| LjL | dTal, but for the avoidance of doubt, it feels like spraying water, not like spraying algae :P | 00:00 |
|---|---|---|
| dTal | No I'm pretty sure it's indeed pretty bio-inert | 00:00 |
| dTal | mostly it just seems like a pain in the ass | 00:00 |
| LjL | i don't know, many people routinely spray all sorts of nasal sprays, multiple times a day, because they have sinusitis or other common issues | 00:00 |
| dTal | it's true that I don't have statistics on P3 respirators *handy* | 00:01 |
| LjL | i spray it before leaving home and when i come back, takes all of ten seconds - if i remember | 00:01 |
| ndn[m] | what if the carageenan causes your chindrip! | 00:01 |
| ndn[m] | extra moisture in the mask | 00:01 |
| dTal | hm okay maybe I'll start doing that | 00:01 |
| LjL | ndn[m], it didn't, trust me, what caused it was the humidity and the slight relaxation while waiting the canonical 15 minutes after being very tense as i was getting the vaccine :P | 00:02 |
| dTal | my psychology regarding covid has evolved rapidly lately | 00:03 |
| LjL | dTal, i'm not out to sell this spray, it just seems like much *less* of a hassle to me than wearing your P3 :P (which, again for the avoidance of doubt, i actually *do* think is likely more effective than this spray... really i just feel this is an extremely low-effort thing i can do) | 00:03 |
| LjL | if anything, some unknown Argentinians have managed to boost their friends' spray sales because i'm gullible to half-well-written abstracts | 00:04 |
| LjL | i'll live with that | 00:04 |
| dTal | the study looks pretty good actually, it's properly blinded and everything | 00:05 |
| LjL | you will find other studies as well regarding COVID, but the other ones are in vitro. still, they showed some activity | 00:05 |
| LjL | (unless there are also newer ones that i haven't seen) | 00:05 |
| dTal | this one finishes tomorrow: | 00:06 |
| dTal | https://clinicaltrials.gov/ct2/show/NCT04590365 | 00:06 |
| de-facto | my horror would be having to sneeze inside a mask | 00:06 |
| LjL | oh that's cool | 00:06 |
| de-facto | i probably would run out of the building and rip it off or such | 00:07 |
| LjL | i actually had that very tab open (for obvious reasons, because i needed to google it too) | 00:07 |
| LjL | but hadn't looked at it | 00:07 |
| LjL | de-facto, embrace the good | 00:07 |
| LjL | goo* | 00:07 |
| LjL | my fingers autocomplete... | 00:07 |
| dTal | I've noticed that the GVS mask actually propels droplets quite nastily sometimes | 00:08 |
| de-facto | fortunately did not happen yet despite me wearing one all days | 00:08 |
| dTal | I have to wear a cloth mask over it for source control | 00:09 |
| de-facto | yeah because the exhaling valve got smaller cross section than your mouth would have | 00:09 |
| LjL | dTal, the ingredients in the spray they're using in that one study are identical to the one in my spray by the way (more iota less kappa), the commercial name is different, but both have "Plus" so my guess is it's just different naming in different countries | 00:11 |
| LjL | i mean the study on clinicaltrials.gov run by swansea | 00:11 |
| LjL | anyway i think i'm having "i can't get it just before getting the vaccine, that would be maddening" syndrome again | 00:13 |
| de-facto | iota less kappa vs omicron? | 00:13 |
| de-facto | what are you talking about? :P | 00:13 |
| LjL | :P | 00:14 |
| LjL | don't make me type | 00:14 |
| LjL | c-a-r-a-g-e-n-a-n again | 00:14 |
| LjL | the treatment arm (verum Coldamaris plus, 0.12% iota-carrageenan plus 0.04% Kappa-Carrageenan in 0.5% saline) | 00:14 |
| de-facto | carrageenan | 00:14 |
| LjL | there are two types, i think in vitro they showed slightly different activity, my guess is it doesn't matter, but it's nice to be using the same thing they used in successful studies i guess | 00:15 |
| de-facto | how does it actually feel to sniff it? | 00:16 |
| LjL | very neutral, same as sniffing saline | 00:17 |
| LjL | it sometimes gives me a slight bit of headache, but i think it's just the action of inhaling hard, because i do have some degree of sinusitis | 00:17 |
| de-facto | oh so its not like a thick gel covering the mucus after it dried down or such? | 00:17 |
| LjL | no not at all | 00:17 |
| LjL | note the 0.12%+0.04%, those are small amounts diluted in a lot of saline | 00:17 |
| de-facto | yeah but doesnt it cover the mucus mechanically hence lowering the probability of virions to actually reach cells? | 00:19 |
| LjL | okay so, Coldamaris and the one i get (Lontax) are indeed the same thing, because both are based on a registered trademark "Carragelose", so the composition is going to be identical, the Lontax name is used in Italy and Germany, Coldamaris in the UK and Austria (those are the places i checked anyway) | 00:19 |
| de-facto | how does it influence smelling? | 00:19 |
| LjL | de-facto, that might be the mechanism of action but i'm not sure how much that *is* the mechanism of action, versus a plausible guess | 00:20 |
| LjL | it doesn't influence smell as far as i can tell | 00:20 |
| de-facto | nice | 00:21 |
| LjL | the Argentinian study doesn't seem to get into mechanism of action, but it cites the in vitro studies, those probably do | 00:21 |
| LjL | %paper Carrageenan-containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures | 00:22 |
| Brainstorm | LjL, 10 results out of 215207: Carrageenan-containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial cultures by Desiree Schütz et al, dated 2021-02-10 → https://www.doi.org/10.1152/ajplung.00552.2020 [... want %more?] | 00:22 |
| LjL | %paper SARS-CoV-2 in-vitro neutralization assay reveals inhibition of virus entry by iota-carrageenan | 00:22 |
| Brainstorm | LjL, 10 results out of 213359: SARS-CoV-2 in-vitro neutralization assay reveals inhibition of virus entry by iota-carrageenan by Martina Morokutti-Kurz et al, dated 2020-07-28 → https://biorxiv.org/cgi/content/short/2020.07.28.224733 [... want %more?] | 00:22 |
| LjL | %paper Iota-carrageenan and xylitol inhibit SARS-CoV-2 in cell culture | 00:23 |
| Brainstorm | LjL, 10 results out of 209374: Iota carrageenan and xylitol inhibit SARS-CoV-2 in Vero cell culture by Julio Cesar Vega et al, dated 2020-08-21 → https://biorxiv.org/cgi/content/short/2020.08.19.225854 [... want %more?] | 00:23 |
| LjL | (i've also tried finding xylitol mints by the way, but failed! i don't know why they don't seem to be a thing in Italy. there is gum, but i hate gum) | 00:23 |
| LjL | %paper Iota-carrageenan prevents the replication of SARS-CoV-2 on an in vitro respiratory epithelium model | 00:23 |
| Brainstorm | LjL, 10 results out of 215656: Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro by Martina Morokutti-Kurz et al, dated 2021-02-18 → https://www.doi.org/10.1371/journal.pone.0237480 [... want %more?] | 00:23 |
| LjL | these are the four cited studies | 00:23 |
| de-facto | i bought a nasal shower, its a bottle with saline solution to inject up each nostril separately and when i take a shower i also wash my nose (from the inside) with it in the hope to increase mucosal health by cleaning off all the dust etc | 00:24 |
| de-facto | its quite refreshing feeling afterwards very convenient | 00:24 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Pfizer´s PAXLOVID, a protease inhibitor, keeps its activity for all SARS-CoV-2 variants.biorxiv.org/content/10.110… pic.twitter.com/619kpNKkBn → https://twitter.com/Marc_Veld/status/1465822544011960325 | 00:24 |
| LjL | at a glance, i'm not seeing much discussion of the presumed mechanism of action in those studies | 00:25 |
| LjL | but it's really a glance | 00:25 |
| LjL | they put it into vero cells, it did something, they published :P | 00:26 |
| LjL | (just kidding) | 00:26 |
| LjL | (maybe) | 00:26 |
| LjL | de-facto, i did that nasal shower thing for a while, just make sure you use saline because some people who've done it with tap water have had nasty surprises | 00:27 |
| joerg | re ffp3 masks: a weird detail is, the certification doesn't even look at the fit and leakage, masks are tested with putty used to seal them 100% onto the dummy's face | 00:29 |
| joerg | at least that's what all the tests I seen looked like | 00:30 |
| joerg | maybe there's a separate test step specifically for leakage alone | 00:31 |
| LjL | yeah i didn't mention FFP masks because i always forget about which way those are, but while KN95 certification requires a fit test, N95 doesn't, it's up to the users to ensure proper fit. i guess FFP does it the N95 way | 00:31 |
| rpifan | yes someone that i knew knew someone who got a brain worm from tap water and died | 00:32 |
| LjL | rpifan, anywhere Florida? | 00:33 |
| LjL | or Texas? | 00:33 |
| de-facto | joerg, huh? i thought mask fit *is* part of the FFP certification process | 00:34 |
| joerg | I don't know for sure | 00:34 |
| joerg | probably there's no such thing like THE ffp cert process, it's likely several EN standards | 00:35 |
| de-facto | i think it may be defined in EN 149 | 00:36 |
| de-facto | https://de.wikipedia.org/wiki/Atemschutzmaske#Klassifikation_in_Europa | 00:36 |
| de-facto | %tr <de Eine Klassifikation wird nach der europäischen Norm EN 149 in drei Partikelfilterklassen vorgenommen. Zur Beurteilung dient die Gesamtleckage einer Maske, die sich aus Undichtigkeitsstellen am Gesicht, der Leckage am Ausatemventil (wenn vorhanden) sowie aus dem eigentlichen Filterdurchlass zusammensetzt. | 00:36 |
| rpifan | nop | 00:37 |
| Brainstorm | de-facto, German to English: A classification is carried out according to the European standard EN 149 in three particulate filter classes. For the assessment, the total leakage of a mask is composed of leaks on the face, the leakage on the exhalation valve (if available) and the actual filter passage. (MyMemory) [... want %more?] | 00:37 |
| Brainstorm | Updates for Andorra: +403 cases (now 17115) since 4 days ago — France: +49499 cases (now 7.8 million), +119 deaths (now 120116) since 14 hours ago — United Kingdom: +40831 cases (now 10.3 million), +161 deaths (now 145414) since 23 hours ago | 00:37 |
| LjL | all i know is between N95 and KN95 | 00:41 |
| LjL | https://smartairfilters.com/en/blog/whats-difference-between-n95-kn95-masks/ | 00:41 |
| LjL | "To be certified as a KN95 mask, the Chinese government requires the manufacturer to run a special mask fit test on real humans with ≤ 8% leakage. The N95 mask standard does not require manufacturers to run fit tests. This does not mean that fit tests aren’t helpful. Many hospitals and companies require their workers to be fit-tested. However, those are requirements of companies themselves, not for the US NIOSH certification on the mask." | 00:41 |
| LjL | that page also has a table (that you can find at several other places too) that compares requirements, although whether or not a human fit test must be performed is not stated in the table | 00:42 |
| LjL | rpifan, guess was based on https://en.wikipedia.org/wiki/Naegleriasis#Epidemiology | 00:43 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): The least vaccinated counties in the EU; higher infection rates coupled with high severe disease and deaths. pic.twitter.com/czlhh6hPmy → https://twitter.com/Marc_Veld/status/1465827873248403468 | 00:43 |
| de-facto | wow did not know that N95 is so loosely defined in comparison | 00:43 |
| de-facto | no bound in inward leakage? | 00:44 |
| de-facto | no airflowrate for inhalation resistance? | 00:45 |
| de-facto | almost cant believe that this is true | 00:45 |
| de-facto | oh at flow rate ok | 00:45 |
| LjL | do you realize that in practice these masks are all similar provided they are by the same manufacturer :P | 00:47 |
| LjL | like, 3M has a line of FFP2 and a line of N95 | 00:47 |
| LjL | i doubt they are actually different | 00:47 |
| de-facto | "To be certified as a KN95 mask, the Chinese government requires the manufacturer to run a special mask fit test on real humans with ≤ 8% leakage. The N95 mask standard does not require manufacturers to run fit tests." | 00:47 |
| LjL | on the other hand, KN95 nominally requires a fit test, but many KN95 masks are outright terrible with fit | 00:47 |
| LjL | yes, i posted that, i know what it says | 00:47 |
| de-facto | oh sorry LjL did not read your message above, was reading through the link you provided instead | 00:48 |
| LjL | maybe the reasoning in the N95 (and maybe FFP2) standards was that faces are different anyway, so a fit test should always be done by the wearer | 00:50 |
| LjL | and "certifying" them as "fit" might be misleading | 00:50 |
| de-facto | yeah with Asian faces that have more flat noses at the masks upper edge, hence most likely having much less emphasized leakage issues on the left and right sides of the nose at the masks upper edge (where that metal strip should help holding it in shape against the face) | 00:52 |
| de-facto | in comparison to European faces | 00:52 |
| de-facto | i think this is the single point where the effect of most masks probably could be increased the most: ensuring there is no leakage at the masks upper edge on the sides of the nose, possibly using a much stronger metal strip could help quite a bit | 00:54 |
| LjL | but then you'd saw into your nose | 00:54 |
| LjL | unless you also added a strip of foam | 00:55 |
| LjL | ... wait that's what 3M does! | 00:55 |
| LjL | (or let's just try to be more Asian) | 00:55 |
| * LjL starts punching himself on the nose | 00:55 | |
| de-facto | or even clamping them down with something like a plastic torus with a missing sector on its bigger radius, e.g. a C-shaped clamp holding it down left and right to the nose | 00:55 |
| de-facto | oh yeah that foam, it indeed helps a LOT | 00:55 |
| LjL | it would be beneficial if the nose could also still be able to breathe | 00:55 |
| de-facto | actually that is exactly what 3M does, its got that (non-open-pores) foam and a much stronger metal strip that actually holds its shape | 00:58 |
| de-facto | i have seen at work they also got some "classic" (K)N95 style ones with foam | 00:59 |
| de-facto | i assume it improves them quite a lot too | 00:59 |
| LjL | de-facto, some KF94s are also sold with foam to apply to them | 01:03 |
| LjL | the ones with the more Aura-type shape (but still different from Auras) | 01:03 |
| LjL | %title https://www.jpost.com/health-and-wellness/coronavirus/two-israeli-doctors-test-positive-for-omicron-covid-variant-687412 | 01:13 |
| Brainstorm | LjL, the URL could not be loaded | 01:13 |
| LjL | "Both doctors were fully vaccinated with three shots of the Pfizer coronavirus vaccine" | 01:13 |
| LjL | it doesn't say their conditions | 01:14 |
| LjL | 2Before entering isolation, the doctor had performed several catheterizations and attended at least two other large events. He was also in contact with the second cardiologist, in his 70s, who is now infected with the variant." so... enjoy Omicron, Israel ;( | 01:14 |
| de-facto | not good :/ | 01:16 |
| joerg | I had that idea of using tesamoll foam tape for improving masks. Then I got me the Draeger 1730 and they have it OOTB | 01:16 |
| de-facto | hopefully they will tell something about their disease trajectory | 01:16 |
| de-facto | thats a good idea joerg is it smooth enough for that? | 01:17 |
| LjL | i don't know where to get Dräger here | 01:18 |
| de-facto | i noticed they employ extra "soft" foam that easily can fill out the gaps without requiring too much pressure from the straps | 01:19 |
| joerg | there are two types, or actually 3: PE-foam open pore (classic), very soft, maybe too soft. Then PU-foam closed pore flat and white, very soft but just right, and profiled PU-foam (no idea which color) which is probably not suitable for that purpose | 01:19 |
| de-facto | so the closed pore PU is the best? | 01:20 |
| joerg | I'd think so, I tested none so far | 01:20 |
| joerg | also don't have any of the Tesamoll tapes at hand right now | 01:21 |
| de-facto | if its closed pores and soft enough it would be really convenient hence a good idea | 01:21 |
| joerg | https://amazon.de/tesamoll-Schaumstoffdichtung-Fenster-einfache-Qualit%C3%A4t/dp/B000VDD73S | 01:25 |
| joerg | there's several types now, I see https://amazon.de/-/en/tesamoll-Flexible-Draughts-Self-adhesive-Waterproof/dp/B0060V9FP4/ref=pd_sbs_1/262-7571750-8379017 | 01:26 |
| joerg | https://amazon.de/-/en/tesamoll-Polyethylene-Profile-Rubber-Seal/dp/B000QB303W/ref=pd_sbs_5/262-7571750-8379017 | 01:28 |
| Brainstorm | New from r/WorldNews: worldnews: Greece to fine people over 60 who have not been vaccinated → https://old.reddit.com/r/worldnews/comments/r61fdo/greece_to_fine_people_over_60_who_have_not_been/ | 01:30 |
| LjL | wow | 01:31 |
| Brainstorm | Updates for Netherlands: +22198 cases (now 2.7 million) since 21 hours ago | 01:39 |
| Brainstorm | New from BBC Health: Covid: Is it safe to hit the office Christmas party?: What is the chance that after-work drinks with colleagues will turn into a Covid superspreader event? → https://www.bbc.co.uk/news/health-59414343 | 01:58 |
| Brainstorm | New from r/WorldNews: worldnews: Shanghai halts 500 flights, issues closure order after 3 three local Covid cases → https://old.reddit.com/r/worldnews/comments/r625ul/shanghai_halts_500_flights_issues_closure_order/ | 02:08 |
| Brainstorm | New from COVID on Twitter: Prof. Jose-Luis Jimenez (@jljcolorado): In light of the fact that #OmicronIsAirborne, because all variants are #airborne, hand washing is not that important for COVID (though it is a good idea in general).Well fitting N95, ventilation & CO2 meters, filtration, distance, minimizing [... want %more?] → https://twitter.com/jljcolorado/status/1465864211117101062 | 03:14 |
| Dredd | So Israel didn't manage to shut all the gates before the Omicron got in? | 03:32 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): That's very good news. The bad news is our lack of testing readiness, a problem that has plagued this country since day 1 of the pandemic, and desperately needs to get fixed. Where is the abundant supply of free, rapid antigen tests? nytimes.com/2021/11/29/hea… [... want %more?] → https://twitter.com/EricTopol/status/1465874848844898311 | 03:51 |
| Brainstorm | New from The Indian Express: World: South Korea reports daily record of over 5,000 new Covid-19 infections → https://indianexpress.com/article/world/south-korea-covid-infections-7649989/ | 04:01 |
| xrogaan | Oh, look at that, data! https://www.reddit.com/r/Coronavirus/comments/r5ueps/first_stats_for_omicron_in_israel_protection_for/ | 04:18 |
| xrogaan | .title | 04:18 |
| Brainstorm | xrogaan: From www.reddit.com: First stats for Omicron in Israel: protection for vaccinated similar to Delta, twice as dangerous for unvaccinated : Coronavirus | 04:18 |
| xrogaan | granted, the article isn't in english. So us plebs will have to wait a little bit more. | 04:19 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): A friend highlighted that now there are antivirals. But I replied, Where? To the best of my knowledge, we have none in South Africa and it will most likely be like the vaccines, it will get hoarded and we will not get it when we need it the most @Merck @pfizer ??? → https://twitter.com/Tuliodna/status/1465882187182575617 | 04:19 |
| Brainstorm | Updates for United Kingdom: +40120 cases (now 10.3 million) since 11 hours ago — Netherlands: +56 cases (now 2.7 million) since 10 hours ago | 04:33 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): I will start sounding like @GretaThunberg - 'Blah, Blah, Blah' to all of the promises of the world leaders... They had promised many times vaccines, support, antivirals, etc. for poor countries in a pandemic and we are still waiting as the pandemic rages... [... want %more?] → https://twitter.com/Tuliodna/status/1465887507032252422 | 04:38 |
| sdfgsdfg | twice as dangerous for the unvaccinated ? shit | 05:01 |
| sdfgsdfg | protection for vaccinated similar to delta ? | 05:01 |
| xrogaan | I'll need more details on that. | 05:01 |
| sdfgsdfg | how vague and how stupid is that research honestly ? similar is a very helpful word | 05:02 |
| xrogaan | yeah, so, your ability to fight off the initial infection should remain good. | 05:02 |
| xrogaan | it's a title, not a research. | 05:02 |
| sdfgsdfg | unhelpful* | 05:02 |
| sdfgsdfg | everyone knows there would be at least some kind of protection against it but without knowing the exact details it's another hope trade | 05:03 |
| xrogaan | In the reddit comments, they talk about 90% protection. | 05:04 |
| sdfgsdfg | thats not bad at all | 05:05 |
| sdfgsdfg | 90% protection in a world where all vaccine immunity have already waned | 05:05 |
| sdfgsdfg | that is surreal | 05:05 |
| xrogaan | R1.3, which is similar to delta. 2.4 times the severity though (if people do get sick, it's much worse). | 05:05 |
| xrogaan | no they didn't. | 05:06 |
| sdfgsdfg | oh so they last forever or ? | 05:06 |
| sdfgsdfg | how long do they last then | 05:06 |
| xrogaan | don't know ¯\_(ツ)_/¯ | 05:07 |
| xrogaan | What seems to be the issue with Omicron is that strain "cares" less about prior infections. | 05:07 |
| sdfgsdfg | it's 3 months | 05:07 |
| xrogaan | are you pulling that from a hat? | 05:08 |
| sdfgsdfg | I remember several papers here mentioning the 3-4 months mark for at least fifty percent reduction | 05:09 |
| xrogaan | Your protection against infection "waines" over time, but you're still less likely to develop severe disease or require hospitalization. | 05:10 |
| sdfgsdfg | but you can find other papers that mention a 6 months mark plus some memory cell magic | 05:10 |
| xrogaan | Being exposed to the disease will be a form of "booster" for your immune system. | 05:10 |
| sdfgsdfg | politics in science ¯\_(ツ)_/¯ | 05:10 |
| xrogaan | waine or wane? | 05:10 |
| xrogaan | wane is the word, right? | 05:10 |
| sdfgsdfg | ye | 05:10 |
| xrogaan | If you're never exposed to the disease in 3 months, then you'd probably need a booster. But it's not critical for most of the population, rather more important for the older folks. | 05:13 |
| xrogaan | https://www.virology.ws/2021/08/19/are-covid-19-vaccine-boosters-needed/ | 05:14 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Fully vaccinated = 3 shots. → https://twitter.com/EricTopol/status/1465899574673821704 | 05:35 |
| Brainstorm | Updates for Belgium: +16566 cases (now 1.8 million), +49 deaths (now 27015), +106897 tests (now 24.7 million) since a day ago | 05:35 |
| Brainstorm | Updates for India: +1203 cases (now 34.6 million), +191 deaths (now 469247) since 6 hours ago | 06:00 |
| Brainstorm | Updates for Thuringen, Germany: +3904 cases (now 215048), +40 deaths (now 5013) since a day ago — Mecklenburg-Vorpommern, Germany: +1570 cases (now 72151), +5 deaths (now 1335) since a day ago — Germany: +68676 cases (now 5.9 million) since 20 hours ago — Inner Mongolia, China: +91 cases (now 750) since a day ago | 06:38 |
| Brainstorm | New from r/WorldNews: worldnews: Germany's designated chancellor backs COVID vaccine mandate → https://old.reddit.com/r/worldnews/comments/r689bv/germanys_designated_chancellor_backs_covid/ | 07:46 |
| Brainstorm | New from MedicineNet: (news): Pfizer to Seek FDA Approval of Boosters for Teens Ages 16-17 → http://www.medicinenet.com/script/main/art.asp | 08:04 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Germany Vaccine Mandate: Incoming German Chancellor Olaf Scholz reportedly supports the introduction of a vaccine mandate in Germany. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/r690nc/germany_vaccine_mandate_incoming_german/ | 08:23 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | December 01, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/r69o0t/daily_discussion_thread_december_01_2021/ | 09:01 |
| Brainstorm | New from COVID on Twitter: Jeffrey Barrett (@jcbarret): Astonished at @BBCr4today interview w/pub magnate Hugh Osmond. Fair enough to ask him about effect of restrictions on his business, but he made misleading statements about vaccines, transmission patterns, risk to kids and Omicron without pushback. → https://twitter.com/jcbarret/status/1465957797221351424 | 09:20 |
| Brainstorm | New from BMJ: Covid-19: Poorly controlled asthma increases risk of hospital admission among children sixfold, finds study: Children with poorly controlled asthma are at a higher risk of being admitted to hospital with covid-19 and should therefore be prioritised for vaccination, according to researchers who analysed data... → http://www.bmj.com/content/375/bmj.n2959.short | 09:58 |
| Brainstorm | New from r/WorldNews: worldnews: Japan starts booster COVID vaccinations → https://old.reddit.com/r/worldnews/comments/r6agmg/japan_starts_booster_covid_vaccinations/ | 10:07 |
| Brainstorm | New from The Indian Express: World: Omicron Covid-19 variant: top international developments today → https://indianexpress.com/article/world/omicron-covid-19-variant-top-developments-today-7650519/ | 10:16 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Rotarix, rotavirus vaccine, live, Immunization;Rotavirus Infections, Date of authorisation: 21/02/2006, Revision: 38, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/rotarix | 10:35 |
| Brainstorm | Updates for Germany: +68680 cases (now 5.9 million) since 18 hours ago | 10:40 |
| Brainstorm | New from StatNews: A reason for optimism on Omicron: Our immune systems are not blank slates: Even if the news with Omicron is bad, there’s good reason to think people with some immune protections may avoid the worst of what Covid infections can do to immunologically… → https://www.statnews.com/2021/12/01/a-reason-for-optimism-on-omicron-our-immune-systems-are-not-blank-slates/ | 10:45 |
| Brainstorm | New from BBC Health: (news): Covid: Omicron may require 'very stringent response', say Sage scientists → https://www.bbc.co.uk/news/health-59484322 | 10:54 |
| Brainstorm | New from ProPublica: “They Took Us Away From Each Other”: Lost Inside America’s Shadow Foster System: by Lizzie Presser , photography by Elinor Carucci for The New York Times ] ProPublica is a nonprofit newsroom that investigates abuses of power. [... want %more?] → https://www.propublica.org/article/they-took-us-away-from-each-other-lost-inside-americas-shadow-foster-system#1176911 | 11:13 |
| Brainstorm | New from BMJ: Extensive ecchymosis and symptomatic anaemia: These are large atraumatic ecchymoses on the legs of a patient in her 70s (fig 1) who was admitted to hospital as an emergency with weakness and syncope.Blood tests showed low levels of haemoglobin... → http://www.bmj.com/content/375/bmj.n2547.short | 11:22 |
| Brainstorm | Updates for Poland: +29076 cases (now 3.6 million), +570 deaths (now 84153), +92732 tests (now 24.4 million) since 23 hours ago | 11:30 |
| genera | that seems to be behind a paywall | 11:44 |
| Brainstorm | New from COVID on Twitter: Covid Fact Check UK (@fact_covid): Most experts seem to agree that lab tests in the coming weeks will show some loss of vaccine protection against mild & moderate disease due to Omicron. We already saw this with Delta.But there’s reason to believe that strong protection against severe [... want %more?] → https://twitter.com/fact_covid/status/1465998932249657347 | 12:10 |
| Brainstorm | Updates for Nepal: +285 cases (now 821651), +3 deaths (now 11529), +10919 tests (now 4.6 million) since 23 hours ago | 13:03 |
| Brainstorm | New from r/WorldNews: worldnews: The South African scientists tracking the new coronavirus variant believe it probably evolved in a patient with HIV/Aids with a chronic Covid-19 infection. → https://old.reddit.com/r/worldnews/comments/r6cxwp/the_south_african_scientists_tracking_the_new/ | 13:16 |
| Brainstorm | New from The Atlantic: What Makes a Vaccine’s Protection Last?: The Johnson & Johnson vaccine, perhaps more than any other COVID shot, knows what it is to be bullied by the American public. Since the spring, the shot’s been roasted, and roasted, and roasted [... want %more?] → https://www.theatlantic.com/science/archive/2021/12/vaccine-durability-annual-covid-boosters/620863/ | 13:25 |
| Brainstorm | New from ECDC: Epidemiological update: Omicron variant of concern (VOC) – data as of 1 December 2021 (12.00): As of 1 December 2021, and since 30 November 2021, 15 additional SARS-CoV-2 Omicron VOC cases have been confirmed, bringing the total to 59 confirmed cases. → https://www.ecdc.europa.eu/en/news-events/epidemiological-update-omicron-data-1-december-2021 | 13:35 |
| Brainstorm | New from COVID on Twitter: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): The correlation between “Pandemic over” takes and “masks are tyranny” is .99 → https://twitter.com/fitterhappierAJ/status/1466026168033947652 | 13:54 |
| Brainstorm | New from Science-Based Medicine: Omicron: is the latest variant of concern. It's too early to know what this means, but there is reason for concern. The post Omicron first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/omicron/ | 14:03 |
| Brainstorm | New from The Indian Express: World: Air travelers to US set to face tougher Covid-19 testing → https://indianexpress.com/article/world/us-air-travel-omicron-covid-19-testing-7651150/ | 14:23 |
| Guest23 | Wow | 14:25 |
| Brainstorm | New from The Indian Express (Health): Health: Covid long-haulers may experience abnormal breathing, chronic fatigue: Study → https://indianexpress.com/article/lifestyle/health/covid-long-haulers-may-experience-abnormal-breathing-chronic-fatigue-study-7649032/ | 14:33 |
| Brainstorm | Updates for Switzerland: +15229 cases (now 1.0 million) since 23 hours ago — Germany: +69420 cases (now 5.9 million) since 22 hours ago — United Kingdom: +40281 cases (now 10.3 million) since 21 hours ago | 14:37 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: COVID misinformation has reached young minds. A Johns Hopkins program seeks to reverse the damage. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/r6fe6q/covid_misinformation_has_reached_young_minds_a/ | 15:11 |
| Brainstorm | New from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): Such immune impairments in HIV infected individuals make it possible for SARS-CoV-2 to replicate for an extended time period, accumulating mutations. (4/)medrxiv.org/content/10.110… → https://twitter.com/VirusesImmunity/status/1466048123491524613 | 15:21 |
| Brainstorm | New from EMA: What's new: PIP: Opinion/decision on a Paediatric investigation plan (PIP): Human immunoglobulin G2 isotype antibody to IL-33R, decision type: , therapeutic area: , PIP number: P/0055/2020 → https://www.ema.europa.eu/en/medicines/human/paediatric-investigation-plans/emea-002515-pip01-18 | 15:30 |
| Brainstorm | New from EMA: News and press releases: Increase in manufacturing capacity for COVID-19 vaccine from AstraZeneca, CHMP, 01/12/2021: EMA’s human medicines committee (CHMP) has approved a new site to manufacture Vaxzevria (previously COVID-19 Vaccine AstraZeneca) finished product. The... → https://www.ema.europa.eu/en/news/increase-manufacturing-capacity-covid-19-vaccine-astrazeneca | 15:40 |
| Brainstorm | Updates for Canada: +2472 cases (now 1.8 million), +21 deaths (now 29745) since 23 hours ago | 16:29 |
| genera | " The site, operated by WuXi Biologics, is located in Leverkusen, Germany | 16:42 |
| Brainstorm | New from COVID on Twitter: Zach Brennan (@ZacharyBrennan): $MRNA loses latest battle in key vaccine delivery patent fight as federal appeal falls flat (and as NIH battle is ongoing) endpts.com/moderna-loses-… → https://twitter.com/ZacharyBrennan/status/1466068793390739464 | 16:47 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): More on this:—Omicron hasn't shown it can compete w/ Delta (that'll be tough) —Beta is the variant with the most known immune evasive property. When the original Wuhan strain vaccine was tested against a Beta-specific one for neutralizing antibodies there was [... want %more?] → https://twitter.com/EricTopol/status/1466075232976789510 | 17:06 |
| Brainstorm | New from COVID on Twitter: Trevor Bedford (@trvrb): Note also that high immune escape, lower intrinsic transmissibility is not necessarily a good thing. Higher immune escape places previously infected and vaccinated individuals more at risk. 17/18 → https://twitter.com/trvrb/status/1466076807698862080 | 17:16 |
| Brainstorm | New from ClinicalTrials.gov: (news): Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms → https://clinicaltrials.gov/ct2/show/NCT05139433 | 17:25 |
| Brainstorm | New from ClinicalTrials.gov: (news): Non-invasive Tools to Better Diagnose Invasive Aspergillosis Infections in ICU Patients. → https://clinicaltrials.gov/ct2/show/NCT05138666 | 17:35 |
| Brainstorm | Updates for Netherlands: +18571 cases (now 2.7 million), +45 deaths (now 19908) since 23 hours ago | 17:37 |
| Brainstorm | New from ClinicalTrials.gov: (news): Yogic Breathing and Guided Meditation for Long Covid Symptoms → https://clinicaltrials.gov/ct2/show/NCT05139979 | 17:54 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Wow! Graphics and animations of SARS-CoV-2nytimes.com/interactive/20… → https://twitter.com/Marc_Veld/status/1466089890551062542 | 18:04 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Ok, tonight I should be calmer when South Africa report 8,561 new #COVID19 in the last 24-hours. Double as yesterday and 16.5% positivity rate... Please @rid1tweets @sugan2503 @Rajeev_The_King can you provide a more detailed epi analysis #Omicron → https://twitter.com/Tuliodna/status/1466093862011691010 | 18:23 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Let me please repeat my plea to governments, financial institutions & billionaires to help South Africa and Africa. Should we wait for hospitalization, death & vaccine neutralization results to act? Have we not learned that quick response is what controls [... want %more?] → https://twitter.com/Tuliodna/status/1466096654453465093 | 18:32 |
| Brainstorm | Updates for United Kingdom: +601 cases (now 10.3 million) since 21 hours ago | 18:39 |
| Brainstorm | New from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 30 novembre 2021: Ulteriori misure urgenti in materia di contenimento e gestionedell'emergenza epidemiologica da COVID-19 in occasione dell'eventointernazionale denominato «Rome MED 2021 - Mediterranean Dialogues».(21A07133) → http://www.gazzettaufficiale.it/eli/id/2021/12/01/21A07133/SG | 19:00 |
| Brainstorm | Updates for Italy: +15073 cases (now 5.0 million), +103 deaths (now 133931), +573775 tests (now 119.9 million) since a day ago | 19:04 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): WHO COVID-19 media briefing.-No data of reduced vaccine efficacy to Omicron. (this is even not an issue with Beta, the most evasive VoC).-No data Omicron can compete with Delta (that is difficult)youtu.be/Z1iAd5m_qQk → https://twitter.com/Marc_Veld/status/1466105136401596420 | 19:10 |
| Brainstorm | New from NPR: The omicron variant has been found in 23 countries: More should be known about the transmissibility and severity of the new variant in "days, not necessarily weeks," a senior World Health Organization scientist says. → https://www.npr.org/sections/coronavirus-live-updates/2021/12/01/1060477609/the-omicron-variant-has-been-found-in-23-countries | 19:29 |
| Brainstorm | New from r/WorldNews: worldnews: Co-founder of Christian TV network that railed against vaccines dies of Covid-19 | Coronavirus → https://old.reddit.com/r/worldnews/comments/r6lex1/cofounder_of_christian_tv_network_that_railed/ | 19:47 |
| Brainstorm | New from StatNews: First case of Omicron coronavirus variant identified in the U.S.: U.S. health officials on Wednesday reported the country’s first case of the Omicron variant of the coronavirus, in a person in California who had a recent case of Covid-19. → https://www.statnews.com/2021/12/01/first-case-omicron-coronavirus-variant-identified-united-states/ | 20:06 |
| Brainstorm | Updates for Spain: +10536 cases (now 5.2 million), +28 deaths (now 88080) since 22 hours ago — Germany: +78855 cases (now 5.9 million), +588 deaths (now 102482) since 23 hours ago | 20:07 |
| Brainstorm | New from Politico: How Trump’s ‘America First’ edict delayed the global COVID fight: With Omicron emerging in countries deprived of vaccines, the failure to develop a strategy to inoculate the world looms large. → https://www.politico.com/news/2021/12/01/trump-america-first-covid-523604 | 20:16 |
| Brainstorm | New from Politico: Coronavirus: Germany to tighten coronavirus restrictions → https://www.politico.eu/article/germany-to-tighten-coronavirus-restrictions/ | 20:26 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Today's revelation: Trump PCR+ on 9/26, debated Biden on 9/29, felt sick on 10/1. Prophylaxing Biden would have been merited, as I suggested then.Just imagine if Biden had gotten sick. Amazing how SARSCoV2 can change history on big and small [... want %more?] → https://twitter.com/michaelzlin/status/1466125963402514432 | 20:36 |
| LjL | %cases germany | 20:50 |
| Brainstorm | LjL: Germany has had 5.9 million confirmed cases (7.1% of all people) and 102482 deaths (1.7% of cases) as of 43 minutes ago. 83.8 million tests were done (7.1% positive). 59.4 million were vaccinated (71.4%). +78855 cases, +588 deaths since 23 hours ago. See https://corona.rki.de/ | 20:50 |
| de-facto | COVID Germany (RKI) 2021-12-01: +67186 cases; +446 Deaths, weekly incidence 442.9/100k, 4690 ICUs, 2435 ventilated, ICUs available: low care 803, high care 1513, ecmo 304 | 20:59 |
| LjL | yeah what was actually after was just the offloop curve but i forgot the bot would give me rki.de instead | 21:00 |
| Brainstorm | New from COVID on Twitter: Prof Peter Hotez MD PhD (@PeterHotez): Second, looking at the virus sequence in both the S and N proteins I think this new omicron won’t displace or outcompete delta. Instead I see a possible twin epidemic or syndemic unfolding… → https://twitter.com/PeterHotez/status/1466129844215898113 | 21:05 |
| Brainstorm | Updates for Bangladesh: +282 cases (now 1.6 million), +2 deaths (now 27983), +18851 tests (now 10.9 million) since a day ago | 21:09 |
| Arsanerit | Is the German 5th wave actually flattening or is it just the labs running out of testing capacity? | 21:13 |
| Brainstorm | New from CIDRAP: News Scan for Dec 01, 2021: COVID vaccine booster efficacy COVID-19 and asthma → https://www.cidrap.umn.edu/news-perspective/2021/12/news-scan-dec-01-2021 | 21:14 |
| de-facto | Arsanerit, very good question | 21:33 |
| Brainstorm | New from Contagion Live: First Omicron Case in the United States Reported: The first Omicron COVID-19 case was discovered in California. The patient, who traveled from South Africa, has since recovered. → https://www.contagionlive.com/view/first-omicron-case-in-the-united-states-reported | 21:33 |
| Brainstorm | Updates for France: +48161 cases (now 7.8 million), +92 deaths (now 120208) since 20 hours ago — India: +9866 cases (now 34.6 million), +476 deaths (now 469532) since 21 hours ago | 21:34 |
| de-facto | hmm they stopped publishing the number of samples in queue for being processed in labs?! | 21:36 |
| de-facto | its all "0" since week 36 | 21:36 |
| LjL | Arsanerit, de-facto: i'd say look at the deaths to know | 21:38 |
| Arsanerit | deaths with 4-6 weeks delay I suppose? | 21:42 |
| Brainstorm | New from CIDRAP: Severe COVID tied to high risk of death, mostly by other causes, within year: Mary Van Beusekom | News Writer | CIDRAP News Dec 01, 2021 Severe COVID-19 may bring more than twice the risk of dying within a year. → https://www.cidrap.umn.edu/news-perspective/2021/12/severe-covid-tied-high-risk-death-mostly-other-causes-within-year | 21:43 |
| de-facto | yeah deaths have a lot of reporting delay at the tail | 21:46 |
| de-facto | ICU data is pretty up-to-date | 21:46 |
| de-facto | this here https://www.intensivregister.de/#/aktuelle-lage/zeitreihen | 21:46 |
| de-facto | with up-to-date i mean almost no reporting delay, it has of course some delay to infections (quite a lot probably) | 21:47 |
| Arsanerit | Wow Bayern. | 21:50 |
| de-facto | indeed BY is worst | 21:52 |
| de-facto | (relative to its past) | 21:52 |
| Arsanerit | In particular compared to previous waves. | 21:52 |
| de-facto | Used covid ICU per 100k capita in decreasing sequence: SN 14.27, TH 10.14, BY 8.1, ... | 21:55 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): The tweet below was from yesterday! Calmily please compare the number of tests, new cases, and positivity rate... Today: A total of 51,977 tests were conducted in the last 24hrs, with 8,561 new cases, which represents a 16.5% positivity rate. Is that [... want %more?] → https://twitter.com/Tuliodna/status/1466149856708288515 | 22:02 |
| de-facto | https://ibz-shiny.ethz.ch/covid-19-re-international/ choose "South Africa" then in regions "Gauteng" | 22:17 |
| de-facto | data for SA cases (including regions like Gauteng) at https://raw.githubusercontent.com/covid-19-Re/dailyRe-Data/master/ZAF-estimates.csv | 22:21 |
| de-facto | sources at https://github.com/covid-19-Re/dailyRe-Data | 22:21 |
| de-facto | upstream https://github.com/dsfsi/covid19za/tree/master/data | 22:27 |
| de-facto | "Data Science for Social Impact Research Group @ University of Pretoria" | 22:28 |
| de-facto | https://dsfsi.github.io/covid19za-dash/ | 22:29 |
| de-facto | https://dsfsi.github.io/covid19za-dash/ | 22:30 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Our covid times :-(by @mluckovichajc pic.twitter.com/cdbbpHesuD → https://twitter.com/EricTopol/status/1466156826253168644 | 22:31 |
| Arsanerit | Would it be accurate to say that there are three choices on dealing with the pandemic: vaccination (mandatory if need be), lockdown, or acceptance? Or a combination of those three of course (for example, lockdown until vaccination threshold reached). Acceptance meaning accepting possibly hundreds of thousands of deaths and months or years of overloaded hospitals. | 22:35 |
| de-facto | acceptance would lead to hospitals closing down due to personnel running away | 22:38 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): In this thread from June, I pushed for boosting J&Jers. (As we know, they can now, but only after dying at higher rates than Pfizer and Moderna.)I also laid out medium and worst-case scenarios. Both came true [... want %more?] → https://twitter.com/michaelzlin/status/1466158842316607493 | 22:41 |
| Arsanerit | I seem to recall having read that in The Netherlands and Sweden old people who are unlikely to survive wouldn't be put on life support to begin with; I think in the first wave many residents in Swedish care homes died in those homes, never even reaching a hospital. Meaning: if one declares that patients over 80 are left to die, hospitals might not get overrun. | 22:42 |
| Arsanerit | Why are reported deaths in Sweden so low? | 22:44 |
| Arsanerit | Seems to be around 5 per day recently, and less than 10 per day since September http://offloop.net/covid19/?default=Sweden&cumulative=no&smooth=yes&leftTrim=600&legacy=no | 22:46 |
| Arsanerit | What is Sweden doing better than Norway or Finland? http://offloop.net/covid19/?default=Sweden;Denmark;Norway;Finland&byPopulation=yes&cumulative=no&smooth=yes&leftTrim=600&legacy=no | 22:48 |
| Brainstorm | New from COVID on Twitter: BNO Newsroom (@BNODesk): EU member states should discuss "mandatory vaccination" against COVID-19, European Commission President Ursula von der Leyen says → https://twitter.com/BNODesk/status/1466160978282827782 | 22:50 |
| spokojni[m] | We're done :( | 22:56 |
| spokojni[m] | It's biological war, we're in | 22:56 |
| Arsanerit | on which side are we? | 22:56 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): 2 new large cohort assessments of effectiveness of different vaccines over time, + DeltaVeterans nejm.org/doi/full/10.10…NY Statenejm.org/doi/full/10.10… pic.twitter.com/0u9vKqWIN7 → https://twitter.com/EricTopol/status/1466165459779145730 | 23:09 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): 24-week effectiveness of BNT and mRNA-1273 vaccines. Risk of Covid-19 outcomes was low after vaccination, risks were lower with mRNA-1273 than with BNT162b2. This pattern was consistent across periods marked by alpha- and delta-variant predominance.nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/1466168917919997953 | 23:18 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): In a prospective study >35,000 people with Pfizer or AZ vaccination, 27% with Prior Covid medrxiv.org/content/10.110…—3 shots are "essential to maintain protection" for people without Prior Covid —Most durable protection was from hybrid immunity: Prior Covid [... want %more?] → https://twitter.com/EricTopol/status/1466169648601133056 | 23:28 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated PersonsShorter infection period after vaccination. Viral loads not really known: assessed by Ct, which are quite similar, with expected lower values for delta infection.nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/1466173463891255300 | 23:37 |
| Brainstorm | Updates for Canada: +2953 cases (now 1.8 million), +20 deaths (now 29753) since 23 hours ago — United Kingdom: +47995 cases (now 10.3 million) since 23 hours ago | 23:38 |
| Brainstorm | New from COVID on Twitter: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): fully vaccinated with three or two doses? twitter.com/GyanCMehta/sta… → https://twitter.com/fitterhappierAJ/status/1466176103891017732 | 23:47 |
Generated by irclog2html.py 2.17.0 by Marius Gedminas - find it at https://mg.pov.lt/irclog2html/!