| dTal | for me, the worst part of getting my third jab was standing in line for 2 hours | 00:01 |
|---|---|---|
| Tuvix | Varients are the big reason the booster was recommended, and there is a notable difference there, as a UK technical briefing recently was pretty good at highlighting specifically for Omicron. | 00:01 |
| xrogaan | dTal: There were two lines: one for moderna and one for pfizer. Moderna was empty and I just walked in. | 00:02 |
| Tuvix | It could well be that an Omicron-updated booster provides more protection against a new varient, but we'll have to reserve judgement if/until that becomes a reality since it's largely speculation at this point. Before Delta few were predicting 2 varients each with so much more spread than the prior. | 00:02 |
| dTal | all the same, there's no reason a vaccine has to target just one variant. It's strictly a win if the next jab covers all the variants we've seen so far | 00:03 |
| Tuvix | Right, and that was, as I understand it, why the alpha/beta vaccine updates never went anywhere; it wasn't notably better at protection, certainly not enough to justify a whole new production run and the logistics of getting new boosters in people. | 00:05 |
| xrogaan | So we may get sick but, from what I've read, it wouldn't be as bad as requiring hospitalization. Booster helps prevent infection, so that weaker people (either due to their condition or temporary affliction) have less chances to land in the hospital. That was a good call, as omicron spreads like wildfire. | 00:05 |
| xrogaan | But we can't booster-shot the population of the earth every 6 months. That's not doable. | 00:05 |
| Tuvix | xrogaan: Huge numbers are dying in especially the unvaccinated parts of the US. We also don't know what the next varient will bring, which could turn out to be worse for the unboosted. Or for example, an updated booster may become something similar to seasonal flu where we target the most prevalant COVID varients spreading at the time predicted to do the most harm. | 00:06 |
| Tuvix | In the US anyway, more of the younger 3 age groups (the under 40's) were actually dying in *greater* numbers during the Delta wave during summer, despite the peak of Delta having a lot less deaths per-day. | 00:07 |
| xrogaan | So, two things: the covid vaccine is somewhat mandatory. Not legally, but business will want their staff to be vaccinated. That is different than a flu-vaccine once per year. | 00:08 |
| Tuvix | I put this chart together from CDC data (sources included, just remove the spaces due to imgur handling the links badly if you'd like to poke at it more) but it's clear that, while the older age-groups saw a reduciton in death figures, younger groups have fared less well during Delta: https://imgur.com/a/TsumLeL | 00:08 |
| xrogaan | Second, and forgive me, but I have low empathy towards the willful unvaccinated. I just don't worry about their health. I have family members who do not want to vaccinate, and they all have a moronic excuse. | 00:10 |
| xrogaan | yeah, being young has never prevented anybody from being sick. | 00:13 |
| xrogaan | I don't know from where that idea came from. | 00:13 |
| Tuvix | Well, the concerning part of that data is that it shows the younger groups dying MORE while the older groups are dying less, and there's less total detah in Delta as compared to the prior winter (probably alpha varient in the US) | 00:13 |
| Tuvix | Younger groups are also, genrally, less well vaccinated as a whole, and tend to socialize more (work, outings, parties, etc) than the older groups shown. | 00:14 |
| Tuvix | To be clear, younger groups dying more in Delta's wave then from the prior winter. | 00:15 |
| xrogaan | Alright, you're using those words like the journalists. What do you mean by young? | 00:15 |
| Tuvix | Older groups still see more death vs. the young, but that group saw improved odds during Delta, while the younger group saw worsening odds, respective to those same groups 8 months prior. | 00:16 |
| xrogaan | is it under 30? 40? | 00:16 |
| Tuvix | xrogaan: Did you check out my link? I clearly broke it down into 7 age-groups. | 00:16 |
| Tuvix | I also linked the CDC data if you want to explore the data-set more completely on your own. | 00:16 |
| Tuvix | Compare, for example, Jan/Sept (about the peak of both surge) between the top vs 2nd chart. Note the clear difference where all 3 of the younger age-groups do worse in Sept vs. Jan. while all 3 of the highest age-groups do better (50-64 are more similar for overall impact, though I grouped them with the older chart as they fit better there age-wise, and messed up my scale too much for the younger | 00:19 |
| Tuvix | grouping.) | 00:19 |
| Tuvix | 30-39 group died more than twice as much during the worst of the Delta surge vs. the previous winter. Vaccines were, in the US, widely available by then, so anyone who wanted one had the chance to seek it. | 00:19 |
| xrogaan | I see over 10k death for 50+? | 00:20 |
| xrogaan | I'm too tired to make sense of graphs | 00:20 |
| LjL | xrogaan, i find it interesting that in the 50-to-84 graph, the scales are tipped completely between the 2020 and the 2021 wave | 00:23 |
| LjL | december 2020, 85+ were dying the most | 00:23 |
| LjL | september 2021, the 50-64 were dying the most | 00:24 |
| LjL | does look like vaccine effect to me, that | 00:24 |
| LjL | as to the graph for the 0-to-39, i can just say that the 30-39 die *a lot, yikes*. yes the scale is different from the other graph | 00:24 |
| xrogaan | I may be cynical, but old people are more fragile (85+). Could it be that those who would have succumbed did so in 2020? | 00:25 |
| xrogaan | Not necessarily from disease, mind you. | 00:25 |
| LjL | i think that could be partly an effect but the inversion looks too blatant to just be explained by that | 00:28 |
| Tuvix | On top of that, many care facilities went into very strict lockdown and testing procedures early in the pandemic, and I have family at such a facility. | 00:29 |
| Brainstorm | New from The Lancet (Online): Lulu Bravo, Igor Smolenov, Htay Htay Han, Ping Li, Romana Hosain, Frank Rockhold, Sue Ann Costa Clemens, Camilo Roa, Charissa Borja-Tabora, Antoinette Quinsaat, Pio Lopez, Eduardo López-Medina, Leonardo Brochado, Eder A Hernández, Humberto Reynales, Tatiana [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00055-1/fulltext | 00:36 |
| xrogaan | Lulu Bravo, MD <- This is a great name. | 00:45 |
| Brainstorm | New from The Lancet (Online): [Comment] Trimeric S protein COVID-19 vaccine needs to find its place: When the race towards the development of vaccines against COVID-19 began in early 2020, many of the front-line candidates were based on the spike (S) protein of SARS-CoV-2, coupled with an [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00096-4/fulltext | 00:46 |
| Brainstorm | New from r/WorldNews: worldnews: Austria parliament approves mandatory Covid vaccination → https://old.reddit.com/r/worldnews/comments/s8x1at/austria_parliament_approves_mandatory_covid/ | 01:33 |
| Brainstorm | New from BBC Health: Covid: NHS in push to vaccinate the final four million: Hard-to-reach groups – from rough sleepers to fairground workers – are being targeted in a final vaccine push. → https://www.bbc.co.uk/news/health-60055436 | 03:08 |
| oerheks | 4m .. | 03:25 |
| tyche | offer to pay them | 03:34 |
| tyche | is it really soo hard | 03:34 |
| Brainstorm | New from r/Science: science: In the absence of a vaccination program, there would have been approximately 1.1 million additional COVID-19 deaths and more than 10.3 million additional COVID-19 hospitalizations in the U.S. by November 2021. → https://old.reddit.com/r/science/comments/s8z4f6/in_the_absence_of_a_vaccination_program_there/ | 03:38 |
| oerheks | oh those statistics .. say statistics say nothing. | 03:49 |
| Brainstorm | New from This Week In Virology: TWiV 855: T time with Alessandro Sette: Alessandro Sette returns to TWiV to discuss the observation that SARS-CoV-2 vaccination induces T cells that are able to cross-recognize variants Alpha to Omicron. → https://www.microbe.tv/twiv/twiv-855/ | 03:49 |
| LjL | tyche, i think i read of at least one country that actually did that | 03:49 |
| oerheks | Belgium .. people just needed to change mobile number to get another shot/payment | 03:50 |
| LjL | though i think unless you did that from the start, people who've gotten the vaccine without getting paid for it would be somewhat upset :P | 03:50 |
| LjL | oerheks, ouch | 03:51 |
| LjL | was the payment more than a SIM costs? :P | 03:51 |
| oerheks | According to his testimony, he received eight jabs and was paid between €100 - €150 ($113 - $170) | 03:52 |
| LjL | oerheks, wait, that said he was being paid *by anti-vaxxers* to get a vaccine passport for that | 03:53 |
| LjL | the state wasn't paying him | 03:53 |
| Brainstorm | New from r/WorldNews: worldnews: Tennis star Andrei Rublev has revealed he was allowed into Australia with Covid → https://old.reddit.com/r/worldnews/comments/s90f9u/tennis_star_andrei_rublev_has_revealed_he_was/ | 04:46 |
| tyche | national tv news, said 2x 'most of the deaths are the unvaccinated' | 04:58 |
| tyche | and dean of Brown PH school, peak isn't far away or some such, then how biden, promises war don't worry | 04:59 |
| redempt1on | Whaddup G's | 04:59 |
| redempt1on | Tugger. | 04:59 |
| redempt1on | COVID IS OVER! | 04:59 |
| redempt1on | omicron is just a cold | 04:59 |
| redempt1on | and nearing end of spread | 04:59 |
| redempt1on | We will then have natural immunity | 05:00 |
| redempt1on | Vaccines bogus, faulty at best | 05:00 |
| de-facto | hospitals usually dont fill with "just a cold" hence Omicron is not just a cold | 05:14 |
| de-facto | most places still have rising daily new infections with Omicron | 05:15 |
| de-facto | Omicron demonstrated that SARS-CoV-2 got seroevasive capabilities, meaning immunity from previous Delta infection (or even older mutants) does not protect from Omicron infection | 05:16 |
| de-facto | Vaccines prevent 9 out of 10 hospitalizations even with Omicron, so that demonstrates they work pretty well | 05:16 |
| Brainstorm | New from r/WorldNews: worldnews: Covid hits Argentina's research base in Antarctica → https://old.reddit.com/r/worldnews/comments/s91muu/covid_hits_argentinas_research_base_in_antarctica/ | 05:33 |
| Brainstorm | New from Science-Based Medicine: An Open Letter to ZDoggMD: I hope you'll agree with me that the biggest advocate for vaccination on social media should have no trouble sharing all of the facts about COVID-19 and children on a very frequent basis. The post first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/open-letter-2/ | 06:30 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: 'Your great-great-great-grandchildren will still be getting immunized against coronavirus': This Mayo Clinic doctor says it's too late to eradicate COVID-19 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/s93tg9/your_greatgreatgreatgrandchildren_will_still_be/ | 07:18 |
| Brainstorm | New from NPR Science: Japan is ramping up COVID-19 restrictions as omicron cases surge: While many Japanese adults are fully vaccinated, few have gotten a booster shot, which has been a vital protection from the highly contagious omicron variant. → https://www.npr.org/2022/01/21/1074647660/japan-is-ramping-up-covid-19-restrictions-as-omicron-cases-surge | 07:28 |
| Brainstorm | New from r/WorldNews: worldnews: An LDS/Mormon chartered flight brought COVID to Kiribati for the first time ever and triggered a lockdown → https://old.reddit.com/r/worldnews/comments/s94feh/an_ldsmormon_chartered_flight_brought_covid_to/ | 07:56 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | January 21, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/s95ox6/daily_discussion_thread_january_21_2022/ | 09:02 |
| redempt1on | https://imgur.com/a/2CFuMap | 10:40 |
| sdfgsdfg | of the 13 people dead in queensland 1 was unvaccinated, 1 was one dose, 8 was 2 dose and 1 was 3 dose. That sort of proves boosters really do work | 10:41 |
| redempt1on | No, they dont | 10:41 |
| redempt1on | the vacccines were epic fails | 10:42 |
| redempt1on | personally know of double vax'd that died regardless | 10:42 |
| redempt1on | Grub. | 10:42 |
| redempt1on | The vaccines don't stop transmission, and they don't fully prevent death. | 10:42 |
| redempt1on | Grub. | 10:42 |
| sdfgsdfg | https://www.dailymail.co.uk/news/article-10425013/Queensland-reports-drop-Covid-numbers-16-031-cases-reports-13-deaths.html?ns_mchannel=rss&ns_campaign=1490&ito=1490 | 10:42 |
| sdfgsdfg | grub ? whas that | 10:42 |
| redempt1on | Grub = rubbish/bullshit/junk | 10:42 |
| redempt1on | THe vaccines weren't even worth the shit that comes out of my ass | 10:43 |
| redempt1on | zero impact on COVID | 10:43 |
| redempt1on | in fact, Just read an article, high cases in 8 months in my province | 10:43 |
| sdfgsdfg | you tell em brother | 10:43 |
| redempt1on | Which is hilarious after 8 months of mask mandates, vaccine mandates | 10:43 |
| redempt1on | ...but that's not all.. | 10:43 |
| redempt1on | my whole province is almost 90 % vaccinated! | 10:43 |
| redempt1on | Where was this 'herd immunity' with the vaccines? 2 vaccines? 3 ? | 10:44 |
| redempt1on | There has been NONE | 10:44 |
| redempt1on | just bullshit lies by mainstream media, governments, fraudci, Dr Boner Henry, Dr Spam, etc | 10:44 |
| redempt1on | The joo lies never end | 10:44 |
| redempt1on | *highest cases | 10:44 |
| sdfgsdfg | whos dr spam | 10:44 |
| redempt1on | Dr Tam | 10:44 |
| sdfgsdfg | tam bam ? lol | 10:45 |
| redempt1on | Adrienne Tam or whatever the fuck her name is | 10:45 |
| redempt1on | the googly eyed asian lady | 10:45 |
| sdfgsdfg | ah | 10:45 |
| redempt1on | that looks autistic | 10:45 |
| redempt1on | We were told for a long time 'dont worry...dont worry at 60-70 % vaccinated we'll have herd immunity" | 10:45 |
| sdfgsdfg | I like asian girls | 10:45 |
| redempt1on | more REMARAKBLE bullshit lies from Anthony Fraudci. | 10:45 |
| redempt1on | And Canadian Govs | 10:45 |
| redempt1on | and Joseph Biden. | 10:45 |
| redempt1on | they just lie... and they lie... and they lie... then they lie some more. | 10:46 |
| sdfgsdfg | we get a loot of asian immigrants here in australia | 10:46 |
| redempt1on | then lie again, then revise/edit what they said orgiinally | 10:46 |
| sdfgsdfg | we are fkn blessed | 10:46 |
| redempt1on | then they lie to cover their lies. | 10:46 |
| redempt1on | I would NEVER live in Australi! | 10:46 |
| redempt1on | Can't own or a shoot a gun?! Not a place for me. | 10:46 |
| redempt1on | it's not about robbign people or killing my ex girlfriends new huband, or robbing banks,etc | 10:46 |
| redempt1on | it's about being to able defend ourselves against a tyraniccal Gov.. if NEED BE | 10:46 |
| sdfgsdfg | lol which state you live in | 10:47 |
| redempt1on | either one that arose in our country... or one that came from abroad. | 10:47 |
| sdfgsdfg | texas or something | 10:47 |
| sdfgsdfg | yeeeeeeeehaaaaaw | 10:47 |
| redempt1on | BC, Canada | 10:47 |
| redempt1on | That's why men keep rifles... | 10:47 |
| redempt1on | not for shootin' niggurs n spickz... it's in case a new HITLER rises to power.... | 10:47 |
| redempt1on | Either HERE... or COMES from somewhere.... | 10:47 |
| redempt1on | Yall Australians be lames... sittin dicks | 10:48 |
| sdfgsdfg | I know you're on meth by the way | 10:48 |
| redempt1on | for a take-over, invasion. | 10:48 |
| redempt1on | Naw. I type fast. Successful. go-getter. | 10:48 |
| redempt1on | Live life in high gear cause I"m not a queer that takes in the rear. | 10:48 |
| aruns | Please stop redempt1on | 10:48 |
| sdfgsdfg | as you wish.. | 10:48 |
| redempt1on | Yall ozzies be lames tho... | 10:48 |
| sdfgsdfg | dont do it more than 6 months though | 10:48 |
| redempt1on | anyone can takeover and own you | 10:48 |
| Brainstorm | New from StatNews: Opinion: What genetic counselors can teach the CDC about communicating uncertainty: In learning to coexist with SARS-CoV-2, we can no longer banish scientific uncertainty. Instead, we must learn to talk about it and live with it. → https://www.statnews.com/2022/01/21/what-genetic-counselors-can-teach-the-cdc-about-communicating-uncertainty/ | 10:48 |
| redempt1on | I know ozzis online... "GOLD" | 10:48 |
| sdfgsdfg | you'll die in 15-20 years | 10:49 |
| redempt1on | guy owns his own video chat room on TC ... "Gold" | 10:49 |
| redempt1on | dopey stoner skater kid with long blonde hair | 10:49 |
| redempt1on | always wears a flat bill | 10:49 |
| redempt1on | I'll die... STRAPPED. | 10:49 |
| redempt1on | with my gun. | 10:49 |
| redempt1on | like a true freedom-loving patriot. | 10:49 |
| redempt1on | cause you know what? | 10:49 |
| sdfgsdfg | depending on your age give or take 5 years, and a plot twist of an immature death possibly in the next 3 years | 10:49 |
| redempt1on | I'd rather die on my feet than die on my knees like a fucking coward | 10:49 |
| redempt1on | y9ou're just jelly I can get drugs and guns | 10:49 |
| redempt1on | and escorts | 10:50 |
| sdfgsdfg | at least take the edge off with alcohol for fucks sake | 10:50 |
| sdfgsdfg | lmao | 10:50 |
| redempt1on | and Australia thinks stuff like "Dr Pepper" is 'hardcore' and should be 'banned' | 10:50 |
| redempt1on | the fuck out of here with your Dr Pepper | 10:50 |
| redempt1on | shit tastes good but aint no 'rush' or buzz | 10:50 |
| savioronl[m] | The Fastest Method To Eliminate The Corona Virus COVID Is Crying Screaming Out Loud https://saviorword.wordpress.com/2022/01/21/the-fastest-method-to-eliminate-the-corona-virus-covid-is-crying-screaming-out-loud/ | 11:04 |
| Brainstorm | New from NPR Science: Nuclear-test monitor calls Tonga volcano blast "biggest thing that we've ever seen": A station to detect nuclear weapons tests picked up the volcanic eruption in Tonga in Antarctica. Some experts say blast could be more than 50 [... want %more?] → https://www.npr.org/2022/01/21/1074438703/nuclear-test-monitor-calls-tonga-volcano-blast-biggest-thing-that-weve-ever-seen | 11:08 |
| Brainstorm | New from Medical Xpress: Poland hits pandemic record of over 36,600 daily infections: Poland's deputy health minister said Friday the nation hit a COVID-19 pandemic record of 36,665 new infections reported in 24 hours. → https://medicalxpress.com/news/2022-01-poland-pandemic-daily-infections.html | 11:38 |
| Brainstorm | New from BMJ: Covid-19: Advice on wider use of FFP3 masks should extend to GPs, BMA says: FFP3 masks should be worn by staff caring for patients with suspected or confirmed respiratory viral infections that are spread by airborne transmission, such as SARS-CoV-2, winter guidance from the... → http://www.bmj.com/content/376/bmj.o176.short | 11:57 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: 'It's a lot for one person:' COVID-19 pandemic puts pressure on Maine home care services: ""Arsenault says they’re testing staff and pairing positive caregivers with positive clients" → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/s98adm/its_a_lot_for_one_person_covid19_pandemic_puts/ | 12:07 |
| Brainstorm | New from ECDC: Weekly epidemiological update: Omicron variant of concern (VOC) – week 2 (data as of 20 January 2022) EU/EEA: As of 20 January 2022, the Omicron variant has been identified in all EU/EEA countries. From 20 December 2021 to 9 [... want %more?] → https://www.ecdc.europa.eu/en/news-events/weekly-epidemiological-update-omicron-variant-concern-voc-week-2-data-20-january-2022 | 13:06 |
| Brainstorm | New from The Atlantic: Will Omicron Protect Us From Future Waves?: Even before Omicron hit the United States in full force, most of our bodies had already wised up to SARS-CoV-2’s insidious spike—through infection, injection, or both. By the end of October 2021, some 86.2 percent of [... want %more?] → https://www.theatlantic.com/health/archive/2022/01/omicron-wave-immunity/621324/ | 13:25 |
| Brainstorm | New from Reddit (test): Covid2019: Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong → https://old.reddit.com/r/Covid2019/comments/s99pbb/monitoring_rodents_for_sarscov2_and_other/ | 13:34 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 21JAN22 → https://old.reddit.com/r/nCoV/comments/s99xbq/global_covid_cases_for_21jan22/ | 13:54 |
| Brainstorm | New from r/WorldNews: worldnews: Oral CBD Prevented COVID-19 Infection in Real-World Patients, Study Suggests → https://old.reddit.com/r/worldnews/comments/s99zxx/oral_cbd_prevented_covid19_infection_in_realworld/ | 14:04 |
| Brainstorm | New from Il Sole 24 Ore: Esoscheletri, app e realtà virtuale: Lecco punta all’eccellenza per la riabilitazione: Politecnico di Milano, Cnr e istituti di ricovero e cura hanno contribuito al progetto Empatia. Al centro della ricerca soluzioni da [... want %more?] → https://www.ilsole24ore.com/art/esoscheletri-app-e-realta-virtuale-lecco-punta-all-eccellenza-la-riabilitazione-AEjF9O9 | 14:43 |
| Brainstorm | New from BMJ Open: Validity of ICD-10 codes for COVID-19 patients with hospital admissions or ED visits in Canada: a retrospective cohort study: Objective To evaluate the validity of COVID-19 International Classification of Diseases, 10th Revision (ICD-10) codes and their combinations. Design Retrospective cohort study. [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/1/e057838 | 15:41 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Alabama tops 45% COVID positivity rate, among highest in nation → https://old.reddit.com/r/Coronavirus/comments/s9bgvj/alabama_tops_45_covid_positivity_rate_among/ | 15:51 |
| oerheks | NL from 39k to 57k new cases | 15:52 |
| Brainstorm | New from BBC Health: (news): Covid-19: 'We'll be second-class citizens if self-isolation rules go' → https://www.bbc.co.uk/news/uk-60072080 | 16:32 |
| Bridgestorm | ❗ 地震 警報 / EARTHQUAKE WARNING for Shikoku, Japan (just felt near Saiki?) — Follow for updates (www.kmoni.bosai.go.jp) | 17:09 |
| Brainstorm | New from Contagion Live: Moderna Vaccine More Effective Than Pfizer-BioNTech at Preventing Infections, Hospitalizations: Among a matched study cohort, Moderna recipients were less likely to experience COVID-19 breakthrough infections and [... want %more?] → https://www.contagionlive.com/view/moderna-vaccine-more-effective-than-pfizer-biontech-at-preventing-infections-hospitalizations | 17:20 |
| Brainstorm | New from ClinicalTrials.gov: (news): Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19 → https://clinicaltrials.gov/ct2/show/NCT05200819 | 17:30 |
| Brainstorm | New from ClinicalTrials.gov: (news): Markers of Severity (CD177,S100A8 &S100A12) in Sever Acute Respiratory Syndrome Coronavirus 2(SARS-COV-2) Patients → https://clinicaltrials.gov/ct2/show/NCT05201625 | 17:39 |
| `St0ner | https://www.theguardian.com/world/2022/jan/21/covid-reinfection-how-likely-are-you-to-catch-virus-multiple-times | 17:43 |
| `St0ner | interesting findings about reinfections | 17:44 |
| lastshell | I been wearing double mask one of fabric other kn95 I don't want to get covid again | 17:54 |
| Tuvix | Yea, that's a good summary of the fairly staggering numbers of variables involved, including community vaccination, prior infections with a variety of varients (or even their sub-varients,) viral load, antibody response, and more. | 17:54 |
| Tuvix | The first "officially reported" death from Omicron in the US was a reinfection from someone who had delta. As a single data-point it's not useful to draw conclusions (and he could well have had other issues going on too) but it only underscores the importance of getting vaccinated even after an initial infection. | 17:55 |
| lastshell | I can tell vaccines save lives | 17:57 |
| lastshell | some family memebrs with diabetis, and with vaccines survived omicron | 17:57 |
| MerlinMp[m] | for some people indeed, for others dont | 17:58 |
| lastshell | well more comorbidities is hard to save sadly MerlinMp[m] | 17:59 |
| booboo1212[m] | I just had a very mild case of covid with 3 shots- thought it was a bad cold with a cough and some fever for a few days. Now testing negative after 6 days at home | 17:59 |
| booboo1212[m] | Others in my office who presumably caught the same variant have been out for weeks- folks who have had no or only a single vaccine shot | 17:59 |
| Tuvix | It's all about odds in aggregate, but I like to load the dice with better odds personally. | 17:59 |
| Tuvix | I'd imagine that causes staffing problems then too, so it's not only bad for the individuals out sick, but the company as a whole at that point. | 18:01 |
| lastshell | is like a /dev/random | 18:02 |
| lastshell | I wish they can find what make more people susceptible | 18:02 |
| MerlinMp[m] | > <@booboo1212:matrix.org> I just had a very mild case of covid with 3 shots- thought it was a bad cold with a cough and some fever for a few days. Now testing negative after 6 days at home | 18:03 |
| MerlinMp[m] | > | 18:03 |
| MerlinMp[m] | > Others in my office who presumably caught the same variant have been out for weeks- folks who have had no or only a single vaccine shot | 18:03 |
| MerlinMp[m] | Sad is that there are people who have mild case of covid without any vax. How do you know if vax had really influence on you? | 18:03 |
| lastshell | MerlinMp[m] I had an uncle who died of covid | 18:04 |
| lastshell | he has obese | 18:04 |
| lastshell | my mom is obese she is fine 3 jabs | 18:04 |
| lastshell | I know is anecdotal data but that all I have | 18:04 |
| Tuvix | MerlinMp[m]: Are you asking generally how can we be sure vaccines are doing their job? The data on who is dying is quite clear on that: https://ourworldindata.org/covid-deaths-by-vaccination | 18:04 |
| MerlinMp[m] | There is some research - unfortunately in Polish that 14% of population have vulnerable genes to covid | 18:06 |
| Tuvix | Have a vaccine is no guarantee just like wearing a seatbelt in a car or a helmet on a bike is, but those things also greatly improve your odds when exposed to a situation they're designed to protect against worse outcomes. | 18:07 |
| Tuvix | MerlinMp[m]: There are a number of studies going on trying to answer some of these questions. It's still very early yet, but there was a really fascinating brain imaging study by UK Biobank which had brain scans from people before COVID was around, and they found potential markers that could potentially be predictive of COVID susceptibly, but the study didn't have enough information to draw more than | 18:08 |
| Tuvix | speculative conclusions here and noted more study would be required in the future. | 18:09 |
| Tuvix | Here's the study if this kind of thing interests you: https://www.medrxiv.org/content/10.1101/2021.06.11.21258690v3 | 18:09 |
| Tuvix | .title | 18:09 |
| Brainstorm | Tuvix: From www.medrxiv.org: Brain imaging before and after COVID-19 in UK Biobank | medRxiv | 18:09 |
| MerlinMp[m] | Maybe we will have a test which shows if youre vulnerable to covid or not-based on tour genetics. The article shows FOXP4 gene as one of the suspected for making the infection lethal | 18:12 |
| Tuvix | It's almost surely not going to be "one gene" that "makes" the infection leathal, no. Biology tends to be far more complex than that. | 18:13 |
| MerlinMp[m] | <lastshell> "Merlin / Młp I had an uncle..." <- I have high BMI and it didnt make my infections worse | 18:14 |
| Tuvix | It's a risk factor, but really you don't know if it made it worse since yours may have been better with fewer factors shown (again, in aggregate) to be significant. That still doesn't mean any individual case will or won't necessarily experience that change in outcome, or as significantlly. | 18:16 |
| Brainstorm | New from ClinicalTrials.gov: (news): To Evaluate Safety & Immunogenicity of DelNS1-2019-nCoV-RBD-OPT1 for COVID-19 in Healthy Adults Received 2 Doses of BNT162b2 → https://clinicaltrials.gov/ct2/show/NCT05200741 | 18:27 |
| LjL | Topol has some new tweets about neurological consequences found in newer studies... I guess I'll have some happy reading for today | 18:36 |
| Brainstorm | New from ClinicalTrials.gov: (news): Physical Activity and the Course of COVID-19 → https://clinicaltrials.gov/ct2/show/NCT05200767 | 18:36 |
| Brainstorm | New from r/COVID19: COVID19: Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by Omicron and Delta Variants → https://www.reddit.com/r/COVID19/comments/s9fyp2/association_between_3_doses_of_mrna_covid19/ | 18:46 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Arcturus Therapeutics Inc: LUNAR-COV19/ARCT-021 → https://covid19.trackvaccines.org/vaccines/20/ | 19:44 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/ | 19:54 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Adimmune Corporation: AdimrSC-2f → https://covid19.trackvaccines.org/vaccines/63/ | 20:13 |
| LjL | Dredd, you may "like" this story, i thought, although i just recalled i was told this by my mom days or weeks ago, and that i was going to tell someone here, but i don't remember the context... anyway, here goes now: if we get a positive rapid test, that's not legally enough to get work leave here or to get your household into justified quarantine. but PCRs may take many days to be processed currently. so what happened to my cousin's boyfriend was when he | 20:19 |
| LjL | contacted his doctor about his positive rapid test, the doctor *discarded a PCR test* just so he could lie and report it as positive | 20:19 |
| LjL | italian bureaucracy and ways around it... for the win? for the lose? i dunno | 20:19 |
| Brainstorm | New from CIDRAP: News Scan for Jan 21, 2022: COVID vaccines and fertility Vaccines and breakthrough COVID-19 Another small dip for US flu More polio in Nigeria → https://www.cidrap.umn.edu/news-perspective/2022/01/news-scan-jan-21-2022 | 20:33 |
| LjL | uhmm, is the cannabis (CBD here specifically) stuff getting a bit more real? there's a new study on Science Advances that looks at a few in vitro mechanisms, but also looks retrospectively at patients taking CBD https://www.science.org/doi/epdf/10.1126/sciadv.abi6110 | 20:49 |
| LjL | Analysis of 1,212 patients from the National COVID Cohort Collaborative (N3C) (28) with a history of seizure- related conditions and a medication record of CBD100 revealed 6.2% (75 patients) with an indication of SARS-CoV-2 infection proximal to the dates of their first COVID-19 test in their N3C data. This was a significantly lower rate than the rates of matched control groups of patients that did not have any CBD100 records (e.g., 6.2% for CBD100 patients | 20:49 |
| LjL | compared to 8.9% for non-CBD100 patients, p = 0.014; multivariable logit model odds ratio (OR) of 0.65, p = 0.009, 95% C.I. [0.47,0.90]) | 20:49 |
| LjL | it looks like quite significant correlation. but, it's retrospective, so i don't know what *other* factors could influence use of CBD | 20:50 |
| LjL | for example it says "An oral solution of CBD 100 mg/mL (CBD100) is often used for the treatment of seizures", i'd naively assume if people taking CBD tend to take it because they have *more* health issues than average, then i'd expect *more* (or worse) COVID, but things can be more complicated than they seem | 20:51 |
| LjL | there's also an article about the study here https://www.news-medical.net/news/20220121/Cannabidiol-found-to-inhibit-SARS-CoV-2-infection-in-human-cells-and-mice.aspx and here https://www.vice.com/en/article/bvn743/oral-cbd-prevented-covid-19-infection-in-real-world-patients-study-suggests?utm_source=reddit.com | 20:51 |
| LjL | “We strongly caution against the temptation to take CBD in presently available formulations including edibles, inhalants or topicals as a preventative or treatment therapy at this time,” the authors write. “Especially without the knowledge of a rigorous randomized clinical trial with this natural product.” | 20:52 |
| LjL | it does seem like there may be enough now to motivate an RCT on it, though | 20:52 |
| LjL | (but who will do it and for what gains?) | 20:52 |
| Brainstorm | New from Politico: Irish scrap pandemic restrictions ‘to be ourselves again’: Prime Minister Martin tells the nation that widespread vaccination has tamed the Omicron threat after 'very dark days.' → https://www.politico.eu/article/ireland-scrap-pandemic-restrictions/ | 20:52 |
| Brainstorm | New from Politico: Code Red: Belgium to use COVID-19 barometer: System will allow authorities to tie coronavirus measures to hospitalization numbers and ICU capacity. → https://www.politico.eu/article/code-red-belgium-adopt-covid-19-barometer/ | 21:02 |
| Brainstorm | New from The Atlantic: Why a 3-Dose Vaccine for Young Kids Might Actually Work Out: For many months now, Pfizer’s COVID-19 vaccine has been slowly making its way into smaller arms in smaller doses—from teens to adolescents to elementary-school-age kids in the fall. Now [... want %more?] → https://www.theatlantic.com/health/archive/2022/01/covid-vaccines-kids-under-5-three-doses/621334/ | 21:21 |
| Dredd | <LjL> "contacted his doctor about his..." <- Lol wtf | 21:45 |
| LjL | Dredd, i don't even know how to consider that. obviously, in a vacuum, discarding tests is bad, and lying legally is bad. but the doctor just did what they could to get their patient and his household the quickest possible leave so they could stop working and quarantine, which is obviously useful to them and to society at large. the alternative would have been to wait maybe a week for the test result | 21:49 |
| LjL | so i'm not sure there was "a good thing" the doctor could do. it's one of those cases where bureaucracy (and testing backlog) prevents an actually good outcome | 21:50 |
| LjL | it seems a bit of a no brainer to me that if you rapid test is *positive*, you should be able to just use that to get work leave | 21:50 |
| LjL | but nope, you need PCR, which takes forever | 21:50 |
| LjL | it's not even like you could easily lie about your rapid test being negative, at least if you get one done at a pharmacy, since pharmacies do release green passes for them | 21:51 |
| LjL | (although i think it would be great if people with almost-definitely-confirmed COVID just didn't have to go to a pharmacy or anywhere) | 21:51 |
| Tuvix | Here one of the big pharmacy chains has drive-through testing where you don't even leave your car. | 22:04 |
| dTal | LjL: is the PCR swab done by a pharmacist? | 22:04 |
| dTal | are the latflow swabs? | 22:05 |
| dTal | I was thinking it could be a measure to prevent people from skipping work by faking positive tests | 22:05 |
| -Bridgestorm- 🌖 Linog! Lindol! Earthquake! 5.4 Mww tremor, registered by 6 agencies, with 41 reports, 3 early, occurred 27 minutes ago (20:43:45 UTC), duing a gibbous moon night, Baganga, Philippines (7.61, 126.65) ± 1 km, ↓61 km likely felt 260 km away (Twitter) | 22:11 | |
| Brainstorm | New from r/Science: science: Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses → https://old.reddit.com/r/science/comments/s9k9rc/cannabidiol_inhibits_sarscov2_replication_through/ | 22:19 |
| Brainstorm | New from Pfizer: Anonymous: Pfizer and OPKO Provide Update on the Biologics License Application for Somatrogon for Pediatric Growth Hormone Deficiency → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-opko-provide-update-biologics-license | 22:38 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Study finds COVID-19 is linked to more diabetes diagnoses in kids: A new CDC study found children who had COVID-19 were 116% more likely to get diagnosed with diabetes a month or more later. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/s9lqj7/study_finds_covid19_is_linked_to_more_diabetes/ | 22:58 |
| Dredd | <LjL> "Peter, i don't even know how..." <- Yeah, I mean wtf less about the doctor and more about the system that requires that ha ha | 23:01 |
| Dredd | UK sick / work leave is quite progressive really | 23:01 |
| Dredd | I know that compared to the US and Canada (less so) it's very good but sort of thought most of Europe was as good or better somehow? | 23:02 |
| Dredd | I used to take CBD in coconut oil by adding it to tea | 23:10 |
| Dredd | I called it weed tea 😛 | 23:11 |
| Dredd | This covid stuff has reminded me I wanted to get some again | 23:11 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): A first analysis shows no differences in hospitalizations for the Omicron lineages BA.2 compared to BA.1 in Denmark.en.ssi.dk/news/news/2022… → https://twitter.com/Marc_Veld/status/1484650419825655813 | 23:18 |
| de-facto | people taking CBD before MAY have a higher probability for some health issue (that motivated taking CBD), so they MAY also have a higher probability of caution for distancing to avoid COVID, so that could be a co-founding factor there | 23:24 |
| de-facto | a real study would use double blinded architecture | 23:24 |
| Brainstorm | New from CIDRAP: High false-negative rate limits value of rapid COVID tests for kids: Mary Van Beusekom | News Writer | CIDRAP News Jan 21, 2022 "With rapid antigen tests, positive results are generally meaningful, but negative results have to be taken with a [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/01/high-false-negative-rate-limits-value-rapid-covid-tests-kids | 23:38 |
| LjL | dTal: no pharmacies don't do PCRs | 23:41 |
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