libera/##covid-19/ Friday, 2021-11-12

BrainstormNew from r/WorldNews: worldnews: Covid: Austrians heading towards lockdown for unvaccinated → https://old.reddit.com/r/worldnews/comments/qrx9lw/covid_austrians_heading_towards_lockdown_for/00:07
BrainstormUpdates for Colombia: +2644 cases (now 5.0 million), +40 deaths (now 127680), +51331 tests (now 27.3 million) since a day ago — Argentina: +1460 cases (now 5.3 million), +25 deaths (now 116209), +45769 tests (now 25.5 million) since a day ago00:08
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): People with Prior Covid "have pronounced deficiencies in functional Spike-specific T cell responses and the ability to neutralize [with antibodies] the current variants of concern"medrxiv.org/content/10.110…There's false assurance on "natural immunity" protection; [... want %more?] → https://twitter.com/EricTopol/status/145893496280826265800:18
elephpant[m]<de-facto> "e.g. why not use several..." <- this a major part of the plot of spiderman ps4. Basically AI + crispr. Ingame it back fired vaguely similar to 'I am legend'00:30
BrainstormUpdates for Gibraltar: +72 cases (now 6328), +1312 tests (now 396040) since 23 hours ago — Ghana: +41 cases (now 130649), +3 deaths (now 1206), +7098 tests (now 1.9 million) since a day ago00:32
LjL-Matrix%title https://www.taiwannews.com.tw/en/news/434086200:37
BrainstormLjL-Matrix: From www.taiwannews.com.tw: Taiwan halts 2nd-dose BioNTech vaccinations for ages 12-17 amid concerns of myocarditis | Taiwan News | 2021-11-10 15:42:0000:37
de-factoelephpant[m], interesting i have not seen/played spiderman00:38
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Germany has outperformed the US throughout the pandemic. It also has ~10% more of its total population fully vaccinated, and 💉💉more recently.Today Germany had a pandemic record of new cases, nearly 50,000, and highest deaths (220) since May.Not a good look for [... want %more?] → https://twitter.com/EricTopol/status/145894023467921820300:39
de-factobasically what i meant is redundancy targeting the same function/molecule but on different binding sites00:39
de-factoyeah Germany is having one all-time record after the other in incidence and no peak in sight, i told you so several weeks ago00:40
de-factohmm LjL-Matrix a single dose of BNT probably would not be enough, but i wonder if increasing the delay to second dose would lower the attack rate for myocarditis in boys00:44
rpifangermany sucks pretty much00:50
rpifanthey have mishandled this shit from the start00:50
rpifanand forcing us to all do 2G rules isnt gonna help00:51
rpifanwe need to lockdwon again00:51
rpifanwe are all forced to wear ffp2 masks and yet the cases are higher then ever before, clearly they dont know jack shit anymore00:51
de-factowe need to have more tests not less00:52
de-factowe need to reopen vaccination centers00:52
qkall[m]i just got my booster and flu shot... the person giving the shot was weirded out we were getting both.01:13
qkall[m]i didn't see anything bad about it...01:13
qkall[m]so... we'll seee how it goes 😀01:13
de-factoin different arms?01:13
de-factooh but arent some manufacturers combining them anyhow?01:14
de-factoyeah Moderna for example01:15
qkall[m]yes differnet arms01:32
qkall[m]and i thougth i would get a mixed one like01:32
qkall[m]i got pfizer01:32
qkall[m]so expected moderna01:32
qkall[m]but no01:33
qkall[m]was alittle confused on that01:34
qkall[m]i mean not upset or anythign ubt i just thought htat was the plan01:34
qkall[m]and i can't type ☹️01:34
BrainstormUpdates for Germany: +17400 cases (now 4.9 million), +223 deaths (now 97822) since 19 hours ago — Uruguay: +159 cases (now 395964), +4 deaths (now 6097), +10078 tests (now 3.9 million) since 23 hours ago — Zimbabwe: +27 cases (now 133329), +5288 tests (now 1.5 million) since 23 hours ago01:35
de-factoyeah i mean it would make sense to combine those for a future "winter shot", a vaccine that contains the antigens of several viruses that may cause problems in the winter, such as several CoVs, RSV, Influenza etc01:38
de-factonot quite sure, i think in general having non-replicating vaccine (e.g. not a replicating attenuated "live" vaccine) makes combining the shots much easier as the amount of antigen presented to the immune system then can be balances more easily to ensure a sufficient immune response to any of the contained antigens01:41
de-facto*balanced01:42
* de-facto cant type, despite having a new keyboard lol01:42
lastshelltired of covid01:48
de-factoyeah yet its far from over01:49
lastshellis over is endemic, no way to stop this01:49
de-factoseems AY.4.2 just arrived in north carolina?01:50
de-factoso US import of the newest mutants seems to work quite efficiently01:50
de-factohttps://covid19.sanger.ac.uk/lineages/raw?show=B.1.617.2%2CAY.4.2%2CB.1.177%2CB%2CB.1.351%2CB.1.1.7%2CA&lineage=AY.4.2&scale=quadratic01:52
lastshellI thing the only way to deal with covid at this time is to boost your inmunesystem and just get covid01:53
de-factowell what about reinfections then?01:55
lastshellI don;t know the numbers of reinfections from non-vaccinated01:56
lastshellI know that vaccinated we need to get boosters just to be sure01:56
de-factoyeah i guess immunity becomes better with every shot, but we will see01:57
de-factowith better i mean broader, higher level, potentially longer lasting01:58
lastshellI had a historian teacher01:58
lastshelland he ask one question, the history is lineal, it repeat itself or is just  random ? (something like that was like 20 year ago)01:59
lastshellI been thinking in the spanish flu, that is currently the commmon cold ?01:59
lastshellthe nature of each organism/virus/bacteria whatever02:00
lastshellis to trive02:00
lastshellso virus needs to be less lethal02:00
lastshellto evolve right ?02:00
lastshelllike by nature make sense ?02:01
BrainstormNew from COVID tweets: Double Individual Speculator (@x2IndSpeculator): Spike & non-Spike-specific T cells were detected in >50% of convalescents... Despite the high prevalence... in convalescents at 12 months, T cell functionality, measured by cytokine expression after stimulation with Spike epitopes [... want %more?] → https://twitter.com/x2IndSpeculator/status/145895908290843443402:02
de-factothe "spanish flu" is a particular lethal strain of Influenza virus, currently circulating strains are not nearly as lethal as it was back then02:03
de-factosome scientists recovered the sequence of the genome for the spanish flu, so its possible to reconstruct it (they did that its called "de-novo"), but its foolish, its exceptionally deadly02:04
de-factothe "common cold" is causes by many viruses, not really influenza even, its more a mix of some Adenviruses, Rhinoviruses, RSV, Parainfluenza etc02:05
de-factowith the "less lethal" meme we need to take a more differentiated view: what does it mean for the pathogen *reproduction* if a new mutation is more lethal than its ancestors?02:07
de-factoso to speak the "value" of that mutation is measured in how much it reproduces in comparison to the pathogen without that particular mutation present02:08
de-factoso if we are talking about reproduction of information (mutation) we would need to look at the impact of it on infection chains, hence when in the disease progression the most likely moment of infecting the next susceptible host would be (in order to propagate that mutation further)02:10
BrainstormNew from Virology.ws: Pills for COVID-19: Multiple vaccines have been developed that have made substantial contributions to controlling the COVID-19 pandemic, but where are the antivirals? Only repurposed drugs have been used and not with much success. That situation seems about to change with the authorization of [... want %more?] → https://www.virology.ws/2021/11/11/pills-for-covid-19/02:13
de-factoif that most common moment of transmission to the next host appears to be prior to symptoms occurring (let alone severe progression or fatal outcome), what disadvantage on reproduction would it mean for a mutation if it caused later more severe progression (after it already jumped to the nest host)?02:14
de-factosuch a disadvantage only could occur if the increased mortality would propagate back in time, e.g. if some mutation was so deadly that much more strict containment measures would be implemented in a population and therefore would mean a disadvantage for such a mutant in terms of reproducing its information in the next host02:15
lastshellthat is true02:16
de-factoyet if that is not the case, or only the case to a limited degree (a bit more containment, but still leaky enough to not make it extinct) such a mutation very well could also be more lethal due to increased pathogen fitness on cellular level02:16
lastshellbut at the same time, the inmune system of the humans also needs to evolve02:17
lastshellis kind of like a race of evolution02:18
lastshellI recall sars1 persons had some protection from sars2 ?02:18
de-factoe.g. Delta just being more fit on a cellular level (better adapted to its host), hence it is both, more contagious (due to increased viral shedding of infected and lower initial containment dose kickstarting infection in susceptibles), but also expose carriers to more quantity of antigen hence induce a more severe reaction and progression (thereby be more lethal)02:19
de-factoyes indeed its a race condition02:19
de-factoyes afaik there was even efforts to produce a pan-coronavirus vaccine with combining antigen of both, SARS-CoV-1 and SARS-CoV-202:21
de-factoor at least betacoronavirus vaccine02:22
de-facto.title https://www.nejm.org/doi/full/10.1056/NEJMoa210845302:23
Brainstormde-facto: From www.nejm.org: Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors | NEJM02:23
BrainstormUpdates for Barbados: +300 cases (now 21311), +2 deaths (now 189), +1910 tests (now 409127) since a day ago — United Kingdom: +43398 cases (now 9.5 million) since 23 hours ago02:31
BrainstormNew from r/WorldNews: worldnews: Mandate to get Covid-19 vaccination not a breach of Bill of Rights, New Zealand High Court judge rules → https://old.reddit.com/r/worldnews/comments/qs0k4e/mandate_to_get_covid19_vaccination_not_a_breach/03:05
BrainstormUpdates for Anguilla: +32 cases (now 1109), +1 deaths (now 3) since a day ago03:08
de-facto.title https://www.virology.ws/2021/11/11/pills-for-covid-19/03:12
Brainstormde-facto: From www.virology.ws: Pills for COVID-1903:12
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Oh, cases are "nonsensical"Even though cases beget cases, beget #LongCovid, were the primary endpoint of efficacy for all vaccination trials, and have tracked with hospitalizations and deaths for every wave and recovery phase of the US pandemic twitter.com/mtracey/status… → https://twitter.com/EricTopol/status/145898056922464666003:16
* elephpant[m] uploaded an image: (21KiB) < https://libera.ems.host/_matrix/media/r0/download/converser.eu/VGBAGwUQOUZogeGMpjkBpXmt/Ivermectin.png >03:17
LjL-MatrixMy sister got her booster shot here in Italy and the vaccination center made a pretty poor show this time... they were asking people who were coming in with medical certificates of, like, "immune conditions", and being asked what condition exactly they had, *while in the queue in front of everybody else*. Unlike the other times, there was no private session with a doctor.03:32
LjL-MatrixIsn't this sort of stuff supposed to be pretty private? The privacy authority stops entities from exchanging things sometimes when it would be useful to... and then... this03:33
LjL-MatrixJust reading "The Singaporean government announced this week it will stop covering medical bills for people who are "unvaccinated by choice" after Dec. 8."03:35
BrainstormNew from r/WorldNews: worldnews: World gets tough on the unvaccinated → https://old.reddit.com/r/worldnews/comments/qs111p/world_gets_tough_on_the_unvaccinated/03:37
BrainstormUpdates for New Zealand: +199 cases (now 8307), +57286 tests (now 4.4 million) since a day ago — Australia: +1391 cases (now 187041), +343115 tests (now 45.2 million) since 23 hours ago — Netherlands: +16348 cases (now 2.3 million) since 23 hours ago03:39
BrainstormNew from NPR: 10 states sue Biden administration over COVID vaccine mandate for health care workers: The state attorneys general argue the vaccine mandate will lead to shortages of health care workers and could threaten the [... want %more?] → https://www.npr.org/sections/coronavirus-live-updates/2021/11/11/1054959986/states-lawsuit-biden-administration-covid-vaccine-mandate-health-workers03:47
applePieneo-confederates04:15
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Why are we lucky?—💉became available faster than any in history by many years—Despite 2 years of considerable🦠evolution, our vaccines have maintained remarkably high efficacy w/ a 3rd shot—>90% efficacy >> 50%, preset criteria for FDA approval —Safety [... want %more?] → https://twitter.com/EricTopol/status/145900314915539763504:50
BrainstormNew from r/WorldNews: worldnews: Biden, Xi to address Asia-Pacific leaders on trade, COVID recovery → https://old.reddit.com/r/worldnews/comments/qs2j55/biden_xi_to_address_asiapacific_leaders_on_trade/05:01
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): "It’s our low rate of vaccination — we haven’t done what was necessary ...We are still below 70 percent, I don’t know how we can win this race against time with the fourth wave. I fear we’ve already lost.”nytimes.com/2021/11/11/wor… @kbennhold → https://twitter.com/EricTopol/status/145900814051550412805:11
BrainstormUpdates for Germany: +48834 cases (now 5.0 million) since 23 hours ago05:31
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): For months the media & many experts insisted the vaccines were fully protective vs severe disease while the evidence was pointing against that assertion. Still today @nytimes! No wonder the public is confused and  booster uptake is low. Only 32% in the highest risk age [... want %more?] → https://twitter.com/EricTopol/status/145901799643370291305:42
BrainstormUpdates for India: +12516 cases (now 34.4 million), +501 deaths (now 462690) since 23 hours ago — Peru: +1237 cases (now 2.2 million), +22 deaths (now 200554), +47838 tests (now 19.5 million) since a day ago06:02
BrainstormNew from r/WorldNews: worldnews: German far-right AfD co-leader Alice Weidel contracts COVID → https://old.reddit.com/r/worldnews/comments/qs3vg0/german_farright_afd_coleader_alice_weidel/06:24
BrainstormUpdates for Cayman Islands, United Kingdom: +751 cases (now 3427) since 5 days ago — Negeri Sembilan, Malaysia: +275 cases (now 104910) since a day ago — W.P. Putrajaya, Malaysia: +84 cases (now 7444) since a day ago — Liaoning, China: +52 cases (now 606) since a day ago06:39
BrainstormNew from The Indian Express: World: Covid-19 hotspots offer sign of what could be ahead for US → https://indianexpress.com/article/world/covid-19-hotspots-united-states-florida-7619303/07:38
BrainstormNew from r/WorldNews: worldnews: Taiwan suspends 2nd doses of Pfizer for teens over health risk → https://old.reddit.com/r/worldnews/comments/qs5c40/taiwan_suspends_2nd_doses_of_pfizer_for_teens/07:58
BrainstormUpdates for Germany: +48835 cases (now 5.0 million) since 21 hours ago08:44
BrainstormNew from r/Coronavirus: Daily Discussion Thread | November 12, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/qs6h7h/daily_discussion_thread_november_12_2021/09:01
BrainstormUpdates for Czechia: +10414 cases (now 1.9 million), +66 deaths (now 31355), +101818 tests (now 41.7 million) since a day ago — Georgia: +4445 cases (now 775826), +77 deaths (now 10816), +50782 tests (now 10.8 million) since a day ago09:09
Guest17anyone here09:09
Guest17China's Sichuan Province 's government just made a ridiculous news:)09:10
Guest17they said that their Chinese medicine 's protective efficacy of Chinese medicine is similar to that of the BNT162 vaccine09:12
Guest17http://www.xichang.gov.cn/szfxx_15907/202111/t20211112_2075142.html09:12
Guest17“根据我省对2.2万例社区居民中药预防对照研究显示:中药对整体人群的保护率为91.8%,对16-60岁人群保护率尤为明显,达到95%。”09:12
Guest17u can translate that into english by deepl by urself09:14
BrainstormNew from EMA: What's new: General: Procedural advice for veterinary vaccine antigen master file (VAMF) certification → https://www.ema.europa.eu/en/procedural-advice-veterinary-vaccine-antigen-master-file-vamf-certification09:43
BrainstormUpdates for Hungary: +8370 cases (now 939784), +116 deaths (now 31867), +37324 tests (now 7.8 million) since a day ago — Lithuania: +2683 cases (now 439373), +20 deaths (now 6271), +24041 tests (now 5.8 million) since a day ago10:05
BrainstormUpdates for Armenia: +1309 cases (now 326830), +70 deaths (now 6937), +11431 tests (now 2.2 million) since a day ago — Taiwan: +10 cases (now 16475), +27448 tests (now 7.9 million) since a day ago10:29
BrainstormNew from Reddit (test): CoronavirusUK: Netherlands to impose partial lockdown to halt COVID-19 surge - media → https://old.reddit.com/r/CoronavirusUK/comments/qs760m/netherlands_to_impose_partial_lockdown_to_halt/10:47
BrainstormNew from StatNews: Opinion: Broadband access: Health care’s newest challenge: American lawmakers and policymakers have an opportunity to learn from the Covid-19 crisis and ensure that every American has access to quality care in the digital age, and that includes… → https://www.statnews.com/2021/11/12/broadband-access-newest-challenge-health-care/10:57
BrainstormUpdates for Laos: +2143 cases (now 52175), +3 deaths (now 94), +6729 tests (now 707778) since 14 hours ago11:07
BrainstormNew from r/WorldNews: worldnews: UK Covid rates are now falling rapidly despite dire warnings for the winter → https://old.reddit.com/r/worldnews/comments/qs80f4/uk_covid_rates_are_now_falling_rapidly_despite/11:19
BrainstormNew from COVID tweets: Dr Raghib Ali MD(Epi) MPH MSc(Epi) MA DLSHTM FRCP (@drraghibali): Important paper on deaths in children & young people (CYP) in 1st year of pandemic. Reassuring results for Covid: - of 12 million CYP in England, 3105 died - of these, 25 (<1%) were due to Covid - 99.995% of CYP with [... want %more?] → https://twitter.com/drraghibali/status/145910241826066432311:30
BrainstormUpdates for Poland: +12965 cases (now 3.2 million), +31 deaths (now 78555), +387192 tests (now 22.9 million) since 23 hours ago — Austria: +11798 cases (now 934948), +40 deaths (now 11641), +445216 tests (now 102.6 million) since a day ago — Slovakia: +6843 cases (now 547052), +41 deaths (now 13446), +23203 tests (now 4.2 million) since a day ago [... want %more?]11:32
BrainstormNew from BMJ: Encouraging covid vaccine uptake and safe behaviours—an uphill struggle against government complacency: Like many doctors who had stepped back from clinical practice, I volunteered to return to the NHS to help deal with the covid-19 pandemic. After much bureaucracy, my contribution has been as a... → http://www.bmj.com/content/375/bmj.n2773.short12:01
BrainstormUpdates for Belarus: +1939 cases (now 623628), +15 deaths (now 4820), +351951 vaccines (now 3.1 million), +31700 tests (now 10.0 million) since 21 hours ago — Indonesia: +399 cases (now 4.3 million), +20 deaths (now 143628), +812079 vaccines (now 128.1 million), +259817 tests (now 49.6 million) since 23 hours ago12:09
BrainstormNew from r/WorldNews: worldnews: France : According to the most recent government report, Covid related hospitalizations represented 2% of the total number of hospitalizations in France in 2020. → https://old.reddit.com/r/worldnews/comments/qs8rvk/france_according_to_the_most_recent_government/12:22
BrainstormNew from ECDC: Data on COVID-19 vaccination in the EU/EEA: The downloadable data files contain information on COVID-19 vaccination in the EU/EEA. The data are presented in the Vaccine Tracker and collected through The European Surveillance System (TESSy). → https://www.ecdc.europa.eu/en/publications-data/data-covid-19-vaccination-eu-eea12:33
BrainstormNew from BBC Health: AstraZeneca to take profits from Covid vaccine: The drugs giant signs new deals, but poorer countries will continue to get the vaccine at cost price. → https://www.bbc.co.uk/news/business-5925622313:26
BrainstormUpdates for Vietnam: +8982 cases (now 1.0 million), +81 deaths (now 22930), +292234 tests (now 63.7 million) since 23 hours ago — Latvia: +1388 cases (now 238153), +37 deaths (now 3683), +16707 tests (now 5.2 million) since 23 hours ago — Iceland: +181 cases (now 15321), +7627 tests (now 1.2 million) since 23 hours ago [... want %more?]13:36
BrainstormUpdates for Croatia: +6449 cases (now 528286), +53 deaths (now 9774), +15067 tests (now 3.2 million) since 23 hours ago — Romania: +4844 cases (now 1.7 million), +307 deaths (now 52513), +48406 tests (now 15.4 million) since a day ago — Estonia: +945 cases (now 210542), +12 deaths (now 1662), +6841 tests (now 2.2 million) since a day ago [... want %more?]14:01
de-facto.title https://twitter.com/covSpectrum/status/145761911276767641614:06
Brainstormde-facto: From twitter.com: CoV-Spectrum (@covSpectrum): "CoV-Spectrum can now also be used with fully #opendata! The sequence data is from @NCBI GenBank and pre-processed by @nextstrain. You can switch the data source with a click on the arrow below the logo or use the link https://open.cov-spectrum.ethz.ch/ In the open build, you can 1/" | nitter14:06
de-facto.title https://open.cov-spectrum.ethz.ch14:06
Brainstormde-facto: From open.cov-spectrum.ethz.ch: covSPECTRUM14:06
de-facto.title https://github.com/cevo-public/cov-spectrum-website14:07
Brainstormde-facto: From github.com: GitHub - cevo-public/cov-spectrum-website: A web platform to detect and analyze variants of SARS-CoV-214:07
de-factofantastic tool for tracking mutations trajectories per country14:07
BrainstormNew from BBC Health: Covid: Dutch set for partial lockdown as infections surge: The measures are expected to last three weeks, while Austria plans a lockdown for the unvaccinated. → https://www.bbc.co.uk/news/world-europe-5925840914:08
aradeshoffloop site still seems broke :/14:16
BrainstormNew from BMJ: Covid-19: Hospitals move to create extra bed capacity to relieve pressure: NHS hospitals across the UK are creating extra bed capacity to relieve ongoing operational pressures from covid-19 and to tackle the growing backlog in elective care.Reports are increasing of trusts... → http://www.bmj.com/content/375/bmj.n2775.short14:18
de-factoanother one14:25
de-facto.title https://sarscoverage.org/index.html14:25
Brainstormde-facto: From sarscoverage.org: CoVerage: SARS-CoV-2 lineage dynamics - Home14:25
de-facto"This webresource shows the epidemiological dynamics of SARS-CoV-2 lineages in individual countries/regions based on viral genome sequence data shared via GISAID. It identifies those that rise significantly in frequency over time. "14:26
BrainstormNew from r/Science: science: Data show COVID-19 vaccines do not cause infertility, but getting coronavirus can. Pregnant women who get COVID-19 are more likely to deliver their babies prematurely and may be admitted to the intensive care unit or die at a higher rate than uninfected women. → https://old.reddit.com/r/science/comments/qsatok/data_show_covid19_vaccines_do_not_cause/14:29
BrainstormUpdates for Switzerland: +3922 cases (now 909034) since 23 hours ago — Germany: +48879 cases (now 5.0 million) since 22 hours ago14:44
de-facto.title https://www.youtube.com/watch?v=iNVnvAwMjbU&t=47s14:47
Brainstormde-facto: From www.youtube.com: Aktuelle Corona-Lage mit Jens Spahn (CDU) & Lothar Wieler (RKI) | Komplette BPK 12. November 2021 - YouTube14:47
de-factoPress conference today about COVID disaster in Germany14:48
de-factoaudio in German language, auto-generated subtitles offer auto-translate feature in other languages14:49
BrainstormNew from COVID19 Vaccine Tracker: Andy Becker: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/14:50
de-factoreopening of vaccination centers14:56
de-factoreturn to free test for citizens14:58
lastshellUS states have cases increase in 22 states14:59
lastshellextrange highly vaccinated states also are getting cases increased15:00
BrainstormNew from COVID19 Vaccine Tracker: Andy Becker: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/15:01
de-factotransition from 3g to 2g+, meaning public events only for vaccinated and recovered WITH test15:01
de-factofinally15:01
de-factoexample: yesterday we had 50k infections in Germany, approximately 3k will need hospitalization, 350 will end up in ICU and at least 200 will not survive COVID15:05
de-factoall for a SINGLE day of infections in Germany15:06
BrainstormNew from COVID19 Vaccine Tracker: Andy Becker: AnGes: AG0302-COVID19 → https://covid19.trackvaccines.org/vaccines/31/15:11
BrainstormUpdates for Iran: +7322 cases (now 6.0 million), +109 deaths (now 127918), +550946 tests (now 36.8 million) since a day ago — Denmark: +844 cases (now 417151), +336356 tests (now 88.2 million) since 22 hours ago — Bangladesh: +221 cases (now 1.6 million), +5 deaths (now 27912), +17231 tests (now 10.6 million) since 19 hours ago [... want %more?]15:16
BrainstormNew from COVID19 Vaccine Tracker: Andy Becker: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/15:22
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Regkirona, regdanvimab, COVID-19 virus infection, Date of authorisation: 12/11/2021, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/regkirona15:33
BrainstormNew from EMA: What's new: News: COVID-19: EMA recommends authorisation of two monoclonal antibody medicines → https://www.ema.europa.eu/en/news/covid-19-ema-recommends-authorisation-two-monoclonal-antibody-medicines15:54
BrainstormNew from r/WorldNews: worldnews: Austria is preparing a COVID-19 lockdown for unvaccinated people only → https://old.reddit.com/r/worldnews/comments/qscqs9/austria_is_preparing_a_covid19_lockdown_for/16:05
BrainstormNew from r/WorldNews: worldnews: Latvia bans unvaccinated lawmakers from voting, docks pay → https://old.reddit.com/r/worldnews/comments/qscvki/latvia_bans_unvaccinated_lawmakers_from_voting/16:15
BrainstormUpdates for Chile: +2940 cases (now 1.7 million), +19 deaths (now 37936), +82901 tests (now 24.3 million) since 23 hours ago — Canada: +1464 cases (now 1.8 million), +17 deaths (now 29322) since 23 hours ago — Greenland: +8 cases (now 990), +1292 tests (now 95490) since 23 hours ago16:36
BrainstormNew from BMJ Open: Current trends in the application of causal inference methods to pooled longitudinal non-randomised data: a protocol for a methodological systematic review: Introduction Causal methods have been adopted and adapted across health disciplines, particularly for the analysis of single studies. However, [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/11/11/e05296916:48
lastshelldamn 1 in 48 people in the state is infected (Colorado)16:57
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): What is the principal reason for Europe's surge?Insufficient vaccination/immunityWhy does this portend trouble for the US?Our vaccination rate is 58.5%, considerably less than countries that are surging in the EU, and our counter to waning with 3rd shots is moving [... want %more?] → https://twitter.com/EricTopol/status/145918774444222873716:58
de-facto.title https://www.nature.com/articles/s41586-021-04186-817:24
Brainstormde-facto: From www.nature.com: Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 | Nature17:24
BrainstormNew from r/WorldNews: worldnews: Austria plans to approve lockdown for the unvaccinated on Sunday → https://old.reddit.com/r/worldnews/comments/qsemoz/austria_plans_to_approve_lockdown_for_the/17:30
BrainstormUpdates for Netherlands: +16227 cases (now 2.3 million), +33 deaths (now 19138) since 18 hours ago — Greece: +6832 cases (now 821900), +56 deaths (now 16616), +502356 tests (now 29.7 million) since a day ago17:32
de-facto.title https://www.nature.com/articles/d41586-021-02795-x17:38
Brainstormde-facto: From www.nature.com: COVID super-immunity: one of the pandemic’s great puzzles17:38
de-facto.title https://corona-datenspende.de/science/en/reports/prolongedchanges/17:45
Brainstormde-facto: From corona-datenspende.de: Changes in vital data after a COVID-19 infection · Science Blog17:45
LjL-MatrixMedical visit today... Auras may be good but god does it get horribly hot and humid inside17:58
LjL-MatrixEspecially since I'm already anxious17:58
de-factoi wear my 3M Aura 9330++ the whole day at work, one of the most convenient and best fitting masks i have had so far18:06
de-factoi even did wear it when driving home with bicycle, its *more* comfortable in the cold air outdoors18:08
de-factoyet in general its a bad idea to wear them outdoors since when its cold the exhaled air will very quickly condensate in the mask filters18:08
de-factoand wet filters later on will be not effective anymore, they only work properly when they are dry18:09
de-factohence i did that only when driving home where i could hang the mask to dry for the next day18:09
de-factoi highly recommend the 3M Aura 9330 series, those are awesome, and now even affordable, around 5€ per mask18:10
LjL-MatrixI'm not outdoors18:11
LjL-MatrixI'm not sure I'd call 5 per mask "affordable" :p I can afford it because I don't wear it every day18:11
LjL-MatrixAnyway I don't know how you can wear this all days, seems utter hell to me18:11
LjL-MatrixAll day*18:11
de-factowell i do wear it many days in a row (yes i know not recommended, yet i do it anyway)18:12
LjL-MatrixI hope I'm waiting in the right place...18:12
Raf[m]N95 respirators are very restrictive on breathing and temperature regulation18:12
Raf[m]Is that an N95?18:12
de-factoprobably should get many masks and rotate them, e.g. one mask for Mondays, another for Tuesdays etc so they could hang dry for a week18:12
LjL-MatrixRaf: it's an FFP2 because Europe but essentially yes18:12
Raf[m]de-facto: That's not a bad idea18:13
de-factoRaf[m], not sure, i guess FFP3 is N99 or N100 in US standards18:13
LjL-MatrixAnd unlike the *cheap* FFP2s this one actually has good fit so it feels like hell18:13
Raf[m]Personally I'm not as concerned about getting exposed so I use a surgical mask18:13
LjL-MatrixThe cheap ones just let air in from not-the-mask...18:13
Raf[m]That's right18:13
de-factoyes the Auras really have airtight fit, very well designed and thought through18:13
Raf[m]If you truly want protection you really need a good fit and an N95 or better18:14
LjL-MatrixRaf: well I'm in a clinic waiting in a small corridor for a doctor in a tiny room who has other people in it right now18:14
LjL-Matrixde-facto: I still think the straps are terrible and I always hurt my face putting it on :p18:14
de-factoyeah the rubber straps are the weak point of them18:15
LjL-MatrixThe very first mask I bought at the start of the pandemic had the best straps18:15
LjL-MatrixSliding through holes18:15
LjL-MatrixUgh I'm 15 min late now and I'm not fully sure I'm waiting in the right place18:15
de-factoactually i thought about buying fabric straps in the tailors store or how those are called and replace the rubber bands with those18:15
de-factowhich one do you have LjL-Matrix ?18:16
de-facto9320 or 9330?18:16
de-factoblue or red straps?18:16
LjL-Matrix9320, blue18:18
LjL-MatrixIt's the P218:18
de-factoits the one that was winning the testing competition on Stiftung Warentest18:20
de-factohttps://www.test.de/Masken-Welcher-Mund-Nasen-Schutz-hilft-am-besten-gegen-Corona-5692592-0/18:22
LjL-MatrixI think I'm about to win the Fainting Competition18:24
de-factoi guess 3M is the expert in designing good filters, e.g. combining good fit with good filter performance (low air resistance yet filtering out the majority of tiny particles)18:26
de-factoi also like their design, they naturally follow the movements of the face when talking to other people while maintaining an airtight fit18:29
de-factodue to their different folding patterns in contrast to the "normal" N95 ones18:29
LjL-MatrixThis place is barely aerated18:31
de-factoluck you that you got your trusty 9320 with you then18:32
BrainstormUpdates for Luxembourg: +179 cases (now 84248), +1 deaths (now 855), +3143 tests (now 3.6 million) since a day ago — Switzerland: +4 cases (now 909038) since 3 hours ago18:35
de-factoactually thinking about the rubber bands: they may make not the best impression BUT since they are rubber they would stay on the position where they are placed (e.g. on the hairs etc)18:37
de-factoin contrast to textile straps, which may move over the hairs with time, hence thereby (when going around the head) end up hurting the ears after a while (when they moved down the curvature of the head over the hairs)18:39
de-factoso maybe rubber material really is one of the best choices there18:39
BrainstormNew from Medical Xpress: Study finds coronavirus lurks and lingers in nursing home patients' rooms: Even though most COVID-19 cases come from exposure to airborne coronavirus, a new study points to the importance of surfaces as a reservoir of risk in nursing homes—especially certain [... want %more?] → https://medicalxpress.com/news/2021-11-coronavirus-lurks-lingers-nursing-home.html18:45
BrainstormNew from COVID tweets: Chloe Reichel (@chloereichel): We need on-ramps for COVID mitigation measures, @profbardlaw writes in her latest for @PetrieFlom.  blog.petrieflom.law.harvard.edu/2021/11/12/the… → https://twitter.com/chloereichel/status/145921682185753805518:57
BrainstormUpdates for Spain: +4353 cases (now 5.0 million), +26 deaths (now 87673) since 20 hours ago — Jordan: +2393 cases (now 888435), +14 deaths (now 11197), +83924 tests (now 11.4 million) since 21 hours ago18:59
BrainstormNew from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): The safety of public spaces needs to be addressedVested interests are afraid of a new status quo of ventilation/ filtrationThey will oppose recognition of needed infrastructure or engineering updatesCovid isn't going away, and it won't [... want %more?] → https://twitter.com/fitterhappierAJ/status/145921852111269479519:07
BrainstormUpdates for United Kingdom: +39203 cases (now 9.5 million), +149 deaths (now 143116) since 23 hours ago — Canada: +1398 cases (now 1.8 million), +15 deaths (now 29324) since 21 hours ago19:37
BrainstormNew from r/WorldNews: worldnews: Hong Kong reports third Covid-19 case involving ‘Delta Plus’ variant → https://old.reddit.com/r/worldnews/comments/qsh9a4/hong_kong_reports_third_covid19_case_involving/19:39
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Colorado and California broadening eligibility for boosters (3rd shots) for all adults. 6 months after mRNA, 2 months after J&JGood. That's what the data supports to fully restore vaccine effectiveness to >90% pic.twitter.com/l4Yct1r3lw → https://twitter.com/EricTopol/status/145923098184863334619:49
BrainstormUpdates for Italy: +8522 cases (now 4.8 million), +68 deaths (now 132686), +498935 tests (now 109.8 million) since a day ago20:02
BrainstormNew from NPR: Europe and Russia battle a new wave of COVID-19: More lockdowns are in the offing, as Germany and Austria shatter daily case counts and Russia has become become the world leader in new COVID-19 deaths. → https://www.npr.org/sections/coronavirus-live-updates/2021/11/12/1055100209/europe-russia-covid-cases-surge-spike20:10
BrainstormUpdates for Central African Rep.: +87 cases (now 11666), +1 deaths (now 101) since 11 days ago — France: +126 cases (now 7.4 million) since 23 hours ago20:39
BrainstormNew from WebMD: Long COVID: More Clues Coming, but No 'Aha' Moments Yet: For many survivors of COVID-19, problems, sometimes severe, linger. Medicine is racing to catch up with the elusive diagnosis and treatment. → https://www.webmd.com/lung/news/20211112/long-covid-clues-coming20:41
de-facto.title https://depositonce.tu-berlin.de/handle/11303/1386220:43
Brainstormde-facto: From depositonce.tu-berlin.de: DepositOnce: Nachhaltige Strategien gegen die COVID-19-Pandemie in Deutschland im Winter 2021/202220:43
de-facto"Sustainable strategies against the COVID-19 pandemic in Germany in winter 2021/2022 " in German language20:43
aradeshcovid deniers are driving me nuts guys21:01
aradeshthey live in la-la land21:01
aradeshi can't resist arguing with them21:03
aradeshand then it's this horrible banging head against the wall process21:03
aradeshwhere you're arguing against someone living in an alternate reality21:04
aradeshevery thing they return is built on another false assumption built on another false assumption, and so on21:05
aradeshand if you dig down eventually you get to, "you aren't naive to believe what they tell you are you?"21:05
TurboTechDefine Denier?21:06
TurboTechHas anyone in this room gotten Covid 19?21:07
aradeshTurboTech: basically people who think it's fake and gay, or "just the flu", or that the hospitals being overwhelmed is a myth, or that the vaccines are untested and dangerous21:11
aradeshand so on21:11
aradeshwhole variety of ideas that float around in their circles21:11
aradeshTurboTech: most likely21:12
BrainstormNew from COVID tweets: Paul Sax (@PaulSaxMD): With vaccine effectiveness waning, case numbers rising, and no concerning safety signals from boosters so far, is it time to recommend a booster for all adults? Here I argue yes. Plus, simplifies @CDCgov guidance.Latest: blogs.jwatch.org/hiv-id-observa… @drlucymcbride @EricTopol → https://twitter.com/PaulSaxMD/status/145924926274353971421:13
TurboTechWell It is very real.21:14
TurboTechI have significant problems with other parts of Healthcare.21:15
BrainstormNew from CIDRAP: News Scan for Nov 12, 2021: COVID, flu vaccines given at same time Polio in Africa → https://www.cidrap.umn.edu/news-perspective/2021/11/news-scan-nov-12-202121:24
BrainstormUpdates for Dominican Rep.: +1160 cases (now 393383), +7 deaths (now 4165), +11129 tests (now 2.3 million) since a day ago21:29
BrainstormNew from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: November 12, 2021 → http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-november-12-202121:34
TurboTech.title https://www.mdpi.com/2072-6643/13/11/4047/htm21:40
BrainstormTurboTech: From www.mdpi.com: Nutrients | Free Full-Text | Rapid and Effective Vitamin D Supplementation May Present Better Clinical Outcomes in COVID-19 (SARS-CoV-2) Patients by Altering Serum INOS1, IL1B, IFNg, Cathelicidin-LL37, and ICAM1 | HTML21:40
BrainstormNew from COVID tweets: Prof Francois Balloux (@BallouxFrancois): Was this reckless, or does it imply that the baseline risk of pathogen pandemic-causing spillovers into humans is low. This raises a set of interesting questions. BTW, European wildlife is as riddled with pathogens as African or Asian ones, [... want %more?] → https://twitter.com/BallouxFrancois/status/145926191279814246821:56
BrainstormUpdates for Maldives: +165 cases (now 89529), +3133 tests (now 1.6 million) since a day ago — Kuwait: +24 cases (now 412960), +17342 tests (now 5.0 million) since a day ago22:31
BrainstormNew from COVID tweets: Marc Veldhoen (@Marc_Veld): Puerto-Ricos, an other example that removing politics out of vaccines works. statnews.com/2021/11/03/man… → https://twitter.com/Marc_Veld/status/145927334263310336322:38
de-factoi have a liquid vitamin D3 supplement where 1 drop contains 5000 I.U. so they recommend one *drop* per 5 days, hence a tiny bottle a year worth of supply22:41
de-factoi guess it should be more like 1 drop each 1-2 days or such?22:41
de-facto.title https://www.medrxiv.org/content/10.1101/2021.11.12.21266222v122:54
Brainstormde-facto: From www.medrxiv.org: Age and product dependent vaccine effectiveness against SARS-CoV-2 infection and hospitalisation among adults in Norway: a national cohort study, January to September 2021. | medRxiv22:54
de-facto" Using Cox proportional hazard models on data from 4 293 544 individuals (99% of Norwegian adults), we estimated overall, age-, and product-specific vaccine effectiveness against SARS-CoV-2 infection, hospitalisation, ICU admission and death in Norway, using data from national registries."22:57
de-facto"accine status was included as time-dependent variable and we adjusted for sex, pre-existing medical conditions, country of birth, county of residence, and crowded living conditions."22:57
de-facto"Adjusted vaccine effectiveness among fully vaccinated is 72.1% (71.2-73.0) against SARS-CoV-2 infection, 92.9% (91.2-94.2) against hospitalisation, 95.5% (92.6-97.2) against ICU admission, and 88.0% (82.5-91.8) against death. Among partially vaccinated, the effectiveness is 24.3% (22.3-26-2) against infection and 82.7% (77.7-86.6) against hospitalisation."22:57
de-facto"Vaccine effectiveness against infection is 84.7% (83.1-86.1) for heterologous mRNA vaccine regimens, 78.3% (76.8-79.7) for Spikevax (Moderna; mRNA-1273), 69.7% (68.6-70.8) for Comirnaty (Pfizer/BioNTech; BNT162b2), and 60.7% (57.5-63.6) for Vaxzevria (AstraZeneca; ChAdOx nCoV-19; AZD1222) with a mRNA dose among fully vaccinated."22:57
BrainstormNew from CIDRAP: Non-White race tied to higher risk for COVID infection, severity: Mary Van Beusekom | News Writer | CIDRAP News Nov 12, 2021 Black, Hispanic, and Asian people are at higher risk for infection and an ICU stay, a large study finds. → https://www.cidrap.umn.edu/news-perspective/2021/11/non-white-race-tied-higher-risk-covid-infection-severity22:59
BrainstormUpdates for Bahrain: +19 cases (now 277184), +15342 tests (now 7.1 million) since a day ago23:08
BrainstormNew from Reddit (test): CoronaVirus_ITALIA: Un numero «insolitamente elevato» di Calciatori stanno crollando in Campo per problemi Cardiaci. Lecito chiedersi se cio' possa essere imputato ai Vaccini? La lista del quotidiano tedesco → https://old.reddit.com/r/CoronaVirus_ITALIA/comments/qsm0pk/un_numero_insolitamente_elevato_di_calciatori/23:10
de-factoHonestly i do think if we do not go into a strict lockdown in Germany soon, we are heading into disaster with overwhelming the healthcare system23:17
BrainstormUpdates for Mali: +42 cases (now 16605), +2 deaths (now 584), +1216 tests (now 468000) since 3 hours ago23:39
BrainstormNew from COVID tweets: Derek Lowe (@Dereklowe): Extremely unpleased to see the way that Covid cases are increasing again here in MA. Now I regret complaining about how slowly they were going down! → https://twitter.com/Dereklowe/status/145928899792301670723:42
bolovanos__de-facto, what is meant by "heterologous mRNA vaccine regimens"?23:51
de-factoare there more than two mRNA vaccines approved in Norway?23:54

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