecoming dances to avoid COVID precautions: Dozens of Kamiakin High School parents are outraged over new rules for school dances, including showing a negative COVID test or proof of vaccination. → https://is.gd/4keZhS | 20:46 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): South Korea's Delta outbreak. With a population of 51.3 million, limited to avg 7 deaths/day (Total population vaccination: 74% 1st dose, 45% 2-doses)Population-adjusted for US, fatalities would equal 45.Actual number of US deaths/day, 7-day avg = 2,045@OurWorldInData pic.twitter.com/ys8axBft8Z → https://is.gd/6wjdMl | 21:40 |
| nixonix | .title http://www.koreaherald.com/view.php?ud=20210915001070 | 22:10 |
| Brainstorm | nixonix: From www.koreaherald.com: Is Korea bending rules in vaccine sprint? | 22:10 |
| nixonix | "But then again, I don’t think there is data on how the six-week spacing may affect antibody response or adverse event reactions.” | 22:10 |
| nixonix | well there is some data... but i guess hc officials make decisions without finding out | 22:11 |
| nixonix | saw a tweet mentioning this, so i had to check if true (yup): "a survey of bats in southern Mexico reported 8 novel alphacoronaviruses and 4 novel betacoronaviruses, 1 with 96% similarity to MERS-CoV | 22:15 |
| nixonix | "in Saudi Arabia. Although the prevalence of CoVs was high (≈28% of fecal samples), MERS CoV was found in only 1 bat. A 3.5% MERS CoV infection rate (n = 29; 95% CI 0–20%) in T. perforatus bats is low compared with that for severe acute respiratory syndrome–like CoV in rhinolophid bats in China (10%–12.5%) but consistent with CoV prevalence | 22:17 |
| nixonix | among bats in Mexico | 22:17 |
| nixonix | i wonder if they have sars2 nowdays. saudi, mexican or south-east asian bats. or camels | 22:19 |
| nixonix | you ever wondered if llamas could catch mers? | 22:22 |
| nixonix | of course that has been contemplated before. and a thing like that must be tried too... | 22:23 |
| nixonix | "Here we report MERS-CoV transmission from experimentally infected llamas to naïve animals. Directly inoculated llamas shed virus for at least 6 days and could infect all in-contact naïve animals 4-5 days after exposure. | 22:24 |
| nixonix | you can try all kinds of crazy shit, and see what happens... | 22:24 |
| nixonix | .title https://twitter.com/wolfgang_xl/status/1441168093707866119 | 22:45 |
| Brainstorm | nixonix, the URL could not be loaded | 22:45 |
| nixonix | .title https://twitter.com/wolfgang_xl/status/1441168093707866119 | 22:45 |
| Brainstorm | nixonix: From twitter.com: Wolfgang (@wolfgang_xl): "Crazy that the leaked EcoHealth DARPA application isn't getting more news coverage. A novel bat coronavirus with a pangolin spike and a human furin cleavage site is exactly [...] | 22:45 |
| Brainstorm | New from Reddit (test): nCoV: Jakarta Predicts Third Wave of COVID-19 to Hit in December 2021 | 27SEP21 → https://is.gd/u6obe8 | 22:45 |
| nixonix | .title https://old.reddit.com/r/COVID19/comments/pvpvpa/covid19_mortality_risk_correlates_inversely_with/ some discussion on that latest vit d study | 23:04 |
| Brainstorm | nixonix: From old.reddit.com: COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta- [...] | 23:04 |
| nixonix | "50 ng/ml is actually kind of challenging to maintain consistently. I’ve supplemented 5000 IU D3 daily for years and I’m not sure I’ve ever cracked 50 in my annual checks. I’m usually in the 40s. 10,000 IU per day is probably the best dose to maximize D3 levels | 23:04 |
| LjL | is that TurboTech? :P | 23:05 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis ( https://www.zotero.org/groups/covid_links/items/5HW938VN ) | 23:12 | |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis ( https://www.zotero.org/groups/covid_links/items/P8IV7888 ) | 23:12 | |
| nixonix | "Hypercalcemia, defined as a serum calcium level above 2.75 mmol/liter (11 mg/dl), was observed at the highest dose of 95 μg (3,800 IU)/day, which is, therefore, the lowest-observed-adverse-effect level (LOAEL) | 23:14 |
| nixonix | but was it a small, low-fat person, and a rare case? i guess i have to find out more some day | 23:15 |
| nixonix | k2 was mentioned. k2 mk-7 is supposedly the type thats efficient against possible hypercalcemia (i used to eat it, but ive been out for awhile) | 23:16 |
| nixonix | .title https://edition.cnn.com/2021/09/24/asia/turkmenistan-covid-free-nations-intl-hnk-dst/index.html | 23:21 |
| Brainstorm | nixonix: From edition.cnn.com: Turkmenistan claims it hasn't had a single Covid-19 case. Activists say that's a lie - CNN | 23:21 |
| dd_ | calling turkmen liarss, yikes! | 23:43 |
| nixonix | .title https://twitter.com/boulware_dr/status/1442069202165276673 | 23:57 |
| Brainstorm | nixonix: From twitter.com: David Boulware, MD MPH (@boulware_dr): "One advantage of mRNA vaccines would be the ability to rapidly tweak the mRNA to the latest variant. This hasn't occurred. Why not? What's the FDA regulatory [...] | 23:57 |
Generated by irclog2html.py 2.17.0 by Marius Gedminas - find it at https://mg.pov.lt/irclog2html/!